ライフサイエンスコーパス: methylate

1 o the side chain length of the residue to be methylated.

2 n the human genome are thought to be heavily methylated.

3 promoter, and TBX21 regions of interest were methylated.

4 5% CpG islands were T-47D cell type-specific methylated.

5 ation did not occur when the target was also methylated.

6 nt samples, and the GLI3 locus is abnormally methylated.

7 the promoter for Mir133a-2 is differentially methylated.

8 mal large-subunit methyltransferase H (RlmH) methylates 23S ribosomal RNA pseudouridine 1915 (Psi1915

9 le guide RNA, dCas9-SunTag-DNMT3A is able to methylate a 4.5-kb genomic region and repress HOXA5 gene

10 (MTases) form a large family of enzymes that methylate a diverse set of targets, ranging from the thr

11 -dependent methyltransferase and found it to methylate a single protein in mitochondrial extracts, id

12 s SAHH, enabling DNA methyltransferase 3B to methylate a subset of genes.

13 arginine methyltransferase (PRMT) family and methylates a range of proteins in eukaryotic cells.

14 ntiguous regions of methylation consistently methylated across biological replicates.

15 velopmental regulators and are orthologously methylated across most human cancer types.

16 his shortcoming by investigating a series of methylated adamantanes.

17 mine how a single HG bp trapped using the N1-methylated adenine (m1A) lesion affects the structural a

18 dinucleotides and was concentrated in dense methylated adenine clusters surrounding the transcriptio

19 or screens for HP resistance identified Mrr (Methylated adenine Recognition and Restriction), a Type

20 quence involving an acidic hydrolysis of the methylated amide.

21 the utilization of methylamine, the simplest methylated amine, have mainly focussed on the fate of th

22 identifying 10 methylated nucleosides and 6 methylated amino acids.

23 A series of N-methylated amino derivatives, which are unable to underg

24 ation system methyltransferase (ctsM), which methylates an overrepresented 6-bp sequence in the chrom

25 DNA nucleoside deoxycytidine (dCyd) and its methylated analogue 5-methyldeoxycytidine (5mdCyd), know

26 itial design of a combinatorial library of N-methylated analogues of the stem peptide cyclo(d-Ala-Ala

27 everaged the differential reactivity of 2'-O-methylated and 2'-hydroxylated nucleosides to periodate

28 -replication resulted in 5,168 CpGs (39% age-methylated and 61% age-demethylated) which were characte

29 distribution patterns over gene regions for methylated and demethylated CpGs both relate to reduced

30 however, that MeCP2 can bind asymmetrically methylated and hydroxymethylated CpA dinucleotides and t

31 METHODS AND Quantitative global analysis, methylated and hydroxymethylated DNA sequencing, and gen

32 pectroscopy to characterize MeCP2 binding to methylated and hydroxymethylated mCG and mCA DNA, examin

33 alyses that characterise differences between methylated and non-methylated regions of the genome.

34 A series of methylated and octylated pyridinium and quinolinium cont

35 al chemical shift changes between binding to methylated and unmethylated CpG dinucleotides.

36 The assay is sensitive to distinguish methylated and unmethylated DNA sequences at single CpG

37 The extracted pectins were low methylated and were characterized by the predominance of

38 Many RNA-binding proteins are methylated, and we previously demonstrated that the pote

39 e of CP2 to N-varepsilon-trimethyl-lysine or methylated arginine results in cyclic peptide substrates

40 Methylated arsenic (As) species represent a significant

41 are geographic patterns in the abundance of methylated arsenic in rice that are not understood.

42 Our objective was to define whether methylated arsenic intermediates were proatherogenic and

43 conditions conducive to the accumulation of methylated arsenic, are unknown.

44 ize and composition after inorganic arsenic, methylated arsenical, or arsenobetaine exposure in drink

45 5S and C195S derivatives lost the ability to methylate As(III) and MAs(III).

46 evolutionary step toward enzymes capable of methylating As(III), the result of a loss of function mu

47 ing epialleles, and (ii) transposon-derived, methylated at all cytosines, which may or may not form e

48 of CpG dinucleotides in the human genome are methylated at cytosine bases.

49 we identified an RBM25 species that is mono-methylated at lysine 77 (RBM25K77me1), and here we used

50 he central E-box CpG has the potential to be methylated at the 5-position of cytosine (5mC), or to un

51 s that were silenced in cancer and that were methylated at their promoters.

52 Here, we isolated an As(III)-methylating bacterium, Bacillus sp. CX-1, and identified

53 In total, 4720 genes were differentially methylated between CCC patients and controls, of which 3

54 mine genomic regions that are differentially methylated between two or more biological conditions.

55 Purified BlArsM methylated both As(III) and methylarsenite (MAs[III]), w

56 Differentially methylated BRCA1 and CRISP2 regions were verified by Mas

57 A new G-CSF-driven (methylated BSA/G-CSF) arthritis model was established en

58 ed arthritis, zymosan-induced arthritis, and methylated BSA/IL-1 arthritis by both prophylactic and t

59 A variant of T2SS pseudopilin PulG remains N-methylated but is affected in interaction with the T2SS

60 as purified by Solid Phase Extraction (SPE), methylated by boron trifluoride in methanol, and injecte

61 A histone H3K9-like mimic within LIG1 is methylated by G9a and GLP and, compared with H3K9me2/3,

62 al-time sequencing, we identify the DNA site methylated by ModH5 as 5'-G(m6)ACC-3'.

63 tion elongation factor, Elongin A (EloA), is methylated by PRC2 in vivo.

64 We showed that hnRNP A1 is methylated by PRMT5 on two residues, R218 and R225, and

65 at the potent SG-nucleating protein G3BP1 is methylated by protein arginine methyltransferase 1 and 5

66 ylation reactions, whereas homolysine can be methylated by representative examples of human KMTs.

67 ional role in the disease are differentially methylated by smoking.

68 apping bisulfite-treated reads, where the un-methylated 'C's are converted to 'T's.

69 ts the first biochemically characterized non-methylating Cbl-dependent AdoMet radical enzyme.

70 ent amplification for selective detection of methylated CGIs.

71 Genes enriched with methylated CGs (mCG) were also identified in species sis

72 Methylation analysis detected methylated changes in C-IVF, but not in Natur-IVF, at ge

73 udies reveal that recruitment of KLF4 to the methylated cis-regulatory elements of these genes result

74 re heterotrophic methyl-reducers that use C1-methylated compounds as electron acceptors and formate o

75 The structural determinants of binding to methylated CpA (mCA) and hydroxymethylated DNA have not

76 , the protein stably and statically binds to methylated CpG (mCpG) regions.

77 lation readers that preferentially recognize methylated CpG (mCpG), here we report the biological fun

78 ession variants and 7 879 142 differentially methylated CpG dinucleotides.

79 We used the Methylated CpG Island Recovery Assay chip to survey DNA

80 st that MBD2 targets NuRD to unmethylated or methylated CpG islands where its distinct dynamic bindin

81 monstrate that B-lymphocytes activated by un-methylated CpG motifs, found in bacterial DNA, and beta-

82 the offspring genotype at sites close to the methylated CpG site as a proxy for DNA methylation in AL

83 XYS probes, there were 2,332 differentially methylated CpG sites (DMSs) between sexes, which were en

84 Functional analysis of differentially methylated CpG sites found genes involved in transcripti

85 e, our method identifies eQTLs by leveraging methylated CpG sites in a LIM homeobox member gene (LHX9

86 Furthermore, differentially methylated CpG sites in ASXL1 mutated MF cases are found

87 We found that differentially methylated CpG sites located to genes involved in 'cance

88 Differentially methylated CpG sites may act as mediators between geneti

89 Only few differentially methylated CpG sites were common among the three cell po

90 tated versus wild-type cases, differentially methylated CpG sites were enriched in regions marked by

91 Of differentially methylated CpG sites with the largest absolute changes i

92 We identified 4,856 differentially methylated CpGs (DMCs, adjusted p < 0.01 and absolute di

93 At 4 wk, we identified 63 differentially methylated CpGs (DMCs; false discovery rate < 5%) proxim

94 We identified 9421 sparse conserved under-methylated CpGs (scUMCs) from 31 high-quality methylomes

95 gene regulatory regions with multiple under-methylated CpGs (UMCs), such as promoters and enhancers.

96 scovery association analysis to identify age-methylated CpGs and replicated them in two independent D

97 We found that aberrantly methylated CpGs are enriched in regulatory regions assoc

98 We classified differentially methylated CpGs as being associated with genetic and/or

99 e characterized by high concentration of age-methylated CpGs at 1stExon and TSS200 and a dominant pat

100 ed 106,252 cell type-specific differentially-methylated CpGs categorized into 7,537 differentially (4

101 ich were enriched within brain modules of co-methylated CpGs during brain development and also differ

102 Unexpectedly, MBD2 binding to methylated CpGs induces DNA bending that is augmented by

103 epigenetic regulator with high affinity for methylated CpGs that localizes at pericentromeric hetero

104 etion isoform, which retains only binding to methylated CpGs, on the other hand, blocks Tet1-mediated

105 matin-loop factors and are flanked by highly methylated CpGs.

106 These may include differentially methylated CpGs/regions, transcription factor binding si

107 h the repressive chromatin marks H3K9me3 and methylated-CpGs, consistent with ORCA-bound origins init

108 ivo approaches, we demonstrated that METTL12 methylates CS on Lys-395, which is localized in the CS a

109 he APOBEC members, was reported to deaminate methylated cytosine (mC) on DNA, and this mC deamination

110 TET1 oxidizes methylated cytosine into 5-hydroxymethylcytosine (5hmC),

111 MBD1 binds to methylated cytosine-guanine dinucleotides (mCGs) within

112 methylated CpG sites and further flipping of methylated cytosines (mC) by the Set and Ring Associated

113 In mammals, methylated cytosines are found predominantly in CpGs but

114 alyses, including 12 million differentially methylated cytosines in domesticated allotetraploid cott

115 The removal of methylated cytosines requires the base excision repair e

116 ted DNA between an epigenetic signal (a hemi-methylated d(GATC) site or a single-stranded nick) and t

117 For example, methylated derivatives of lysine, arginine and glutamine

118 ctroscopy (SERS) sensor for the detection of methylated DNA (5-methylcytosine, 5mC) and its oxidation

119 the T158M mutation impaired MECP2 binding to methylated DNA and destabilized MeCP2 protein in an age-

120 replicated DNA by cooperatively binding hemi-methylated DNA and H3K9me2/3, but this model leaves a nu

121 ining a methyl-CpG-binding domain (MBD) bind methylated DNA and interpret epigenetic marks, providing

122 The genomic level of methylated DNA and its derivatives may serve as importan

123 1.8pmolL(-1)) detection of methylated DNA and its derivatives was realized with the

124 es, possess an MBD2/3 capable of recognizing methylated DNA and recruiting the associated nucleosome

125 knowledge has been gained for its conserved methylated DNA binding N-terminal ZF region; however, a

126 Interestingly, 5hmC colocalized with the methylated DNA binding protein MeCP2 and with the active

127 rified SSRP1 or its isolated CID domain to a methylated DNA fragment containing alternating purine/py

128 ially methylated gene regions (DMRs) using a methylated DNA immunoprecipitation on chip (MeDIP-chip).

129 graphene, bisulfite-treated guanine-enriched methylated DNA leads to a larger amount of the adsorbed

130 Sequencing of one molecular type (RNA, methylated DNA or open chromatin) in a single cell, furt

131 viding insight into a possible novel mode of methylated DNA recognition.

132 remodeling and deacetylase complex (NuRD) to methylated DNA to modify chromatin and regulate transcri

133 -binding protein 2 (MeCP2) selectively binds methylated DNA to regulate transcription during the deve

134 to environmental cues in all organisms with methylated DNA, as we illustrate in mouse embryonic stem

135 By using synthetically methylated DNA, we were able to train a hidden Markov mo

136 ually leads to the displacement of Mbd1 from methylated DNA.

137 appropriate residues for selectively binding methylated DNA.

138 including an EmMBD2/3 that selectively binds methylated DNA.

139 cting restoration of normal MeCP2 binding to methylated DNA.

140 e phenotype by enhancing EBNA2 activation of methylated EBV promoters.IMPORTANCE EBV establishes seve

141 Mutation of the methylated EloA residue decreased repression of a subset

142 We also identify differentially methylated enhancers in hepatocellular carcinoma (HCC) a

143 udies indicated that deletion of the histone methylating enzyme EZH2 from podocytes decreased H3K27me

144 ascent mRNA, followed by activity of histone methylating enzymes, but not through DNA methylation.

145 igenetic regulation into (i) single copy and methylated exclusively at CpGs, readily forming epiallel

146 protein arginine methyltransferase 1, which methylates EYA1 at these residues both in vitro and in c

147 Addition of Me2SO4 thus gave methylated Fc, contrary to non-organometallic aromatics

148 We identified nineteen differentially methylated gene regions (DMGRs) in early stage tumors ac

149 ammatory cells as well as for differentially methylated gene regions (DMRs) using a methylated DNA im

150 ylated regions (DMRs) and 963 differentially methylated genes (DMGs) were identified.

151 to breast cancer data to identify important methylated genes (such as polycomb target genes and gene

152 ignificant enrichment for the differentially methylated genes among the differentially expressed gene

153 ntially expressed genes, 4651 differentially methylated genes and 49 genes as antipsychotic drug targ

154 while still maintaining selectivity for DNA-methylated genes and silenced genes.

155 ependency (DM-BLD), to detect differentially methylated genes based on a Bayesian framework.

156 Methylated genes evolve faster than unmethylated genes;

157 of accurate identification of differentially methylated genes for cancer research.

158 By analyzing 320 methylated genes from 26 studies on blood samples (N = 1

159 We analyzed two sets of smoking-related methylated genes from 28 studies originating from blood

160 lso significantly overrepresented in the 661 methylated genes from two studies of buccal samples (N =

161 Interestingly, most of these differentially methylated genes function in cell adhesion and communica

162 Among 519 differentially methylated genes identified between wild and cultivated

163 ancer by determining whether smoking-related methylated genes led to enrichment in cancer-related pat

164 The differentially methylated genes overlapped with more than one-fourth of

165 ell populations have distinct differentially methylated genes relative to their normal counterparts,

166 at S-(+)-fipronil caused more differentially methylated genes that are involved in developmental proc

167 eflecting greater dosage sensitivity of body-methylated genes.

168 Extending this, variably methylated genic CGs in maize and Brachypodium distachyo

169 nucleotides is a widely conserved feature of methylated genomes but remains poorly understood.

170 to amplify the local DNMT3A concentration to methylate genomic sites of interest.

171 metric double mutants revealed that a single methylated H3K36 per nucleosome was sufficient to silenc

172 G9a is an epigenetic regulator that methylates H3K9, generally causing repression of gene ex

173 transcription factors or epigenetic editors (methylating H3K9).

174 fission yeast, histone H3 lysine 9 (H3K9) is methylated (H3K9me) at heterochromatic domains.

175 h orally bioavailable and bioactive cyclic N-methylated hexapeptides as high affinity ligands for the

176 f HER2 are limited to the involvement of tri-methylated histone 3 lysine 4 (H3K4me3) and acetylated h

177 Polycomb repressive complex 2 (PRC2-EZH2) methylates histone H3 at lysine 27 (H3K27) and is requir

178 t make important epigenetic modifications by methylating histone arginine residues.

179 groups have reported that the TAD binds with methylated histones and plays a role in DNA damage respo

180 mpound with the composition C15H8O2 and four methylated homologues were shown to accumulate as a resu

181 N2B, and of RASSF1A were significantly hyper-methylated in 50% (n = 15), 47% (n = 14), and 90% (n = 2

182 majority of sites that become differentially methylated in AML occur in regulatory elements of the hu

183 CpCpG sites methylated in both cytosines promote spreading of methyl

184 ticularly for CpG sites found differentially methylated in brain tissue between patients with schizop

185 us de novo DNA methylation of genes commonly methylated in cancer, CDKN2A, RASSF1, HIC1 and PTEN in p

186 e of 66% CG, 45% CHG and 9% CHH contexts was methylated in cotyledons.

187 the CYP11B1 promoter was significantly less methylated in CPA than in adjacent unaffected adrenal ti

188 bserved that up to 2.8% of all adenines were methylated in early-diverging fungi, far exceeding level

189 th embryonic stem cells and brain from those methylated in either one of the samples.

190 ese regions were consistently differentially methylated in every subtype and all implicated genes are

191 we found that the same adenosine residue is methylated in mice and human primary cells.

192 biological pathways were also differentially methylated in RA B cells.

193 , the circadian "master clock," which is DNA methylated in region-specific manner.

194 revealed that 28 regions were differentially methylated in relation to tea consumption in women.

195 ng to DNAJC16 and TTC17, were differentially methylated in relation to tea consumption in women.

196 ng brain development and also differentially methylated in the brains of boys and girls.

197 uni when only a subset of the CtsM sites are methylated in vitro.

198 Genes differentially methylated included those with established roles in asth

199 osylmethionine (SAM) methyltransferases that methylates inorganic As(III) into mono- (MAs(III)), di-

200 senic (3) methyltransferase (As3MT) to yield methylated intermediates.

201 tween histone H3 variants and preferentially methylate K27 on H3.1.

202 The maternally methylated KvDMR1 ICR regulates imprinted expression of

203 ation of TET1 relieves its repression of the methylated Lhb gene promoter, which is then hydroxymethy

204 Interaction with methylated LIG1 promotes the recruitment of UHRF1 to DNA

205 l type-specific validation of differentially methylated loci was performed after fluorescence-activat

206 tatistical power of detecting differentially methylated loci.

207 A differentially methylated locus associated with triglycerides and high-

208 poprotein cholesterol-related differentially methylated locus.

209 plant homeodomain (PHD) finger of Set3 binds methylated lysine 4 of histone H3 in vitro and in vivo;

210 file the binding of chromodomain proteins to methylated lysine peptides derived from the histone 3 pr

211 Polycomb repressive complex 2 (PRC2) methylates lysine 27 in histone H3, a modification assoc

212 In this study, we show that WHSC1L1 mono-methylates lysine 721 in the tyrosine kinase domain of E

213 ns and are mostly unmethylated within highly methylated mammalian genomes.

214 ysteine residues suggest that the ability to methylate MAs(III) may be an evolutionary step toward en

215 AfArsM1 methylates MAs(III) but not As(III).

216 gestion of both MB substrate and maintenance methylated MB corresponds to de novo methylation event.

217 These results suggest that when decoys are methylated, MBD proteins can block them and thereby allo

218 s(V)) and arsenite (As(III)) into more toxic methylated metabolites methylarsenite (MAs(III)) and dim

219 Several methylated motifs were highly conserved across spatiotem

220 4F while allowing IFIT1 to select against N1 methylated mRNA.

221 When Pol III genes are hypo-methylated, MYC amplifies their transcription, regardles

222 The ribose of RNA nucleotides can be 2'-O-methylated (Nm).

223 ted the workflow by correctly identifying 10 methylated nucleosides and 6 methylated amino acids.

224 en situated at the third codon position, the methylated nucleosides did not compromise the speed or a

225 We provide evidence of the existence of free methylated nucleotides capable of distinguishing plasma

226 tion with an open chromatin mark, histone H3 methylated on lysine 4.

227 egions results in enrichment of the targeted methylated or unmethylated minority-epigenetic-alleles.

228 the amplification of arsM genes to identify methylating organisms.

229 ent CpG sites in mammalian genomes can be co-methylated owing to the processivity of methyltransferas

230 sizer, containing neutral nucleotides with a methylated phosphate group.

231 alogenated piperazic acid, and a novel delta-methylated piperazic acid in svetamycins B-C, E, and G.

232 lygenic risk score-associated differentially methylated positions and regions, which are not enriched

233 genes implicated by the most differentially methylated probes implicated gamma-aminobutyric acid (GA

234 ntially methylated regions or differentially methylated probes, after adjustment for age, sex, race/e

235 d twins) were not enriched by differentially methylated probes.

236 ns of the methyl group of SAM2 appear in the methylated product.

237 ment cultures converted 63% of arsenite into methylated products, with dimethylarsinic acid as the ma

238 t the upstream CGI and a lack thereof at the methylated proximal promoter itself.

239 silent, yet a sizable fraction of genes with methylated proximal promoters exhibit elevated expressio

240 ved mechanism of transcription of genes with methylated proximal promoters in a tissue-specific fashi

241 molecular dynamics simulations of PulG(E5A), methylated PulG(WT) (MePulG(WT)), and MePulG(E5A) varian

242 ng requires ICMT in part because it requires methylated RAB7 and RAB8.

243 A differentially methylated region at the Ascl1 promoter, isolated from m

244 We identified a differentially methylated region in the promoter of the proprotein conv

245 Multiple differentially methylated regions (DMR) could be identified in atherosc

246 A total of 853 significantly differentially methylated regions (DMRs) and 963 differentially methyla

247 roach (called ABBA) to detect differentially methylated regions (DMRs) from whole-genome bisulfite se

248 Of 811 differentially methylated regions (DMRs) identified in ACF, 537 (66%) w

249 ancreatic islets, to identify differentially methylated regions (DMRs) in diabetic islets, and to inv

250 Differentially methylated regions (DMRs) in each methylation context sh

251 gulation and the detection of differentially methylated regions (DMRs) is enthralling for many diseas

252 within a sample by leveraging differentially methylated regions (DMRs) specific to cell type, identif

253 66 and 2136 genes containing differentially methylated regions (DMRs) with negative correlation betw

254 These differentially methylated regions did not occur at the loci of differen

255 onal pipeline that identifies differentially methylated regions efficiently.

256 al approaches for identifying differentially methylated regions from high-throughput bisulfite sequen

257 alysis identified a number of differentially methylated regions in TET2-deficient versus wild-type CD

258 ines and determined that over 99.998% of the methylated regions in the genome are stably inherited ac

259 ere able to identify specific differentially methylated regions in the parental genomes that are asso

260 er showed that these parental differentially methylated regions most likely mediate the remodeling of

261 erise differences between methylated and non-methylated regions of the genome.

262 We identify 19 differentially methylated regions on chromosome 6 harboring MHC gene cl

263 nificant methylation changes, differentially methylated regions or differentially methylated probes,

264 The differentially methylated regions show enrichment for biological functi

265 tal immune cells harbored 589 differentially methylated regions that distinguished IIS children who d

266 d controls were conducted and differentially methylated regions were validated.

267 dation of selected cord blood differentially methylated regions, using bisulfite amplicon sequencing.

268 network of asthma-associated, differentially methylated regions, was selectively increased in asthmat

269 nd CD8(+) (P = 2.10 x 10(-8)) differentially methylated regions.

270 ifferentially (46.6% hyper- and 53.4% hypo-) methylated regions.

271 sociated with the neighboring differentially methylated regions.

272 ng and RNA-seq show that dCas9-SunTag-DNMT3A methylates regions of interest with minimal impact on th

273 The effects of methylated ribonucleosides on translation could be attri

274 Furthermore, HNRNPG binds m6A-methylated RNAs through its C-terminal low-complexity re

275 ir, which is mediated through its ability to methylate RUVBL1, a cofactor of the TIP60 complex.

276 at the embryos with NTD failed to adequately methylate septin2, a key regulator of cilium structure a

277 that there are also many TFs that prefer CpG-methylated sequences.

278 ng whole blood highlighted 36 differentially methylated sites associated with mLOY.

279 Quantitative differences in methylated sites between these three tissues suggest tis

280 g we followed up the two most differentially methylated sites in 214 vaginal cell samples serially co

281 aA and the RNA methyltransferase RlmN, which methylates specific nucleotides in rRNA and tRNA.

282 The differential ability of C-methylated spermidine analogues to functionally replace

283 These proteins recognize histone H3 lysine 9 methylated tails via their chromodomain and recruit addi

284 gestion of unmethylated targets, and leaving methylated targets intact; and vice versa.

285 ly two-fold more likely to be differentially methylated than non-transcribed genes.

286 First, we show that ATXR5 preferentially methylates the R/F-K*-S/C-G/A-P/C motif with striking pr

287 s well as the S-methyltransferase DTCMT that methylates the resulting dithiocarbamate, together compl

288 ism genes, including PPAR-gamma, by directly methylating their promoters.

289 Most homeobox genes were hypo-methylated throughout gestation, suggesting that DNA met

290 odon loop of Trypanosoma brucei tRNA(Thr) is methylated to 3-methylcytosine (m(3)C) as a pre-requisit

291 of methylation, functional classification of methylated transcripts, and position bias within the tra

292 tionship between these two enzymes when they methylate two distinct sites of the same substrate may a

293 As are unusual in that they are predicted to methylate two nucleotides in a single target region.

294 aluate the likelihood that a region is truly methylated under any given experimental condition, allow

295 NaME reactions (177-plex) using dilutions of methylated/unmethylated DNA and in DNA from clinical lun

296 viral transcription factor EBNA2 to activate methylated viral promoters that are expressed in type II

297 moter methylation and vice versa (1425.1 for methylated vs 1828.0 for unmethylated; P < .001).

298 of SacII when the hemimethylated CpG site is methylated, which inhibits Sau96I cleavage.

299 In this study, we found promoter methylated WIF1 in both CS cell lines (CS-1 and SW1353)

300 ted pectin from OFI cladodes (EAEPC) was low methylated, with a high uronic acid content, a water and