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1 y in which CO is produced and then used as a metabolic intermediate.
2 n mucosal surfaces through the production of metabolic intermediates.
3 armaceuticals, and also represent endogenous metabolic intermediates.
4 and, in some cases, to small phosphorylated metabolic intermediates.
5 ical pathways by confining toxic or volatile metabolic intermediates.
6 ases, producing xylosyl-xylitol oligomers as metabolic intermediates.
7 ells, resulting in the accumulation of cycle metabolic intermediates.
8 enes can explain the decreases in associated metabolic intermediates.
9 3-oxo-4-cholestenoic acid, one of the first metabolic intermediates.
10 (CoAs) are critical regulatory molecules and metabolic intermediates.
11 umulated sugar-phosphates or to depletion of metabolic intermediates.
12 th amino acids for protein synthesis and for metabolic intermediates.
13 f secondary metabolic pathways by binding to metabolic intermediates.
14 protection against the accumulation of toxic metabolic intermediates.
15 f the flavonoid pathway and utilize the same metabolic intermediates.
16 ich necessitates multiple steps to transport metabolic intermediates.
17 esources into offspring that are mediated by metabolic intermediates.
18 here were corresponding changes in polyamine metabolic intermediates.
20 ention in trypanosomatid protozoa to the key metabolic intermediate 5,10-CH(2)-THF, situated at the j
21 Feeding with excess l-DOPA showed that the metabolic intermediate 5,6-dihydroxyindole reached the h
22 m a key pathway for synthesis of the central metabolic intermediate acetyl coenzyme A (acetyl-CoA) fr
23 de chain of biotin, also produce the crucial metabolic intermediates acetyl-CoA and butyryl-CoA with
24 ism have led to the hypothesis that neuronal metabolic intermediates affect neural outputs that modif
25 expression in vSMCs treated with BaP or its metabolic intermediates alone, and in combination with a
26 stids, and also report copolymer production, metabolic intermediate analyses, and pathway dynamics.
31 educed from the redistribution of label into metabolic intermediates and end products observed when c
32 duced from the redistribution of (13) C into metabolic intermediates and end products when cells were
33 mn produced relatively low concentrations of metabolic intermediates and had a greater proportion of
34 is most probably involves both production of metabolic intermediates and modulation of erythropoietin
35 adioactivity from 14C-labeled compounds into metabolic intermediates and total lipids was examined in
36 unique enzymes by nutrient availability and metabolic intermediates, and describe these properties i
42 echniques to identify diphosphate-containing metabolic intermediates at submillimolar concentrations
44 enzymes required to convert PCP to a common metabolic intermediate before entering the tricarboxylic
45 nstrated clear differences in the pattern of metabolic intermediates between amelanotic and melanotic
46 oid bases and their 1-phosphate are not only metabolic intermediates but also highly bioactive lipids
47 y is gut microbiota-dependent synthesis of a metabolic intermediate called TMA, and subsequent host-d
48 vity measurements, we show that a downstream metabolic intermediate can selectively remove the cataly
49 r, including mechanism-based inactivation by metabolic-intermediate complex formation, competitive in
50 uire accurate isotopic data of intracellular metabolic intermediates for stationary, nonstationary, a
52 These observations fit a model in which the metabolic intermediate formaldehyde is required for net
57 fatty acids (BCFAs), amino acids, and other metabolic intermediates generated from acyl-coenzyme A,
58 ooA were important in the cycling of CO as a metabolic intermediate, global transcriptional analyses
60 signaling pathways through the production of metabolic intermediates has been increasingly noted.
61 kinase isoform (PKM2) reduces the levels of metabolic intermediates important for biosynthesis and i
62 e ability to initiate the synthesis of a key metabolic intermediate in an allosterically regulated fa
64 hether measurement of concentrations of this metabolic intermediate in plasma could provide a new met
65 phosphate to farnesyl diphosphate, a crucial metabolic intermediate in the synthesis of cholesterol,
66 ince trans-aconitate does not appear to be a metabolic intermediate in these cells but forms spontane
70 f vitamin A (all-trans-retinol) and serve as metabolic intermediates in the formation of the visual c
71 Pim occurred as a result of lower levels of metabolic intermediates in the glycolytic and pentose ph
72 applied targeted metabolomics to measure the metabolic intermediates in the most relevant pathways fo
74 rincipally by the adenine nucleotides, other metabolic intermediates, including long chain acyl-CoA e
75 ting fatty acids to acyl-CoAs and downstream metabolic intermediates increases cellular fatty acid up
76 study demonstrates that the known tryptophan metabolic-intermediate indole-3-pyruvate is a proagonist
77 Here, we show that lactate, an important metabolic intermediate, induces browning of murine white
78 s the flow of glucose- and glutamine-derived metabolic intermediates into the Tricarboxylic Acid (TCA
79 as distinct structures compartmentalizing a metabolic intermediate involved in regeneration of the v
81 ly repressing oxidative metabolism genes and metabolic intermediates involved in epigenetic regulatio
82 of <2 s at 100 degrees C, yet this critical metabolic intermediate is found even in organisms that g
83 of defensive compounds are derived from the metabolic intermediate, isopentenyl diphosphate (IPP).
84 to regenerate NAD from NADH by reducing the metabolic intermediate L-lactaldehyde to propanediol whi
86 t is lost during catalysis in a pathway with metabolic intermediates of metal-chelating properties.
87 derangement of many signaling molecules and metabolic intermediates; of these, the massively increas
88 ationship between the two species in which a metabolic intermediate produced by E. coli was used and
90 steps in the pathway that yield the central metabolic intermediates pyruvate and propionyl coenzyme
91 involves the sequestration of sirohaem as a metabolic intermediate rather than as a prosthetic group
92 progression is believed to involve reactive metabolic intermediates reacting with constituents of Br
93 method employs two-photon excitation of the metabolic intermediate, reduced nicotinamide adenine din
94 ng the production of mitochondrial-dependent metabolic intermediates required for cell growth, and th
95 es of M. tuberculosis specifically generates metabolic intermediates reserved for re-initiation of pe
96 s fungal pathogen to synthesize the critical metabolic intermediate S-adenosylmethionine and work by
97 res were treated with trichodiene, the first metabolic intermediate specific to the trichothecene bio
98 e elasticity in permitted pool sizes for key metabolic intermediates such as pyruvate and acetyl-CoA.
100 otein, chlorophyll), total phenols and major metabolic intermediates (sugars, starch, nitrate, amino
103 f protoheme (heme) uses a common set of core metabolic intermediates that includes protoporphyrin.
104 of the CNS monitor and respond to levels of metabolic intermediates that reflect peripheral energy s
105 need to reduce the build-up of thermolabile metabolic intermediates that would be susceptible to des
106 hough 2,6-dichlorohydroxyquinol is a logical metabolic intermediate, the enzyme hardly uses it as a s
107 and chemicals are generated from short-chain metabolic intermediates through pathways that require ca
108 ine, and they actively synthesize and export metabolic intermediates to the apical side to nourish th
109 ustness of the biocatalysts that convert the metabolic intermediates to, in some cases, finished and
110 we demonstrate by mass spectrometry that the metabolic intermediates UDP-GalNGc and UDP-GlcNGc serve
111 atic synthesis of phosphorylated high-energy metabolic intermediates under conditions considered to h
113 ncy of cholesterol and accumulation of toxic metabolic intermediates, we assessed the efficacy of com
116 ely on the tick blood meal for nutrients and metabolic intermediates while residing in the tick vecto
119 mn generated periodic high concentrations of metabolic intermediates, with Bacteria and methanogens d
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