ライフサイエンスコーパス: microRNA

1 irect target of miR-708, a tumor-suppressive microRNA.

2 djustment and visual inspection of candidate microRNAs.

3 vel microRNAs and characterizing features of microRNAs.

4 action of the differences may be mediated by microRNAs.

5 ng liposomes for the functional knockdown of microRNAs.

6 nt expression of muscle structural genes and microRNAs.

7 categories that could be related to specific microRNAs.

8 ased hepatic expression of tumor-suppressive microRNAs.

9 ostic and therapeutic use of smoking-related microRNAs.

10 Here, we show that microRNA-1 (miR-1), a member of the muscle-specific micr

11 MicroRNA 122 (MIR122) is expressed only in the liver, wh

12 The hepatocyte specific microRNA 122 (MIR122) regulates hepatocyte differentiati

13 MicroRNA-122 (miR-122) is abundant in the liver and invo

14 that have either enhanced liver specificity (microRNA-122 [miR-122]) or provide mechanistic insights

15 01, an N-acetylgalactosamine-conjugated anti-microRNA-122 oligonucleotide, resulted in a significant

16 MicroRNA-122, an abundant and conserved liver-specific m

17 Here, we report that high levels of microRNA-128-3p (miR-128-3p) is key to concomitant devel

18 ion in prostate cancer cells by upregulating microRNA-128.

19 In this study, we show that microRNA-134-5p (miR-134) can regulate Sabin-1 replicati

20 MicroRNA-146a (miR-146a) has been identified as a critic

21 ound that, under proinflammatory conditions, microRNA-146a (miR-146a) is transcriptionally upregulate

22 Altogether we show that the microRNA-146a and its target DLST are important metaboli

23 tic knockdown or pharmacological blockade of microRNA-146a blunted the hypertrophic response and atte

24 Overexpression of microRNA-146a in cardiomyocytes provoked cardiac hypertr

25 tive metabolism were partially maintained in microRNA-146a knockout mice.

26 Mechanistically, microRNA-146a reduced its target DLST-the E2 subcomponen

27 In human lung epithelial cells, the microRNA-150 (miR-150) was identified to interact with F

28 ll homeostasis through the regulation of BIC/microRNA 155 (miR-155) and its target, suppressor of cyt

29 microRNA-155 (miR-155) is specifically overexpressed in

30 MicroRNA-155 (miR-155) regulates antitumor immune respon

31 l and neuropathic pain are controlled by the microRNA-183 (miR-183) cluster in mice.

32 The association of uc.173 with microRNA 195 (miRNA195) was determined by RNA pull-down

33 rray of noncoding RNAs, ranging in size from microRNA (20-23 nucleotides) to long noncoding RNA (lncR

34 a double-negative feedback loop between the microRNA-200 (miR-200) family and ZEB1, but the precise

35 Down-regulation of microRNA-200a expression in melanoma cells is associated

36 Conversely, low microRNA-200a expression in metastatic melanoma cells re

37 Furthermore, microRNA-200a expression is epigenetically modulated by

38 We propose that microRNA-200a functions as a "cell cycle brake" that is

39 Levels of microRNA 21 (MIR21 or miRNA21) are increased in CCAs.

40 In previous studies we identified microRNA-21 as a STAT3 target gene with strong anti-apop

41 Melanocyte-enriched microRNA-211, a known metabolic switch in nonpigmented m

42 microRNA-28 (miR-28) is a GC-specific miRNA whose expres

43 The microRNA-29 (miR-29) family has been found to prevent ex

44 amined the effects on levels and activity of microRNA-34a (MIR34A) in CRC cells.

45 ed on such strong rationale, we encapsulated microRNA-34a in our well-established Hyaluronic-Acid nan

46 Here we show that microRNA-34a provides homoeostatic control of CD1c(+) DC

47 We demonstrate here that microRNA-9 (miR-9) modified BMSCs (pri-miR-9-BMSCs) can

48 hile simultaneously inhibiting expression of microRNA-9, which targets the PTX3 transcript.

49 Here we demonstrate that microRNA-92a (miR-92a) is enriched in podocytes of patie

50 The microRNA-99 (miR-99) family comprises a group of broadly

51 MicroRNAs, a group of small, noncoding RNAs that post-tr

52 ve; our findings show that the mir-35 family microRNAs act in the early embryo to function as a devel

53 ides a sensitive and quantitative measure of microRNA activity in vivo and also identifies novel regu

54 The expression of several microRNAs also differed between disease conditions.

55 N function impacts the action of a pertinent microRNA and its mRNA target in MNs.

56 Our previous genome-wide microRNA and mRNA transcriptome analyses suggest a key r

57 gnal along with distinct changes in exosomal microRNA and proteomic profiles prior to appearance of h

58 We identified 46 microRNAs and 1,559 genes that were differentially expre

59 lity and rigor of miRvial in detecting novel microRNAs and characterizing features of microRNAs.

60 redicted targets of differentially expressed microRNAs and differentially expressed mRNAs revealed en

61 erous publications have suggested that RNAs (microRNAs and incomplete mRNAs) undergo transfer via ext

62 atasets involving numerous splicing factors, microRNAs and m6A RNA methylation.

63 modulate and assess the in vivo function of microRNAs and mRNAs in TEMCs.

64 irs were identified within these deregulated microRNAs and mRNAs, which consisted of 17 unique protei

65 ith different sets of RNA regulators such as microRNAs and RNA-binding proteins.

66 pression of extracellular vesicle-associated microRNAs and their diagnostic potential in plasma sampl

67 gene expression, DNA methylation, noncoding microRNA, and copy number variation data available from

68 al interaction between miR-574-3p, a CA-rich microRNA, and hnRNP L.

69 MicroRNAs are essential in many cellular processes.

70 MicroRNAs are important genetic regulators in both anima

71 MicroRNAs are key regulators of vascular smooth muscle c

72 1034 1034 References 1034 Copper (Cu) microRNAs are upregulated by Cu deficiency and mediate t

73 Multiple mRNA targets of the miR-290 cluster microRNAs are upregulated.

74 the process of identifying 248 mRNAs and 15 microRNAs as differentially expressed, we also identifie

75 To identify circulating microRNAs associated with acute IS, determine their temp

76 Ever since miR-H2's discovery as a viral microRNA bearing complete sequence complementarity to th

77 o form in trans when one RNA, for instance a microRNA binds to a second structured RNA, such as a mRN

78 osha (Drosha (cKO)), an enzyme essential for microRNA biogenesis, leads to anemia and death.

79 g growth of root hairs mostly independent of microRNA biogenesis.

80 petunia floral whorls, in parallel with the microRNA BLINDBEN belongs to the TOE-type AP2 gene famil

81 via the sensitive label-free detection of a microRNA cancer biomarker (miR-16) in blood plasma.

82 r, overexpression or downregulation of these microRNAs causes no significant variations in uc.339 lev

83 ere we demonstrate for the first time that a microRNA component of this region-miR-383-is frequently

84 k aimed at filling this gap by assessing the microRNA content in EVs released upon in vitro T cell re

85 The abundance of several microRNAs correlated with indexes of renal function.

86 The identified microRNAs could be developed as biomarkers of kidney dis

87 ved pathways, together with their regulatory microRNAs could serve as promising and sought-after biom

88 94 and let-7c were introduced into otherwise microRNA-deficient Dgcr8 knockout mouse embryonic stem c

89 Levels of all 3 microRNAs depended on platelet numbers in a platelet spi

90 fically, we find that SERRATE functions in a microRNA-dependent manner to inhibit hair cell fate, whi

91 with a miR-139-5p mimetic.Significance: The microRNA described in this study offers a potentially us

92 of oncomiR-1 reveal that most of its primary microRNA domains are suboptimal substrates for Drosha-DG

93 associated herpesvirus (KSHV) encodes 12 pre-microRNAs during latency that are processed to yield 25

94 epression is mediated by miR-33, an intronic microRNA encoded within the SREBP loci, the expression o

95 98 human needle kidney biopsy specimens for microRNA expression analysis using deep sequencing.

96 Here we present a parallel study of mRNA and microRNA expression during oral siphon (OS) regeneration

97 Previous analyses of microRNA expression in human kidneys, however, were limi

98 R deficiency increased the levels of certain microRNA expression in Th17 cells; for example, miR-466i

99 Chagas heart disease by integrating gene and microRNA expression profiling data from hearts of T. cru

100 tablish the landscape of human cell-specific microRNA expression.

101 om 461 samples into a coordinated catalog of microRNA expression.

102 e results comparing miRvial and six existing microRNA finding methods on six model organisms, Mus mus

103 Of these, miR-30b/d was the most significant microRNA for the follow-up analyses, which also showed l

104 on to proteins, the virus encodes >40 mature microRNAs for which the functions remain largely unknown

105 MicroRNAs form an essential class of post-transcriptiona

106 lts suggest decreased SMN leads to defective microRNA function via MEL-46 misregulation, followed by

107 Further exploration of Cu-microRNA functions that account for the cell-to-cell mob

108 risk allele facilitating the assembly of the microRNA-guided Argonaute 1 complex and gene silencing.

109 formation of a complex between the paRNA and microRNA-guided Argonaute 1 that, together, recruit SUV3

110 The two microRNAs had opposing effects on transcriptional hetero

111 Aberrant expression of microRNAs hae been shown to be closely associated with g

112 MicroRNAs have emerged as attractive biomarker candidate

113 MicroRNAs have emerged as important regulators of glucos

114 MicroRNAs have recently emerged as important regulators

115 differential glomerular expression of select microRNAs in a second cohort of patients with DN (n=19)

116 ular beacons can also be employed to inhibit microRNAs in a specific manner.

117 Experimental validation of several novel microRNAs in C. reinhardtii that were predicted by miRvi

118 However, the in vivo functions of specific microRNAs in controlling mammary stem cell (MaSC) activi

119 To better understand the roles of microRNAs in glial function, we used a conditional delet

120 -124 knockdown revealed a key role for these microRNAs in neuronal organization during planarian brai

121 This study implicates microRNAs in the pathogenesis of AA.

122 used as a valuable tool for the detection of microRNAs in vivo, molecular beacons can also be employe

123 ression of numerous Treg signature genes and microRNAs involved in Treg homeostasis and suppressive p

124 cells, providing an explanation for why this microRNA is targeted in HPV-positive cells.IMPORTANCE We

125 Depletion of the let-7 family of microRNAs is a primary cause of this defect, as it leads

126 Mechanistically, the expression of these microRNAs is positively regulated by p53 and negatively

127 ult, Cyclin E2, a direct target of all these microRNAs is upregulated, promoting cancer growth and mi

128 s with a phosphomutant DGCR8, which restored microRNA levels but did not rescue the exit from pluripo

129 Overload-induced changes in microRNA levels regulate SIRT1 and insulin-like growth f

130 monstrate that tRFs are bona-fide regulatory microRNA-like small RNAs involved in the regulation of g

131 minor strand (passenger) microRNAs of known microRNA loci and 495 novel putative microRNA loci.

132 f known microRNA loci and 495 novel putative microRNA loci.

133 analyzed, on a transcriptome-wide scale, how microRNA-mediated repression modulates the associations

134 EB1 stimulated Golgi compaction and relieved microRNA-mediated repression of the Golgi scaffolding pr

135 memory mechanism by which learning reverses microRNA-mediated silencing of the novel plasticity prot

136 lves production of either the anti-migratory microRNA miR-198 or the pro-migratory follistatin-like 1

137 ation in vitro and in vivo, and identify the microRNA miR-21 as a long-term memory keeper of the fibr

138 We found that the microRNA miR-31 was strongly induced by activation of th

139 or allele of rs322931 predicts expression of microRNAs miR-181a and miR-181b in human brain and blood

140 We examined HCV entry in HepG2/microRNA (miR) 122/CD81 cells, which support entry and r

141 rast, we found that SMA astrocytes increased microRNA (miR) production and secretion compared to cont

142 lls; their cargo includes proteins, mRNA and microRNA (miR) that can be transferred to recipient cell

143 MicroRNA (miR)-155 has recently been described to regula

144 we report that dynamic changes in forebrain microRNA (miR)-211 in the mouse brain shift the threshol

145 Here, we identify microRNA (miR)-337-3p as a regulator of liver developmen

146 asion, and glycolysis through suppression of microRNA (miR)-455-3p.

147 reased MEL-46 levels also restored perturbed microRNA (miR-2) function in smn-1(lf) animals.

148 y response essential for functional immunity.MicroRNAs (miR) are important regulators of gene transcr

149 ong non-coding RNA MIR100HG and two embedded microRNAs, miR-100 and miR-125b, were overexpressed in t

150 g or by pro-inflammatory and pro-atherogenic microRNAs, miR-155 and miR-33.

151 In addition, we applied the methods to both microRNA (miRNA) and messenger RNA (mRNA) sequencing dat

152 One such example is the interaction between microRNA (miRNA) and messenger RNA (mRNA), whose deregul

153 We explored the possibility of using urinary microRNA (miRNA) as a non-invasive biomarker for hyperte

154 RNA pathways, predicted over 2600 conserved microRNA (miRNA) candidates, and performed phylogenetic

155 Studies have showed that abnormal microRNA (miRNA) expression can affect CRC pathogenesis

156 ence of a chlamydial population dictates the microRNA (miRNA) expression profile of the host, which,

157 ring SAR induction, we examined mRNA levels, microRNA (miRNA) expression, and their regulatory mechan

158 Recent studies illuminated a novel role of microRNA (miRNA) in the competing endogenous RNA (ceRNA)

159 and OR logic gates that respond to synthetic microRNA (miRNA) inputs.

160 We performed microRNA (miRNA) profiling in 318 serum samples from 69

161 The effects of microRNA (miRNA) regulation on the genetic programs unde

162 Each microRNA (miRNA) represses a web of target genes and, th

163 ght to comprehensively profile pediatric AML microRNA (miRNA) samples to identify dysregulated genes

164 we report a sensing scheme for detection of microRNA (miRNA) using electrocatalytic amplification (E

165 mical detection of a breast cancer biomarker microRNA (miRNA), mir-21 was achieved via electropolymer

166 MicroRNA (miRNA)-mediated RNA interference regulates man

167 h an adipose-tissue-specific knockout of the microRNA (miRNA)-processing enzyme Dicer (ADicerKO), as

168 rlier study that conditional deletion of the microRNA (miRNA)-processing enzyme Dicer from nephron pr

169 lopment of GA has been linked to loss of the microRNA (miRNA)-processing enzyme DICER1 in the mature

170 ompartments of the neuron, for both mRNA and microRNA (miRNA).

171 MicroRNAs (miRNA) in cerebrospinal fluid were amplified

172 , leads to release of cellular RNA including microRNA(miRNA) into the circulation and extracellular (

173 Modulation of the expression and activity of microRNA (miRNAs) represents an emerging translational f

174 In this study, we aimed to use microRNAs (miRNAs) - which are critical regulators of si

175 MicroRNAs (miRNAs) and heterogeneous nuclear ribonucleop

176 Regulation by microRNAs (miRNAs) and modulation of miRNA activity are

177 MicroRNAs (miRNAs) and RNA-binding proteins (RBPs) criti

178 MicroRNAs (miRNAs) are a group of small RNAs that contro

179 MicroRNAs (miRNAs) are important post-transcriptional re

180 MicroRNAs (miRNAs) are involved in many biological pathw

181 MicroRNAs (miRNAs) are involved in the regulation of a n

182 MicroRNAs (miRNAs) are key post-transcriptional regulato

183 MicroRNAs (miRNAs) are known to play important roles in

184 Some microRNAs (miRNAs) are known to suppress breast cancer.

185 MicroRNAs (miRNAs) are negative modulators of gene expre

186 Mature microRNAs (miRNAs) are processed from hairpin-containing

187 MicroRNAs (miRNAs) are promising multiple sclerosis (MS)

188 We found that 15 microRNAs (miRNAs) are regulated by progesterone via PR-

189 MicroRNAs (miRNAs) are short, noncoding RNAs involved in

190 MicroRNAs (miRNAs) are small non-coding RNA species that

191 MicroRNAs (miRNAs) are small, non-coding RNAs that play

192 MicroRNAs (miRNAs) are small, noncoding RNAs that modula

193 veral groups have evaluated the potential of microRNAs (miRNAs) as biomarkers for cardiometabolic dis

194 Here, we investigated microRNAs (miRNAs) as biomarkers of AD response using sm

195 The purpose of our study was to identify microRNAs (miRNAs) as early detectable peripheral biomar

196 we investigated the prognostic potential of microRNAs (miRNAs) at the time of diagnosis in MF.

197 We report a new strategy to regulate microRNAs (miRNAs) biogenesis by using bifunctional smal

198 RATIONALE: Aberrant expression of microRNAs (miRNAs) can have a detrimental role in diseas

199 Invertebrate microRNAs (miRNAs) can suppress developmental variabilit

200 MicroRNAs (miRNAs) constitute a class of small noncoding

201 A growing body of evidence indicates that microRNAs (miRNAs) contribute to this tightly controlled

202 performed nine genome-wide screens for human microRNAs (miRNAs) directly regulating cell-cycle protei

203 MicroRNAs (miRNAs) exert powerful effects on immunity th

204 MicroRNAs (miRNAs) have been known to affect various bio

205 MicroRNAs (miRNAs) impinge on the translation and stabil

206 Little is currently known about the role of microRNAs (miRNAs) in KSHV entry.

207 ere, we investigated the involvement of host microRNAs (miRNAs) in maintaining the viability of C. tr

208 he consideration of the broad involvement of microRNAs (miRNAs) in the regulation of molecular networ

209 Currently, microRNAs (miRNAs) involved in host resistance to APEC a

210 This study aimed to identify novel microRNAs (miRNAs) involved in the regulation of decidua

211 MicroRNAs (miRNAs) loss-of-function phenotypes are mainl

212 Recent studies have shown that microRNAs (miRNAs) play a pivotal role in vascular devel

213 neybee, Apis mellifera, studies suggest that microRNAs (miRNAs) play an important role in the molecul

214 Dysregulation of microRNAs (miRNAs) plays an important role in the pathog

215 MicroRNAs (miRNAs) recently have been established as key

216 MicroRNAs (miRNAs) regulate gene expression through inte

217 While microRNAs (miRNAs) regulate the vast majority of protein

218 The discovery of microRNAs (miRNAs) remains an important problem, particu

219 NF-alpha also affected expression of several microRNAs (miRNAs) that have the potential to suppress P

220 To identify microRNAs (miRNAs) that were increased in the quadriceps

221 Argonaute proteins use microRNAs (miRNAs) to identify mRNAs targeted for post-t

222 Circulating PMPs transfer platelet microRNAs (miRNAs) to vascular cells.

223 ncodes 12 pre-microRNAs that yield 25 mature microRNAs (miRNAs), but their roles in KSHV-induced tumo

224 ors, such as transcription factors (TFs) and microRNAs (miRNAs), have varying regulatory targets base

225 Small non-coding RNAs, in particular microRNAs (miRNAs), regulate fine-tuning of gene express

226 ss small noncoding RNAs (sncRNAs), including microRNAs (miRNAs), that may play roles in regulating ly

227 MicroRNAs (miRNAs), the tiny regulatory RNAs, form compl

228 tency that are processed to yield 25 mature microRNAs (miRNAs).

229 function through down-regulation of specific microRNAs (miRNAs).

230 rcode of the cell origin, including specific microRNAs (miRNAs).

231 A number of microRNAs (miRNAs, miRs) have been shown to play a role

232 MicroRNAs (miRs) are key determinants of gene and protei

233 tudy was to characterize the contribution of microRNAs (miRs) delivered by microvesicles to MC activa

234 Oncogenic microRNAs (miRs) have emerged as diagnostic biomarkers a

235 The in vivo function of microRNAs (miRs) in diabetic retinopathy (DR) and age-re

236 studies profiled the expression of mRNAs and microRNAs (miRs) in lung neutrophils in mice during S. p

237 The aim of the study was to explore specific microRNAs (miRs) in rectal cancer that would predict res

238 n human athletes and investigate the role of microRNAs (miRs) in the repression of HCN4.

239 Recent studies suggested serum/plasma microRNAs (miRs) may predict aGVHD onset.

240 ral axon injury, dysregulation of non-coding microRNAs (miRs) occurs in dorsal root ganglia (DRG) sen

241 How microRNAs (miRs) regulate IOP and glaucoma in vivo is la

242 fact, IRE1alpha RNase processes a subset of microRNAs (miRs), including miR-466 and miR-200 families

243 In the analysis, 10,726 microRNA-mRNA interactions were identified to be associa

244 A total of 19 microRNA-mRNA regulatory pairs were identified within th

245 was subsequently inferred for all predicted microRNA-mRNA target pairs expressed during regeneration

246 r visualization of collective effect of 1181 microRNAs-mRNAs pairs and protein-protein interactions w

247 A-1 (miR-1), a member of the muscle-specific microRNA (myomiR) family, is responsible for direct and

248 Using bioinformatics approaches, a novel microRNA named TrkC-miR2 was predicted within the TrkC g

249 covered 207 unknown minor strand (passenger) microRNAs of known microRNA loci and 495 novel putative

250 during cataract formation, and regulation of microRNAs on genes is associated with lens development.

251 We characterize 21 novel microRNAs, one of which may trigger phasiRNAs from numer

252 y roles of the 3'UTRome as binding sites for microRNAs or RNA binding proteins, or during alternative

253 r cortical thinning classifier included nine microRNAs, p=3.63 x 10(-08), R(2)=0.358, permutation-bas

254 Editing in microRNAs, particularly in seed can significantly alter

255 Through a new hypothesis-driven and microRNA-pathway-based SNP (miR-SNP) association study w

256 MicroRNAs play an important role in regulating ER stress

257 The expression of 10 microRNAs predicted to target SFRP1 was also quantified

258 P1 methylation or alter the expression of 10 microRNAs predicted to target SFRP1.

259 t interaction with a large subset of primary microRNAs (pri-miRNAs) in mammalian cells.

260 der, suggesting DROSHA- and DICER1-dependent microRNA processing variability.

261 onal activators, RNA, chromatin remodellers, microRNA-processing proteins and splicing factors.

262 ell exhaustion, epigenetic changes, abnormal microRNA profiles, immunosenescence, and a low-grade chr

263 as attributable to epigenetic alterations at microRNA promoters.

264 reases the plasma abundance of tumor-derived microRNA rapidly after treatment.

265 eraction occurred between miR-18a-5p and the microRNA recognition element of miR-18a-5p in the 3'-unt

266 MicroRNAs regulate gene expression and may play a role i

267 rthermore, several new insights into dynamic microRNA regulation in cancers have been discovered in t

268 These data are the first demonstration of microRNA regulation of DCC and suggest that, by regulati

269 It is proposed that the Cu-microRNA regulatory circuits are further co-opted by pla

270 ection for multiple testing, three of the 78 microRNAs remained significant.

271 tial expression of 18, 12, two, and 17 known microRNAs, respectively.

272 equirement of perfect complementarity of the microRNA seed region to a given target sequence in the m

273 We used 304 high-quality microRNA sequencing (miRNA-seq) datasets from NCBI-SRA a

274 ially expressed, we also identified 57 novel microRNAs, several of which are among the most highly di

275 Ninety microRNAs showed differential expression between familie

276 We sought to describe a microRNA signature of cigarette smoking and relate it to

277 We characterized a novel microRNA signature of cigarette smoking.

278 at tRF biogenesis does not rely on canonical microRNA/siRNA processing machinery (i.e., independent o

279 been a lack of consistent findings among CSF microRNAs studies.

280 on but also viability, showing that a single microRNA target site can be essential.

281 eed region to a given target sequence in the microRNA/target model has proven to be a more efficient

282 ng show increases in several disease-related microRNAs targeting the activin A receptor type 1C (ACVR

283 One potential microRNA that regulates Bcan is miR-9, and overexpressio

284 A390 (miR390) is an evolutionarily conserved microRNA that targets the Trans-Acting Short Interferenc

285 amily comprises a group of broadly conserved microRNAs that are highly expressed in hematopoietic ste

286 Notably, cerebrospinal fluid (CSF) contains microRNAs that may serve as biomarkers for neurological

287 sisting of two RNA-binding proteins and four microRNAs that modulate the mRNA stability landscape of

288 t roles in obesity metabolism and identified microRNAs that significantly negatively correlated with

289 KSHV encodes 12 pre-microRNAs that yield 25 mature microRNAs (miRNAs), but t

290 For experimental verification of this microRNA, the predicted TrkC-premir2 sequence was overex

291 and AGO4) have been thought to assemble with microRNAs to form slicer-independent effector complexes

292 st systematically compared the proteomic and microRNA transcriptome of the slow and fast muscles of C

293 Primary microRNA transcripts (pri-miRs) are cleaved by Microproc

294 tudy, gene-based analyses were performed for microRNAs using data of the largest genome-wide associat

295 ein 2 were shown to be regulated by RBPs and microRNAs, usually resulting in their downregulation.

296 Unlike mRNAs, microRNAs were not asymmetrically distributed.

297 Although several microRNAs were predicted to bind CircPVT1, only let-7 wa

298 Surprisingly, the levels of most microRNAs were stable between the two time points.

299 d, and replicated 3 differentially expressed microRNAs, which were upregulated in patients with IS co

300 NA sequencing revealed 29 Spirodela-specific microRNA, with only two being shared with Elaeis guineen