ライフサイエンスコーパス: microfibrillar

1 Composed of a gecko-inspired elastomeric microfibrillar adhesive membrane supported by a pressure

2 Large collagen VI microfibrillar aggregates were present at the top of the

3 ermis of photoaged forearm skin, with sparse microfibrillar apparatus and interstitial collagen.

4 nd III, collagen VII, and the fibrillin-rich microfibrillar apparatus in this area.

5 ignificant increases in the abundance of the microfibrillar apparatus was observed proximal to the de

6 finding was the association of myocilin with microfibrillar architecture in sheath-derived plaques wh

7 thermore, high-resolution measurement of the microfibrillar architecture of cell walls suggests that

8 imarily from reversible alterations in supra-microfibrillar arrangements rather than from intrinsic e

9 ation is due primarily to the failure by the microfibrillar array of the adventitia to sustain physio

10 t the importance of Ca2+ to microfibrils and microfibrillar arrays in vivo.

11 lyses of isolated Ca2+-containing, staggered microfibrillar arrays were used to interpret the effects

12 n the gross organization and distribution of microfibrillar arrays.

13 to sustain hemodynamic stress by disrupting microfibrillar assembly, by impairing the homeostasis of

14 d exert a strong dominant negative effect on microfibrillar assembly, leading to a loss of normal loc

15 nt fibrillin-1 can participate in productive microfibrillar assembly.

16 rotein, as the primary determinant of failed microfibrillar assembly.

17 r triple-helix formation but is critical for microfibrillar assembly.

18 -2 and suggest that MAGP-2 may help regulate microfibrillar assembly.

19 clude elastic fibre maturation by disrupting microfibrillar assembly.

20 ed a dominant-negative effect on collagen VI microfibrillar assembly.

21 MFAP4 (microfibrillar-associated protein 4) is an extracellular

22 We further show that the proangiogenic microfibrillar-associated protein 5 (MFAP5) is a direct

23 ovarian tumour samples and find that stromal microfibrillar-associated protein 5 (MFAP5) is a prognos

24 alcium-dependent signaling pathway involving microfibrillar-associated protein 5 (MFAP5), focal adhes

25 Microfibrillar-associated protein-1/2 was found with ela

26 elastin-associated proteins fibrillin-1 and microfibrillar-associated protein-1/2 were identified wi

27 antibodies against elastin, fibrillin-1, and microfibrillar-associated protein-1/2.

28 lar weight components of the fibrillin-based microfibrillar complex.

29 at may influence its associations with other microfibrillar components.

30 missense mutation (C1039G) revealed impaired microfibrillar deposition, skeletal deformity, and progr

31 rs a spontaneous internal duplication in the microfibrillar glycoprotein fibrillin-1, might show whet

32 The microfibrillar glycoprotein gene, fibrillin 1 (FBN1), on

33 ng electron microscopy of up to six distinct microfibrillar lamellae.

34 suggesting that Wnts contribute to increased microfibrillar matrices in Tsk skin.

35 se studies highlight that the fibrillin-rich microfibrillar network associated with the upper dermis

36 al non-collagenous regions, forms a distinct microfibrillar network in most connective tissues.

37 icroscopy revealed that the papillary dermal microfibrillar network was truncated and depleted in pho

38 rotein interacts with elastin fibers and the microfibrillar network.

39 ibute to the biomechanical properties of the microfibrillar network.

40 Extracellular microfibrillar networks composed of fibrillins and their

41 ular microenvironments composed of intricate microfibrillar networks influence cell fate decisions in

42 Whether fibrillins form independent microfibrillar networks or can co-polymerize, forming a

43 oteins and their assembly into extracellular microfibrillar networks with focal aggregation of microf

44 To investigate the microfibrillar organization and structural properties of

45 N2 gene, which encodes an elastin-associated microfibrillar protein called fibrillin-2.

46 N1 gene, which encodes the connective-tissue microfibrillar protein fibrillin 1.

47 onnective tissue, caused by mutations of the microfibrillar protein fibrillin-1, that predisposes aff

48 inhibition of sulfation was shown to prevent microfibrillar protein incorporation into the extracellu

49 The related microfibrillar protein MAGP-1 was also found to interact

50 VI is a ubiquitously expressed extracellular microfibrillar protein.

51 n fibrosis via its interface with associated microfibrillar proteins and type I collagen; in particul

52 d decorin secretion, suggesting that the two microfibrillar proteins can associate in the absence of

53 The microfibrillar proteins include, among others, the fibri

54 Little is known about how microfibrillar proteins interact to support fiber assemb

55 ults demonstrate for the first time that the microfibrillar proteins MAGP-1 and MAGP-2 can function o

56 Microfibrillar proteins mainly include fibrillins and mi

57 olecular basis of its interaction with other microfibrillar proteins, deletion constructs of MAGP1 we

58 onstrated that amino-terminal domains of two microfibrillar proteins, fibrillin-1 and fibrillin-2, in

59 Wnt3a markedly stimulated matrix assembly of microfibrillar proteins, including Fbn-1, by cultured fi

60 Six of 13 positive clones encoded known microfibrillar proteins, including fibrillin-1 and -2.

61 acilitating the deposition of elastin onto a microfibrillar scaffold via direct molecular interaction

62 indicated that 1a and 1b self-organize into microfibrillar species, whereas 1c and 1d do not.

63 The effects of microfibrillar stiffening factors k(1) and k(2), the cel

64 om model structures of the axially projected microfibrillar structure and the observed X-ray diffract

65 on, thereby retaining the essentially native microfibrillar structure.

66 membrane where they are integrated into the microfibrillar structure.

67 change in either molecular or macromolecular microfibrillar structure.

68 Muscle-driven actuation of biomimetic microfibrillar structures is achieved using integrative

69 plain the difficulty in isolating individual microfibrillar structures.

70 These morphologically heterogeneous microfibrillar systems are found in many vertebrate tiss