ライフサイエンスコーパス: metaphase plate

1 they failed to align the chromosomes into a metaphase plate.

2 r microtubule capture nor congression to the metaphase plate.

3 eased staining on chromosomes aligned at the metaphase plate.

4 ion until all chromosomes are aligned at the metaphase plate.

5 set until all chromosomes are aligned at the metaphase plate.

6 before the chromosomes had assembled at the metaphase plate.

7 ces, drive congression of chromosomes to the metaphase plate.

8 essential for positioning chromosomes at the metaphase plate.

9 separate and the X chromosomes remain at the metaphase plate.

10 r spindle with chromosomes aligned along the metaphase plate.

11 or (2) the absence of oscillations about the metaphase plate.

12 a3 mutant cannot position chromosomes at the metaphase plate.

13 correct alignment of all chromosomes at the metaphase plate.

14 they are able to congress chromosomes to the metaphase plate.

15 until all chromosomes are bioriented on the metaphase plate.

16 olar microtubule attachment and align at the metaphase plate.

17 tids until chromosomes become aligned at the metaphase plate.

18 essential for positioning chromosomes at the metaphase plate.

19 et until all kinetochores are aligned on the metaphase plate.

20 ients and aligns sister chromatids along the metaphase plate.

21 s growing from acentrosomal poles toward the metaphase plate.

22 urrow, and realignment of chromosomes at the metaphase plate.

23 in defects in chromosome congression at the metaphase plate.

24 es and the congression of chromosomes to the metaphase plate.

25 ntil chromosomes are properly aligned on the metaphase plate.

26 nse as well as directing the assembly of the metaphase plate.

27 roteins maintain their associations with the metaphase plate.

28 "flares" that project out laterally from the metaphase plate.

29 until all the chromosomes are aligned at the metaphase plate.

30 the chromosomes are aligned properly at the metaphase plate.

31 are unable to align their chromosomes at the metaphase plate.

32 eiosis if chromosomes are not aligned at the metaphase plate.

33 es of the last chromosome to congress to the metaphase plate.

34 activated after chromosome alignment at the metaphase plate.

35 feres with congression of chromosomes to the metaphase plate.

36 ic chromosomes that have not yet reached the metaphase plate.

37 chromosomes, and their eventual alignment on metaphase plates.

38 ex, followed by cleavage in the plane of the metaphase plate [1, 2].

39 34A impairs mitotic progression by affecting metaphase plate alignment and pressure generation by del

40 , PLK-1-dependent chromosome congression and metaphase plate alignment are necessary for the disassem

41 ciated with failures in establishing a tight metaphase plate and an increase in anaphase lagging chro

42 nst human SMC1 led to disorganization of the metaphase plate and cell cycle arrest, indicating that h

43 y condensed chromosomes were not arranged on metaphase plate and chromosomal perturbations were obser

44 matids allows chromosomes to biorient on the metaphase plate and holds them together until they separ

45 show defects in chromosome alignment at the metaphase plate and in spindle pole integrity.

46 ese factors chromosomes fail to align at the metaphase plate and kinetochores do not orient to opposi

47 elongated chromosomes that extended off the metaphase plate and outside the perimeter of the spindle

48 defective congression of chromosomes to the metaphase plate and persistent activation of the spindle

49 Accumulation of SUMO conjugates on the metaphase plate and proper chromosome alignment depend o

50 needles were inserted on either side of the metaphase plate and rapidly moved apart, there was minim

51 the proper orientation of chromosomes at the metaphase plate and their subsequent disjunction during

52 ibutes both to chromosome congression to the metaphase plate and to the coupling of spindle microtubu

53 of binucleated cells and displayed abnormal metaphase plates and anaphase chromatin bridges suggesti

54 for chromosome congression to a well ordered metaphase plate, and for timely initiation of anaphase.

55 , does not block chromosome alignment at the metaphase plate, and is not detected by the spindle chec

56 f temperature shift, bivalents moved off the metaphase plate, and microtubule bundles within the spin

57 aphase, timely chromosome congression to the metaphase plate, and proper interkinetochore tension for

58 oper centromere motility, congression to the metaphase plate, and subsequent anaphase chromosome segr

59 h spindle poles, chromosomes congress to the metaphase plate, and the tension between kinetochores an

60 ive chromosomal positions on each individual metaphase plate are most likely carried through anaphase

61 Metaphase plates become thinner as cells progress toward

62 rs to be dependent on the position along the metaphase plate, both types of behavior are observed wit

63 Chromosomes aligned normally on the metaphase plate but were unable to segregate.

64 Inactivation of the checkpoint prior to metaphase plate centering leads to asymmetric cell divis

65 Normally, within minutes of alignment at the metaphase plate, chromatid cohesion is released, allowin

66 ired for the alignment of chromosomes at the metaphase plate (chromosome congression).

67 , some chromosomes failed to congress to the metaphase plate, consistent with a conserved role for Au

68 ed for the maintenance of chromosomes at the metaphase plate, demonstrating that the functions requir

69 ell nuclei combine their genomes on a single metaphase plate, doubling descendant ploidy.

70 ation, producing chromosomes that lag at the metaphase plate during anaphase of mitosis and both meio

71 spindle structure from end to end across the metaphase plate during anaphase when the chromosomes seg

72 ustained movement of chromosomes towards the metaphase plate during chromosome congression.

73 ading edge-type filopodia and biasing of the metaphase plate during mitosis.

74 le in the movement of chromosomes toward the metaphase plate during mitosis.

75 phosphate-binding proteins, localized to the metaphase plate during mitosis.

76 scles to the alignment of chromosomes at the metaphase plate, forces must be adjusted to the proper l

77 results in loss of microtubule spindles and metaphase plate formation and causes mitotic arrest.

78 We propose that metaphase plate formation and thinning require tight con

79 two arms of the V at the position where the metaphase plate had been, a result at odds with current

80 karyotic cells, chromosomes align and form a metaphase plate halfway between the spindle poles, about

81 , if the checkpoint is inactivated after the metaphase plate has centered its position, symmetric cel

82 ssion returns nonexchange chromosomes to the metaphase plate invalidates this interpretation and rais

83 Alignment of chromosomes at the metaphase plate is a signature of cell division in metaz

84 r is that separation of chromosomes from the metaphase plate is disrupted in T18A/S19A RLC expressing

85 ndicates that the equatorial position of the metaphase plate is essential for symmetric cell division

86 pletion resulted in chromosome loss from the metaphase plate, lack of chromosome segregation and spin

87 uplicated mitotic chromosomes aligned at the metaphase plate maintain dynamic attachments to spindle

88 aneuploidy, chromosomal misalignment on the metaphase plate, meiotic spindle abnormalities, or mitoc

89 e experimentally observed disordering of the metaphase plate occurs because phosphorylation increases

90 aired and were not organized properly at the metaphase plate or along the spindle fibers during segre

91 netochores of chromosomes displaced from the metaphase plate, or in microtubule-disrupted cells, stil

92 w spheres of cells enlarge by division, with metaphase plates oriented perpendicularly to the apical

93 When we offset the metaphase plate position by creating an asymmetric centr

94 sm by providing cells enough time to correct metaphase plate position.

95 y incomplete alignment of chromosomes at the metaphase plate, possibly due to a defective spindle-ass

96 ies that consist of failure to form a stable metaphase plate, premature sister chromatid separation,

97 n and alignment of the maternal and paternal metaphase plates relative to each other.

98 iole distribution on each pole, we find that metaphase plates relocate to the middle of the spindle b

99 romosome condensation and congression on the metaphase plate result in delayed anaphase entry.

100 ips inserted into a spindle just outside the metaphase plate resulted in spindle movement along the i

101 lay defects in chromosome congression to the metaphase plate, severe chromosome missegregation, and a

102 indles, but fail chromosome alignment at the metaphase plate, sister chromatid separation, and cytoki

103 dle formation or chromosome alignment to the metaphase plate, suggesting that the 4N accumulation is

104 are properly attached and bioriented at the metaphase plate, the checkpoint needs to be silenced.

105 hromosomes in these cells are aligned at the metaphase plate, the rest remain near the spindle poles,

106 and 13, alignment of the chromosomes on the metaphase plate was disrupted in grp-derived embryos, an

107 y, completion of chromosome alignment at the metaphase plate was significantly delayed.

108 31P forms a speckled staining pattern on the metaphase plate, whereas H3 S10 and H3 S28 phosphorylati

109 hase inhibited chromosome congression to the metaphase plate with many chromosomes remaining near the

110 opy indicates that HEI-C-depleted cells form metaphase plates with normal timing after G(2)/M transit

111 There is also structure throughout the metaphase plate, with a steeper PEF potential well towar

112 hicker chromosomes that fail to align at the metaphase plate within a poorly assembled mitotic spindl

113 caused a misalignment of chromosomes on the metaphase plate without affecting global spindle structu

114 ientation of paired sister chromatids at the metaphase plate without perturbing kinetochore-MT attach

115 global cortical movement of actin toward the metaphase plate, without an apparent effect on the mitot