ライフサイエンスコーパス: methylthio

1 In the second method, the corresponding 3-(methylthio)-1,3-bis(het)aryl-2-propenones (prepared in s

2 ne ketones, by reacting in situ generated 3-(methylthio)-1,3-bis(het)aryl-2-propenones with arylhydra

3 butanoic acid, and 3-methylbutanoic acid; 3-(methylthio)-1-propanol; hexanoic acid; beta-damascenone;

4 rical 1,2,4,5-tetrazines, 3-methylsulfinyl-6-methylthio-1,2,4,5-tetrazine (4) and 3-(benzyloxycarbony

5 based on two side-chains of the A subunit, 3-methylthio-1,4-diphenyl-1H-1, 3,4-triazolium (MDT) was i

6 The versatility of the 4-methylthio-1-butyl phosphate/thiophosphate protecting gr

7 The thermolabile 4-methylthio-1-butyl phosphate/thiophosphate protecting gr

8 namely 2-methylthio-2-phenyl-1-ethanol and 2-methylthio-1-phenyl-1-ethanol.

9 methyl sulfide, 1-methylthio-propane, (Z)-1-methylthio-1-propene, and (E)-1-methylthio-1-propene, ha

10 opane, (Z)-1-methylthio-1-propene, and (E)-1-methylthio-1-propene, had not previously been associated

11 mide gave good yields of the corresponding 2-methylthio (12) and the 2-benzylthio (13) analogs.

12 2-azido (10), 2-amino (11), 2-thione (13), 2-methylthio (14a), and 2-benzylthio (14b) derivatives wer

13 ido-N-(4-((4-(4-(4-fluorophenyl)-1-methyl-2-(methylthio)-1H-imidazol-5-y l)pyridin-2-yl)amino)phenyl)

14 K3), 2-bromo-3-substituted-1H-1-indenones, 2-methylthio-1H-1-indenones, 3-butyne-1,2-dione, and 4-pen

15 The (N)-methanocarba-2-methylthio, 2-methylseleno, 2-hexyl, 2-(1-hexenyl), and

16 an accurate measurement of the level of S(6)-methylthio-2'-deoxyguanosine (S(6)mdG) in DNA of cells t

17 guanine (6-TG) in DNA can be converted to S6-methylthio-2-aminopurine (2-AP-6-SCH3) and 2-aminopurine

18 on involving organomagnesium reagents and (3-methylthio-2-azaallyl)stannanes with a Ni(0) catalyst pr

19 used, resulting in the formation of 5,6-bis-methylthio-2-chloro-3-(beta-D-ribofuranosyl)pyrazine and

20 nd human tumor cell lines, indicating that 4-methylthio-2-oxobutanoic acid acts as a negative regulat

21 f the penultimate salvage pathway compound 4-methylthio-2-oxobutanoic acid represses ODC levels in bo

22 P1 siRNA and the pharmacological inhibitor 4-methylthio-2-oxobutyric acid (MTOB) were used to abrogat

23 ce with the CtBP small-molecule inhibitors 4-methylthio-2-oxobutyric acid and 2-hydroxy-imino phenylp

24 duced two methylthiophenylethanols, namely 2-methylthio-2-phenyl-1-ethanol and 2-methylthio-1-phenyl-

25 protocol was developed, utilizing 2-amino-6-(methylthio)-4-(trimethylsilyl)nicotinonitrile as the key

26 t route to 2-phenyl/(2-thienyl)-5-(het)aryl/(methylthio)-4-functionalized thiazoles via one-step chem

27 beta-bis(methylthio)enamides to 2-phenyl-5-(methylthio)-4-substituted oxazoles.

28 Several cyclic 2-(methylthio)-5-amidofurans containing tethered unsaturati

29 A series of 2-(methylthio)-5-amidofurans containing tethered unsaturati

30 s desulfurization of the tetrabenzyl-6,6-bis(methylthio)-5-epi-valiolone and introduction of the deut

31 ceptors, whereas the P2Y1-specific agonist 2-methylthio-5'-adenosine diphosphate was, again, only eff

32 s II aldolase-like protein (Ald2) to form 2-(methylthio)acetaldehyde as an intermediate.

33 2-(Methylthio)acetaldehyde is reduced to 2-(methylthio)etha

34 se radiolysis of aqueous solutions of alpha-(methylthio)acetamide produced unexpectedly large quantit

35 ether derived from commercially available 2-(methylthio)acetic acid are most effective.

36 of neuronal NOS (nNOS) by (S)-2-amino-5-(2-(methylthio)acetimidamido)pentanoic acid (1): sulfide oxi

37 vailable 2-[2-bromo(het)aryl]-3-(het)aryl-3-(methylthio)acrylonitrile precursors with primary amines

38 0.6%), p-cresol (16.3%), adenine (12.5%), 2-(methylthio)adenine (15.5%), 5-hydroxybenzimidazole (1.8%

39 s-2-methyladenine, p-cresol, adenine, and 2-(methylthio)adenine.

40 pholipase C stimulation elicited by 10 nM 2-(methylthio)adenosine 5'-diphosphate (antagonist effect).

41 enzyme results in formation of 5'-deoxy-5'-(methylthio)adenosine and not 5'-deoxyadenosine.

42 the methyltransferase inhibitor 5'-deoxy(5'-methylthio)adenosine markedly enhanced SP-A expression i

43 MTA [5'-deoxy-5'(methylthio)adenosine], a pharmacological inhibitor of pr

44 abotropic receptor agonist), serotonin, or 2-methylthio-adenosine triphosphate (2mATP, a purinergic r

45 MTI arises through the deamination of methylthio-adenosine, a product of the polyamine biosynt

46 an P2Y12R in complex with the full agonist 2-methylthio-adenosine-5'-diphosphate (2MeSADP, a close an

47 affinity, and that of the agonists ADP and 2-methylthio-adenosine-5'-diphosphate, was reduced.

48 Superfusion of 2-methylthio-adenosine-5'-triphosphate (2-M-S-ATP) over qu

49 tion, and the corresponding ATP derivative 2-methylthio-adenosine-5'-triphosphate (2MeSATP) at 3.1 A

50 d then adenosine 5'-triphosphate (ATP) by 5'-methylthio-adenosine/AdoHcy nucleosidase (MTAN), adenine

51 P2Y(1) receptor stimulation with 2-methylthio ADP (2-MeSADP) induced activation of GIRK cur

52 The potency at P2Y(12) was 2-(methylthio)-ADP > 2-(methylthio)-ATP > ADP > ATP.

53 ors (adenosine 5'-(2-O-thio) diphosphate = 2-methylthio-ADP >/= 2-methylthio-ATP >> ADP > ATP) differ

54 t aggregation and secretion in response to 2-methylthio-ADP (2-MeSADP) and AYPGKF were diminished in

55 concentration (EC(50)) values for ADP and 2-methylthio-ADP (2-MeSADP) when compared with the wild-ty

56 rconversion, and an order of affinities of 2-methylthio-ADP (2MeSADP) > ADP = 2-methylthioATP = adeno

57 amma2 was stimulated by addition of either 2-methylthio-ADP (2MeSADP) or RGS4 and was markedly enhanc

58 An (N)-methanocarba-2-methylthio-ADP analogue displayed an EC(50) at the hP2Y(

59 Because changes in the potency of 2-methylthio-ADP and 2-(hexylthio)-AMP paralleled the chan

60 Both ADP and 2-methylthio-ADP caused a 3-fold increase in the level of

61 The P2Y1-selective agonist 2-methylthio-ADP increased [Ca(2+)]i in SGCs, and response

62 The P2Y(1) agonist 2-methylthio-ADP increased DBS, whereas the P2Y(1) antagon

63 1 was stimulated by ATP and UTP but not by 2-methylthio-ADP or adenosine.

64 In contrast, 2-methylthio-ADP promoted a substantial Ca(2+)(i) response

65 l. recently reported that, whereas ADP and 2-methylthio-ADP were agonists, ATP and 2-methylthio-ATP w

66 s incubated first with either ADP, ATP, or 2-methylthio-ADP were not labeled by 2-BrCH2(CO)2CH2S-ADP

67 P, but not 2',3'-O-(4-benzoyl)benzoyl-ATP, 2-methylthio-ADP, adenosine, or 5'-N-ethyl-carboxamidoaden

68 uid chromatographically purified ADP, ATP, 2-methylthio-ADP, and 2-methylthio-ATP resulted in rapid C

69 2Y(12) mutant retained normal responses to 2-methylthio-ADP, with an EC(50) of 0.15 +/- 0.04 nM.

70 However, 2-methylthio-ADP-induced intracellular Ca(2+) mobilization

71 was determined by measuring antagonism of 2-methylthio-ADP-stimulated phospholipase C (PLC) activity

72 kinetic study of the reaction of methyl beta-methylthio-alpha-nitrocinnamate (4-SMe) with morpholine,

73 Alkylation of this adduct gave the 2-methylthio and 2-benzylthio derivatives.

74 2-Methylthio and 2-chloro analogues were partial agonists

75 The (N)-methanocarba-2-methylthio and 2-chloromonophosphate analogues were full

76 The incorporation of (methylthio)aniline residues into a cage allowed for the

77 ntate ligands (e.g., 8-aminoquinoline and 2-(methylthio)aniline), has been investigated.

78 he auxiliaries such as, 8-aminoquinoline, 2-(methylthio)aniline, and N',N'-dimethylethane-1,2-diamine

79 rank order of agonist potency was ATP >/= 2 methylthio ATP > adenosine 5'-O-(3-thiotriphosphate) > a

80 ATP-gamma-S and 2-methylthio ATP (2-Me-S-ATP) were significantly less effe

81 Only ATP and 2 methylthio ATP were full agonists.

82 2-Methylthio ATP, alpha,beta-methylene ATP and ADP activat

83 tency at P2Y(12) was 2-(methylthio)-ADP > 2-(methylthio)-ATP > ADP > ATP.

84 O-thio) diphosphate = 2-methylthio-ADP >/= 2-methylthio-ATP >> ADP > ATP) differs from that of hP2Y(1

85 The P2Y purinoreceptor partial agonist, 2-methylthio-ATP (2-MeS-ATP), inhibits the expression of i

86 ceptor agonists in these neurons was ATP > 2-methylthio-ATP (2-MeSATP) > > alpha, beta-methylene ATP

87 s UTP and UDP, also inhibited IAC, whereas 2-methylthio-ATP (2-MeSATP) and CTP were completely ineffe

88 The potent P2Y1 receptor agonist 2-methylthio-ATP (2-MeSATP) had no activity in cells expre

89 e full P2Y receptor agonists ATP, ADP, and 2-methylthio-ATP (2MeSATP).

90 We found that ATP, 2-methylthio-ATP (MT-ATP) and UTP increase cAMP production

91 the analogues alpha,beta-methylene-ATP and 2-methylthio-ATP also inhibited K(+) currents.

92 00 microM) and UTP (1-100 microM), but not 2-methylthio-ATP or adenosine, stimulated mobilization of

93 ATP or 2-methylthio-ATP produced post-stimulus rebound responses

94 y purified ADP, ATP, 2-methylthio-ADP, and 2-methylthio-ATP resulted in rapid Ca2+ responses, with EC

95 he effects of alpha,beta-methylene-ATP and 2-methylthio-ATP were determined by measuring transmembran

96 nd 2-methylthio-ADP were agonists, ATP and 2-methylthio-ATP were weak antagonists in studies of the h

97 '-(beta, gamma-methylene)triphosphate, and 2-methylthio-ATP) stimulated Ca2+ influx and contraction t

98 hable, with the P2X receptor agonists ATP, 2-methylthio-ATP, 2' and 3'-O-(4-benzoylbenzoyl)-ATP, and

99 2-Methylthio-ATP, alpha,beta-methylene-ATP, and adenosine

100 ate), adenosine-5'-O-(1-thiotriphosphate), 2-methylthio-ATP, and 3'-O-(4-benzoyl)benzoyl-ATP were rou

101 Similar full agonist activities of ATP, 2-methylthio-ATP, and ADP were observed in human embryonic

102 sponse to the nucleotide receptor agonists 2-methylthio-ATP, ATP, ADP, and UTP, but not the kinin rec

103 oligonucleotide treatment also blocked the 2-methylthio-ATP-stimulated increase in contractile amplit

104 d is further decreased by cotreatment with 2-methylthio-ATP.

105 ited the rebound response caused by ATP or 2-methylthio-ATP.

106 y from stoichiometric reactions employing 2-(methylthio)benzaldehdye.

107 Starting from the synthesis of bromo-2-(methylthio)benzaldehydes, a series of functionalization,

108 We compare the conductance of 1,4-bis(methylthio)benzene with that of 2,3,6,7-tetrahydrobenzo[

109 methoxybenzene, 4-(dimethylamino)benzene, 4-(methylthio)benzene), di- and trivinylarenes, and methyle

110 re benzothiazole, 2-hydroxy-benzothiazole, 2-methylthio-benzothiazole, 2-amino-benzothiazole, and 2-t

111 een glycine and the novel ligand (S)-2-(N-(2-methylthio)benzylprolyl)aminobenzophenone in the presenc

112 Thus, 8-(methylthio)-BODIPY (1) undergoes an S(N)Ar-type reaction

113 [blocked by 1,4-diamino-2,3-dicyano-1,4-bis(methylthio) butadiene (U0126)], and therefore cAMP-depen

114 inhibitors, 1,4-diamino-2,3-dicyano-1,4-bis(methylthio)butadiene (U0126) and 2'-amino-3'-methoxyflav

115 nhibition by 1,4-diamino-2,3-dicyano-1,4-bis(methylthio)butadiene (U0126) of an HGF downstream kinase

116 (PD98059) or 1,4-diamino-2,3-dicyano-1,4-bis(methylthio)butadiene (U0126), two ERK kinase MAP inhibit

117 ttenuated by 1,4-diamino-2,3-dicyano-1,4-bis(methylthio)butadiene (U0126), which blocks the phosphory

118 K inhibitor [1,4-diamino-2,3-dicyano-1,4-bis(methylthio)butadiene (U0126)], whereas PAR2 effects were

119 DL-2-hydroxy-(4-methylthio)butanoic acid (HMTBA) is a source of dietary

120 After analysis, 4-(methylthio)butyl isothiocyanate was observed to be the m

121 ory notes, along with 4-mercaptobutyl and 4-(methylthio)butyl isothiocyanate, associated with typical

122 neous quantification of allyl, 3-butenyl, 4-(methylthio)butyl, benzyl and phenethyl isothiocyanates.

123 n and replacement of the N6-amino group with methylthio, chloro, or hydroxy groups greatly reduced th

124 dine C (ent-6) and gliocladin A (11), the di(methylthio) congener of bionectin A, are reported.

125 Here, we report 2-methylthio cyclic t6A (ms2ct6A), a novel derivative of c

126 in the methionine salvage pathway in which 5-methylthio-d-ribose (MTR) derived from 5'-methylthioaden

127 Instead, MTA is converted to 5-methylthio-d-ribose 1-phosphate (MTR 1-P) and adenine; M

128 lvage" pathway in Bacillus sp. and (2) the 5-methylthio-d-ribulose 1-phosphate (MTRu 1-P) 1,3-isomera

129 2-proton transfer reactions) that converts 5-methylthio-D-ribulose 1-phosphate to a 3:1 mixture of 1-

130 1-P) and adenine; MTR 1-P is isomerized to 1-methylthio-d-xylulose 5-phosphate (MTXu 5-P) and reducti

131 Methylthio-DADMe-immucillin-A (MT-DADMe-ImmA) is an 86-p

132 (MTA) was blocked by inhibition of MTAP with methylthio-DADMe-Immucillin-A (MTDIA), an orally availab

133 Methylthio-DADMe-immucillin-A is a pyrrolidine analogue

134 nd evaluation of the two diastereomers of 10-methylthio-DDACTHF (10R-3 and 10S-3) and related analogu

135 The methylamino, thio, and methylthio derivatives were neither active nor cytotoxic

136 ation of epidithio-, epitetrathio-, and bis-(methylthio)diketopiperazines from diketopiperazines has

137 ization of highly functionalized novel beta-(methylthio)enamides as the key step has been reported.

138 er carbonate-induced cyclization of beta-bis(methylthio)enamides to 2-phenyl-5-(methylthio)-4-substit

139 ty to carry out conversion of methanol to 2-(methylthio)ethanesulfonate (methyl-CoM).

140 In addition, the thioether 2-(methylthio)ethanol (MTE) coordinates 0.5 kcal/mol more s

141 dicate anaerobic ethylene production from 2-(methylthio)ethanol requires protein synthesis and that t

142 Ethylene induction experiments using 2-(methylthio)ethanol versus sulfate as sulfur sources furt

143 2-(Methylthio)acetaldehyde is reduced to 2-(methylthio)ethanol, which is further metabolized as a us

144 ide monomer with methyl-thioether moiety, 2-(methylthio)ethyl glycidyl ether (MTEGE), which enables t

145 A novel 2'-modification, 2'-O-[2-(methylthio)ethyl] or 2'-O-MTE, has been incorporated int

146 inverse agonist and 5'-adenylic acid, N-[2-(methylthio)ethyl]-2-[(3,3,3-trifluoropropyl)thio]-, mono

147 well-examined silver ionophore O,O' '-bis[2-(methylthio)ethyl]-tert-butylcalix[4]arene was monitored,

148 well-examined silver ionophore O,O' '-bis[2-(methylthio)ethyl]-tert-butylcalix[4]arene, the potassium

149 nts enhanced catalytic efficiency with 3-(2'-methylthio)ethylmalate approximately 100-fold and reduce

150 tIPMDH1-F137L) reduced activity toward 3-(2'-methylthio)ethylmalate by 200-fold, but enhanced catalyt

151 propylmalate dehydrogenase (IPMDH) and 3-(2'-methylthio)ethylmalate dehydrogenase catalyze the oxidat

152 tent oxidant to catalyze the attachment of a methylthio group (-SCH3) to C3 of aspartate 89 of protei

153 MiaB attaches a methylthio group at C2 of N(6)-(isopentenyl)adenosine, f

154 RimO attaches a methylthio group at C3 of aspartate 89 of protein S12, a

155 MTAN with MT-ImmA indicates a dimer with the methylthio group in a flexible hydrophobic pocket.

156 d from d-ribose (5-OH group instead of the 5-methylthio group in MTR) as well as of the natural DK-MT

157 The presence of the methylthio group in these oligosaccharides was establish

158 PNP.MT-ImmH.SO(4) shows that the hydrophobic methylthio group inserts into a hydrophobic region adjac

159 with bound MT-Imm-A also reveals that the 5'-methylthio group lies in a flexible hydrophobic pocket.

160 The replacement of the methylthio group of substituted methylthiobenzylidene Me

161 e enzyme responsible for the attachment of a methylthio group on the beta-carbon of Asp88 of the smal

162 that RimO(rcn) catalyzes the attachment of a methylthio group to a peptide substrate analogue that mi

163 articular lead compound (lactam 1) with an N-methylthio group was able to induce DNA damage and inhib

164 Analogs of lactam 1 in which the N-methylthio group was replaced with other organothio chai

165 Substitution of the 5'-methylthio group with a 5'-phenylthio group gives an equ

166 Substitution of the methylthio group with a p-Cl-phenylthio group gives a mo

167 stant of 172 pM, slightly weaker than the 5'-methylthio group.

168 poptosis, demonstrating requirement of the N-methylthio group.

169 tRNA(Lys), despite the presence of the bulky methylthio group.

170 pod, with each arm of the tripod ending in a methylthio group.

171 of an autocatalytic system: oxidation of the methylthio groups into sulfoxides make them electron-def

172 of 2-phenyl/(2-thienyl)-4-[bis(methylthio)/(methylthio)(het)arylmethylene]-5-oxazolo nes with alkoxi

173 philic ring-opening of newly synthesized 4-[(methylthio)hetero(aryl)methylene]-2-phenyl-5-oxazolone p

174 5'-Methylthio-Immucillin-A (MT-ImmA) is a slow-onset tight-

175 5'-Methylthio-Immucillin-A (MT-ImmA) is a transition state

176 Methylthio-immucillin-A (MT-ImmA) is an iminoribitol tig

177 5'-Methylthio-Immucillin-H (MT-ImmH) was designed to resemb

178 Moreover, TgPNP is insensitive to methylthio-immucillin-H (MT-ImmH), which inhibits PfPNP

179 5'-Methylthio-immucillin-H, a transition state analogue inh

180 ium enzyme, however, TgPNP cannot utilize 5'-methylthio-inosine (MTI).

181 When added to urine, synthetic (methylthio)methanethiol significantly enhances urine att

182 male urine; these neurons were activated by (methylthio)methanethiol, a potent, previously unknown se

183 The anion formed from the lithiation of 1-[(methylthio)methyl]-1H-benzotriazole 1 with n-BuLi adds t

184 Y 097, (S)-4-isopropoxycarbonyl-6-methoxy-3-(methylthio-methyl)-3,4-dihydroquinox alin-2(1H)-thione)

185 t] The rates of hydrolysis of alpha-R-alpha-(methylthio)methylene Meldrum's acids (8-R with R = H, Me

186 hyl, vinyl, phenyl, formyl, acetyl, methoxy, methylthio, methylsulfinyl, methylsulfonyl, sulfamoyl, a

187 Substitution of 4-methylthio, methylsulfinyl, or ethyl to a benzyl group a

188 ring-opening of 2-phenyl/(2-thienyl)-4-[bis(methylthio)/(methylthio)(het)arylmethylene]-5-oxazolo ne

189 ubstrate; the four other naturally occurring methylthio modifications have been observed on tRNA.

190 P) is involved in the salvage of adenine and methylthio moieties of 5'-deoxy-5'-methylthioadenosine,

191 ifies N(6)-isopentenyladenosine (i(6)A) to 2-methylthio-N(6)-isopentenyladenosine (ms(2)i(6)A) in tRN

192 LIAS, lipoic acid biosynthesis; CDK5RAP1, 2-methylthio-N(6)-isopentenyladenosine biosynthesis; CDKAL

193 nylmethyl-2-thiouridine (mcm(5)s(2)U(34)), 2-methylthio-N(6)-threonylcarbamoyladenosine (ms(2)t(6)A(3

194 N(6)-threonylcarbamoyladenosine (t(6)A) to 2-methylthio-N(6)-threonylcarbamoyladenosine (ms(2)t(6)A)

195 idine at position-34 (mcm(5)s(2)U(34)) and 2-methylthio-N(6)-threonylcarbamoyladenosine at position-3

196 )-isopentenyladenosine biosynthesis; CDKAL1, methylthio-N(6)-threonylcarbamoyladenosine biosynthesis;

197 es are present in the anticodon stem-loop--2-methylthio-N6-threonylcarbamoyladenosine at position 37

198 Salvadenosine, (1) a rare 5'-deoxy-5'-(methylthio) nucleoside, was isolated from the deep-water

199 ctions between O2 and 1,2-dihydroxy-3-oxo-5-(methylthio)pent-1-ene (acireductone) depending upon the

200 ir common substrates (1,2-dihydroxy-3-oxo-5-(methylthio)pent-1-ene and dioxygen) are derived from the

201 the same substrate, 1,2-dihydroxy-3-keto-5-(methylthio)pentene, depending exclusively on the nature

202 ls from three model compounds, tert-butyl 2-(methylthio)peroxybenzoate, 3-methylthiopropionic acid, a

203 toward various cancer cells, out of which 4-(methylthio)phenyl)(naphthalen-1-yl)methanone O-2-(diethy

204 N-(2-Bromo-5-(methylthio)phenyl)-N'- (3-ethylphenyl)-N'-methylguanidin

205 ate, trans-1,2,3,5,6,10-beta-hexahydro-6-[4-(methylthio)phenyl[pyrrolo-[2,1-a]i soquinoline ((+)-(11)

206 betic characterization of 1,2-dihydro-4-[[4-(methylthio)phenyl]methyl]-5-(trifluoromethyl)-3H- pyrazo

207 trans-1,2,3,5,6,10-beta-Hexahydro-6-[4-(methylthio)phenyl]pyrrolo-[2,1-a]- isoquinoline ([11C]Mc

208 eled trans-1,2,3,5,6,10-beta-hexahydro-6-[4-(methylthio)phenyl]pyrrolo-[2,1-a]-isoquin oline ([(11)C]

209 group, consisting of allyl methyl sulfide, 1-methylthio-propane, (Z)-1-methylthio-1-propene, and (E)-

210 le synthesis followed by methylation gave 2-(methylthio)pyrrole-2-(13)C.

211 ntial action of MTA phosphorylase (MtnP), 5-(methylthio)ribose-1-phosphate isomerase (MtnA), and an a

212 SAM) enzymes that catalyze the attachment of methylthio (-SCH3) groups to macromolecular substrates.

213 -emitting tracer, 62Cu-pyruvaldehyde bis (N4-methylthio- semicarbazone)(62Cu-PTSM) and PET.

214 be isolated but immediately underwent a 1,2-methylthio shift to form bicyclic lactams in 60-100% yie

215 idge cycloadducts underwent a subsequent 1,2-methylthio shift to form tricyclic lactams in high yield

216 the prokaryotic t6A nucleoside lacking the 2-methylthio substituent.

217 es, one stereoselective, for introducing the methylthio substituents of (+)-plectosphaeroic acid B we

218 and stereoselective introduction of the two methylthio substituents.

219 olecular Diels-Alder reaction of a 2-amido-5-methylthio-substituted furan containing a trans-pent-3-e

220 Explorative reactivity studies with the methylthio-substituted thiophene and pyrrole derivatives

221 nhibition is gained in the Immucillins by 5'-methylthio substitution which exploits the unique substr

222 n were prepared via the reaction of dimethyl(methylthio)sulfonium tetrafluoroborate (DMSTF) with beta

223 amido-substituted thioacetals with dimethyl(methylthio)sulfonium tetrafluoroborate (DMTSF) produces

224 n were prepared via the reaction of dimethyl(methylthio)sulfonium tetrafluoroborate (DMTSF) with beta

225 mma-thianyl carbonyl compounds with dimethyl(methylthio)sulfonium tetrafluoroborate (DMTSF).

226 dition of HOBr, HOCl, CH(3)SCl, and dimethyl(methylthio)sulfonium tetrafluoroborate (DMTSF)/NaN(3) wi

227 Treatment of cycloadduct 17 with dimethyl(methylthio)sulfonium tetrafluoroborate gave 2,5,6,7-tetr

228 disulfide in the presence of NBS gave the 4-methylthio-thiophenes as sole products.

229 selenyl-selenophenes, halo-thiophenes, and 4-methylthio-thiophenes, were selectively prepared in good

230 Bromo and methylthio were the optimal substituents for the R2 and