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1 total transcobalamin, total haptocorrin, and methylmalonic acid.
2 ular mitochondrial inhibitor and neurotoxin, methylmalonic acid.
3 th higher concentrations of homocysteine and methylmalonic acid and higher odds ratios for cognitive
6 e highest concentrations of homocysteine and methylmalonic acid and the lowest concentration of holot
7 eficiency who received treatment (15 of 21), methylmalonic acid and total homocysteine levels decreas
8 sorders characterized by the accumulation of methylmalonic acid and/or homocysteine in blood and urin
10 lasma total vitamin B-12, 3 studies measured methylmalonic acid, and 6 studies measured total homocys
11 rum and red blood cell folate, vitamin B-12, methylmalonic acid, and homocysteine concentrations amon
12 ean pretreatment values for serum cobalamin, methylmalonic acid, and homocysteine were, respectively,
13 the amount of B12 bound to TCII (holoTCII), methylmalonic acid, and homocysteine, in 128 healthy old
14 elevation of the metabolites, homocysteine, methylmalonic acid, and the ligand, transcobalamin II, i
15 serum concentrations of total vitamin B-12, methylmalonic acid, and total homocysteine are all effec
18 n status (defined by low cobalamin, elevated methylmalonic acid, and/or elevated homocysteine concent
19 ry results were significantly raised urinary methylmalonic acid compared with age-matched controls (p
20 n B-12 concentration < 148 pmol/L or a serum methylmalonic acid concentration > 210 nmol/L-the maximu
21 n B-12 concentration <148 pmol/L or a plasma methylmalonic acid concentration > or =210 nmol/L, the p
22 re, each 2-fold increment in homocysteine or methylmalonic acid concentration was associated with a d
30 ither vitamin B-12 or folate deficiency, and methylmalonic acid for detection of vitamin B-12 deficie
31 B-12 function (vitamin B-12 <200 pmol/L and methylmalonic acid >0.27 micromol/L) in the total group
35 using markers such as holotranscobalamin and methylmalonic acid, it has been found that cognition is
36 depression, had a significantly higher serum methylmalonic acid level and a nonsignificantly lower se
37 2 level less than 221 pmol/L and an elevated methylmalonic acid level; 2) a serum vitamin B12 level l
38 The higher serum cobalamin and lower serum methylmalonic acid levels at 4 months posttreatment in t
39 alization of elevated total homocysteine and methylmalonic acid levels may prevent the development of
41 tus [ie, plasma vitamin B-12 < 148 pmol/L or methylmalonic acid (MMA) > 210 nmol/L] with respect to a
42 racteristics of metabolic biomarkers such as methylmalonic acid (MMA) and holotranscobalamin II, whos
43 exists at which the relation between plasma methylmalonic acid (MMA) and SB-12 changes slope to diff
44 al, cognitive, routine diagnostic, and serum methylmalonic acid (MMA) and total homocysteine (tHcy) t
45 olate, serum vitamin B-12, homocysteine, and methylmalonic acid (MMA) concentrations in US children b
50 anscobalamin, total homocysteine (tHcy), and methylmalonic acid (MMA) were measured before and after
51 B(12) status, total homocysteine (tHcy) and methylmalonic acid (MMA), among adult participants in ph
52 min B-12, holotranscobalamin (holoTC), tHcy, methylmalonic acid (MMA), and folate with the use of lin
53 amin B-12, plasma total homocysteine (tHcy), methylmalonic acid (MMA), and holotranscobalamin into on
54 However, diagnostic algorithms using Cbl, methylmalonic acid (MMA), and homocysteine (HCys) measur
55 tus used in past NHANES--serum vitamin B-12, methylmalonic acid (MMA), and total homocysteine (tHcy)-
56 parison of baseline serum cobalamin, folate, methylmalonic acid (MMA), total homocysteine (tHcy), and
61 the use of vitamin B-12 than with the use of methylmalonic acid (MMA; 3-26% and 2-6%, respectively).
62 vels of cobalamin (normal, 200 to 900 pg/mL) methylmalonic acid (normal, 73 to 271 nmol/L), and homoc
63 ne, kynurenine, leucine, lysine, methionine, methylmalonic acid, ornithine, phenylalanine, proline, s
64 in the brain was evident from the increased methylmalonic acid (P<0.01-0.04), homocysteine (P<0.01),
65 , show failure to thrive, and show increased methylmalonic acid, propionylcarnitine, odd chain fatty
66 ene of Pseudomonas aeruginosa, which encodes methylmalonic acid semialdehyde dehydrogenase (MSDH) and
67 rum vitamin B-12, total homocysteine (tHcy), methylmalonic acid, serum folic acid, and 5-methyltetrah
68 ion test and measurement of homocysteine and methylmalonic acid, to cobalamin status has identified t
72 as associated with elevated homocysteine and methylmalonic acid, which were reduced by folate and vit
73 f folate, cobalamin, total homocysteine, and methylmalonic acid with cognitive performance at 2 occas
74 elderly population as documented by elevated methylmalonic acid with or without elevated total homocy
75 The use of serum vitamin B-12 and plasma methylmalonic acid would provide continuity with past NH
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