ライフサイエンスコーパス: metal center

1 from a difluorocarbene insertion on a cobalt metal center.

2 nstead of an electronic interaction with the metal center.

3 t turnover-limiting hydrogen transfer to the metal center.

4 trol the catalytic activity of the adjoining metal center.

5 t now from the porphyrin ring instead of the metal center.

6 ate moiety, linker, phosphane coligands, and metal center.

7 t changing the oxidation state of the apical metal center.

8 agostic coordination of a Me-Si group to the metal center.

9 vinylallene fragment is pushed away from the metal center.

10 ns because of a loss or decomposition of the metal center.

11 xperimental marker for the spin state of the metal center.

12 ive addition of the C(8)-halogen bond to the metal center.

13 d reformation of nacnac ligands bound to the metal center.

14 ichiometrically oxidized by one electron per metal center.

15 uences resulting in product release from the metal center.

16 for inhibitors that compete with 2OG at the metal center.

17 its gel-sol transition upon oxidation of the metal center.

18 rtion of CO2 into a C-H bond remote from the metal center.

19 comparison with phosphorus to the transition metal center.

20 ain and regulates multiple properties of the metal center.

21 ld communicate with residues surrounding the metal center.

22 mechanism with concomitant oxidation of the metal center.

23 e side chains and the steric crowding at the metal center.

24 rmediate by coordination of the arene to the metal center.

25 itude of the potential is independent of the metal center.

26 on to or instead of the XeF(2) attack at the metal center.

27 functionalization after transfer to a second metal center.

28 thin ~8 A of a phosphorothioate-bound Pt(II) metal center.

29 rs to many of the processes occurring at the metal center.

30 ntaining a water molecule as a ligand of the metal center.

31 ihydrogen is bound to a subvalent transition metal center.

32 binding of the counteranion to the cationic metal center.

33 n delocalized in the ligands surrounding the metal center.

34 tructure of a BMC shell protein containing a metal center.

35 te reductive elimination from a destabilized metal center.

36 judicious choice of N,O-chelating ligand and metal center.

37 the spin is localized almost entirely on one metal center.

38 hanol), has been prepared with indium as the metal center.

39 in the immediate vicinity of the transition metal center.

40 ectron transfer at a well-defined transition metal center.

41 M(II)4L6 assembly with facially coordinated metal centers.

42 involving hemilabile ligands and transition metal centers.

43 lanar molecules, a typical geometry for d(8) metal centers.

44 anes and into molecules containing up to 200 metal centers.

45 a partially deprotonated bridge between two metal centers.

46 ic agents through PET utilizing redox-active metal centers.

47 ut involving higher oxidation states for the metal centers.

48 e in the underlying oxidation numbers of the metal centers.

49 Oslo) with coordinatively unsaturated active metal centers.

50 c frameworks and other MOMs with unsaturated metal centers.

51 ssfully coordinate to both Pd(II) and Ru(II) metal centers.

52 within a distribution of inactive spectator metal centers.

53 that are comparable to those of unsaturated metal centers.

54 metal-organic framework (MOF) featuring open metal centers.

55 examer and nonamer with alternating Ru/Ru/Fe metal centers.

56 rdinate the cyclic framework to a variety of metal centers.

57 nd the functional Lewis acid strength of the metal centers.

58 gen and silicon-hydrogen bonds to transition metal centers.

59 licated in a range of catalytic processes at metal centers.

60 om the electronic delocalization through the metal centers.

61 obe the early stages of hydride formation at metal centers.

62 t includes a cyclooctyne ligand bridging two metal centers.

63 elective alkyne-alkyne coupling, followed by metal-centered [4 + 2] rather than stepwise alkene inser

64 ridine substrate (both free and bound to the metal center), absorptive signals are observed from hype

65 can be described as interactions between the metal center (active site) and the surface functionality

66 cts as a directing group by chelating to the metal center, affords a potential route for the transfor

67 roduced in the absence of FdhD contains both metal centers, albeit the molybdenum cofactor is at a re

68 dicious choice of the organic linker and the metal center allows the binding energy to be tuned from

69 stematic variation of the BPI ligand and the metal center along with mechanistic investigations of th

70 l contraction in all bond lengths around the metal centers, along with diagnostic shifts in the spect

71 The role of cooperativity between a reduced metal center and a Lewis acid center in small-molecule a

72 action of the sulfur-based orbitals with the metal center and are demonstrated to be useful reporters

73 d, which lacks pi-donor stabilization of the metal center and consequently has a very small HOMO-LUMO

74 tion of a proton from the bound water to the metal center and finally an alpha-H abstraction to relea

75 fragment can be protonated to reoxidize the metal center and generate Tp'PtMe(2)H, the synthetic pre

76 dielectric environment that is close to the metal center and protected from solvent exchange.

77 ive assignment of the stereochemistry at the metal center and reveal secondary coordination sphere in

78 Thus, subtle changes in the porphyrin metal center and ring conformation may influence the ago

79 es the terminal PN O atom (farthest from the metal center and ring core), effecting O-O cleavage, giv

80 ch a combination of the steric pocket of the metal center and substrate size determines the reaction

81 e proximity of the chiral information to the metal center and the ability to switch between S and O c

82 zation in which C-H activation occurs at one metal center and the activated moiety undergoes function

83 include an interaction between the platinum metal center and the surface oxygen atoms.

84 ble chain transfer between active transition-metal centers and excess equivalents of inactive main-gr

85 ared alpha-cationic arsines toward different metal centers and their reactivity in the presence of st

86 halide/pseudohalide anions are bound to the metal centers and thus stationary, the cations move free

87 cepting electrons to activate substrates and metal centers and to enable new reactivity with both ear

88 networks that have coordinatively saturated metal centers and two distinct types of micropores, one

89 The finding that the reduction is metal-centered and causes a decrease in FeNO covalency i

90 I)4L6 assembly with meridionally coordinated metal centers, and a C3-symmetric self-included M(II)4L6

91 and concentration of products, reduction of metal centers, and chemical environments of the organic

92 ted access to multiple structurally integral metal-centers, and options for modifying the microenviro

93 catalyst benzyl groups expand the "cationic" metal center-anionic sulfated oxide surface distances, a

94 tly, reducing the coordination number of the metal centers appears to increase axial magnetic anisotr

95 er a distal (3-substituent furthest from the metal center) approach.

96 H(-) or Cl(-), bound to the lower coordinate metal center are supported through the hydrogen-bonding

97 Three of the metal centers are coordinated to our previously reported

98 metal coordination sphere, whereas when the metal centers are Cu(II) or Zn(2+), the triazole groups

99 d timescales and d(2) nature of the vanadium metal centers are inconsistent with a Peierls driving fo

100 ulas but differ in the geometry in which the metal centers are linked through a central phenyl ring.

101 To be more specific, when the two complexed metal centers are monovalent copper(I) centers, the tria

102 es, isolated chemisorption sites on the CuPc metal centers are observed in STM images.

103 ienyl ring embedded in the fullerene and the metal centers are observed, ranging from eta(1) with a s

104 is widely thought that the properties of the metal centers are primarily determined by the small frac

105 d functionalization at group 8-10 transition metal centers are reviewed.

106 t switches from a dinuclear to a mononuclear metal center as phosphates are eliminated from substrate

107 zation of charge for meta-Fe2 on to a single metal center, as compared with charge delocalization ove

108 or electrochemical communication between the metal centers, as a function of layer thickness and appl

109 dox response of the bipyridine ligand and Ru metal center at negative potentials, as well as the inhi

110 tion is demonstrated for a single main group metal center at room temperature.

111 tly to the degree of electron density at the metal center because they occur with different turnover-

112 led both complexes to be dimeric, having two metal centers bridged via bis(mu-chlorido) linkages.

113 erine revealed binding interactions near the metal center but did not identify a binding pocket for t

114 for ligand exchange reactions not only at a metal center, but also at main group elements.

115 heteroditopic ligand capable of chelating a metal center by way of covalent and noncovalent bonding,

116 uggest that O2 activation occurs on a single metal center, by an oxidative addition on the quartet su

117 o mediate electron hopping between high-spin metal centers, by providing the first example of an Fe c

118 ngle-atom catalysts with full utilization of metal centers can bridge the gap between molecular and s

119 is a lack of model system for understanding metal-centered catalysis on the basal planes.

120 s, but biochemical measurements only suggest metal-centered catalytic electron transfer.

121 ation to the 2-acyl imidazole substrate, the metal-centered chirality is maintained throughout the ca

122 proteins, which illuminate the influence of metal-centered chirality on these interactions.

123 hat provide the reactivity of the introduced metal center combined with specifically intended product

124 d porous crystalline materials comprising of metal centers coordinated to organic linkers.

125 e characterize the impact of chloride on the metal center coordination and reactivity of the fatty ac

126 The spectator metal center could even be replaced entirely with an org

127 carbon nanospheres containing porphyrin-like metal centers (denoted as "PMCS") are successfully synth

128 The local geometry at the metal center depends on the metal ion employed, with Cu(

129 t to a weak covalent interaction between the metal centers, despite a large separation.

130 sights into unforeseen rearrangements of the metal center during catalysis.

131 ns and an interrogation into the fate of the metal center during this interesting transformation.

132 e/reductive coupling occurring at transition metal centers during C-H activation but are also in the

133 l porphyrin-based excitation, some involving metal centered electronic configuration changes that cou

134 the case of polymorphs), and their saturated metal centers eliminate open metal sites from dominating

135 plex according to MD simulation-in which the metal centers embed in the lipid head group region and t

136 This interplay of multiple metal centers enables introduction of an orthogonal alky

137 hemisphere for binding of ligands across two metal centers, enabling the characterization and compari

138 the C-C single bond that interacts with the metal center, establishing a temperature-dependent equil

139 onstrate that a loop (L2) 20 A away from the metal center exerts allosteric control over the cluster

140 moiety on the triple bond coordinated to the metal center followed by alkoxycarbonylation.

141 e of the solvent-derived ligand, priming the metal center for reduction and subsequent O2 binding.

142 essential ligands for the catalytic Mn4CaO5 metal center for water oxidation by PSII.

143 ompared with charge delocalization over both metal centers for para-Fe2.

144 ectrons: the electronic configuration of the metal center has to provide occupied or empty orbitals t

145 The low reorganization energy in these metal centers has been accounted for by assuming that th

146 l-organic frameworks (MOFs) with unsaturated metal centers has not been identified.

147 bilities of these compounds to interact with metal centers have been probed through the coordination

148 studies suggest that gas binding to the iron metal center heme may drive alterations in REV-ERB activ

149 preciate that COX relies on its redox-active metal centers (heme a and a3, CuA and CuB) to reduce oxy

150 t electron-donating Y groups destabilize the metal centered HOMO.

151 metallotetraphenylporphyrins with different metal centers (i.e., Co(II), Co(III), Zn(II), Ni(II), Cu

152 lations, provide evidence for a d(3) iron(V) metal center in a low spin (S = 1/2) electron configurat

153 o a conserved His228 residue adjacent to the metal center in ACMSD from Pseudomonas fluorescens (PfAC

154 ighly distorted CO2 molecule is bound to the metal center in an eta(2)-C,O coordination mode, thus es

155 blishes P*-cluster as a catalytically active metal center in Eu(II)-DTPA-driven reactions.

156 re His200 residue, and the spin state of the metal center in facilitating O(2) binding and activation

157 y, we showed that substitution of the Mn(2+) metal center in human Arginase I with Co(2+) (Co-hArgI)

158 iled mechanism of mechanical disruption of a metal center in its native protein environment in aqueou

159 requirement for generation of an unsaturated metal center in migration chemistry.

160 complexes and suggests a contribution of the metal center in the catalytic cycle.

161 induced state, governing the features of the metal center in the copper-loaded protein, does not requ

162 lly whether distal regions can influence the metal center in the diabetes drug target mitoNEET.

163 endo protonated isomers with respect to the metal center in the former, which is essential to attain

164 xed as carbonate and bound to the equatorial metal centers in both the Zn5 L6 and Cd5 L6 assemblies,

165 monstrate the marked effect of electron-rich metal centers in enabling higher oxidation state pathway

166 onditions based on similar principles as the metal centers in enzymes.

167 Metal centers in metalloproteins involve multiple metal-

168 ue to investigating the rupture mechanism of metal centers in metalloproteins with unprecedented reso

169 ings have been made with as many as fourteen metal centers in the cyclic structure.

170 in (S = 1/2) electronic configuration of the metal centers in the desolvated framework is supported b

171 = 89200 g.mol(-1)) composed of d(5)-vanadium metal centers in the main chain, making it a rare exampl

172 can estimate the percentage of electroactive metal centers in the surface layer.

173 presence of a cooperative effect of the two metal centers in the transformation of CO2.

174 lies in the very different geometries of the metal centers in the transition state.

175 latter makes the emission progressively more metal-centered in the order 1b < 1c < 1d.

176 norbornane) sigma-bound to a d(8)-rhodium(I) metal center, in which the chelating alkane ligand is co

177 In all examples, the incorporation of the metal center into the pincer ligand decreases the NICS(1

178 t on the successful incorporation of the tin metal center into the zeolite framework.

179 This moves the Fe(II) center and two Pt(II) metal centers into and out of communication with each ot

180 The incorporation of metal centers into the backbone of polymers has led to t

181 llic clusters enabled differentiation of the metal centers involved in oxygen atom transfer (Mn) or r

182 part of the coordinating fragments when the metal center is 5-coordinate or be not at all involved i

183 They are present only when the metal center is attached to the surface via a flexible l

184 e in volumetric adsorption capacity when the metal center is changed.

185 r palladium complexes, wherein only a single metal center is directly involved in the catalysis.

186 In its perfect crystal structure, each Zr metal center is fully coordinated by 12 organic linkers

187 facile reductive elimination from the nickel metal center is induced via a photoredox-catalyzed elect

188 Each metal center is monovalent, rigorously linear, and two-c

189 The metal center is not directly involved in the catalytic b

190 egy for the control of electron density at a metal center is reported, which uses a remote chemical s

191 Thus, the choice of metal center is shown to be crucial in determining the l

192 ile a mainly d(z)(2) orbital centered on the metal center is the corresponding donor.

193 r (FLP) solely constructed around transition metal centers is described in this work.

194 n catalyst containing only vanadium atoms as metal centers is reported.

195 omometallic ring containing an odd number of metal centers is reported.

196 acterial ferredoxins, enclosing an Fe(4)S(4) metal center, is an attractive candidate for such an ear

197 all structures and typically containing the metal center itself, one or several parts consisting of

198 r systems indicate that the proximity of the metal centers leads to the observed inhibitory effect on

199 into two structural types: grids, where the metal centers lie in a single plane, and cages.

200 ulations that show that modifications to the metal center, ligand, or even tuning the overall binding

201 hat chloride binding triggers changes in the metal center ligation: chloride binding induces the prop

202 ty and linear ranges were insensitive to the metal centers (M = Cu(2+), Zn(2+), and Pt(2+)) of the po

203 vide three MTAPc complexes bearing different metal centers (M = Cu(2+): CuTAPc, M = Zn(2+): ZnTAPc, a

204 e protonation/oxidative deprotonation of the metal centers may serve as a new chemical precedent for

205 ive stereochemical communication between the metal centers mediated by the rigid 3-fold-symmetric fac

206 trong antiferromagnetic coupling between the metal centers, mediated by the oxo groups, exists in the

207 on-soluble clusters consist of four coplanar metal centers, mutually bridged by single nitrogen atoms

208 We report the observation of two transition-metal-centered nine-atom boron rings, RhB(9)(-) and IrB(

209 binaphthol ligand acts as bridge between the metal centers (Novak's model) is more stable than the di

210 is that electronic coupling between the two metal centers occurs through the bonds of the organic li

211 w strategy using cis-edge or -corner sharing metal-centered octahedra is described which enables inte

212 ure are built of cis-edge or -corner sharing metal-centered octahedra, thus they can be used to targe

213 a feasible ligand that can coordinate to the metal center of Cp*RhCl to accelerate the cleavage of th

214 suggest that the binding of chloride to the metal center of HctB leads to a conformational change in

215 ases with decreasing electron density at the metal center of the Ir catalyst, but that the rate of be

216 ive to the degree of electron density at the metal center of the Ir catalyst.

217 nt of substrate discrimination at the buried metal centers of metalloenzymes.

218 onfiguration in which each cage contains two metal centers of opposite handedness to the other two, w

219 ons, enabled selective interactions with the metal centers of phthalocyanines 7, 12, 9, and 15.

220 TEMPO coordinates to the metal centers of the 16-electron species CpCo(CO) and Fe

221 ion that HoxR avoids oxidative damage of the metal centers of the MBH, in particular the unprecedente

222 Although such metal centers of uniform oxidation states have been achi

223 cycle and demonstrates the influence of the metal center on the mechanism of reaction.

224 Rational, systematic tuning of single-site metal centers on surfaces offers a new approach to incre

225 The metal-centered one-electron oxidation of this Mn(IV) spe

226 tion of electron density from the transition-metal center onto the cage.

227 ers a proximal (3-substituent closest to the metal center) over a distal (3-substituent furthest from

228 PP1 inhibition involves metal center oxidation rather than the thiol oxidation t

229 ery oxidation-resistant, yet promotes facile metal-centered oxidation to form stable Ir(IV) compounds

230 action and Mossbauer spectroscopy indicate a metal-centered oxidation.

231 , and DFT calculations, all of which confirm metal-centered oxidation.

232 ahedral cage connected to a single exohedral metal center (POBBOP)Ru(CO)2 (POBBOP = 1,7-OP(i-Pr)2-2,6

233 ) electrochemical cells demonstrate that the metal center preferentially reduced and its location in

234 Metal centers present on surfaces as well as in homogene

235 t a high catalytic activity by isolating the metal center, preventing bimolecular decomposition paths

236 opriately sized linkers between carbon and a metal center provides a means to modulate the length and

237 luation of their reactivity toward different metal centers provides evidence that the dicationic frag

238 operties expected for M(II) species and with metal-centered radical character.

239 ge of a C-H bond is accomplished by a single metal-centered radical.

240 competes with substrates for binding to the metal center, rationalizing its inhibitory effect.

241 n crystals taken during X-ray radiation show metal center reduction, but indicate development of a st

242 lophen)] results in both ligand centered and metal centered reduction affording the Co(I)-Co(II)-Co(I

243 cert with DFT calculations suggest a largely metal centered reduction of 1 to form the low spin (S =

244 i, Na, K) leads to either ligand-centered or metal-centered reduction depending on the alkali ion.

245 The observed metal-centered reduction leads to distinct reactivity pa

246 the interactions controlling the geometry at metal centers remain often elusive.

247 The coordination environment of the metal center remains intact in the presence of apoTf and

248 omplex possesses an unpaired electron on the metal center, rendering it likely that catalysis takes p

249 ethyl (OH-CH2-) moiety of 5hmC points to the metal center, representing the reaction product of 5mC h

250 Specifically, in the crystal phase a Pt(IV) metal center resulting from Fe <-- Pt backward electron

251 fer of an electron from the adsorbate to the metal center, resulting in reduction of the metal cation

252 n: association of the target analytes to the metal center results in approximately 1000-fold enhancem

253 In metalloproteins, metal centers serve as active sites for a range of funct

254 nsfer ((1)MLCT) excited state into a quintet metal centered state ((5)MC) as has been observed for pr

255 ation of the (3)MLCT state through low-lying metal-centered states.

256 ng effects between xylene methyl groups: the metal-centered stereochemistry was not observed to affec

257 -O) core induces a cascade wherein all three metal centers switch from high-spin Fe(3+) to low-spin F

258 oxidation state and structure of single-site metal centers that are in contact with a metal surface m

259 a targeted oxidative inactivation of the PP1 metal center, that sustains eIF2alpha phosphorylation to

260 hort-distance ET irrespective of the type of metal center, the surface electrostatic potential, and t

261 2, 6, and 7 are equivalent to the number of metal centers, the dinuclear complexes 3, 4, and 5 exhib

262 When paired with a rhodium metal center, these bis(diazaphospholane) ligands are hi

263 le oxidative reactions at a formally Ir(III) metal center through a hydrazido(2-)/isodiazene valence

264 nd is coordinated to the pseudosquare planar metal center through two sigma-C-H bonds.

265 to the basic heteroatom directs the reactive metal center to a specific C-H bond.

266 tion on nitric oxide activation by an Fe(II) metal center to be studied.

267 to attain suitable proximity to the reduced metal center to generate H2.

268 nduces migration of a benzyl ligand from the metal center to the C(carbine) atom.

269 nce of the migration of the hydride from the metal center to the Calpha atom of the alkylidyne.

270 nsfer of electron density from the catalytic metal center to the CO ligand oriented trans to the alky

271 t is accompanied by charge transfer from the metal center to the organic substrate.

272 it is found that Fe and Co are the best MHP metal centers to catalyze these reactions.

273 n and the stoichiometric ratio of rare-earth metal centers to ligands, a hierarchic assembly with dod

274 gen cleavage and hydrogenation by transition-metal centers to produce ammonia is central in industry

275 II), Rh(I), and Cu(I) were used as spectator metal centers to tune the reactivity of the actor ligand

276 The ability of redox-active metal centers to weaken the bonds in associated ligands

277 l oxygen atom could be rotated away from the metal center, to a hydrophobic pocket formed by Ala212,

278 lts demonstrate that modulating a transition metal center via a direct interaction with a Lewis acidi

279 wed by chloride delivery from Me3SiCl to the metal center via a six-membered transition state (IV) th

280 The coordination of H2 to a metal center via polarization of its sigma bond electron

281 ct binding, as well as the inhibition of the metal center via reversible coordination of either a sub

282 The preferred gas adsorption on the metal center was confirmed by neutron diffraction measur

283 state for transfer of the S-H proton to the metal center was located with a computed free energy of

284 bserved when the reduction potential for the metal center was poised near 1000 mV, reflecting the dif

285 n complexes displaying a site-differentiated metal center was synthesized.

286 ange (>2 nm) stereochemical coupling between metal centers was observed, which was minimally diminish

287 series of TRI-EH peptides mutated below the metal center, we use a variety of spectroscopies (EPR, U

288 three formal multiply bonded ligands to one metal center where the coordinated heteroatoms derive fr

289 he transfer of electrons to the redox active metal centers where O2 is reduced to water.

290 sulfenic acids (P-SOH) or the involvement of metal centers which would facilitate the oxidation of H2

291 ironment and the nature of the spin-carrying metal center, which is further subject to modifications

292 aramagnetic species, and to bind strongly to metal centers, which gives rise to very robust catalysts

293 attice oxygen atoms to reoxidize the reduced metal centers while the gaseous O2 reactant replenishes

294 aves were attributed to the oxidation of the metal centers, while the remaining one is due to the oxi

295 exchange of THF molecule coordinating to the metal center with isonitrile, whereas insertion of isoni

296 te electron transfer from chloride to the Ru metal center with rate constants in excess of 10(10) M(-

297 lar, those related to the interaction of the metal centers with the interstitial atom.

298 ones for a delicate geometric control at the metal center, with a network of weak interactions within

299 Spatial confinement of the metal center within a chiral pocket results in reversed

300 eavage processes occurring at the transition-metal center would facilitate the development of catalyt