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1 cellulose, pentose sugars from xylan are not metabolized.
2 leaves, raising the possibility that MDA is metabolized.
3 d cellobiose present in the hydrolysate were metabolized.
5 lic nucleotide 3'-phosphodiesterase (CNPase) metabolizes 2',3'-cAMP to 2'-AMP; 2',3'-cAMP is a potent
6 ow that cholesterol epoxide hydrolase (ChEH) metabolizes 5,6-EC into cholestane-3beta,5alpha,6beta-tr
7 AMX-2 is the primary monoamine oxidase that metabolizes 5-HT in C. elegans, and we also found that g
11 physically couple ubiquitin recognition and metabolizing activities for fine tuning of DNA repair pr
12 substrate-specific P450 with high quercetin-metabolizing activity, identified six triazole fungicide
14 confinement, and suggest that the ability to metabolize alkanes may play a role in elastic film forma
17 Albumin, Alpha Fetoprotein, and Fibrinogen, metabolized ammonia, and displayed cytochrome P450 activ
18 Our findings suggest that the ability to metabolize and sense cholesterol and/or fatty acids in p
19 dataset, containing 2000 molecules with 3400 metabolized and 30 000 un-metabolized sites and covering
20 Nevertheless, in vivo, these compounds are metabolized and circulate in the organism as glucuronate
23 atography has shown that they were absorbed, metabolized and released by Caco-2 cells in culture medi
24 hetic amino acid radiotracers, which are not metabolized and therefore more accurately reflect transm
25 r the human body, PEs, BPA, PBs, and OPs are metabolized and/or conjugated and finally excreted via u
29 omerular podocytes and tubular epithelia and metabolizes angiotensin II (AngII), a peptide known to p
31 gh syntrophs have been generally presumed to metabolize aromatic compounds to acetate, CO2 , H2 and f
32 d to 2-(methylthio)ethanol, which is further metabolized as a usable organic sulfur source, generatin
34 This reversal occurs without NO3(-) being metabolized as evidence by lack of any (30)N2 formation
35 bited high free fraction (0.46 +/- 0.02) and metabolized at a moderate rate (39% +/- 5% and 24% +/- 3
37 fects in growth, response to a peroxisomally metabolized auxin precursor, and peroxisomal protein imp
39 viduals, increasing the abundance of lactose-metabolizing bacteria that were responsive to dietary ad
43 acteria, fungi, algae and even higher plants metabolize BPA, but anaerobic microbial degradation has
44 ring homeostasis, differentiated colonocytes metabolized butyrate likely preventing it from reaching
46 he highest TMFs were for OCs that are slowly metabolized by animals (metabolic rate kM < 0.01 day(-1)
49 anolamine and 2-arachidonoyl-glycerol can be metabolized by cyclooxygenase-2 into PG-ethanolamide (PG
51 We hypothesized that cholestanol might be metabolized by CYP46A1, the principal cholesterol 24-hyd
52 xic to Culex mosquito larvae, can be further metabolized by CYP9M10/CPR and CYP6AA7/CPR, with the ult
53 aining population of interneurons; and 4) is metabolized by either monoglyceride lipase, which is loc
54 ise neurotoxic glutamate can be productively metabolized by glutamate oxaloacetate transaminase (GOT)
57 hydroxyphenethylamine), which is a monoamine metabolized by monoamine oxidase (MAO), exists widely in
59 ypothesized that TAG-derived fatty acids are metabolized by peroxisomal beta-oxidation to produce ATP
61 8,9-E-11-HET and ct-8,9-E-15-HET are further metabolized by sEH, with ct-8,9-E-11-HET being hydrolyze
63 ereas the short fatty acids are absorbed and metabolized by the animals, the greenhouse gas methane e
64 t that the Arg that is taken up is primarily metabolized by the arginase pathway to produce the polya
69 s the principal dietary form of selenium, is metabolized by the liver to selenide, which is the form
73 ferulic/isoferulic acids, in addition to non-metabolized caffeoyl-, feruloyl- and p-coumaroilquinic a
75 macrophages are able to bind, scavenge, and metabolize carboxyethylpyrrole derivatives of proteins b
77 drug metabolism, including those involved in metabolizing chemotherapy drugs that are commonly used i
79 A1 gene, which encodes a crucial enzyme that metabolizes cholesterol, 7DHC, and vitamin D, appeared t
80 compartmentalize a common core of enzymes to metabolize compounds via a toxic and/or volatile aldehyd
81 is greatest ( approximately 100%) for slowly metabolized compounds, regardless of KOW, and lowest for
83 r range, without affinity for the major drug-metabolizing CYP2D6 and CYP3A4 enzymes and CYP21A2, with
85 WT POR, as were those of several xenobiotic-metabolizing cytochromes P450, indicating that the A287P
91 under in vitro conditions, serine is mainly metabolized during the replicative phase for the biosynt
92 GSTA4) is a phase II detoxifying enzyme that metabolizes electrophiles and carcinogens including 4-hy
94 arise from the accumulation of incompletely metabolized endogenous nucleic acid species owing to mut
95 of increased expression of the progesterone-metabolizing enzyme 20alpha HSD and reduced nuclear prog
96 and cell-active inhibitors of the (ox)lipid-metabolizing enzyme alpha/beta-hydrolase domain 3 (ABHD3
97 been demonstrated that an efficient cocaine-metabolizing enzyme developed in our previous studies ca
99 vels of human renal allograft methylarginine-metabolizing enzyme gene expression associated with stee
100 as been studied as a regulator of xenobiotic metabolizing enzyme genes, notably cytochrome P4501A1 en
101 We examined if overexpression of the MG-metabolizing enzyme glyoxalase 1 (GLO1) in macrophages a
102 osuppression is the expression of tryptophan-metabolizing enzyme indoleamine 2,3-dioxygenase (IDO).
103 Phosphodiesterase 4 (PDE4) is a key cAMP-metabolizing enzyme involved in the pathogenesis of infl
104 The competition of two drugs for the same metabolizing enzyme is a common mechanism for drug-drug
105 e (DA) and serotonin (5HT) and the monoamine-metabolizing enzyme monoamine oxidase A (MAOA) have been
106 lglycerol lipase (MGL) functions as the main metabolizing enzyme of 2-arachidonoyl glycerol, an endoc
107 omyelin phosphodiesterase 3 (SMPD3), a lipid-metabolizing enzyme present in bone and cartilage, has b
110 Lysosomal acid lipase is an essential lipid-metabolizing enzyme that breaks down endocytosed lipid p
111 chrome P450 3A4 (CYP3A4) is a key xenobiotic-metabolizing enzyme that oxidizes and clears the majorit
112 cytochrome P450 3A4 (CYP3A4), the major drug metabolizing enzyme, by dietary compounds has recently a
113 ction of the specific high-affinity fructose-metabolizing enzyme, fructokinase, in an experimental se
116 pothesized that animals deficient in the SNO-metabolizing enzyme, S-nitrosoglutathione reductase (GSN
119 , and 102,270 were genotyped for the alcohol-metabolizing enzymes alcohol dehydrogenase 1B (ADH-1B; r
120 urvival actions seen after modulation of S1P-metabolizing enzymes allows this axis to emerge as a new
121 ulates the expression of genes encoding drug-metabolizing enzymes and drug transporters to essentiall
125 on and maturation process, and expression of metabolizing enzymes and transporter were also increased
135 bound oxidative partners, including the drug-metabolizing enzymes of the cytochrome P450s (P450).
137 ate that loss-of-function variants in folate-metabolizing enzymes strain cellular PC production, poss
139 fold defines a large family of nucleic acid metabolizing enzymes that catalyze phosphoryl transfer r
140 we have investigated the role of nucleotide-metabolizing enzymes that regulate the extracellular bal
141 EA and 2-AG was achieved by inhibiting their metabolizing enzymes URB597 (a fatty acid amide hydrolas
142 ses were dependent on induction of vitamin A-metabolizing enzymes via the beta-catenin/T-cell factor
143 ) comprise a diverse family of phase II drug metabolizing enzymes whose shared function is the conjug
144 s (FMOs) are primarily studied as xenobiotic metabolizing enzymes with a prominent role in drug metab
145 backbiting conversion without a reliance on metabolizing enzymes, and o(LA)n-PTX improves PTX delive
146 that HPr interacts with several carbohydrate-metabolizing enzymes, but whether HPr plays a regulatory
147 ty offset against the other glucosylceramide metabolizing enzymes, glucosylceramide synthase (GCS), l
148 rotein levels, but not mRNAs levels, of EtOH-metabolizing enzymes, including alcohol dehydrogenase 1,
150 regnane X receptor (hPXR) to upregulate drug-metabolizing enzymes, resulting in decreased drug effica
151 control of the S-nitrosylation level of ROS-metabolizing enzymes, thus modulating the extent and vel
156 nsformations accurately, focusing on nitrile metabolizing enzymes: nitrile hydratase (NHase) and amid
159 sotope-labelled compounds, we confirm NMN is metabolized extracellularly to NR that is then taken up
160 her doses exceed the physiologic capacity to metabolize FA and result in the preferential uptake of F
164 dividual genes and gene networks involved in metabolizing fenbendazole (FBZ) and flunixin meglumine (
165 phylococcus aureus, in concert with an NO(*)-metabolizing flavohaemoprotein, regulates electron trans
167 se and two terminal oxidases, which serve to metabolize formate and facilitate the use of oxygen as a
168 e declines in PFOS exposure for species that metabolize FOSA, including seafood consuming human popul
170 recombinant mouse CCP5, we confirmed that it metabolized gamma-carboxyl-linked glutamate of synthetic
172 e-nucleotide polymorphisms (SNPs) in alcohol metabolizing genes (ADH1B/ADH1C/ADH5) and two loci in KL
173 tion between alcohol consumption and alcohol metabolizing genes and KLB, and identifies novel gene as
178 ed glucose uptake, GLN addicted cells do not metabolize glucose via the TCA cycle when GLN is deplete
180 , the budding yeast Saccharomyces cerevisiae metabolizes glucose predominantly by glycolysis and ferm
181 olic reprogramming included a higher rate of metabolizing Gly, which provides additional evidence tha
184 vation was supported in VA-13 cells, an EtOH-metabolizing human hepatoma cell line, which displayed m
185 deeper insights into how glucosinolates are metabolized in cruciferous plants and reveal variation o
187 gs demonstrate that methylone is extensively metabolized in rats, but MDC is the only centrally activ
188 l from peripheral tissue, carried by HDL, is metabolized in the liver after uptake by the HDL recepto
189 of vitamin D, vitamin D3 and vitamin D2, are metabolized in the liver through hydroxylation to 25-hyd
191 indicates that some aroma compounds could be metabolized in the oral cavity in an individual manner,
192 study suggested that TeDB-DiPhOBz is slowly metabolized in vitro, and also indicated that if wild he
195 mation, and evidence of a higher capacity to metabolize inorganic As was negatively associated with a
198 Cu ligand, was first injected to allow it to metabolize into diethyldithiocarbamate (DDC), a strong (
199 a murine model of diabetes that netrin-1 is metabolized into a bioactive fragment corresponding to d
201 on of (13)C-glucose or D3-acetate, which are metabolized into acetyl-coA, labeling acetyl groups thro
205 Consequently, only GOX3 can efficiently metabolize l-lactate at low intracellular concentrations
207 Thus, we identified GOX3 as the enzyme that metabolizes l-lactate to pyruvate in vivo and hypothesiz
208 rected modulation of the colonic bacteria to metabolize lactose effectively is a potentially useful a
211 t bees consuming quercetin with myclobutanil metabolized less quercetin and produced less thoracic AT
212 omonas paucimobilis, a bacterial strain that metabolizes lignin-derived aromatics, was previously ava
213 surface of leukocytes and endothelial cells metabolizes locally released, intravascular ATP and ADP,
219 ning of tracer derivatives from concurrently metabolized native and uniformly labeled tracer substanc
220 glutamate oxaloacetate transaminase (GOT) to metabolize neurotoxic glutamate in the stroke-affected b
221 ntly regulates the rate of NO consumption by metabolizing NO in an O2-dependent manner with decreased
222 rcent to 15% of glucose used by the brain is metabolized nonoxidatively despite adequate tissue oxyge
224 symbiosis as a strategy for an herbivore to metabolize one of nature's most complex polysaccharides
227 ent advances have revealed that enzymes that metabolize or modify endogenous nucleic acids are essent
228 mino acids in a biological system are either metabolized or incorporated into free amino acids (FAAs)
229 (TPP)-dependent oxalate oxidoreductase (OOR) metabolizes oxalate, generating two molecules of CO2 and
231 in the cerebellum of cholesterol/cholestanol-metabolizing P450s from a pool of metabolically availabl
233 lism is widely accepted, the role of ammonia metabolizing pathways in the liver for maintenance of wh
234 eatment samples may be a nonstaining, slowly metabolizing phenotype better adapted to airborne transm
235 that microbial communities have to adapt to metabolize photo-altered DOC.The role of dissolved organ
238 cytosolic carboxypeptidase (CCP) family that metabolizes polyglutamate side chain and its loss result
243 e, nonpersistent, semivolatile chemicals are metabolized quickly, and urine is the compartment with t
244 in the absence of APA suggests a protective metabolizing role of APA in AngII-mediated glomerular di
245 these compounds are often only incompletely metabolized, significant amounts contaminate the aquatic
247 olecules with 3400 metabolized and 30 000 un-metabolized sites and covering nine Cytochrome P450 isoz
248 n want to know which atoms of a molecule-its metabolized sites-are oxidized by Cytochrome P450s in or
250 ng the ability to acquire certain nutrients, metabolize specific substrates, or maintain intracellula
251 genic bacterial species Streptococcus mutans metabolizes sucrose to initiate biofilm formation on the
252 of lignin, and it also lacks the ability to metabolize sugars or organic acids; (ii) the CO2 release
254 ly uFBA predicts that stored red blood cells metabolize TCA intermediates to regenerate important cof
256 on cancer models, we found that bacteria can metabolize the chemotherapeutic drug gemcitabine (2',2'-
257 ndividual variability exists in how patients metabolize the drug (pharmacokinetics) and the magnitude
259 acteria dwelling in an animal's scent glands metabolize the glands' primary products into odorous com
260 gut bacteria orchestrate manifold enzymes to metabolize the most challenging glycan in the human diet
262 P2C8, an important member of this subfamily, metabolizes the anticancer drug paclitaxel, certain anti
263 ha-carboxyl-linked glutamates, CCP5 uniquely metabolizes the gamma-carboxyl linked, branch point glut
265 standing of how the differential capacity to metabolize these bioactive compounds affect health outco
266 eveals that B. phytofirmans PRF is poised to metabolize thiosulfate to sulfite in a sulfur assimilati
268 romatic and hydroaromatic compounds that are metabolized through the beta-ketoadipate catabolic pathw
269 alysis revealed that PCB 51 and PCB 102 were metabolized to 2,2',4,6'-tetrachlorobiphenyl-3'-ol (OH-P
273 sed during blood meal digestion is partially metabolized to facilitate the disposal of excess nitroge
275 robic glycolysis, pyruvate is preferentially metabolized to lactate by the enzyme lactate dehydrogena
277 lta(9)-tetrahydrocannabinol (Delta(9)THC) is metabolized to only one major active metabolite, it has
279 The majority of retinaldehyde is further metabolized to retinol (vitamin A), esterified and packa
282 homeostasis in the native state, but can be metabolized to sphingosine-1-phosphate (S1P), linked to
283 formate (i.e., while the lactate was mainly metabolized to support the cell growth, the formate was
285 g ripening, a considerable amount of HDMF is metabolized to the flavorless HDMF beta-d-glucoside.
286 ereomer in biological tissues because it was metabolized to the lowest degree and also accumulated fr
287 lysis in this region suggested CYP1A2, which metabolizes tobacco-derived carcinogen, as a causative c
288 The microbiota from Card9(-/-) mice fails to metabolize tryptophan into metabolites that act as aryl
289 capability of microbes to utilize mucins and metabolize tryptophan is diminished in IBD patients.
291 with three Lactobacillus strains capable of metabolizing tryptophan or by treatment with an AHR agon
293 Besides being oxidized, glucose was mainly metabolized via glycerol production and release and lipi
295 es; ss- and gamma-HBCD were both extensively metabolized via pathways of stereoisomerization, oxidati
296 umor microenvironment acquire the ability to metabolize vitamin A to produce retinoic acid (RA), whic
298 ia polyphenols were absorbed and extensively metabolized with tmax of anthocyanins and other polyphen
300 utating ISU1 or SSK2 improved the ability to metabolize xylose of yeast cells without adaptive evolut
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