ライフサイエンスコーパス: metathesis reaction

1 nly used as a starting material for chemical metathesis reactions).

2 ach based on esterification and ring-closing metathesis reaction.

3 to the five-membered ring by a olefin cross metathesis reaction.

4 rbon-carbon bond derived from a ring-closing metathesis reaction.

5 hts into the reaction mechanism of the enyne metathesis reaction.

6 nce on the E:Z ratio during the ring-closing metathesis reaction.

7 wire can be grown in situ through an olefin metathesis reaction.

8 )2)3Si3E3] (E = P (1a), As (1b)) by a simple metathesis reaction.

9 ) was constructed using an impressive olefin metathesis reaction.

10 ed via a highly stereoselective olefin cross metathesis reaction.

11 in a Z-selective formal vinyl bromide cross-metathesis reaction.

12 plished efficiently by a ring-closing olefin metathesis reaction.

13 segments reversibly ligated through an imine metathesis reaction.

14 hen coupled to an alkene via an olefin cross metathesis reaction.

15 xidative addition of the hydrosilane or by a metathesis reaction.

16 of the 3-methyl-substituent arising from the metathesis reaction.

17 uchi esterification, and Grubbs ring-closing metathesis reaction.

18 r, by using the newly developed alkyne cross-metathesis reaction.

19 a ruthenium(II)-catalyzed ring closing enyne metathesis reaction.

20 no single mechanism for the Ru-based olefin metathesis reaction.

21 antageously synthesized using a ring-closing metathesis reaction.

22 tereochemical control in Ru-catalyzed olefin metathesis reactions.

23 on sequence and others based on ring-closing metathesis reactions.

24 edented three-component intermolecular cross metathesis reactions.

25 ibility of their homodimers toward secondary metathesis reactions.

26 variants were prepared by exploiting alkene metathesis reactions.

27 d enyne tandem cross-metathesis-ring-closing metathesis reactions.

28 led to a variety of new quaternary salts via metathesis reactions.

29 , NH(4)(+), and Li(+) salts were prepared by metathesis reactions.

30 ciple of iron(III)-catalyzed carbonyl-olefin metathesis reactions.

31 complexes are active precursors for propane metathesis reactions.

32 loaddition and subsequent ring-rearrangement metathesis reactions.

33 f homodimerization and industrially relevant metathesis reactions.

34 ium coordination sphere by conventional salt metathesis reactions.

35 sulting catalysts evaluated using a range of metathesis reactions.

36 nd thus lead to unwanted byproducts in cross metathesis reactions.

37 intramolecular Diels-Alder and ring-closing metathesis reactions.

38 genides generally enhance the rate of alkene metathesis reactions.

39 ne and subsequent silylation by a sigma-bond metathesis reaction, affording the observed products.

40 logues were synthesized utilizing the olefin metathesis reaction and evaluated in a calcineurin A inh

41 ed, with particular emphasis on ring-closing metathesis reactions and annulation reactions based on C

42 henomenon also affects its activity in cross metathesis reactions and prohibits crossover reactions o

43 icant catalytic activity in promoting olefin metathesis reactions and provide products of high purity

44 erman rearrangement reaction, a ring-closing metathesis reaction, and an amination reaction.

45 ric methodologies: Krische allylation, cross-metathesis reaction, and THP formation via Pd(II)-cataly

46 diastereoselective Nazarov and ring-closing metathesis reactions, and a highly efficient formation o

47 andin family of compounds by catalytic cross-metathesis reactions, and a strained 14-membered ring st

48 ring-closing (ARCM) and ring-opening (AROM) metathesis reactions are detailed.

49 its on the efficiency of Ru-catalyzed olefin metathesis reactions are discussed.

50 ives, promote exceptional Z-selective olefin metathesis reactions are elucidated.

51 cumvent these barriers; however, solid-state metathesis reactions are often too rapid from extensive

52 silicon, and chemoselectivity in sigma-bond metathesis reactions, are discussed.

53 pha-chloro sulfide, and last by ring-closing metathesis reaction as the key steps.

54 (2))C(6)H(3)) ligands, catalyzes Z-selective metathesis reactions as a consequence of intermediate me

55 g beta-glycosylation and Grubbs olefin cross-metathesis reactions as the key steps.

56 s of pseudo-oligosaccharides using the cross-metathesis reaction between distinct sugar-olefins follo

57 Ir-based materials were synthesized through metathesis reaction between halide and alkali metal salt

58 duction of a chalcogel network formed by the metathesis reaction between K2PtCl4 and Na4SnS4.

59 Our results also indicate that a metathesis reaction between Mn(II) and some species on t

60 Synthesis of the sodide is accomplished by a metathesis reaction between Na and AdzH(+)X(-) in which

61 -4 and 6), were synthesized through either a metathesis reaction between Ru2(ap)4Cl and LiC(2m)Li or

62 lity of the regio- and stereoselective cross metathesis reaction between silylated alkynes and termin

63 The chalcogels are formed via metathesis reaction between the clusters [Mo(2)Fe(6)S(8)

64 des with CH-acidic methanesulfonamides and a metathesis reaction between the resulting alpha-arylated

65 of disulfides evidenced by observation of a metathesis reaction between two different disulfides pla

66 enabled by a microwave-assisted ring-closing metathesis reaction between two terminal olefins on the

67 Catalyst-dependent metathesis reactions between 3-en-1-ynamides and nitroso

68 ation effectively accelerates cross-coupling metathesis reactions between deactivated olefins.

69 Metathesis reactions between uranium tetrachloride and l

70 ound to be highly active catalysts for cross-metathesis reactions between Z-internal olefins and Z-1,

71 Studying seemingly simple metathesis reactions between ZnCl(2) and (t)BuMgCl has,

72 Anion metathesis reactions between ZrNCl and A(2)S (A = Na, K,

73 While the corresponding carbonyl-olefin metathesis reaction can also be used to construct carbon

74 th the appropriate activity, selective cross metathesis reactions can be achieved with a wide variety

75 ghlights a remarkably efficient ring-closing metathesis reaction catalyzed by Nolan ruthenium indenyl

76 s incorporated using either the ring-closing metathesis reaction catalyzed by the first generation Gr

77 rticularly notable are the unprecedented 1,4-metathesis reactions catalyzed by Ag(I) or Zn(II) to giv

78 rediction and development of selective cross metathesis reactions, culminating in unprecedented three

79 r that cleaves the C-H bond via a sigma bond metathesis reaction, during which the Co inserts into th

80 approach, a tandem ring-opening/ring-closing metathesis reaction effected an overall [2.2.1] --> [3.3

81 has exhibited such high performance in cross-metathesis reactions employing ethylene gas, with activi

82 of this pericyclic reaction with a catalytic metathesis reaction extends the versatility of cross-met

83 Furthermore, Z-selective cross-metathesis reactions, facilitated by Mo and Ru complexes

84 f bis(vinyl boronate esters) or ring-closing metathesis reactions followed by complexation with dicob

85 ynthesis features a challenging ring-closing metathesis reaction, followed by elimination and aromati

86 epsipeptide core followed by an olefin cross-metathesis reaction for installation of the thioester.

87 enum-catalyzed enantioselective ring-closing metathesis reaction for the desymmetrization of an advan

88 ne (1) and (-)-irofulven (2), which features metathesis reactions for the rapid assembly of the molec

89 ides, have been developed via a ring-closing metathesis reaction from d-ribose in eight steps.

90 ), W(6)} (L = PhC(NtBu)(2)) were prepared by metathesis reaction from the corresponding chloride with

91 ification necessary) to perform ring-closing metathesis reactions, generating 14- to 21-membered ring

92 angement and a Ru(II)-catalyzed ring-closing metathesis reaction has been developed for the preparati

93 Specifically, the catalytic olefin metathesis reaction has led to profound developments in

94 s successfully employed in Z-selective cross metathesis reactions has now been found to be highly act

95 control the stereochemical outcome of olefin metathesis reactions have been recently introduced.

96 We report a metathesis reaction in which a nitrene fragment from an

97 cribe how our investigations of ring-closing metathesis reactions in epothilone settings led to the f

98 nover numbers up to 10,000 in various olefin metathesis reactions including alkenes bearing nitrile,

99 ng 1000 were possible for a variety of cross-metathesis reactions, including the synthesis of industr

100 The types of cross metathesis reactions investigated thus far are presented

101 n to interrogate the factors influencing the metathesis reaction involving M-M, C-C, and M-C triple b

102 Here we show that through cross-metathesis reactions involving E- or Z-trisubstituted al

103 The power of this cross-metathesis reaction is demonstrated by the concise synth

104 However, the cross metathesis reaction is often accompanied by competing di

105 re, the protonation of both reactants of the metathesis reaction is predicted to be not productive ow

106 enantioselective class of ring-opening/cross-metathesis reactions is presented.

107 an efficient and selective bis ring-closing metathesis reaction leading to peptides bearing multiple

108 lar cyclization and microwave-assisted cross-metathesis reaction, leads to the first total synthesis

109 e we show that kinetically E-selective cross-metathesis reactions may be designed to generate thermod

110 present an in situ study of the solid-state metathesis reactions MCl2 + Na2S2 --> MS2 + 2 NaCl (M =

111 used in a sequence of catalytic ring-closing metathesis reactions mediated by various supported Ru ca

112 The sigma-bond metathesis reaction of 13 with Mes2SiH2 yielded HSitBuPh

113 rdinate gallium cation, has been obtained by metathesis reaction of [2,6-Mes(2)C(2)H(3)](2)GaCl with

114 l-2-ylidene]2 ) has been synthesized by salt-metathesis reaction of [L2 (Cl)Ge:] 1 with sodium phosph

115 In the cross metathesis reaction of allyl benzene with cis-1,4-diacet

116 Ichikawa's rearrangement and a ring-closing metathesis reaction of allyl carbamates is presented as

117 ted Overman rearrangement and a ring closing metathesis reaction of allylic trichloroacetimidates bea

118 e report the facile and efficient metal-free metathesis reaction of C-chiral allylic sulfilimines wit

119 C-1-disaccharide glycals based on the olefin metathesis reaction of enol ethers and alkenes is descri

120 f their steady-state conversion in the cross-metathesis reaction of terminal olefins.

121 Cross metathesis reaction of the acrolein-derived phosphonate

122 ly from solution hydrolysis, we measured the metathesis reaction of the crystallized forms with bariu

123 A cross-metathesis reaction of the second aminoallylation produc

124 From the metathesis reaction of the silver salt of methanetris(di

125 The olefin metathesis reaction of two unsaturated substrates is one

126 Here we describe the metathesis reactions of a strained eight-membered ring t

127 Ru nanoparticles were synthesized by olefin metathesis reactions of carbene-stabilized Ru nanopartic

128 Salt metathesis reactions of Cp(2)(NR(2))ZrX (X = Cl, I, OTf)

129 elative TONs of productive and nonproductive metathesis reactions of diethyl diallylmalonate are comp

130 In general, the metathesis reactions of phosphonates 2b and 2c are consi

131 Here we report catalytic Z-selective cross-metathesis reactions of terminal enol ethers, which have

132 A study of the ring-closing metathesis reactions of two bis(enynes) is presented.

133 Taking this a step further, alteration of a metathesis reaction pathway can result in either the for

134 Metathesis reactions present an approach to circumvent t

135 hosphine dissociation leads to faster olefin metathesis reaction rates, which is of direct significan

136 s shown to catalyze three important types of metathesis reactions: ring-closing metathesis, alkene di

137 Olefin cross- and ring-closing metathesis reactions run in the presence of small amount

138 herein efficiently promote benchmark olefin metathesis reactions such as the ring-closing of diethyl

139 a alkaloid, quebrachamine, through an alkene metathesis reaction that cannot be promoted by any of th

140 oduces polymer through a ring-opening alkyne metathesis reaction that is driven by the strain release

141 ate a catalytic carbonyl-olefin ring-closing metathesis reaction that uses iron, an Earth-abundant an

142 able to participate in high-yielding olefin metathesis reactions that afford acyclic 1,2-disubstitut

143 )2]2 consists of a series of oxygen/fluorine metathesis reactions that are presumably mediated by the

144 Kinetically controlled catalytic cross-metathesis reactions that generate (Z)-alpha,beta-unsatu

145 rst examples of kinetically controlled cross-metathesis reactions that generate Z- or E-trisubstitute

146 led stereoselective macrocyclic ring-closing metathesis reactions that generate Z-enoates as well as

147 future development of metal-catalyzed amide metathesis reactions that proceed via transamidation.

148 In a multiple-bond metathesis reaction, the triazacyclononane (tacn)-anchor

149 oyed to assemble the diene precursor for the metathesis reaction, three non-natural isomers of halicl

150 diates, as well as Ru-catalyzed ring-closing metathesis reaction to construct the key tricyclic cores

151 cent to the ether linkage and a ring-closing metathesis reaction to construct the nine-membered ether

152 tive stereochemistry and (2) a double olefin metathesis reaction to deliver both cyclohexene rings of

153 etic approach was the diene-ene cross olefin metathesis reaction to generate the C6-C7 olefin without

154 key step in the synthesis was a ring-closing metathesis reaction to prepare the macrocyclic ring syst

155 amount of ZnCl(2) available for the intended metathesis reaction to take place.

156 onverted via lithium halide-eliminating salt metathesis reactions to alkylated or silylated imidazoli

157 ucose, followed by a sequential ring-closing metathesis reaction using Grubbs catalysts, double-bond

158 on macromolecules underwent the ring-closing metathesis reaction using Grubbs' Type I catalyst, RuCl(

159 nerated by sequence ligation using the imine metathesis reaction was equilibrated under a variety of

160 A Grubbs' ring closing metathesis reaction was utilized to close the unusual 13

161 ation as well as overall activity for olefin metathesis reactions was examined.

162 rresponding free energy change for the imine metathesis reactions were estimated.

163 Two ring-closing metathesis reactions were then used to form the 13- and

164 forded [(dmpe)2Fe(<--:Si(Me)L)] 4 under salt metathesis reaction, while its reaction with Li[BHEt3] y

165 Furthermore, the sulfilimine/isocyanate metathesis reaction with 4,4'-methylene diphenyl diisocy

166 zontal lineCHCMe3)](+) via an intramolecular metathesis reaction with the imine fragment of the (FI)

167 5-Me(2)C(6)H(3)), undergoes an O-for-PSiR(3) metathesis reaction with the niobium phosphinidene compl

168 Olefin metathesis reactions with 3E-1,3-dienes using Z-selectiv

169 Et, and i-Pr; X = Cl, Br), are prepared via metathesis reactions with conventional alkylating agents

170 up have been shown to catalyze various cross metathesis reactions with high activity and, in most cas

171 Subsequent metathesis reactions with LiN(SO(2)CF(3))(2) or KPF(6) r

172 est that metallacyclobutane intermediates in metathesis reactions with MAP species are likely to cont

173 uoromethyl-substituted alkenes through cross-metathesis reactions with the commercially available, in

174 ting nanoparticles could also undergo olefin metathesis reactions with vinyl-terminated molecules, as

175 mmetric allylation, Prins cyclization, cross-metathesis reaction, Yamaguchi lactonization, and Julia-

176 NMR studies confirmed that the ring-closing metathesis reaction yielded a single product with the Z