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1 to (S)-hydroxyglutaric acid, a component of methanopterin.
2 d in the biosynthesis of both coenzyme M and methanopterin.
3 , a known precursor to the pterin portion of methanopterin.
4 ylated H2methanopterin, a known precursor to methanopterin.
5 ), the known precursor to the APDR moiety of methanopterin.
6 lyzes the second step of the biosynthesis of methanopterin.
7 alyzes the first step in the biosynthesis of methanopterin.
8 surement of their conversion to demethylated methanopterin and/or other intermediates in the pathway.
10 a and provides evidence that the pathways of methanopterin biosynthesis in Bacteria and Archaea are s
13 ique step to be identified in the pathway of methanopterin biosynthesis, namely, the condensation of
15 extorquens is the first report of a putative methanopterin biosynthetic gene found in the Bacteria an
16 is involved in the formation of coenzyme M, methanopterin, coenzyme F(420), and methanofuran, respec
17 ene flanking the H(2)-forming methylene-H(4)-methanopterin dehydrogenase gene (hmdA), here designated
18 ablishes the pathway for the biosynthesis of methanopterin in Methanosarcina thermophila to proceed b
20 p in the biosynthesis of the modified folate methanopterin is the condensation of p-aminobenzoic acid
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