ライフサイエンスコーパス: mice exhibited

1 y reduce metastasis, we found that thrombopoietin-deficient mice exhibited a 90% relative decrease in megakaryocytes, yet

2 MiR-211 knockout (-/-) mice exhibited a progressive cone dystrophy accompanied by si

3 Livers from Alb/SND1 mice exhibited a relative increase in inflammatory markers an

4 compared with wild-type infected mice, CD151-null infected mice exhibited a significant reduction in virus titer and imp

5 Upon exposure to UVB irradiation, fat-1 transgenic mice exhibited a significantly reduced epidermal hyperplasia,

6 betaENaC MG KO mice exhibited a striking age-dependent, female-predominant M

7 ed counterparts, ReninAAV-treated type 1 diabetic Akita/129 mice exhibited a substantial increase in albumin-to-creatinin

8 MiR-142(-/-) mice exhibited abnormal abscess formation at S. aureus-infect

9 Arid1b-heterozygous mice exhibited abnormal cognitive and social behaviors, which

10 e-specific double-knockout Smad1(fl/fl);Smad5(fl/fl);Cre(+) mice exhibited approximately 90% transferrin saturation and m

11 -related gene expression, whereas Tsc1 conditional knockout mice exhibited changes in genes regulating TGF-beta/BMP/FGF s

12 Polyclonal Bim(-/-) and Bim(-/-)Nur77(-/-) mice exhibited comparable accumulation of high-affinity signa

13 BTBR Lep(ob) mice exhibited diabetic kidney disease.

14 STZ-induced diabetic mice exhibited distinct cardiac dysfunction, dampened intrace

15 atient-derived xenograft tumours growing in immunodeficient mice exhibited enhanced hypoxia compared to the original tumo

16 Ripk3(-/-) mice exhibited enhanced mortality compared to wild-type (WT)

17 Here, we reported that myeloid cell-specific Nrp1-deficient mice exhibited enhanced susceptibility to cecal ligation and

18 Mutant mice exhibited fewer suppressive Tregs in the injured myocard

19 In addition, ANX - A1 (-/-) mice exhibited greater expansion of HSPCs and altered pattern

20 Alveolar macrophages from female mice exhibited greater expression of the IL-4Ralpha and estro

21 stal convoluted tubules (DCTs): Ksp-cre;Pth1r(fl/fl) Mutant mice exhibited hypercalciuria and had lower serum calcium and

22 Furthermore, calpain-1 KO mice exhibited impairment in fear memory extinction to tone p

23 Kmo(-/-) mice exhibited impairments in contextual memory and spent les

24 long-term improvement in functional outcome, as DHC-treated mice exhibited improved behavioral recovery at one month post

25 with vehicle-injected mice, both iPSC- and iPSC-EV-treated mice exhibited improved left ventricular function at 35 d aft

26 Remarkably, testing of myocardial tissue from Mc4r-/- mice exhibited increased ADP stimulated respiratory capacity.

27 ction, TLR2 knockout (TLR2KO)-->TLR2KO bone marrow chimeric mice exhibited increased bacterial burden, disorganized accum

28 During pneumococcal pneumonia, Miwi2-deficient mice exhibited increased expression of inflammatory mediators

29 Chow-fed GLP-1RKD(DeltaNkx2.1cre) mice exhibited increased food intake and energy expenditure w

30 Tumors from the Hic-5(-/-);PyMT mice exhibited increased latency and reduced growth, with few

31 Tfeb (DeltaIEC) mice exhibited lower levels of lipoprotein ApoA1 expression,

32 mdx-knockout mice exhibited lower muscle force/endurance as well as increa

33 Macrophages in fibrotic mice exhibited M2-preponderant activation, which was not the

34 841K) ) for the mutation in each model, MYH9(E1841K/E1841K) mice exhibited mildly increased albuminuria in response to hi

35 Furthermore, IL-4-stimulated macrophages from female mice exhibited more transcriptionally active histone modifica

36 On the other hand, the Igf1r-deficient mice exhibited no AHR, and a selective decrease in blood and

37 whereas hepatocyte and macrophage Bmp6 conditional knockout mice exhibited no iron phenotype.

38 Unexpectedly, Syn-2 knockout mice exhibited paradoxical superior glucose homeostasis resul

39 The Reep6-/- mice exhibited progressive photoreceptor degeneration from P2

40 After high-fat feeding, Gpr119(-/-) mice exhibited reduced fat mass, decreased levels of circulat

41 In vivo, these mice exhibited reduced severity of experimental autoimmune en

42 cient common gamma chain-deficient stem cell factor (huNSG) mice exhibited robust engraftment with functional human T and

43 d tumors outside the primary tumor microenvironment in nude mice, exhibited signatures of immune evasion, increased stemn

44 HD mice exhibited significantly altered functional connectivity

45 Compared to the urethane treated ND-fed mice, the HCD-fed mice exhibited significantly decreased lung tumor multiplicit

46 controls, striatal synaptosomes isolated from young mutant mice exhibited significantly lower dopamine uptake after rote

47 CX3CR1-deficient mice exhibited significantly lower expression of HMOX-1 in th

48 On a normal salt diet, dKO and single-knockout mice exhibited similar activation of the renin-angiotensin-al

49 These mice exhibited unchanged antihyperalgesia indicating a supras

50 Upon cyclosporin A treatment, Nupr1-deficient mice exhibited worse renal tubular lesions than wild-type mic