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1 ion included clinical factors and tumor MGMT methylation status.
2 GATA1, and USF1) factors was not affected by methylation status.
3 Efficacy did not differ by methylation status.
4 l donor betaine to modulate inflammatory and methylation status.
5 omide for newly diagnosed GBM, regardless of methylation status.
6 utarate (2HG) can cause changes in chromatin methylation status.
7 nhancer activities in response to changes in methylation status.
8 ethylation, histone acetylation, and histone methylation status.
9 H19) and potentially other genes of unknown methylation status.
10 ghtly coordinated and coupled to target site methylation status.
11 he two sense pancRNAs did not change the DNA methylation status.
12 activity, independent of the MMP13 promoter methylation status.
13 . coli, irrespective of its dam, dcm, or hsd methylation status.
14 ent gene transcripts without affecting FoxP3 methylation status.
15 on of these genes through changes in histone methylation status.
16 ld be related to the modification of the DNA methylation status.
17 uanine-DNA methyltransferase (MGMT) promoter methylation status.
18 ing its expression by regulating its histone methylation status.
19 e to recombine correlated inversely with its methylation status.
20 non-normalised hybridisation data to define methylation status.
21 y in other assay formats used to analyze CpG methylation status.
22 s located in 6q12-27 for characterization of methylation status.
23 d by protein isoforms, transcribed mRNA, and methylation status.
24 ffect of PTSD on cortical thickness via SKA2 methylation status.
25 tematic re-evaluation of the mosquito genome methylation status.
26 aintenance of lineage-specific chromatin and methylation status.
27 ntified, and O-GlcNAc levels regulated their methylation status.
28 e-DNA-methyltransferase gene (MGMT) promoter methylation status.
29 the silenced gene with no change in promoter methylation status.
30 lls, also identifying in the RORC2 and IL17A methylation status a novel tool for their distinction fr
32 s were used to identify associations between methylation status and 21 dietary variables hypothesized
34 our claim that a methyl-rich diet can affect methylation status and consequent transcriptional regula
35 t epi-allelic haplotypes, annotated with CpG methylation status and DNA polymorphisms, from whole-gen
36 interactions at enhancers, we find that DNA methylation status and enhancer activity during early ze
38 ant association was observed between RASSF1A methylation status and HNSCC risk under a random-effects
39 ism may play an essential role in regulating methylation status and liver injury in Wilson's disease
40 These results also suggest that promoter methylation status and miRNA expression levels represent
41 f the ferT RNA was also regulated by the DNA methylation status and paralleled the expression profile
44 copy number variations, chromatin structure, methylation status and transcription factor binding.
46 F (V600E) mutation status, mut-L homologue 1 methylation status, and disease-specific survival in the
47 I "PGFRA," RTK II "classic"), MGMT promoter methylation status, and hallmark copy number variations
49 a late step of reprogramming associated with methylation status, and implicated a secondary set of pl
50 levels, anti-ADI-PEG20 antibody titer, ASS1 methylation status, and metabolic response by 18F-fluoro
51 lical structure facilitates sampling of H3K4 methylation status, and proffers H3K9 and other residues
52 regardless of its sequence, CpG content, or methylation status, and required signaling through the a
53 IL-4, INF-gamma and Foxp3 gene promoter DNA methylation status, and their correlation with final cha
55 eded to investigate the potential of DNA-(de)methylation status as a predictor for BF as well as for
57 I IFN-alpha/beta protein levels with the DNA methylation status as well as the expression profiles of
59 e methylation and demethylation and that the methylation status at a single lysine residue confers di
61 at inflammatory cytokines can change the DNA methylation status at key CpG sites, resulting in long-t
62 otency-associated transcription factors, DNA methylation status at pluripotent cell-specific genes, a
63 abled quantitative measurement of single CpG methylation status at relatively low cost and sample inp
64 tion imparts differential maintenance of DNA methylation status at Tet1 targets, ultimately contribut
66 sequencing has been used to characterize DNA methylation status at the genome scale, but suffers from
68 dependently established the correct cytosine methylation status at the target CG of each molecule tes
69 d that there was a strong correlation on the methylation status between different generations in the
70 nia, together with the stable inheritance of methylation status between generations, suggests either
71 transcript levels (by quantitative PCR), DNA methylation status (by bisulfite pyrosequencing), and GA
72 a classification-based procedure, called the methylation status calling (MSC) procedure, to make bina
73 mate that Q40 values (0.01% error rates) for methylation status calls could be achieved by reading si
79 methylguanine-DNA methyltransferase promoter methylation status, contrast enhancement, initial treatm
82 grate their genome into the host genome, the methylation status during this stage has been studied ex
83 as validated by quantification of global DNA methylation status following treatment of cells with the
84 have been developed to interrogate cytosine methylation status genome-wide, however these assays mus
86 equencing is widely used for analysis of DNA methylation status (i.e., 5-methylcytosine [5mC] vs. cyt
87 DNA (gDNA) to analytically infer polymorphic methylation status (i.e., 5-methylcytosine [5mC] vs. cyt
88 gulatory T cell-specific demethylated region methylation status in 1-month biopsy samples revealed a
89 By measuring reelin expression and promoter methylation status in 39 primary breast tumors, as well
90 ations establish a link between SAMe and DNA methylation status in a defined biological system, provi
91 chronological profile of the genome-wide DNA methylation status in a human myoblast differentiation m
94 thylViewer can simultaneously query cytosine methylation status in bisulfite-converted sequences at a
95 enous Bt toxins, Bt-transgene expression and methylation status in Bt rice exposed to two levels of C
98 itors allow unprecedented control of the DNA methylation status in cells and will lead to further adv
99 ixed cell population, the change in promoter methylation status in chronic periodontal disease sugges
100 dy, we investigated gene copy number and CpG methylation status in CRPC to gain insight into specific
104 rmed DNA bisulfite sequencing to compare the methylation status in postmortem retina pigment epitheli
105 inting but is a strong factor in determining methylation status in preimplantation embryos, suggestin
106 stered these profiles according to their DNA methylation status in primary normal and tumor tissues.
107 ntial of these sensors in monitoring histone methylation status in response to histone methyltransfer
114 ations and epimutations (changes in cytosine methylation status) in mutation accumulation (MA) lineag
116 long-term influence of morphine on redox and methylation status (including DNA methylation levels) in
118 ation at both K4 and K79, indicating that H3 methylation status is not solely dependent on H2B ubiqui
120 re is a clear rational for the definition of methylation status, it uses DMH data without between-gro
121 )-methylguanine-DNA methyltransferase (MGMT) methylation status may be an important determinant of tr
122 of active DNA demethylation, how genome DNA methylation status might be sensed to regulate the expre
124 drocytes, consistent with the differences in methylation status observed in vivo in normal and human
127 We have used this method to determine the methylation status of >275 million CpG sites in human an
135 Using Sequenom MassARRAY we measured the methylation status of 68 CpGs 5' from five candidate gen
136 The method was scaled to interrogate the methylation status of 77,674 CpGs in the promoter region
138 4 levels was observed to be dependent on the methylation status of a miR-494 promoter-associated CpG
140 get poorly transcribed loci by "reading" the methylation status of a particular lysine residue of his
144 lity in liver tissue, based on comparing the methylation status of adjacent CpG sites on long sequenc
145 ite-converted whole genomes to determine DNA methylation status of an entire genome, which has hereto
146 bisulfite sequencing studies to address the methylation status of Arabidopsis thaliana telomeres.
147 expression of regulatory markers, and FOXP3 methylation status of blood TFR is comparable with tonsi
150 nstitutive and T-cell activation-induced DNA methylation status of CCR5 cis-regulatory regions (cis-r
153 f single CpG sites are representative of the methylation status of corresponding regions of interest.
154 sferase in mouse and human and regulates DNA methylation status of CpG island-associated promoters in
155 lopment of allergic disease, we examined the methylation status of CpG loci within the promoter regio
156 viruses--particularly small DNA viruses--the methylation status of CpG motifs is rarely known and the
160 for the multiplexed interrogation of the DNA methylation status of cytosine-guanine dinucleotide isla
161 e high level of accuracy for identifying the methylation status of cytosines in DNA, could find broad
162 Our integrated analysis demonstrates that methylation status of different genomic regions may play
163 arate-dependent dioxygenases that modify the methylation status of DNA by successively oxidizing 5-me
165 ic pathways, and detailed information on the methylation status of each cytosine in any given genome
169 e that showed JARID2 binds to and alters the methylation status of histone H3 lysine 27 in the promot
170 date, a small number of enzymes that control methylation status of histones have been identified as c
182 ethod can reliably and accurately detect the methylation status of multiple target sites in each sing
183 ion content and a reduced correlation in the methylation status of neighboring cytosine--phosphate--g
185 ociated with decreases in both the redox and methylation status of neuronal cells, as defined by the
187 cessfully applied this model to evaluate DNA methylation status of normal human melanocytes compared
188 identified 10-base periodicities in the DNA methylation status of nucleosome-bound DNA and found tha
189 high-resolution microarray that detects the methylation status of over 25,000 CpG islands in the hum
192 entiation of epiblast cells to PGCs, how DNA methylation status of PGCLCs resembles the dynamics of 5
196 ethod, we characterized the landscape of the methylation status of repetitive elements, such as LINEs
197 sponse and characterization of molecular and methylation status of responders were secondary objectiv
199 function had a clear impact not only on the methylation status of RhoA but also RhoA activation and
200 ates with male infertility, we evaluated the methylation status of RHOX genes in sperm from a large c
202 iR-200b) and pyrosequencing to determine CpG methylation status of selected genes (Aph1a and Dkk4) in
207 RUNX2 gene transcription is regulated by the methylation status of specific CpG sites in the promoter
208 tudy aimed to determine the influence of the methylation status of specific CpG sites in the RUNX2 pr
209 drocytes is controlled by changes in the DNA methylation status of specific CpG sites of the proximal
210 U.S. population, to have effects on the DNA methylation status of specific genes in the placenta and
214 resistance was associated with an increased methylation status of the catalytic subunit of protein p
215 the insertion affects the maintenance of the methylation status of the CpG island of the modified bet
216 performed the first systematic survey of DNA methylation status of the CpG islands of the PEG3 (Pater
218 racterizing the functional links between the methylation status of the DNA and of two particularly im
220 associated variants are correlated with the methylation status of the FNDC1 gene (cg05678571, P=1.43
221 ry sclerosing cholangitis controls), and the methylation status of the four best performing markers w
224 Through its SET domain, WHSC1 regulates the methylation status of the histone H4 K20 residue and is
227 (BaP), a representative airborne PAH, on the methylation status of the IFNgamma and IL4 promoters in
230 e aims of this study were to compare the DNA methylation status of the IL6 promoter in rheumatoid art
231 oss of methylation at a CpG depends upon the methylation status of the immediately preceding CpG.
233 also observed significant differences in the methylation status of the insertion sites among MITE fam
235 i and performed manually-curated matching of methylation status of the key regulatory sequences (prom
236 f normal and tumor tissues revealed that the methylation status of the majority of CpG sites adjacent
240 y, however, the results indicated that the O methylation status of the OPS antigens was also affected
245 , phosphatase and tensin homolog (PTEN), and methylation status of the promotor region of the MGMT ge
247 he brain of Xenopus embryos, we analyzed the methylation status of the RASSF10-associated 5'-CpG isla
248 f these CpG sites, we also evaluated the DNA methylation status of the rDNA promoter in prostate canc
251 hout their juvenile phase can affect the DNA methylation status of their oocytes during gonad maturat
255 cAMP response elements, suggesting that the methylation status of these loci could serve as a mechan
258 ated CpG island, binds GLI2 depending on the methylation status of this CpG island, and physically in
259 rategy for parallel determination of the CpG-methylation status of thousands of Alu repeats, and a co
260 this method, we present data on the regional methylation status of two CpG clusters located in the EN
261 can improve over existing DMR detection (i) methylation statuses of nearby CpG sites are highly corr
262 9-2 with microsatellite instability and MLH1 methylation status (P < 0.001) and poor overall survival
264 icrosatellite instability status, CpG island methylation status, PTEN loss, EGFR expression, and copy
265 Analysis of the tumor suppressor gene p16 methylation status revealed a clear reduction in methyla
266 P53INP1, and DDAH1 genes at the level of DNA methylation status, RNA, and protein-level expression.
267 rd, TE insertions are distributed by age and methylation status, such that older, methylated TEs are
268 ncer iHMRs are more variable in sequence and methylation status than any other functional class, cons
269 We identified 195 genes with changes in methylation status that were significantly associated wi
270 Klf10 expression was primarily regulated by methylation status, the Klf10 promoter was examined by m
271 promoters, are the most dynamic in their DNA methylation status throughout development and differenti
272 n >/=5% and a 5-95% range >/=10%, we related methylation status to maternal pregnancy diet and to chi
273 r the quantitative measurement of global DNA methylation status using ultra-performance liquid chroma
274 d to capture PCR amplicons and determine the methylation status via fluorescence resonance energy tra
275 In multivariate analysis, melanoma AIM1 methylation status was a significant prognostic factor o
280 nts indicated that histone 3 lysine 9 (H3K9) methylation status was changed in elf6 and ref6 mutants,
282 as not affected, but global protein arginine methylation status was decreased (10-35%) in liver and b
287 The pooled results showed that MGMT promoter methylation status was significantly associated with an
288 st this hypothesis, DNA and protein arginine methylation status were assessed in liver, brain, heart,
291 features and outcomes based on PTEN promoter methylation status were then analyzed using SPSS and R.
292 c end points of correlative studies of COX-2 methylation status were time to recurrence, overall surv
293 on levels correlated inversely with promoter methylation status, whereas demethylation increased reel
294 etylation and, to a secondary degree, by its methylation status, which aided in the interpretation of
295 pG sites (CpG11 and CpG12 + 13) showed lower methylation status, which correlated with a strong assoc
296 pancreatic cancer is correlated with altered methylation status, which seems to be regulated by DNMT1
297 ybrid offspring, recapitulating the parental methylation status with nearly 100% fidelity, indicating
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