ライフサイエンスコーパス: metal-free

1 colorless, rather unstable, and essentially metal-free.

2 Here, we report a one-step, regioselective, metal-free (18)F-labeling method that uses a hypervalent

3 A metal-free [2+2] cycloaddition and 1,4-addition sequence

4 However, the synthesis of a metal-free [2]rotaxane containing triazole with other fu

5 the position of the wheel on the axle of the metal-free [2]rotaxane.

6 lf-shielded (68)Ge/(68)Ga generator provided metal-free (68)GaCl3 ready for peptide labeling in the f

7 The resolved metal-free 819 knot enantiomers have pronounced features

8 an unexpectedly stable form, and produce a "metal-free" A-D-A (acceptor-donor-acceptor) oligomer emi

9 ultifunctional tool development against both metal-free Abeta and metal-Abeta.

10 -H oxygenation of aliphatic amines through a metal-free activation of molecular oxygen has been devel

11 phan and co-workers clearly implies that the metal-free activation of N2 with frustrated Lewis pairs

12 The method provides a simple, metal-free alternative for the synthesis of biologically

13 A metal-free aminoarylation of internal alkynes is describ

14 We report here on the first noble-metal free and covalent dye-catalyst assembly able to ac

15 ds for depicting the broader future of these metal-free and fully stable semiconductors.

16 tudies indicate that the compound ML targets metal-free and metal-bound Abeta (metal-Abeta) species,

17 Multifunctional molecules, which can target metal-free and metal-bound Abeta and modulate their reac

18 ity to mitigate the toxicity induced by both metal-free and metal-bound Abeta.

19 /-associated Abeta, and further control both metal-free and metal-induced Abeta aggregation was inves

20 synthesis of homopropargylic alcohols under metal-free and mild condition is described.

21 phenes with complete regioselectivity, under metal-free and mild conditions.

22 triflimide (HNTf2) at room temperature under metal-free and mild reaction conditions and leads with a

23 This precious metal-free and nontoxic photocatalytic system displays b

24 in good to excellent yields under transition-metal-free and peroxide-free conditions.

25 The transition-metal-free and temperature-dependent highly selective re

26 emicarbazone and its zinc complex as seminal metal-free and transition-metal-free examples.

27 drawn broad interdisciplinary attention as a metal-free and visible-light-responsive photocatalyst in

28 regulate the aggregation and cytotoxicity of metal-free and/or metal-associated Abeta to different ex

29 substrates, short reaction time, transition metal-free, and gram-scale synthesis are the advantages

30 A transition metal free approach for the synthesis of substituted phe

31 The development of a simple, transition-metal-free approach for the formation of phosphorus-phos

32 An efficient transition metal-free approach for the generation of N-unsubstitute

33 A metal-free approach for the synthesis of 3-aryl-2-substi

34 This transition-metal-free approach is high yielding, compatible with a

35 us catalyst and this solvent- and transition metal-free approach is unprecedent in the synthesis of n

36 An efficient, metal-free approach to 3-substituted 3-hydroxyoxindole b

37 A mild and metal-free approach to C-N coupling is described that em

38 We report a metal-free approach to reversible CO2 binding under mild

39 We have discovered a transition-metal-free approach to the synthesis of 2,2'-bis(naphtho

40 The protocol features a metal-free approach, broad substrate scope, very short r

41 In the past decade, metal-free approaches for C-C bond formation have attrac

42 Remarkably, this metal-free aromatic C-H activation occurs at room temper

43 A transition-metal-free arylation of lithium, magnesium, and zinc sul

44 to determine the effect of counter anions in metal-free arylation reactions of diaryliodonium salts i

45 recently attracted significant attention as metal-free-arylation reagents in organic synthesis, and

46 se compounds to interact with metal ions and metal-free/-associated Abeta, and further control both m

47 Photoinduced metal-free atom transfer radical polymerization (ATRP) o

48 r understanding of the chemical processes of metal-free ATRP that can aid the design of better cataly

49 n mechanism is proposed for the tribofilm of metal-free AW additives, including direct tribochemical

50 etal-bound complex of the azirinium ylide to metal-free azirinium ylide, ring-opening of the latter t

51 y and selectivity of unprotected azadiene in metal-free base-assisted hetero-Diels-Alder reaction is

52 The pyrolyzed MPSA/GO acted as the first metal-free bifunctional catalyst with high activities fo

53 terocyclic terminal groups indicate that the metal-free bipyridyl group, not other features of the ju

54 manner, we present, among others, the first metal-free borylene(I) species containing a nitrogen-bas

55 An efficient, catalyst-free, and metal-free bromoamidation of unactivated olefins has bee

56 A transition-metal-free C-3-arylation of quinolin-4-ones in the prese

57 ave the way for new approaches to transition-metal-free C-C bond formations.

58 A light induced, transition-metal-free C-C coupling reaction of 2-chlorobenzazoles w

59 I-TBHP combination which efficiently induces metal-free C-H activation of aldehydes under neat condit

60 Further, a direct metal-free C-H functionalization (azidation, alkoxylatio

61 nal and experimental studies reveal that the metal-free C-H insertion proceeds via a frustrated Lewis

62 foxidation, herein, we discovered a mild and metal-free C-H sulfenylation/intramolecular rearrangemen

63 here are unprecedented in other contemporary metal-free C-N coupling reactions.

64 t nucleophiles for performing regioselective metal-free C-O and C-N bond-cleaving to afford prevalent

65 rigin facilitate the development of advanced metal-free carbocatalysts for a wide range of electrocat

66 properties of a new generation of transition-metal-free carbon monoxide-releasing molecules based on

67 compounds has emerged recently as a powerful metal-free carbon-carbon bond forming method.

68 ogress in the fabrication and application of metal-free carbonaceous materials as photo- or electroca

69 Metal-free carbonaceous materials, including nitrogen-do

70 This reactivity provides a strategy for metal-free catalysis of olefin hydrogenations.

71 findings will also open new possibilities in metal-free catalysis or organic crystal engineering, whe

72 a powerful tool for further developments in metal-free catalysis.

73 emerged recently as useful electrophiles in metal-free catalysis.

74 sformative in small molecule activations and metal-free catalysis.

75 le Co NPs are a promising new class of noble-metal-free catalyst for water splitting.

76 Porous graphene oxide can be used as a metal-free catalyst in the presence of air for oxidative

77 The trifunctional metal-free catalyst was further used as an OER-HER bifun

78 P, and F tri-doped graphene multifunctional metal-free catalyst, can operate in ambient air with a h

79 ctionalities are tolerated by the transition metal-free catalyst.

80 airs' (FLPs) have been shown to be effective metal-free catalysts for the hydrogenation of many unsat

81 progress in the development of carbon-based metal-free catalysts for the OER and HER, along with cha

82 xygen reduction reaction (ORR), carbon-based metal-free catalysts have also been demonstrated to be p

83 ress has been made toward the development of metal-free catalysts of enantioselective transformations

84 the possibility to use stable platinum-group-metal-free catalysts, with inherent, long-term cost adva

85 materials have attracted growing interest as metal-free catalysts.

86 carbon-based non-noble metal catalysts, and metal-free catalysts.

87 catalysts for this reaction, but developing metal free catalytic systems would lead to highly desira

88 shell phenalenyl chemistry toward transition metal-free catalytic C-H functionalization process.

89 vered unique stoichiometric transformations, metal-free catalytic hydroamination, CO2 reduction chemi

90 st decade has seen the subject of transition metal-free catalytic hydrogenation develop incredibly ra

91 substrates, including the first examples of metal-free catalytic hydrogenation of furan heterocycles

92 This allows metal-free catalytic hydrogenations to be performed in d

93 systems are expected to provide an efficient metal-free catalytic preparation of functional polymers.

94 A metal-free CH-CH-type coupling of arenes and alkynes, me

95 include mild reaction conditions, the heavy-metal-free characteristic of the oxidative coupling proc

96 Transition-metal-free chemo- and stereoselective addition of 5-amin

97 Transition-metal-free chemo-, regio-, and stereoselective synthesis

98 We report the synthesis of a metal-free chemosensor for highly selective sensing of p

99 which provides an unprecedented protocol for metal-free CO2 conversion.

100 OA) as sacrificial electron donor, the noble-metal-free complex Ni4P2 works as an efficient and robus

101 l emphasis on earth-abundant and toxic heavy metal free compounds.

102 Many transition-metal complexes and some metal-free compounds are able to bind carbon monoxide, a

103 nyl-3-alkyl/aryl 2-oxindole under transition-metal free condition.

104 l- and alkynylboronic acids under transition-metal-free conditions are beginning to emerge.

105 es with aryl alkyl ketones under oxidant and metal-free conditions are described.

106 ted imidazopyridines has been achieved under metal-free conditions at room temperature in short react

107 cetic acids into aryl carboxylic acids under metal-free conditions has been described.

108 s and potassium organotrifluoroborates under metal-free conditions has been developed.

109 (3))-H functionalization of enaminones under metal-free conditions has been developed.

110 ir respective sulfonyl chlorides under mild, metal-free conditions leading to efficient atom transfer

111 3))-C(sp(2)) bond formation under transition-metal-free conditions offers an atom-economical, inexpen

112 Mild, metal-free conditions were successfully applied to produ

113 beta-position of styrenes was achieved under metal-free conditions.

114 yst (S)-3,3'-F2-BINOL under solvent-free and metal-free conditions.

115 copolymerization of epoxides with CO2, under metal-free conditions.

116 reaction could be synthesized under mild and metal-free conditions.

117 a(5)-phosphaquinolin-2-ones under transition-metal-free conditions.

118 the cleavage of a C-C bond under transition-metal-free conditions.

119 g sustainable routes under template-free and metal-free conditions.

120 ervalent diaryliodonium salts under mild and metal-free conditions.

121 cess to 2-aroylbenzoxazoles under transition-metal-free conditions.

122 cleave the customizable Hyp unit under mild, metal-free conditions.

123 yanation of benzyl cyanides in one pot under metal-free conditions.

124 uantitative yields of desired products under metal-free conditions.

125 ed SRN1 mechanism under mild and "transition-metal-free" conditions.

126 This method is ideal for the metal-free construction of heterocycle-containing drug t

127 methyl group in the complexes than in their metal-free counterparts.

128 roteins are markedly more compact than their metal-free counterparts.

129 ures the first application of the transition-metal-free coupling of a tosyl hydrazone and a boronic a

130 the initiation of very efficient transition-metal-free coupling of haloarenes to arenes.

131 We report an unprecedented transition metal-free coupling of indoles with aryl halides.

132 al impurities has brought a renewed focus on metal-free coupling processes.

133 Transition metal-free couplings of haloarenes with arenes, triggere

134 This is the first transition-metal-free cross-coupling of azaallyls with vinyl bromid

135 An operationally simple and metal-free cross-coupling of quinone monoacetals (QMAs)

136 A metal-free cross-dehydrogenative coupling between quinox

137 A metal-free cross-dehydrogenative coupling method for the

138 hloride (FeTPP) catalyst by colloidal, heavy metal-free CuInS2/ZnS quantum dots (QDs) to reduce CO2 t

139 -substituted piperidine-2-carboxamides via a metal-free decarboxylative multicomponent coupling betwe

140 traditional strategies, we report a one-pot metal-free decarboxylative procedure for accessing beta,

141 pre-organized Si-B separation in 1 enables a metal-free dehydrogenation of H2 O to give the silanone-

142 amino acids at the ligation points following metal-free dethiylation.

143 The synthesis involved a recently reported metal-free direct benzylation between tosylhydrazone and

144 The AP probes are metal-free, easily synthesizable, non-toxic, thermally s

145 ost, highly active, durable completely noble metal-free electro-catalyst for oxygen reduction reactio

146 The identified novel noble metal-free electro-catalyst showed similar onset potenti

147 es and perspectives in the emerging field of metal-free electrocatalysis.

148 Ss) in carbon enables the synthesis of noble-metal-free electrocatalysts for clean energy conversion

149 d mesoporous carbons can serve as efficient, metal-free electrocatalysts for hydrazine oxidation reac

150 An overview of the defects in carbon-based, metal-free electrocatalysts for ORR and various defects

151 arbon nanomaterials have proven to be robust metal-free electrocatalysts for ORR in the above-mention

152 olybdenum sulfides are very attractive noble-metal-free electrocatalysts for the hydrogen evolution r

153 Metal-free electrocatalysts have been extensively develo

154 complex as seminal metal-free and transition-metal-free examples.

155 Overall, this metal-free formal [2 + 2 + 2] cycloaddition provides acc

156 Metal-free, formal [2 + 2 + 2] cycloaddition strategies

157 good to excellent yields in a multicatalytic metal-free, four-step one-pot cascade reaction under mil

158 estigates design strategies than can lead to metal free frustrated Lewis pairs (FLPs) that can be emp

159 benzoylation and alkenylation protocols are metal-free, green, simple, efficient, and tolerate a wid

160 dily delivered to an empty catalytic site of metal-free HAO via an intermolecular transfer mechanism.

161 The development of noble-metal-free heterogeneous catalysts that can realize the

162 m marine waste and its use demonstrated in a metal-free heterogeneous selective oxidation of 5-hydrox

163 A metal-free highly diastereoselctive [3 + 2] cycloadditio

164 of metal-bound His is different from that of metal-free His.

165 te solar cells (PSC) are manufactured with a metal-free hole contact based on press-transferred singl

166 s contribution we report about light-induced metal-free homocoupling of terminal alkynes on highly or

167 de with nitrogen-doped graphene to produce a metal-free hybrid catalyst, which shows an unexpected hy

168 ne-step facile synthesis of a novel precious-metal-free hydrogen-evolution nanoelectrocatalyst, dubbe

169 derable momentum into the area of transition-metal-free hydrogenation and, likewise, hydrosilylation.

170 In addition, effective stereoselective metal-free hydrogenation catalysts have begun to emerge.

171 a low-cost, high-performance platinum-group-metal-free hydroxide exchange membrane fuel cell is hind

172 ves that self-react to grow a tribofilm, the metal-free ILs require a supplier of metal cations in th

173 The use of metal-free, inexpensive redox-active organic materials r

174 A transition-metal-free, K2S2O8-mediated intramolecular oxidative nit

175 A rapid, efficient, and metal-free Lewis acid-mediated methodology has been deve

176 on of carbonyl sulfide (COS) and epoxides by metal-free Lewis pair catalysts composed of a Lewis base

177 A metal-free, Lewis acid promoted intramolecular aminocyan

178 and a candidate cathode material for lithium-metal-free Li-S cells.

179 benefits of this reaction include the use of metal-free, low-cost Rose Bengal catalyst and practical

180 The quest for a novel low-dimensional metal-free magnetic material that would exhibit magnetis

181 e adsorption free energy of intermediates on metal-free materials, similarly as in the case of metall

182 We report the facile and efficient metal-free metathesis reaction of C-chiral allylic sulfi

183 This noble-metal-free method complements alternative methods that a

184 A novel, scalable, and metal-free method for accessing a wide range of fluorina

185 A versatile, efficient, and metal-free method for construction of discrete oligomers

186 This method demonstrates the first metal-free method for controlled ROMP.

187 A metal-free method for fast and clean anilide formation f

188 tho-EMe (E=S, O) groups represents a simple, metal-free method for the formation of C3-borylated benz

189 An efficient metal-free method for the synthesis of alpha-ketothioest

190 Herein, we report a simple and metal-free method for the synthesis of N-azine sulfoximi

191 This transition-metal-free method provides a straightforward entry to st

192 A novel transition-metal-free method to construct N-hydroxy oxindoles by an

193 This metal-free method was used for the catalytic formation o

194 ture prominently in both metal-catalyzed and metal-free methodologies for the formation of B-C bonds

195 Herein, we report a solvent- and metal-free methodology for the alkoxy-chalcogenylation o

196 that currently pose a challenge to classical metal-free methods are accommodated and the alicyclic am

197 review lies on more recent and in some cases metal-free methods for epoxide polymerization, i.e., the

198 otoinduced cycloaddition was performed under metal-free, mild conditions allowing the preparation of

199 A new transition-metal-free mode for the catalytic reduction of carbon di

200 We describe here the first metal-free multicomponent approach to conjugated polymer

201 oron-doped graphene quantum dot (B-GQD) as a metal-free multimodal contrast agent (CA) for safe magne

202 recent advances in the development of heavy-metal-free nanocrystals within the context of specific p

203 Metal-free near-infrared (NIR) active unsymmetrical squa

204 acile one-electron oxidation to the acyclic, metal-free, neutral radical L(.) on reaction with FeBr2

205 Finally, the mild and metal-free new access to aminobiphenyls was shown to be

206 .1%, the highest value achieved so far by a "metal-free" NIR-OLED not intentionally benefitting from

207 Novel zinc, magnesium, and metal-free octasubstituted phthalocyanine photosensitize

208 A metal-free one step coupling reaction between various N-

209 A general and efficient method for a metal-free one-pot synthesis of highly substituted fused

210 able inexpensive substrates, simplicity of a metal-free one-pot synthesis, and ease of scale-up to mu

211 An operationally simple, metal-free, one-pot synthetic procedure involves the ini

212 zoxazoles toward various nucleophiles, under metal-free or iron-catalyzed conditions, for the synthes

213 A new series of metal-free organic chromophores (TPA-TTAR-A (1), TPA-T-T

214 eved, among the highest reported to date for metal-free organic DSSC sensitizers using an I(-)/I3(-)

215 Three new metal-free organic dyes with the [1]benzothieno[3,2-b]be

216 reatly enhance phosphorescence efficiency of metal-free organic materials in a variety of amorphous p

217 The design and preparation of metal-free organic materials that exhibit room-temperatu

218 Metal-free organic phosphorescent materials are attracti

219 from methyl cholate through a combination of metal-free organo-catalytic living ring-opening polymeri

220 nosilicon compounds, dibromoboranes, and the metal-free organocatalyst Me3SiNTf2.

221 djacent stereogenic centres and a transition metal-free organocatalytic asymmetric approach to beta-a

222 derived N-doped carbon material is promising metal-free ORR catalyst for fuel cells and capacitor ele

223 anil/H(+) reagent as the recyclable organic (metal-free) oxidant system to afford benzidines/naphthid

224 nd chemoselective methods for the transition-metal-free oxidation of amides to alpha-keto amides and

225 In this new metal-free oxidation system (Na2S2O4/TBHP), SO4(.-) can

226 n, 1,3-dipolar cycloaddition, and transition metal-free oxidative aromatization reaction sequence uti

227 The reaction is initiated by a metal-free oxidative coupling of primary alkoxides and d

228 A facile transition-metal-free oxidative cross-dehydrogenative coupling reac

229 Metal-free, p-toluenesulfonic acid (p-TSA)-mediated, str

230 (pinBC identical withCBpin) ligands and also metal-free perborylated C1 and C2 products, such as C(Bp

231 Platinum group metal-free (PGM-free) metal-nitrogen-carbon catalysts ha

232 e ability to tune the reduction potential of metal-free phenothiazine-based photoredox catalysts and

233 and prospects for the future development of metal-free photo- and electrocatalysts.

234 s work introduces a new class of air-stable, metal-free photo-redox reagents capable of mediating che

235 A metal-free photoanode nanojunction architecture, compose

236 can serve as efficient and robust, precious-metal free, photoassisted redox catalysts.

237 ds under mild conditions: a combination of a metal-free photocatalyst, a chain-transfer agent, and li

238 Hydrogen generation from water using noble metal-free photocatalysts presents a promising platform

239 f 1.4% was recorded for the noble- and toxic-metal free photocatalytic system.

240 We describe a metal-free, photocatalytic hydrodefluorination (HDF) of

241 We report herein a simple, additive- and metal-free, photoinduced, dual C-H/C-X borylation of chl

242 ith visible light, leading to a new class of metal-free photooxidants.

243 thesized and introduced as strongly reducing metal-free photoredox catalysts in organocatalyzed atom

244 the molecular ordering in solution-processed metal-free phthalocyanine crystalline thin films with ma

245 d for hexadeca-cationic zinc, magnesium, and metal-free phthalocyanines (Pcs) and tetrapyrazinoporphy

246 ce as a highly active photocatalyst, and the metal-free polymer was shown to be able to generate hydr

247 The metal-free polymerization of propylene oxide (PO) using

248 We demonstrate that a series of metal-free porphyrins can drive photoelectrochemical wat

249 thiol-ene chemistry allows for a completely metal-free preparation of cross-linked polyDCPD.

250 CH-CH coupling are highly versatile, and the metal-free process can be used for the construction and

251 This noble metal-free process follows a nature-inspired pathway of

252 A visible light mediated, metal-free process for the thiocyanation of imidazoheter

253 catalyst, which results in fully transition-metal-free processes.

254 A transition-metal-free protocol for the redox-neutral light-induced

255 A general and practical metal-free protocol for the synthesis of 1,2-dihydropyri

256 ationally simple, and single-step transition-metal-free protocol for the synthesis of enantiomericall

257 f a recently reported, highly chemoselective metal-free protocol of wide general applicability for th

258 The present one-pot transition-metal-free protocol provides the facile and highly effic

259 A metal-free protocol to generate phthalimide-N-oxyl (PINO

260 This metal-free protocol was applied to different cyclic alke

261 ng and a pendent free-NH2 moiety, features a metal-free protocol, mild reaction conditions, simple wo

262 permeable polystyrene cores crosslinked with metal-free purely organic phosphors.

263 ve amidation of aldehydes and alcohols via a metal-free radial pathway has been demonstrated.

264 n with the stronger oxidant AgBF4 formed the metal-free radical dication L(.2+) .

265 This metal-free reaction can be easily carried out at room te

266 2]-annulation is operationally simple under metal-free reaction conditions with 100% atom economy an

267 ) and dimethyl sulfoxide as an oxidant under metal-free reaction conditions.

268 This metal-free reaction is operationally simple, proceeds at

269 The transition-metal-free reaction proceeds in a regio- and stereoselec

270 actone (gamma-BL) to a high-molecular-weight metal-free recyclable polyester is reported.

271 establish an alternative class of sensitive, metal-free reporter genes for non-invasive imaging.

272 Metal-free ring-opening metathesis polymerization (ROMP)

273 trates new monomers that can be utilized for metal-free ROMP.

274 ctures of the excited triplet states for the metal-free room-temperature triplet emitters are correla

275 In the metal-free rotaxane, there is rapid singlet excitation e

276 A transition-metal-free route for the synthesis of several N-fused he

277 nanoporous carbons (NOSCs) that can serve as metal-free, selective electrocatalysts and catalysts for

278 This transition-metal-free sequential synthesis process is compatible wi

279 Abundant and environmentally benign metal-free silicon-based reagents, including chloride su

280 We describe a metal-free small molecule catalyst that achieves the thr

281 We offer a mild, metal-free sp(3) C-H fluorination alternative using Sele

282 A novel class of metal-free spherical nucleic acid nanostructures was syn

283 The methodology has the advantages of a metal-free strategy, easy to handle reagents, functional

284 as valuable substrates for the photoinduced metal-free synthesis of (hetero)biaryls with no need of

285 A facile metal-free synthesis of 2-aminothiophene derivatives by

286 This report represents a novel and metal-free synthesis of 3,3'-bisimidazopyridinylmethanes

287 gh yield solvent-base-controlled, transition metal-free synthesis of 4,5-functionalized 1,2,3-thiadia

288 A mild and metal-free synthesis of aryl isocyanates from arylamines

289 A mild and transition-metal-free synthesis of beta-keto arylthioethers has bee

290 ON>2000), which renders this the most active metal-free system for the polymerization of PO reported

291 This metal-free system was convenient, practical, and insensi

292 Exploring this concept with a metal-free system, we have synthesized a pyridine-coordi

293 er s-, p-, d-, and f-block metals as well as metal-free systems has been revealed.

294 ere 2-20 times faster than those observed in metal-free systems.

295 A successive metal-free TBHP-mediated regioselective C-H functionaliz

296 A transition-metal-free, three-component coupling involving N-substit

297 ting from the far-red to deep-blue region in metal-free triplet-triplet annihilation upconversion (TT

298 Metal-free, visible light-initiated, living cationic pol

299 Here we demonstrate self-mending in metal-free water of synthetic polyacrylate and polymetha

300 eriod, followed by depuration for 2 weeks in metal-free water using live-animal gamma-spectrometry.