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1 cell populations by assembling cell-specific methylation patterns.
2 ulatory motifs underlies some human-specific methylation patterns.
3 a good model to study the inheritance of DNA methylation patterns.
4 enomic annotations and with estimation of co-methylation patterns.
5 including both tissue-specific and invariant methylation patterns.
6 ations in urine are a robust predictor of As methylation patterns.
7 ymes in the establishment and maintenance of methylation patterns.
8 ondensation without altering genome-wide DNA methylation patterns.
9 astic cells exhibiting global changes in DNA methylation patterns.
10 specificity subunits resulting in different methylation patterns.
11 silencing factor and regulator of genome DNA methylation patterns.
12 pecific transcription factors and changes in methylation patterns.
13 of cells owing to changes in DNA and histone methylation patterns.
14 acterised by an increased variability in DNA methylation patterns.
15 tion of SAHH may globally influence cellular methylation patterns.
16 enes and that 5Aza treatment restored normal methylation patterns.
17 and do not capture the diversity of existing methylation patterns.
18 Drosophila melanogaster lack detectable DNA methylation patterns.
19 s culture conditions displayed different DNA methylation patterns.
20 dback loops to complex self-perpetuating DNA methylation patterns.
21 s, along with their chromatin states and DNA methylation patterns.
22 lease (DSN) to remove excess DNA with normal methylation patterns.
23 per characterisation of the heterogeneity of methylation patterns.
24 etween maternal plasma lipids and infant DNA methylation patterns.
25 failed to reveal any evidence of defined DNA methylation patterns.
26 at affect both histone modifications and DNA methylation patterning.
27 , is a key regulator of EBV latency type DNA methylation patterning.
29 This study provided some evidence that DNA methylation patterns acquired in the founder animal can
30 Nevertheless, several genes showed variable methylation patterns across gestation, with a general tr
31 played higher intrasample variability of DNA methylation patterns across the genome, which appears to
32 during pregnancy may result in abnormal gene methylation patterns and contribute to developmental pro
35 ation system causes changes in site-specific methylation patterns and gene expression patterns that m
37 he DNA methyltransferase Dnmt1 maintains DNA methylation patterns and genomic stability in several in
38 on have revealed that dynamic changes in DNA methylation patterns and histone modifications accompany
39 hat NDGs acquired divergent cis-elements and methylation patterns and may experience sub-functionaliz
41 Finally, prolonged exercise affected gene methylation patterns and micro-RNA content in the sperm
43 light the conservation and divergence of DNA methylation patterns and regulatory machinery in plants
44 the complete genome sequence, as well as DNA methylation patterns and small RNA transcriptomes, was a
45 and AFP- HCC tumors have distinct global DNA methylation patterns and that increased DNA methylation
46 ic variation in human disease, cell-specific methylation patterns and the cellular heterogeneity pres
47 the mechanistic basis of human-specific DNA methylation patterns and the interpretation of inter-spe
48 e of SDG8, we examine how the global histone methylation patterns and transcriptome were altered in t
50 strategies involved in setting up normal DNA methylation patterns and understanding how this stable e
51 aralogs, compared their cytosine and histone methylation patterns, and analyzed the sequence evolutio
52 ography tandem mass spectrometry, histone H3 methylation patterns, and markers of mitochondrial respi
53 a functional role of spatial correlations in methylation patterns, and provide a mean to quantitate s
54 e the understanding of antisilencing, genome methylation patterns, and regulation of alternative RNA
56 ironmental stressors may have on genome-wide methylation patterns, and to what extent epigenetics may
58 ms which recognise heterogeneous outlier DNA methylation patterns are able to identify many sites in
59 yltransferases (DNMTs) and disruption of DNA methylation patterns are associated with carcinogenesis
60 methylation in angiosperms and show that DNA methylation patterns are broadly a reflection of the evo
66 that genome-wide cancer hyper- and hypo- DNA methylation patterns are independent processes, controll
68 that, with the exception of cerebellum, DNA methylation patterns are more homogeneous between differ
70 n DNA methylation showed that changes in DNA methylation patterns are required for the accurate regul
78 cts of changes in leukocyte fractions on CpG methylation patterns as well as the potential importance
79 six alternative specificities with distinct methylation patterns, as defined by single-molecule, rea
80 ly a minority of mTECs, independently of DNA-methylation patterns, as small inter-chromosomal gene cl
81 es featuring all of the reported acetylation/methylation patterns associated with Bp and Bm LPS O-ant
82 a new approach for discovering differential methylation patterns associated with expression change u
85 covered characteristic accessibility and DNA methylation patterns at DNase hypersensitive sites (DHSs
88 fungal development, we profiled genome-wide methylation patterns at single-nucleotide resolution dur
89 ifferentially methylated sites, the distinct methylation patterns at some genes suggest parent-specif
90 vides a simple explanation for non-canonical methylation patterns at some loci or in certain COMPASS
94 e two mutant subpopulations exhibit distinct methylation patterns at their imprinting control regions
95 al DNA methylation level increased and their methylation patterns became more distinct from those of
97 hylation in both strains; however, the basal methylation pattern between strains shows striking diffe
98 rmation derived from the similarity of local methylation pattern between tissues, the methylation inf
99 ach methylation context showed very distinct methylation patterns between cell types and in response
101 pluripotent stem cells (iPSCs) show variable methylation patterns between lines, some of which reflec
102 of the loci within this family show constant methylation patterns between the three cell types wherea
104 , including a locus that itself controls DNA methylation patterns, but with most of the changes affec
106 ation between nucleosome positioning and DNA methylation patterns can arise from the variations in nu
107 Here we show that in vivo and in vitro DNA methylation patterns can be horizontally transferred int
108 e, and showed that horizontally acquired DNA methylation patterns can increase or decrease cell fitne
111 bled identification of both sequence and DNA methylation pattern changes in a single experiment.
113 d that Natur-IVF embryos have expression and methylation patterns closer to in vivo blastocysts.
114 that malignant meningiomas have distinct DNA methylation patterns compared to their benign and atypic
120 rly 40 y since it was suggested that genomic methylation patterns could be transmitted via maintenanc
121 K4 and di- and trimethylated on H3K36, an H3 methylation pattern distinct from that recognized by the
124 ey mediator of inheritance of epigenetic DNA methylation patterns during cell division and is a putat
125 n, which results in faithful transmission of methylation patterns during cell division and, at least
127 thesized that analysis of alterations in DNA methylation patterns during healthy HSC commitment and d
128 In mammals, faithful inheritance of genomic methylation patterns ensures proper gene regulation and
134 quantitative high-resolution analysis of DNA methylation patterns from bisulfite sequencing data, inc
136 hpat", that extracts and displays clonal DNA methylation patterns from massively parallel sequencing
137 sing this approach, we identify critical DNA methylation patterns from previously inaccessible cohort
141 provide insights into complementary de novo methylation patterns governing regulation of HSC fate de
142 ation between nucleosome positioning and DNA methylation patterns has been reported in literature.
143 reliable detection of disease-associated DNA methylation patterns has major potential to advance mole
145 transferases or demethylases, yet discordant methylation patterns have also been observed, which are
147 studies examining RNA transcription and DNA methylation patterns have revealed profound insights in
148 is strikingly better on chromosome X, where methylation patterns have unique inter-tissue variabilit
150 ome genomic loci may demonstrate bipolar DNA methylation pattern, i.e. hypermethylated in one cell su
151 g a DNA amplification efficiency of 70% with methylation patterns identical to the respective bulk DN
152 ally, we show that the regional differential methylation patterns identified on sparse array data are
153 ic drug treatment in vitro We found that DNA methylation patterns identify divergent patient subgroup
154 in DNA methylation, whereas well-structured methylation patterns imply deterministic methylation eve
155 cument the expression of lncRNAs and the DNA methylation pattern in calcific aortic valve disease.
156 ing healthy controls revealed a distinct DNA methylation pattern in psoriasis compared with controls.
157 l epigenetic bias, here we have profiled DNA methylation patterns in a cohort of 57 individuals with
158 Interest is in modelling the changes in methylation patterns in a CpG island in the first exon o
159 rmined that d-flow regulates genome-wide DNA methylation patterns in a DNA methyltransferase-dependen
160 onstrate that d-flow controls epigenomic DNA methylation patterns in a DNMT-dependent manner, which i
161 pply our method to determine allele-specific methylation patterns in a human genome and identify hund
162 ole of SAMe in establishing the aberrant DNA methylation patterns in a mouse model of diabetic neurop
164 hyl-donor availability influenced global DNA methylation patterns in both adult mice and their offspr
165 mining our previously reported study of DNA methylation patterns in breast tissue (103 cancer, 21 no
170 and control animals highlighted differential methylation patterns in Daphnia upon exposure to Microcy
173 ct roles of DNMT1-dependent and -independent methylation patterns in genome stability and regulation
176 Several studies show alterations in DNA methylation patterns in iAs-mediated pathogenesis, but t
179 hat ecRNAs are fundamental regulators of DNA methylation patterns in neuronal systems, and reveal a p
181 al tissue environment directly modulates DNA methylation patterns in normal differentiated cells in v
182 ssiveness of individual PC foci based on DNA methylation patterns in primary PC foci and matched lymp
183 ed in genome-wide association studies of DNA methylation patterns in relation to environmental exposu
184 tudy to examine global transcription and DNA methylation patterns in specific immune cell populations
187 OpvAB(ON) cell lineages display opposite DNA methylation patterns in the opvAB regulatory region: (i)
189 ical function for cell type-specific histone methylation patterns in the regulation of behavioral res
191 ovides the ability to investigate clonal DNA methylation patterns in unprecedented detail and scale,
192 tudied epigenetic phenomenon; alterations in methylation patterns influence human phenotypes and risk
193 netic information encoded in the genomic DNA methylation pattern is translated by methylcytosine bind
195 th similar, albeit less dramatic, changes in methylation patterns, leading to the hypothesis that age
196 ailure to properly establish or maintain DNA methylation patterns leads to cell dysfunction and disea
198 DNA transposon, suggesting that the observed methylation pattern may be independent of the mode of in
200 d was further validated by comparing the CpG methylation pattern, methylation profile of CGIs/promote
202 With this system we demonstrated that DNA methylation patterns not only accompany the horizontal t
205 sed HT-TREBS to individually analyze the DNA methylation pattern of 4799 IAP LTR retrotransposons in
206 r analysis revealed that a combined promoter methylation pattern of low methylation levels in ALDH1A2
207 ble common epigenetic change, we studied DNA methylation pattern of more than 450 000 CpG sites in 44
208 The aim of this study was to determine the methylation pattern of the entire promoter of ERVW-1 and
211 utero exposure to BPA altered the global CpG methylation pattern of the uterine genome, subsequent ge
212 idence that cigarette smoking alters the DNA methylation patterning of the SAE and that, for some gen
213 control and motivational processes with DNA methylation patterns of 60 candidate genes in boys at ea
214 In this study, we measure the passenger methylation patterns of a specific CpG region in 9 color
215 nt plant organs were in agreement with the O-methylation patterns of alkaloids in G. flavum determine
216 stable with an epivariation frequency in DNA methylation patterns of at least two orders of magnitude
219 st, second and third trimesters to determine methylation patterns of homeobox gene promoters across g
220 ve analysis, we investigated genome-wide DNA methylation patterns of meningiomas from ten European ac
223 dopsis reproduces the strong linker-specific methylation patterns of species that diverged from flowe
225 Overall, this study demonstrates that DNA methylation patterns of the Lhx3 gene are associated wit
226 evidence to support the hypothesis that the methylation patterns of the two alleles evolve independe
227 encing (ChIP-seq) experiments show that H3K4 methylation patterns on active genes are not universal o
228 dy, we evaluated the effects of specific DNA methylation patterns on modulating nucleosome conformati
229 ons, we examined the effect of altered H3K79 methylation patterns on UV-induced G1/S checkpoint respo
233 as demonstrated by widespread changes to DNA methylation patterns, redistribution of histone marks an
236 y cohort data unveils cell type-specific DNA methylation patterns related to HIV-associated CI and pr
237 l approach, we observed in the isolated CTCs methylation patterns resembling more those of epithelial
238 ne DNA methyltransferases (Mod) alter global methylation patterns resulting in changes in gene expres
242 observed that specific sequence and cytosine methylation patterns surrounding the targeted guanine re
244 ed a metric of the HSC commitment-associated methylation pattern that proved to be highly prognostic
245 type with high tissue 2HG and a distinct DNA methylation pattern that was associated with poor progno
246 rthermore, we identified distinct epigenetic methylation patterns that are conserved across tissues,
247 ssfully employed for characterisation of DNA methylation patterns that are essential for the diagnosi
248 ferences in colorectal cancer are related to methylation patterns that extend beyond the single-gene
249 le (SWI/SNF) chromatin remodeling and global methylation patterns that may allow for future therapeut
250 ns can be used to decipher mutation-specific methylation patterns that may lead to therapeutic insigh
255 sts, they had unique gene expression and DNA methylation patterns that were, in part, indicative of t
259 Dnmt2-dependent methylomes lack defined DNA methylation patterns, thus necessitating a systematic re
260 CG methylation is higher in pollen, allowing methylation patterns to be accurately inherited across g
262 f Brachypodium distachyon and compared genic methylation patterns to those of rice (Oryza sativa ssp.
263 mation, such as histone modification states, methylation patterns, transcription factor binding sites
264 iPS cells differed and retained residual DNA methylation patterns typical of parental somatic cells.
267 20%) were not associated with a specific DNA methylation pattern using an unsupervised approach.
269 e for directly detecting epimutations in DNA methylation patterns using single-cell, locus-specific b
272 d with symptoms (P < 0.05), and baseline DNA methylation pattern was found to be predictive of sympto
273 significant difference in the TNFA promoter methylation pattern was observed in samples biopsied dur
279 - treated FAP patient tissue after which the methylation patterns were visualized by Next Generation
280 ny other genes in these classes have similar methylation patterns, whether the genes are active or re
281 lay developmentally regulated brain-specific methylation patterns which are lost in Smchd1 homozygous
282 its intermediates are known to alter the DNA methylation pattern, which is a critical regulator of ep
284 st widely used technologies in analyzing DNA methylation patterns, which are important in understandi
285 and association with genome-wide cancer DNA methylation patterns, which are largely independent of c
286 ing alignment approach for investigating DNA methylation patterns, which significantly improves the n
287 enetic background to transcriptional and DNA methylation patterns while controlling for cell line clo
288 s suggests that SE origin contributes to DNA methylation patterning, while shared skin tissue environ
290 iversity Vienna (Vienna, Austria), assessing methylation patterns with an alternative methylation chi
292 ows users to perform integrative analysis of methylation patterns with other genomic features togethe
294 ation embryos, display relatively stable DNA methylation patterns, with 70-80% of all CpGs being meth
295 w 381 genes with significantly different CpG methylation patterns, with the vast majority being more
298 stem in Escherichia coli where different DNA methylation patterns within the cis-regulatory sequence
299 ion assays revealed allelic lineage-specific methylation patterns within the HLA-A promoter region wh
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