ライフサイエンスコーパス: metastable

1 ers, systems which appear stable are in fact metastable.

2 Once it is trapped, the HS state remains metastable.

3 viously accepted martensitic ground state is metastable.

4 ferable, although the Toth structure remains metastable.

5 Catalytic materials tend to be metastable.

6 cs simulations of a range of equilibrium and metastable [100] symmetric tilt GBs are carried out to e

7 on dislocation lines due to the migration of metastable {111}beta1/{110}Mg.

8 Metastable 1T '-MoTe2 forms directly in solution at 300

9 Confined metastable 2-line ferrihydrite, stable at ambient temper

10 hanism with implication in the regulation of metastable ABC transporters and other plasma membrane pr

11 A metastable activated CO2(-) species is also detected, be

12 oy with the B2 (CsCl-type) structure and the metastable Al9Ni2 phase.

13 d seems to originate from instability of the metastable AlxMy compound, in which significant inhomoge

14 S globules is a key step in the formation of metastable amorphous calcium carbonate (ACC), an importa

15 the transition temperature from the initial metastable amorphous phase to anatase and stable rutile

16 layer structure gives rise to the growth of metastable amorphous structures in the second and higher

17 Metallic-phase MoS2 (M-MoS2) is metastable and does not exist in nature.

18 Formation of a well-defined metastable and homogeneous glass structure with Er(3+)-i

19 This appears to render the shell metastable and make swelling possible when repulsive for

20 nception of pluripotency as an intrinsically metastable and precarious state.

21 This study reports that metastable and temperature-sensitive chemically exfoliat

22 -SiC, preferred for nuclear applications, is metastable and undergoes a phase transformation at high

23 natural tiles' or Voronoi polyhedra that are metastable and, consequently, temporally persistent.

24 exhibit a smooth crossover between isolated (metastable) and disordered lattice configurations across

25 The prefusion conformation of the HA is metastable, and the pH of fusion can vary significantly

26 ium coexistence is typically registered, but metastable antiregistered phases can be kinetically favo

27 le coming into contact with the surface of a metastable aqueous microdroplet.

28 calcite nucleation barrier surpasses that of metastable aragonite in solutions with Mg:Ca ratios cons

29 n that calcium carbonate precipitates as the metastable aragonite polymorph in marine environments, r

30 f the NO(+)NO3(-) structures are found to be metastable at T = 0 K, so experimentally reported ionic

31 niscent of diborane, is also predicted to be metastable at this pressure.

32 observations of the ionisation of neon in a metastable atomic state utilising a strong-field, few-cy

33 when the network dynamics possesses multiple metastable attractors, each attractor corresponding to a

34 ttempt was made to produce a bone-compatible metastable beta-type Ti alloy.

35 alloying and thermo-mechanical treatment, a metastable beta-type Ti-33Nb-4Sn (wt.

36 Metastable binding sites may provide a new source of all

37 tline the concept of bitopic ligands, review metastable binding sites, and discuss their potential as

38 ransient, low-affinity binding sites, termed metastable binding sites.

39 and present compelling support for not only metastable but also thermodynamically stable multimeric

40 ty, highly multivalent interactions that are metastable, but easily reversible or displaceable.

41 tylene clusters with n > 3, as well as other metastable C6H6(+) isomers.

42 We have synthesized thermodynamically metastable Ca2IrO4 thin-films on YAlO3 (110) substrates

43 es reovirus disassembly and how perturbing a metastable capsid can compromise replicative fitness.IMP

44 rs in which fibers form as well as for their metastable character.

45 When a material becomes metastable close to a thermodynamic phase transition it

46 ategy is key to tame the hot reactivity of a metastable Co(III)-carbene and elicit C-C coupling produ

47 diagram of coupled leaflets allows multiple metastable coexistences, and we illustrate the kinetic i

48 CfaA kinetically traps CfaB to form a metastable complex that can be stabilized by mutations.

49 We report a new metastable compound, beta-Zn8Sb7, which was synthesized

50 reaction, we have prepared two hypothesized metastable compounds, CoSe and CoS, with the anti-PbO ty

51 discrete polyphenic traits in epigenetically metastable conditions can contribute to a cancer-prone s

52 n of four out of the five proteins tested at metastable conditions.

53 dynamic equilibration and the persistence of metastable configurations during growth.

54 , history-dependent dynamics of intermediate metastable configurations.

55 This metastable conformational state has high affinity for Cd

56 ble to, or slower than, the lifetimes of the metastable conformational states, and when the highly an

57 namics studies indicated the presence of two metastable conformations of 3'-hydroxyechinenone, which

58 crystallization to accelerate both near the metastable critical point and almost everywhere below th

59 s of crystallization in the vicinity of this metastable critical point and throughout the metastable

60 no special advantage of the proximity of the metastable critical point on the crystallization rates.

61 This, combined with several metastable crystal phases and stoichiometries and the lo

62 re synthesized in either cubic or hexagonal (metastable) crystal structures and used as the host mate

63 t core during reduction, with formation of a metastable Cu(+) phase at the core-shell interface.

64 The corresponding metastable Cu(II)-OOH species were generated by addition

65 g ice layers, which lead to the formation of metastable cubic ice.

66 The half-life of the metastable Cys-SSH product is short and decomposition le

67 supercooled disordered state evolves into a metastable DDQC that transforms with time to the sigma p

68 is not duly covered because of in-source and metastable decay of the sialylated species.

69 The coexistence of metastable derivative structural polytypes may be a wide

70 samples with a significant retention of the metastable diamond phase.

71 inated by strong dispersion forces, enabling metastable dicationic dimers to form without covalent in

72 osed that anions can stabilize each other as metastable dimers, yet experimental evidence for these s

73 Emulsions are metastable dispersions.

74 chemical behavior created by the onset of a metastable divalent state that starts at californium.

75 joint DNA molecules-homologously paired but metastable DNA intermediates that are processed by sever

76 The metastable DNA state in the capsid provides a new paradi

77 We identify a metastable domain in the global network phase diagram sp

78 Conformational states of the metastable drkN SH3 domain were characterized using sing

79 itive plexus under low shear conditions in a metastable dynamic state.

80 Our findings suggest how metastable dynamics are important for normal brain funct

81 The nonlinear, metastable dynamics of the brain are essential for large

82 imental and theoretical model to examine how metastable dynamics relate to structural connectivity an

83 exibility, that may be a result of disrupted metastable dynamics.

84 d microexplosions in silicon produce several metastable end phases.

85 The metastable Env is triggered to undergo entry-related con

86 alent contact between the nanoconjugates and metastable Env spikes on the HIV-1 virus.

87 ts for HIV-1 specifically and putatively for metastable enveloped viruses generally.

88 First, we screen for metastable epialleles by performing genomewide bisulfite

89 More broadly, the list of candidate metastable epialleles provides a resource for future stu

90 lso identifies over 100 additional candidate metastable epialleles, and shows that these are associat

91 while the latter with f-f transition has no metastable excited state above 10,000 cm(-1), which requ

92 decompression to ambient pressure, yielding metastable fcc-hcp mixtures.

93 tion reversal as a synergistic effect of the metastable ferroelastic switching in the PMN-PT and an e

94 report results of stability analysis of the metastable fertile forest state.

95 o show that precursors that first nucleate a metastable FeSb3 compound share similar local structure

96 represented as trajectories along a chain of metastable fixed points at each level of the hierarchy,

97 ing the energetic barrier that separates the metastable flat and folded states.

98 The presence of a metastable fluid-fluid critical point is thought to dram

99 metastable critical point and throughout the metastable fluid-fluid phase diagram.

100 roduction to favor the more bioavailable but metastable Form I with limits of detection in the ppm re

101 In this paper, we provide evidence for a metastable form of graphite with an AA' structure.

102 higher sensitivity of TASC for detecting the metastable form of polyethylene glycol (PEG) compared to

103 claulansine D in the solid state exists in a metastable form, and after an induction period of 30-90

104 ica polymorph at ambient conditions although metastable forms exist.

105 v-activating ligands gradually guides Env to metastable forms that expose cryptic epitopes and that a

106 ginal models can show stable, divergent, and metastable (fragile) dynamics.

107 ing on the GB character, while those for the metastable GB states tend to be much lower.

108 merical side, the study of the properties of metastable glassy states requires thermalizing the syste

109 f the virus triggers the dissociation of the metastable Gn-Gc lattice to enable insertion of the Gc-r

110 g gold-gold atom coupling and water-mediated metastable gold complexes.

111 f the first electron, forming a high energy, metastable half reduced T3 state, is followed by the rap

112 This allows for the formation of the metastable, half reduced state and thus the complete red

113 se can initiate a transition to a long-lived metastable hidden metallic phase.

114 This allows easy quenching of the metastable high-spin (HS) state via gradual cooling (5 K

115 Conformational changes from metastable higher free energy states to lower free energ

116 c behavior caused by their ability to form a metastable hydrogen bond network.

117 ts with a urea solution, which disrupted the metastable hydrogen bonded state of PAA toward its ioniz

118 These polymorphs, which are metastable in bulk systems, form relative to other acces

119 Zincblende MnS and CoS, which are metastable in bulk, retain both the tetrahedral cation c

120 f ALS result from a set of proteins that are metastable in motor neurons, and thus prone to aggregati

121 ing alternative electrode materials that are metastable in nature, but also enables in-depth evaluati

122 The results indicate that the V3 loop is metastable in the envelope trimer on the virion surface,

123 Similarly the CsF2 (+) ion is computed to be metastable in two isomeric forms.

124 We identify OOH as a metastable intermediate in the reaction.

125 rotation of the central gamma-shaft, with a metastable intermediate located-consistently with recent

126 t the asymmetric nucleosome-RSC complex is a metastable intermediate representing partial unwrapping

127 e molecular dynamics simulations to identify metastable intermediate states and the dynamics of backt

128 loss of these two determinants 'trapped' the metastable intermediate.

129 Whether or not frayed states are metastable intermediates or short-lived configurations d

130 roleptic palladium(II) cages are kinetically metastable intermediates rather than the thermodynamic p

131 ibrational analysis of transition states and metastable intermediates suggested the mechanism of atro

132 It also revealed rare metastable intermediates that had collapsed the haematop

133 a multi-stage process requiring well-defined metastable intermediates.

134 ond-resolved chemical structure of transient metastable intermediates.

135 4 x 10(13) atoms (about 1 millicurie) of the metastable isomer (131m)Xe that were polarized using the

136 ort appears to be general, implying that the metastable isomer of a photoswitch can be isomerized to

137 We present a general strategy to synthesize metastable layered materials via topochemical deintercal

138 structural similarities between Hsp33's own metastable linker region and client proteins present a p

139 crystalline phase of bismuth can melt into a metastable liquid below the melting line through a decom

140 The decompression-induced metastable liquid can be maintained for hours in static

141 n prevents the investigation of water in its metastable liquid form.

142 to supercooled liquid, the pressure-induced metastable liquid may be more ubiquitous than we thought

143 A metastable liquid may exist under supercooling, sustaini

144 e solid may directly melt into a sustainable metastable liquid.

145 the hydrothermal synthetic accessibility of metastable materials and apply this model to understandi

146 little predictive theory exists as to which metastable materials can be made and how, impeding their

147 ftentimes incongruently melting, unstable or metastable materials.

148 films and study the phase stability of these metastable materials.

149 gas phase to a stepwise pathway, involving a metastable Meisenheimer complex, in liquid ammonia.

150 Metastable memory is then converted to stable epigenetic

151 d in biological synapses, supported by their metastable memory state transition properties.

152 in the 1T-TaS2 is driven by coupling to the metastable metallic phase coexisting within the Mott com

153 using the C35S mutant of TRX, which formed a metastable mixed disulfide bond with TG2, we demonstrate

154 after calcination are converted by CH4 into metastable MoCx Oy species, which are primarily responsi

155 Here we make use of a metastable model protein substrate, comprising a triple

156 imulations toward the structural modeling of metastable, multidomain aggregation intermediates.

157 imensional characterization of the resulting metastable nanoparticle structures.

158 Examination of metastable nanoparticles deposited on the substrate duri

159 to a snap trap, the protein transits from a metastable native form to a relaxed triggered or induced

160 enge in materials science due to the elusive metastable nature of solid solution phases.

161 tions along the bilayer normal establish the metastable nature of the inserted pore, yielding a force

162 Two metastable Ni(III) complexes, [Ni(III)(OAc)(L)] and [Ni(

163 be extended to include a broader match with metastable, non-crystalline structural motifs.

164 3PyS)]BF4 (1) leads to the production of the metastable nonheme {FeNO}(8) complex, [Fe(NO)(N3PyS)] (3

165 Viral latency can be considered a metastable, nonproductive infection state that is capabl

166 sing density functional theory, we find that metastable O precursors to the CuO phase can account for

167 chanism involves a long-lived and on-pathway metastable oligomer with S-shape chains, having a C-term

168 Recently, metastable or possibly stable nanometric aqueous cluster

169 entally reported ionic NO(+)NO3(-) is either metastable or stabilized by temperature.

170 reducing glass matrix in the red stripe or a metastable overoxidized glass in the purple stripe.

171 magnetic properties of these highly reactive metastable oxidants.

172 ution of activation energies associated with metastable oxygen defects.

173 h- (HDL) and low-density liquid (LDL) in the metastable part of the phase diagram.

174 ed upon supply-demand mismatch transients in metastable peri-infarct hot zones due to increased deman

175 er, controllable switching between PIA and a metastable phase has not been described yet, due to the

176 hexagonal polytype, a previously unreported metastable phase of gold.

177 ed material properties associated with a new metastable phase of monoclinic symmetry within bulk KNbO

178 and transformation-induced hardening of the metastable phase produces increased ductility.

179 t results for skutterudite FeSb3, which is a metastable phase that has been reported in thin film for

180 also contain local structural motifs of the metastable phase, despite their compositional disagreeme

181 with the GdFeO3-type distortion (Pnma) as a metastable phase, instead of pyrochlore structure.

182 t that the epitaxial stabilization growth of metastable-phase thin-films can be used effectively for

183 The emergence of metastable phases can thus be promoted by templating cry

184 hat lead to bistability and the formation of metastable phases in photoinduced phase transition of VO

185 Crystallization of metastable phases is particularly accessible via low-tem

186 Moreover, a variety of metastable phases were predicted, such as the covalent C

187 This can provide insight into potential metastable phases which may form in a material system, e

188 eeper insights toward the exploration of new metastable phases with exceptional functionalities.

189 ome kinetic barriers to the formation of new metastable phases, which are preserved in the surroundin

190 that hysteresis emerges as a consequence of metastable pinning of the liquid front at the defects; t

191 arbons are known to pass through a series of metastable plastic rotator phases before freezing.

192 structurally enigmatic polymorph, vaterite-a metastable polymorph of CaCO3.

193 the crystallization process are found to be metastable polymorphic structures that are different fro

194 A metastable, polymorphic hexameric crystal structure of l

195 powerful platform for predictably accessing metastable polymorphs.

196 ecruitment of Cdc24, but not Bem1, induces a metastable pool of Cdc42 that is sustained by positive f

197 It reveals the metastable pre-fusion architecture of S and highlights k

198 oduce recombinant hMPV F glycoprotein in the metastable pre-fusion conformation has hindered structur

199 conformational change, transitioning from a metastable pre-fusion conformation to a more thermodynam

200 Al12(OH)24(H2O)12](7+) ion (AlAl12(7+)) is a metastable precursor in the formation of aluminum oxyhyd

201 ng this fusion process F is converted from a metastable prefusion conformation into an energetically

202 the endosome triggers a transition from the metastable prefusion conformation to the stable fusion c

203 ular events associated with refolding of the metastable prefusion S glycoprotein to the postfusion co

204 change, going down an energy gradient from a metastable prefusion state to a highly stable postfusion

205 dynamic polymerization networks that exploit metastable prion cross-beta phases.

206 biological cell adhesion and survival, and a metastable product characterized by short monodisperse f

207 and (2) reversible transformations (that is, metastable products) driven by chemical or physical hete

208 ns are rare and often allow the formation of metastable products.

209 The serpin family of metastable protease inhibitors uses large conformational

210 ein homeostasis system associated with these metastable proteins by using a gene coexpression analysi

211 nmental stress, and expression of mutant and metastable proteins can cause an imbalance in the protei

212 However, how metastable proteins fold to these higher free energy sta

213 ir thermodynamically most stable state, some metastable proteins populate higher free energy states.

214 Metastable proteins tend to populate misfolded species t

215 pH, to larger oligomers near neutral pH, to metastable protofibrils, and finally to fibrils.

216 of non-clonal cells that were classified as metastable, pseudodiploid or chromazemic.

217 architecture of natural photosystems, and by metastable radical pair formation when photovoltaic reac

218 Here, we propose that a metastable radical state, nonreactive with oxygen, safel

219 The developed methodology for studying metastable reaction intermediates prepared with a high-e

220 es that healthy neural dynamics operate in a metastable regime, where brain regions interact to simul

221 rst time: a) Identification of four distinct metastable regions along the activation pathway, b) Kine

222 irect probe of the vibrational structure and metastable resonances that are characteristic of the rea

223 se transformation of In2O3 nanocrystals from metastable rhombohedral phase to stable cubic phase duri

224 n-selective non-radiative transitions to the metastable singlet state.

225 40 degrees C resulting in the formation of a metastable species (2).

226 easurements, and that even if a short-lived, metastable species does exist at the vacuum/water interf

227 rown from deeply supercooled liquid water is metastable stacking disordered ice.

228 s toward low oxygen chemical potential, this metastable state and the resulting enhanced selectivity

229 ended in the aqueous core suggests that this metastable state may persist for a significant fraction

230 effects in a long-lived (>100 ps) transient metastable state of Ge2Sb2Te5 with muted interatomic int

231 helix has a dual function in maintaining the metastable state of the capsid by preventing premature d

232 hrough active nitrogen species and becomes a metastable state of the catalyst (State I); next, organi

233 optimal disassembly process by balancing the metastable state of the mature adenovirus particle.

234 table, immature virus particles to a mature, metastable state primed for cell infection.

235 for RNA binding and identify an intermediate metastable state that exhibits correlated motions that c

236 It was found that PtO4 (2+) has a metastable state that is kinetically stable with a barri

237 cells is mediated by membrane proteins in a metastable state that transition to a more stable state

238 Serpins exist in a metastable state that undergoes a major conformational c

239 The second longest-lived metastable state was an unfolded, compact monomer with l

240 with a maximum at 389nm, and a photo-induced metastable state with a maximum at 497nm.

241 as and propose that sarcomas can reside in a metastable state, enabling them to become either more me

242 ally work by keeping the fouling liquid in a metastable state, with trapped pockets of air between th

243 h in vitro and in vivo, the lifespan of each metastable state.

244 ulfides, critical for folding to the active, metastable state.

245 is captured through a defect level forming a metastable state; then the local defect configuration ra

246 A metastable-state photoacid that can reversibly release a

247 This landscape reveals several metastable states along this coordinate, indicating that

248 t free-energy path between two longest-lived metastable states and confirm earlier findings of non-tw

249 mpling methods that facilitate escaping from metastable states and crossing large barriers.

250 We control the switch using SiV metastable states and observe optical switching at the s

251 advantageous in the sequence, and resulting metastable states are a consequence of a mutation-select

252 al models is challenging, even if only a few metastable states are involved.

253 history drives the material into long-lived metastable states defined by self-assembled particles wi

254 switch function, revealing the importance of metastable states for RNA-based gene regulation.

255 have identified three additional long-lived, metastable states from the bin-based model.

256 d magnetization switching between two stable/metastable states in ~300 nm sized FeGa nanomagnets deli

257 However, urea efficiently perturbs metastable states induced by cold and CD4Ms and increase

258 the HA prefusion structure (and perhaps the metastable states of other viral entry proteins) is more

259 an exhaustive structural characterization of metastable states on the basis of tertiary contact maps

260 ic barriers, enabling access to transient or metastable states that are not thermally accessible.

261 In these regimes it is the escape from the metastable states that is the key bottleneck; fixation i

262 In addition, unusual metastable states with longitudinal domain walls along P

263 total energy changes to search for potential metastable states, as well as phonon spectra to examine

264 ogression of cells and identify transient or metastable states, branching decisions and differentiati

265 e global thermodynamic minimum by populating metastable states, from which energy can be transferred

266 trained optimization eliminates intermediate metastable states, indicating that flux is enhanced in m

267 These require the involvement of metastable states, which are either able to approach the

268 small as h x 4 Hz, gives rise to long-lived metastable states.

269 ion of transition mechanisms and rates among metastable states.

270 ynamics evolve through temporal sequences of metastable states.

271 h finite populations are found in long-lived metastable states.

272 slow conformational transitions between two metastable states.

273 a into a number of dynamic processes between metastable states.

274 discoids initially self-assemble into short, metastable strands with orientational order-regardless o

275 accrued in the crystal of form I, which is a metastable structure at ambient conditions.

276 the conditions in which a compound adopts a metastable structure when it crystallizes out of solutio

277 gn of synthesis pathways toward or away from metastable structures.

278 stems, in maintaining the homeostasis of the metastable subproteome associated with Alzheimer's disea

279 esults suggest that the down-regulation of a metastable subproteome may help mitigate aberrant protei

280 aggregation-prone proteins, which make up a metastable subproteome.

281 tine dimethyl ester (CDME) in increasing the metastable supersaturation range of l-cystine, respectiv

282 rived Cu (OD-Cu) was found to correlate with metastable surface features that bind CO strongly.

283 istinct Polycomb components to deliver first metastable then long-term epigenetic silencing.

284 t-principles calculations, we discover a new metastable three-dimensional carbon allotrope entirely c

285 irreversible transition was observed from a metastable to a stable crystal phase within the nanostru

286 of down-regulated genes that encode proteins metastable to aggregation.

287 lithiation products can be thermodynamically metastable to release of O2.

288 The formation of a metastable trans-complex, catalyzed by HOPS and its SM s

289 y tuning the matrix phase's instability in a metastable TRIP-assisted dual-phase HEA.

290 e-state protein folding system, comprising a metastable triple mutant of the Fyn SH3 domain, have bee

291 360 degrees domain walls (metastable twists in magnetisation separating two domain

292 The metastable uncapped forms of recapping targets redistrib

293 elope glycoprotein (Env) trimer maintain the metastable unliganded form of the viral spike.

294 and dynamics of vapor bubbles emerging from metastable water at negative pressures.

295 wing that small amounts of aluminum could be metastable when located in the center of Si-O rings with

296 may be a room-temperature superconductor and metastable when the pressure is released and could have

297 the Xaa proline ring conformation to become metastable, which in turn confers flexibility on the tri

298 Coffinite is energetically metastable with respect to a mixture of UO2 (uraninite)

299 rm during device operation but that they are metastable, with lifetimes below a nanosecond.

300 ited {111}Al/AlN/TiN multilayers exhibit the metastable zinc-blende-structure (z-AlN).