ライフサイエンスコーパス: mfERG

1 mfERG abnormalities were defined as z-scores of 2 or mor

2 mfERG amplitudes had no predictive power.

3 mfERG and fundus photographs were measured in both eyes

4 mfERG implicit times (IT) and amplitudes (AMP) were deri

5 mfERG implicit times tended to be more delayed at follow

6 mfERG implicit times were derived at 103 locations using

7 mfERG IT is a good predictor of DR onset, 1 year later,

8 mfERG ITs were not predictive of transient retinopathy.

9 mfERG responses represent postreceptor retinal activity.

10 mfERG z-scores were mapped onto fundus photographs, and

11 mfERGs and fundus photographs were obtained from 28 eyes

12 mfERGs of 16 individuals with glaucoma (POAG) and 18 nor

13 mfERGs showed loss of high-frequency components (HFCs) f

14 mfERGs were recorded from pigmented and albino rats by s

15 In infants (n = 23) and adults (n = 10), mfERG responses to both unscaled and scaled 61 hexagon a

16 terocular spatial correspondence of abnormal mfERG responses exists in adolescents with type 1 diabet

17 lected from a larger group based on abnormal mfERG amplitudes covering a diameter of 20 degrees or gr

18 ar correspondence of locations with abnormal mfERG AMP was also significant (P < 0.0002).

19 ar correspondence of locations with abnormal mfERG IT was significant for all 15 patients (P values <

20 No toxicity was detected by adding mfERG or SD-OCT.

21 The mfERG Amp, mfERG IT, SBP, and sex were together predictive of edema

22 threshold (P = 0.0003), BCVA (P = 0.01), and mfERG amplitude (P = 0.008).

23 preferred screening modalities, with FAF and mfERG less frequently ordered.

24 nd multifocal electroretinography (ffERG and mfERG), spectral-domain optical coherence tomography (SD

25 n funduscopic examination, visual field, and mfERG.

26 f different objective tests, such as MP1 and mfERG over a six-month follow-up.

27 rom the fovea (P < .05); abnormal SD OCT and mfERG values with respect to controls were found in corr

28 aminations, including fundus photographs and mfERG testing, were performed at each visit.

29 NFLT during one week and RNFL retardance and mfERG the next week.

30 RNFL retardance and mfERG were significantly reduced in the recordings just

31 Correspondence between SD-OCT thinning and mfERG abnormalities was shown in 67% of the eyes with ET

32 0-2 visual field mean deviation [VFMD]), and mfERG testing.

33 l associations between retinal thickness and mfERGs were not significant within any subject group or

34 e rod-mediated psychophysical thresholds and mfERGs were within normal limits.

35 The age-associated mfERG alterations are presented to emphasize the importa

36 r 1 year in the areas with abnormal baseline mfERG implicit times was approximately 21 times greater

37 pment of retinopathy in relation to baseline mfERG IT delays and additional diabetic health variables

38 Multivariate analyses yielded baseline mfERG IT, duration of diabetes, and blood glucose concen

39 than that in the areas with normal baseline mfERGs (odds ratio = 31.4; P < 0.001).

40 Associations between mfERG and age, duration, and diabetes control were exami

41 We conclude that there is a link between mfERG and SD-OCT measurements that increases with the pr

42 gitudinally whether the relationship between mfERG IT and diabetes control exists within individual a

43 presence of hydroxychloroquine as defined by mfERG testing.

44 hydroxychloroquine toxicity as identified by mfERG, and thus may be suitable surrogate tests.

45 rved cone photoreceptor function measured by mfERG amplitude and visual field sensitivity correlate w

46 nal abnormalities of the retina reflected by mfERG delays often precede the onset of new structural s

47 en with delays, in regions showing decreased mfERG responses and visual field sensitivity loss.

48 The 45 degrees mfERG stimulus included 103 hexagons, reversing between

49 ckness showed less relative loss than either mfERG or visual field sensitivity.

50 threshold, and multifocal electroretinogram (mfERG) amplitude and timing.

51 icits; (4) The Multifocal Electroretinogram (mfERG) and the Multifocal Visual Evoked Potential (mfVEP

52 f the standard multifocal electroretinogram (mfERG) are preferentially affected by diabetes mellitus.

53 The multifocal electroretinogram (mfERG) can provide objective corroboration for visual fi

54 velopment and: multifocal electroretinogram (mfERG) implicit time (IT) Z-score, mfERG amplitude (Amp)

55 al first-order multifocal electroretinogram (mfERG) implicit time (K1-IT) delays have proved to be im

56 Multifocal electroretinogram (mfERG) provides evidence of focal retinal dysfunction re

57 commonly used multifocal electroretinogram (mfERG) stimuli, as well as the standard transient patter

58 gical success, multifocal electroretinogram (mfERG), and histopathologic analyses performed between 3

59 y evidenced by multifocal-electroretinogram (mfERG) and microperimetry (MP1) after treatment with Ocr

60 fields (VFs), multifocal electroretinograms (mfERG), and spectral-domain optical coherence tomography

61 Multifocal electroretinograms (mfERGs) and psychophysical assessments of acuity and lum

62 Multifocal electroretinograms (mfERGs) were obtained from 62 normally sighted subjects

63 and scotopic multifocal electroretinograms (mfERGs) were recorded.

64 derived from multifocal electroretinograms (mfERGs).

65 cone-mediated multifocal electroretinograms (mfERGs).

66 (SD-OCT) and multifocal electroretinography (mfERG) along with visual fields.

67 l studies by multifocal electroretinography (mfERG) evaluated neurodysfunction, and structural measur

68 y (OCT), and multifocal electroretinography (mfERG) were performed at baseline and 12 time points (1-

69 SD-OCT), and multifocal electroretinography (mfERG) were performed at various intervals.

70 sual fields, multifocal electroretinography (mfERG), and contrast sensitivity were measured in all su

71 up including multifocal electroretinography (mfERG), spectral-domain optical coherence tomography (SD

72 ce (FAF), or multifocal electroretinography (mfERG).

73 testing, and multifocal electroretinography (mfERG).

74 ardance, and multifocal electroretinography (mfERG).

75 The revised guidelines, emphasizing mfERG, SD-OCT, or FAF, raised screening cost without imp

76 survival were assessed with multifocal ERG (mfERG) and histology 1 week after PDT.

77 R development and 7 factors: multifocal ERG (mfERG) implicit time (IT) Z-score, sex, diabetes duratio

78 g electroretinography (ERG), multifocal ERG (mfERG), perimetry, optical coherence tomography (OCT), f

79 In the four treated eyes mfERG revealed an increased foveal peak response over th

80 es:BEST1 mutations, SD-OCT and FAF findings, mfERG amplitudes, prevalence estimate of Best disease.

81 -adapted flash ERG, 103-hexagon global-flash mfERG (MFOFO), and static perimetry.

82 ns between regional measures of global-flash mfERG, RNFLT, and VS suggest that LFC RMS amplitude prov

83 asured locally by OCT is not a surrogate for mfERGs in early diabetes.

84 mfERG, a model of the waveform of the human mfERG is proposed.

85 The waveform of the human mfERG most closely resembles the rhesus monkey's mfERG a

86 In comparison, the human mfERG resembles the monkey's mfERG after reduction of in

87 Damage was identified by OCT imaging, mfERG testing, and, in 1 case, visual field testing.

88 ection before a second round of PDT improved mfERG responses and retinal structure.

89 th ETDRS 20-35 presented no abnormalities in mfERG or SD-OCT.

90 function showed little or no disturbance in mfERG recordings.

91 These included mfERGs for three different stimuli: a standard fast m-se

92 The infants' mfERG responses indicated immaturities of processing in

93 Local mfERG implicit times were measured and their z-scores we

94 implicit times (ITs) were derived from local mfERG response waveforms, and Z-scores were calculated.

95 The inclusion of local mfERG implicit times allowed the model to identify the s

96 Mean mfERG IT was significantly longer in the patients compar

97 Cone-mediated mfERG measures of amplitude scale and time scale were ab

98 em visual field thresholds and cone-mediated mfERGs.

99 thresholds (visual fields) and rod-mediated mfERGs.

100 uency bands were discriminated in the monkey mfERG: fast OPs, with a peak frequency of 143 +/- 20 Hz,

101 Monkey mfERGs were obtained before and after inner retinal resp

102 The monkey mfERGs were recorded before and after injections of phar

103 ose (BG) concentration, HbA1c, and monocular mfERG were performed on 115 adolescent patients (mean ag

104 Noninvasive monocular mfERGs were recorded in anesthetized albino (Sprague-Daw

105 ponding to markedly reduced or nonrecordable mfERG responses.

106 l-inner plexiform layer thickness and normal mfERG findings.

107 The longitudinal analysis of mfERG data shows a significant increase of N1 and P1 amp

108 r loss in the low-frequency (<25 Hz) band of mfERG.

109 e P50 component and substantial reduction of mfERG high-frequency components.

110 The pooled sensitivity and specificity of mfERG were 90% (95% confidence interval [CI], 0.62-0.98)

111 evaluate the sensitivity and specificity of mfERG when compared with automated visual fields (AVFs),

112 ed a search for records reporting the use of mfERG for screening CQ/HCQ retinopathy in MEDLINE (PubMe

113 ropriate normative data in interpretation of mfERGs.

114 amplitude (AMP) and P1 implicit time (IT) of mfERGs within the central approximately 20 degrees diame

115 19) and unaffected (n = 38) groups based on mfERG criteria.

116 icted by using a multivariate model based on mfERG implicit time.

117 The effects of experimental glaucoma on mfERG were assessed in the frequency domain.

118 In 58% of patients, mfERG abnormalities were present in the absence of visib

119 Photopic mfERGs were recorded with Dawson-Trick-Litzkow (DTL) fib

120 ference test, patients with a false-positive mfERG result received higher HCQ cumulative doses (1068

121 with a normal or subnormal ERG, but reduced mfERG.

122 nd the combination of BDNF and CNTF reducing mfERG responses.

123 Across all ring eccentricities, relative mfERG amplitude and relative visual field sensitivity we

124 Commonly reported mfERG methods were used to quantify the responses: peak-

125 Within each patient with RP, mfERG amplitude for each circle/annulus was highly corre

126 G most closely resembles the rhesus monkey's mfERG after administration of TTX.

127 ison, the human mfERG resembles the monkey's mfERG after reduction of inner retinal contributions.

128 g the inner retinal influences, the monkey's mfERG is mainly composed of ON- and OFF-bipolar contribu

129 The monkey's mfERG is shaped by large contributions from ON- and OFF-

130 the pharmacologic dissection of the monkey's mfERG, a model of the waveform of the human mfERG is pro

131 moves a large contribution from the monkey's mfERG, but it does not remove all inner retinal influenc

132 Static automated perimetry (SAP), mfERGs, and mfVEPs were obtained from 15 individuals see

133 tinogram (mfERG) implicit time (IT) Z-score, mfERG amplitude (Amp) Z-score, sex, diabetes duration, d

134 The slow-sequence mfERG summed over the stimulated area looked similar to

135 st easily detected using the slowed-sequence mfERG.

136 Photopic slow-sequence mfERGs were recorded from anesthetized adult macaque mon

137 component changes were examined using the sf-mfERG in diabetic subjects with and without diabetic ret

138 ut NPDR can be detected and mapped by the sf-mfERG.

139 Slow-flash multifocal electroretinograms (sf-mfERGs) were recorded from the central 45 degrees, and s

140 Later components (P1 and N2) of the local sf-mfERGs were not preferentially affected by diabetes.

141 ents and the amplitude of the first-order sf-mfERGs were examined.

142 The slow-flash (sf-)mfERG stimulates with flashes separated by dark periods,

143 Multivariate analysis showed mfERG IT to be predictive for DR development in a zone a

144 tern deviation plots), SD-OCT, and sometimes mfERG or fundus autofluorescence.

145 The summed mfERG waveform, including OPs, was shaped mainly by the

146 mfERG was verified against AVF suggests that mfERG may have the ability to detect cases of toxicity e

147 The mfERG Amp, mfERG IT, SBP, and sex were together predicti

148 The mfERG low-frequency components were slightly larger than

149 The mfERG P1 amplitude was more sensitive than the P1 implic

150 The mfERG stimulus was comprised of 103 hexagons, and subten

151 The mfERG waveforms were consistent with inner but not outer

152 and higher-order kernels resulting from the mfERG contain detailed information regarding the nonline

153 f 35 retinal zones were constructed from the mfERG elements and each was graded for DE.

154 nning 45 degrees , were constructed from the mfERG stimulus elements.

155 Reductions of the mfERG amplitude, followed by varying degrees of recovery

156 eased amplitudes relative to baseline of the mfERG high-frequency components (-65%, P = 0.018), the P

157 llow-up examination was modeled based on the mfERG implicit time z-score for the zone and other candi

158 eld, photopic ERG most closely resembles the mfERG responses to stimulation of peripheral regions.

159 After administration of TTX, the mfERG is further modified by the addition of NMDA.

160 In these eyes, 70% of the mfERGs in areas of new retinopathy had abnormal implicit

161 At each time, mfERGs were recorded from 103 retinal locations, and fun

162 nontreated area showed amplitude and timing mfERG deficits, which underwent gradual (but not complet

163 Retinal thickness was compared to mfERGs to determine spatial associations.

164 Together mfERG, SBP, and sex are good predictors of local edema i

165 We used mfERG test parameters as a gold standard to divide parti

166 ted the feasibility and limitations of using mfERG to assess topographical changes in the rat retina.

167 tive model was formulated with the variables mfERG implicit time, duration of diabetes, presence of r

168 p compared with the true-negative group when mfERG was verified against AVF suggests that mfERG may h

169 lipsoid zone in the central 7 degrees, while mfERG response amplitudes were reduced only in the centr