ライフサイエンスコーパス: metal ion

1 outer-sphere coordination of O6 on G379 to a metal ion.

2 al coordination of the oxo atom donor to the metal ion.

3 mation stored by interaction with a specific metal ion.

4 ng energy that is sensitive to the choice of metal ion.

5 tranded DNA and requires only redox-inactive metal ions.

6 ation about how a storage protein loads with metal ions.

7 he coordination preference of the associated metal ions.

8 ticated systems to deal with the toxicity of metal ions.

9 cesses and catalysts based on Earth-abundant metal ions.

10 ing catalysts, such as the leaching of toxic metal ions.

11 oluble spherical nanoparticles with divalent metal ions.

12 ganic components plus coarse-mode transition metal ions.

13 3.0mLmin(-1) was selected as optimum for all metal ions.

14 Hg(2+) ions surprisingly well over 22 other metal ions.

15 aqueous silver nanoparticles toward divalent metal ions.

16 rganic strands enclosing a central column of metal ions.

17 f lead (cationic) and chromium(VI) (anionic) metal ions.

18 arious alkali, alkaline earth and transition metal ions.

19 membrane surface in the presence of divalent metal ions.

20 the polymeric particle shape with light and metal ions.

21 ll, k-turns become folded in the presence of metal ions.

22 s a specific sensor region and does not bind metal ions.

23 els, no size dependence for the other alkali metal ions.

24 hat SilE is a molecular sponge for absorbing metal ions.

25 s and ligands, including small molecules and metal ions.

26 y highly conserved acidic residues that bind metal ions.

27 ange of ligands, including haem, flavins and metal ions.

28 esence of other interfering biomolecules and metal ions.

29 regulated allosterically via the binding of metal ions.

30 by mutating only five residues and using two metal ions.

31 se fibrils, which we interpret as ladders of metal ions.

32 vacuolar pH, the presence of copigments, and metal ions.

33 impact on the extraction (and separation) of metal ions.

34 liable techniques for the detection of heavy metal ions.

35 ctive site required the presence of divalent metal ions, a free 5'-flap (if present), a Watson-Crick

36 ase domain, and identifying how the divalent metal ions affect the HNH domain conformational transiti

37 iently couples modular on-column immobilized metal ion affinity purification and solid-phase protein

38 lore the new theories for the predictions of metal ion and ligand binding sites and metal ion-depende

39 ided deeper insights into nature's choice of metal ion and reaction mechanism and allows for finer co

40 possessing a cuboidal framework made of 160 metal ions and a nanosized spherical cavity in the cente

41 was improved with increasing proportions of metal ions and acylation.

42 ng the detection of small organic chemicals, metal ions and biomarkers.

43 in nature, especially when interacting with metal ions and co-pigments.

44 e deoxyribozymes do not require redox-active metal ions and function with a combination of Zn(2+) and

45 OFs, constructed by the designed assembly of metal ions and functional organic linkers, are an emergi

46 nic frameworks (MOFs) built with tetrahedral metal ions and imidazolates, offer permanent porosity an

47 Metabolites can react with metal ions and NADPH to oxidize DNA or participate in SN

48 vivo quantification of pH, concentrations of metal ions and other analytes, and physical parameters s

49 o specific structures that are stabilized by metal ions and other co-solutes in the cell's interior.

50 ce different hues in nature, especially with metal ions and other copigments assisting.

51 not fully understood, but interactions with metal ions and phenolic compounds are thought to play im

52 a remarkably selective affinity for certain metal ions and provide a framework for studying molecula

53 general, the enzyme was resistant to several metal ions and reagents.

54 rmer has good recognition selectivity toward metal ions and the latter possesses unique properties fo

55 Identification of the function of metal ions and the RNA moieties, particularly nucleobase

56 generally applied to detect other endogenous metal ions and thus contribute to deeper understanding o

57 most tightly bound Hg(2+) ion from all other metal ions, and a binding capacity that is >/=18 times t

58 potential donor ligands can coordinate with metal ions, and thus such compounds can be used for the

59 PP)] and distinct differences from the three metal ion AP superfamily monoesterase, from Escherichia

60 Metal ions are naturally retained by skeletal tissues in

61 Heavy metal ions are non-biodegradable and contaminate most of

62 Similarly, two metal ions are required for proofreading; one helps to l

63 mily of calcium-dependent enzymes, where the metal ions are shown critical for their enzymatic activi

64 e two carboxylates that are affixed to the A metal ion as well as the non-bridging oxygen atoms of th

65 onstrates the potential for using a range of metal ions, as biocidal formulations against both plankt

66 te receptors; as ligands to coordinate large metal ions; as nonlinear optical materials, MRI contrast

67 resence of porphyrinoids containing the same metal ion at different oxidation states.

68 n compared to other environmentally relevant metal ions at concentration ratio more than 1000 times.

69 protectin (a host protein known to sequester metal ions at infectious foci) recapitulates responses o

70 ed as negative electrode material for alkali-metal-ion batteries, similar to its oxide analogue FeO.

71 s) are interesting as one of the alternative metal-ion battery systems to lithium-ion batteries (LIBs

72 This study of the roles of nonheme metal ions beyond the Cu and Fe found in native enzymes

73 f the channel which is responsible for tonic metal ion binding and which particularly distinguishes t

74 in endocytosis, extracellular exosomes, and metal ion binding are differentially expressed in cuticu

75 ation of catalytically inactive species upon metal ion binding.

76 driving force for founding the distinct one-metal-ion branch that contains all known AP superfamily

77 acks a conserved serine that anchors a water-metal ion bridge that is critical for quinolone interact

78 nts in the gas phase by ALD to form an outer metal ion bridging group, which can bind a second phosph

79 ACs contain metal ions but not organic cofactors, and use ATP to act

80 e of the trimeric BACE1 TMS is accessible to metal ions, but copper ions did not trigger trimerizatio

81 recedented double concave encapsulation of a metal ion by two bowl-shaped sumanenyl anions in [Cs(C21

82 neous determination of trace levels of heavy metal ions by anodic stripping voltammetry (ASV).

83 sites allows for the adaptation to different metal ions by constitutional variation.

84 erial RNase P propose direct coordination of metal ions by the nucleobases of conserved uridine and g

85 t not all, of the effects of these different metal ions can be rationalized based on their intrinsic

86 Hs) with one to five aromatic rings, and the metal ions Cd(II), Cr(III), Pb(II), and Pb(IV).

87 on and preconcentration method of some heavy metal ions, Cd(II), Cu(II), Ni(II), Pb(II) and Zn(II) at

88 concerted proton-electron transfer steps on metal-ion centres at their surface and product oxygen mo

89 ications typically rely on using traditional metal ion chelate or prosthetic group chemistries.

90 The small molecule metal ion chelators bipyridine and terpyridine complexed

91 ongs to the thiosemicarbazone (TSC) class of metal ion chelators that bind iron, copper, magnesium, z

92 te for coordination with the iPGM transition metal ion cluster.

93 the short-range structure is not random but metal ions cluster, forming percolation channels through

94 n both single and mixed alkali compositions, metal ion clustering and percolation radically affect me

95 nctional sites/groups can be introduced into metal ions/clusters, organic linkers, or pore spaces thr

96 y and representing most of the Earth magmas, metal ions compensate the electrical charge deficit of A

97 Regulation of enzymes through metal ion complexation is widespread in biology and unde

98 of cyclic polyethers and evaluation of their metal ion complexation properties.

99 ltammetry enabled the prediction of the free metal ion concentration within an order of magnitude for

100 n developed using models to predict the free metal ion concentration, the most ecologically relevant

101 Quantum mechanical studies of metal ion-containing systems at the semiempirical, ab in

102 uantum and classical modeling strategies for metal ion-containing systems that have been developed ov

103 ll further enhance the classical modeling of metal ion-containing systems.

104 The use of ICP-MS to measure metal ion content in biological tissues offers a highly

105 Through spatial control of metal ion content, we created a continuous mechanical gr

106 11 cys116, which is a functionally critical, metal ion-coordinating residue within a novel viral inte

107 this study, we analyze how mutation of four metal ion-coordinating residues of Arabidopsis thaliana

108 Nle1, and the interaction is dependent upon metal ion coordination because removal of the metal or m

109 provides evidence for inner-sphere divalent metal ion coordination with a nucleobase.

110 terms of their synthesis, characterization, metal ion coordination, and anion-recognition properties

111 ructures of charged metallacages obtained by metal ion coordination-driven solution self-assembly is

112 al phosphodiesterase that combines a ligated metal ion (Cu(II), Zn(II)) with a guanidinium unit conne

113 tion in ethylene biosynthesis and signaling, metal ions deficiency response, and root development rel

114 t interactions of the P4 helix of P RNA with metal ions, demonstrating that the bulged uridine coordi

115 The crystal structure of the metal-ion dependent esterase MGS0169 from the amidohydro

116 Midasin contains a C-terminal metal ion-dependent adhesion site (MIDAS) domain that in

117 nd mutation of residues within the conserved metal ion-dependent adhesion site motif impaired the abi

118 Simvastatin targets the metal ion-dependent adhesion site of the open, ligand-bi

119 t CLCA1-TMEM16A interactions are Mg(2+)- and metal ion-dependent adhesion site-dependent.

120 ns of metal ion and ligand binding sites and metal ion-dependent RNA stabilities.

121 alpha7-helixes work in concert to shift the metal-ion-dependent adhesion site between the resting an

122 e the active DNAzyme, which then carries out metal-ion-dependent cleavage, resulting in releasing the

123 Metal ion detection is critical in a variety of areas.

124 ers a summary of FNA- and nanomaterial-based metal ion detection methods.

125 DNAzymes are a promising platform for metal ion detection, and a few DNAzyme-based sensors hav

126 ging and promising diagnostic tool for heavy metal ions detection.

127 inciple into the field of self-powered heavy-metal-ion detection and removal using the triboelectrifi

128 or mutation of residues that coordinate the metal ion diminishes the interaction.

129 ows high sensitivities for the detections of metal ion, dopamine and single-stranded DNA (ssDNA), wit

130 nterface of NCs can be tuned and promoted by metal ion doping.

131 ultiple oligomeric states in the presence of metal ions, e.g. Fe(2+) and Co(2+), led to the suggestio

132 conductive additives and were often based on metal-ion electrolytes containing Li(+) or Na(+).

133 tions which pointed different approach of 5f metal ions electroreduction unlike 4p metal ions such as

134 chelating agents capable of sequestering the metal ion engines and thereby suppressing the catalytic

135 y by the identity of the divalent transition-metal ion (Fe(2+) or Ni(2+)) in the active site.

136 s higher chelating capacity of pro-oxidative metal ions (Fe(2+)), whereas the distribution pattern of

137 We used transition metal ion fluorescence resonance energy transfer experim

138 role of the newly discovered third divalent metal ion for DNA polymerase-catalyzed nucleotide incorp

139 hey typically recruit divalent and trivalent metal ions for catalysis.

140 recently, strategies that forego transition metal ions for p-block elements have emerged.

141 peptide, and/or an amino acid and a divalent metal ion (for 16 different monosaccharide isomers) are

142 Here, we used transition metal ion FRET and patch clamp fluorometry with a fluore

143 Combining transition metal ion FRET, patch-clamp fluorometry, and incorporati

144 r examined at pilot scale for the removal of metal ions from contaminated water.

145 tch for opening the channel and transferring metal ions from CusB to CusC and out of the cell.

146 While DPA displayed a propensity to chelate metal ions from NDM-1, 36 formed a stable NDM-1:Zn(II):i

147 inciple, this allows one to recover precious metal ions from solution in their metallic form, which a

148 ed by chaperone proteins, which scavenge the metal ions from the cytoplasm.

149 reover, Trm10 does not depend on a catalytic metal ion, further distinguishing it from the other know

150 ral prearrangement to coordinate one or more metal ions has been outlined.

151 y selective and high affinity recognition of metal ions, have been demonstrated.

152 d the acidic Asp side chain coordinates to a metal ion held by the beta3-subunit.

153 c solid, is highly amenable to host divalent metal ions, i.e., Mg(2+) and Ca(2+), in aqueous electrol

154 ing the surface chemistry change of NPSi and metal ions immersed-NPSi using XPS characterization.

155 ietary absorption of phosphate and essential metal ions, important for agriculture and with potential

156 The metal ion in the B site is coordinated by the same two c

157 The metal ion in the center of the DPP skeletons is strongly

158 omplex and observe a third transiently bound metal ion in the product state.

159 affected by the presence of small amounts of metal ions in aqueous solution in different ways.

160 panded the DNAzyme versatility for detecting metal ions in biological systems under NIR light that ex

161 ibute to deeper understanding of the role of metal ions in biological systems.

162 he coordination flexibility of native CDs to metal ions in CD-based metal complexes and summarize the

163 phoryl transfer reactions using two divalent metal ions in the active site.

164 ocal increase of Cu(2+) and other ROS-active metal ions in the aggregates or as a downstream conseque

165 mate moieties to facilitate the chelation of metal ions in the catalytic center of target enzymes.

166 distributions and for predicting the fate of metal ions in the environment.

167 catalyst depends on the applied potential as metal ions in the film are oxidized before the onset of

168 o effectively face the challenge of modeling metal ions in the gas, aqueous, and solid phases.

169 ission spectrometry was applied to determine metal ions in the peel, pulp, and seed of Passiflora edu

170 n signals generated due to presence of heavy metal ions in the solution matrix like current, potentia

171 nd a consequence of the electron transfer of metal ions in their cage by reduction and oxidation proc

172 n cage having protein, capable of extracting metal ions in their cages and a consequence of the elect

173 rized by a high stability of the coordinated metal ions in their respective redox states and electric

174 etermination of trace amounts of the studied metal ions in various food and water samples and validat

175 separate actinide(III) from lanthanide(III) metal ions in view of the treatment of the accumulated r

176 molecular imaging probe for the detection of metal ions in vivo, but also provides a tool for spectro

177 made up of multiple different ligands and/or metals ions in order to obtain more complex systems with

178 cule junctions (M=Co, Ni, Cu, or Zn divalent metal ions), in which the current flows perpendicular to

179 s of the host is the withdrawal of essential metal ions, in particular iron, which leads to "nutritio

180 metastatic bone cancer, in which radioactive metal ions including (99m)Tc, (153)Sm, and (223)Ra are u

181 Other divalent metal ions including Ca(2+), Cd(2+), Zn(2+), Ni(2+), Co(

182 The identification of 15 different metal ions including different oxidation states Cr(3+)/C

183 sitive and selective discrimination of heavy metal ions, including lanthanide and actinide salts in a

184 light-activated TiO2 could be prepared from metal-ion incorporation, reduction of TiO2, non-metal do

185 e-based sensors have been reported to detect metal ions inside cells.

186 We report a metal/ion interaction induced p-i-n junction across slig

187 Therefore, the metal/ion interaction plays a role in determining the su

188 To biochemically probe the function of metal ion interactions, we substituted the universally c

189 Such metal/ion interactions establish a p-doped region near t

190 ications like catalysis and intercalation of metal ions into layered structures.

191 at in the absence of DNA, only one catalytic metal ion is accommodated in the active site.

192 e uncovered, and a transient third (product) metal ion is observed in the product state.

193 influence of ligands on the spin state of a metal ion is of central importance for bioinorganic chem

194 u transport into the cytoplasm such that the metal ion is only released to high-affinity Cu chaperone

195 t-driven formation of the WOC from dissolved metal ions is a key process because it is essential in b

196 When a large excess of divalent metal ions is absent, the charge is largely balanced by

197 rate on the concentrations of hydroxide and metal ions is approximately linear and quadratic, respec

198 oieties, particularly nucleobases, that bind metal ions is important in RNA catalysis.

199 With no metal ions, lambdamax and absorbance was greatest for cy

200 Interference study with other metal ions like lead, cadmium and copper showed a neglig

201 Binding of the second metal ion may be facilitated by conformational variabili

202 was used to record depth profiles of alkali metal ions (Me(+)) within thin SiO2 layers.

203 lutionary ancestor of the more efficient two-metal-ion mechanism found in enzymes.

204 In this work, we disclose a metal-ion-mediated strategy to assemble trimeric coiled-

205 The effects of chelation of metal ions (Mg(2+), Al(3+), Cr(3+), Fe(3+), and Ga(3+))

206 Typical transition metal ion Mn(2+) and lanthanide ion Yb(3+) are adopted a

207 This Review focuses on classical metal ion modeling based on unpolarized models (includin

208 s to be learned about the way in which bound metal ions modulate the response of electrosprayed prote

209 All PAHs and metal ions modulated the Abeta aggregation process.

210 t and beyond to the toxicological effects of metal ions more generally.

211 cular Dynamics simulations, demonstrate that metal ions nano-segregate into percolation channels, mak

212 tructure in the presence of DNA, the cognate metal ions Ni(II) and Co(II), or the noncognate metal io

213 techniques to visualize the distribution of metal ions non-invasively, in situ, quantitatively, in t

214 ural data have suggested that binding of the metal ion occludes access or egress of substrates.

215 ron oxidized halide species coordinated to a metal ion of possible relevance to reductive elimination

216 By varying the central metal ion of the polypyridyl complexes (Os, Ru, and Fe)

217 This method is based upon the retention of metal ions on a column packed with poly[N-(3-methyl-1H-i

218 as effect of protease inhibitors and chosen metal ions on the aminopeptidase activity were determine

219 ociation of a hydrophobic cavity of CDs with metal ions or various inorganic nanoparticles is a very

220 ains metal ions such as silver and copper or metal ion pairs namely, silver-copper (Janus bionanocage

221 ng on these metal ions (silver or copper) or metal ion pairs.

222 le cavities and can accommodate two or three metal ions per molecule.

223 Metal ions play essential roles in many aspects of biolo

224 Metal ions play significant roles in numerous fields inc

225 egions in the respiratory system, transition metal ions predominately in the upper regions and organi

226 work, we have systematically varied both the metal ions presented at the vertices of the ferritin nod

227 s of the organic moieties and binding of the metal ion product to C96, D99, and C159.

228 Additionally, the metal ions provide higher stability to the holo protein.

229 ) and MOF-1115(RE)] with variable rare earth metal ions (RE(3+) = Y(3+), Sm(3+), Eu(3+), Gd(3+), Tb(3

230 that the selective metal capture occurs in a metal ion recognition process somehow mimicking what hap

231 etching), and facilitates renal clearance of metal ions released from the quantum dots.

232 aken as a sustainable power source for heavy-metal-ion removal by recycling the kinetic energy from f

233 xo atom donor reactivity correlates with the metal ion's ability to bind exogenous ligands.

234 o weak to form isolable complexes due to the metal ion's limited capacity for pi-backdonation.

235 This is an enzyme with divalent metal ion(s) (Mg(2+) or Mn(2+)) in its catalytic site: c

236 ins, which may be involved in metal sensing, metal ion selectivity and/or in regulation of the pump a

237 lly, the challenges and future directions of metal ion sensors are presented.

238 DNAzymes have enjoyed success as metal ion sensors outside cells.

239 tnessed great progress in the development of metal ion sensors using functional nucleic acids (FNAs)

240 properties for enhancing the performance of metal ion sensors.

241 nses, coagulative activities, and transition metal ion sequestration, highlighting that the immune re

242 C-O coupling process in which the lanthanide metal ion serves as Lewis acid to activate the enol of t

243 Nanosized aggregations of metal ions shielded by organic ligands possessing both e

244 delocalization over the nanographene and the metal ion significantly decreases the electrical potenti

245 iting" and "erase" states depending on these metal ions (silver or copper) or metal ion pairs.

246 active at low pH in the absence of divalent metal ions, similar to eukaryotic DNase II.

247 s well as their interactions with membranes, metal ions, small molecules and engineered nanoparticles

248 The effects of metal ion solutions (silver, copper, platinum, gold and

249 Overall, platinum, palladium and gold metal ion solutions in individual use or combination dem

250 ing crystal violet biofilm assays for single metal ion solutions, antimicrobial efficacies were demon

251 ster ion for sputtering and a bismuth liquid metal ion source for analysis, both surfaces of leaves a

252 e reveals a delicate interplay through which metal ions stabilize the amyloid structure, which in tur

253 The metal ion strongly influences both kinetics and intermed

254 of 5f metal ions electroreduction unlike 4p metal ions such as As(III).

255 wn to have a strong tendency to complex with metal ions such as Fe(II) and Fe(III) in aquatic environ

256 emical biosensors for the detection of heavy metal ions such as Hg(2+), Ag(+), Cu(2+) and Pb(2+).

257 Protein substrate contains metal ions such as silver and copper or metal ion pairs

258 ractions with the solvent molecules or other metal ions, such as SrII.

259 and detection sensitivity in the presence of metal ions suggests that the developed nano-probes can b

260 oxide, for example, can intercalate hydrated metal ions that assemble into metal oxide films during t

261 ibited significant potential for the studied metal ions that can be further examined at pilot scale f

262 f a supramolecular system "Pt complex-alkali metal ion"; the latter is supported by restoration of th

263 ectrochemical detection techniques for heavy metal ions those are user friendly, low cost, provides o

264 d uridine coordinates at least one catalytic metal ion through an inner-sphere interaction.

265 rst nonhelical DNA structure driven by heavy-metal ions, thus further contributing to the structural

266 At the surface, transition metal ions (TM ions) are in a lower valence state than i

267 ographene to form a molecular complex with a metal ion to tackle this challenge.

268 This protein is also required to deliver the metal ion to the Cu/Zn superoxide dismutase SodCII.

269 ification or the recruitment of coenzymes or metal ions to achieve catalytic function.

270 onto aerosol liquid water and can react with metal ions to form stable metal-cyanide complexes.

271 tive catalase and/or redox-active transition metal ions to generate thiyl radicals that mediate compo

272 However, these methods required an influx of metal ions to increase their concentrations for detectio

273 H could increase to neutral which caused the metal ions to precipitate near completion.

274 family of trafficking molecules that provide metal ions to protein targets for use as cofactors.

275 ts, ranging from small organic molecules and metal ions to proteins and cells.

276 imperative to find environmentally-friendly metal ions to replace lead for the further development o

277 The use of metal ions to template the synthesis of catenanes by Sau

278 t posited preferential binding of transition metal ions to the outward-facing apo state of DAT and a

279 s within proteins is essential in catalysis, metal ion transport, and regulatory metallobiochemistry.

280 SLC39A8 encodes ZIP8, a divalent metal ion transporter best known for zinc transport.

281 transporters in the small intestine divalent metal-ion transporter 1 (DMT1) and ferroportin were not

282 ane of the intestinal enterocyte by divalent metal-ion transporter 1 (DMT1) and is exported into the

283 hod is widely applicable to studies of other metal ion transporters and metal-dependent processes in

284 tein (PrP) evolved from the subbranch of ZIP metal ion transporters comprising ZIPs 5, 6 and 10, rais

285 Using a series of engineered metal ion trapping mutants, we showed that the more comp

286 to H2O, but the exact mechanism the nonheme metal ion uses to confer and fine-tune the activity rema

287 romotors has been tuned by the choice of the metal ion utilized.

288 Transition-metal ions (V, Cr, Fe, Co, etc.) isolated on silica surf

289 ued, in which the enzyme's susceptibility to metal ions was exploited.

290 cognition behavior of FONs towards different metal ions was investigated with fluorescence spectrosco

291 The different valence states of tetrahedral metal ions were suggested to be responsible for the diff

292 s a variety of divalent first-row transition metal ions, which is implicated in its antimicrobial fun

293 ensitivity to silver ions (Ag(+)) over other metal ions with a detection limit of 0.25 muM in an aque

294 saturation transfer (PARACEST) in transition metal ions with long electronic relaxation times (taus)

295 es and surfaces of MoS2 can adsorb different metal ions with no need to ligand and functionalization.

296 The ability of complexes of hard and labile metal ions with one or more open coordination sites to c

297 indicating that the membrane can coordinate metal ions with the A' helix.

298 trends in electrochemical detection of heavy metal ions with various types of sensing platforms inclu

299 al ions Ni(II) and Co(II), or the noncognate metal ion Zn(II).

300 devoted to the binding site prediction of 13 metal ions (Zn(2+), Cu(2+), Fe(2+), Fe(3+), Ca(2+), Mg(2