ライフサイエンスコーパス: microfluidic

1 assays and analytical devices based on paper microfluidics.

2 der flow, and this was tested in vitro using microfluidics.

3 e endothelial permeability in vitro based on microfluidics.

4 cant when the microcapsules were produced by microfluidics.

5 -in-time flow, can drive efficient mixing in microfluidics.

6 e-scale analysis, conventionally provided by microfluidics.

7 ss in other fields such as soft robotics and microfluidics.

8 oretic separation systems in capillaries and microfluidics.

9 g and fine control of fluid flow in flexible microfluidics.

10 Using a microfluidic 3D cell migration assay, we found that the

11 this review we focus on 'controlled droplet microfluidics' - a portfolio of techniques that provide

12 nces in miniaturization, nanotechnology, and microfluidics, along with developments in cloud-connecte

13 Microfluidic and CFD circulation models were designed to

14 We apply microfluidic and fluorescent spectroscopy techniques to

15 echium oil and quercetin or sinapic acid by microfluidic and ionic gelation techniques.

16 diagnostic assays implemented in paper-based microfluidic and screen printing devices over the past d

17 Integration of microfluidics and electrical sensing modality in a 3D tu

18 showed suitability for microfabrication, and microfluidic applications requiring precise control of f

19 0%), but Polyjet printing is more suited for microfluidic applications where flow splitting is not re

20 to promote mixing for various electrokinetic microfluidic applications.

21 inting technology most suitable for specific microfluidic applications.

22 rapid, instrument-free and highly sensitive microfluidic approach has great potential for point-of-c

23 We developed a microfluidic approach which allows measurement of shear

24 Using a microfluidic approach, we find that E. coli cells respon

25 Using a microfluidic approach, we find that potassium ion channe

26 Utilizing a microfluidic approach, we found that stable gradients of

27 The developed microfluidic aptasensor has the potential to be used for

28 nce of CTC isolation technologies depends on microfluidic architectures, the underlying principles of

29 Measurement electronics and microfluidics are easily constructed for acoustic wave b

30 ng (SAXS) and high throughput, droplet based microfluidics as a powerful tool to investigate macromol

31 systematically test these hypotheses using a microfluidics assay to mechanically wound an epithelial

32 We developed a platform for microfluidics-assisted cell screening (MACS) that overco

33 with sequence tags that can be read out with microfluidic barcoding and DNA sequencing.

34 Here, we present a high-throughput, microfluidic-based assay for automated manipulation and

35 A fully automated microfluidic-based electrochemical biosensor was designe

36 Moreover, in a microfluidic-based human neuronal model of viral latency

37 Here we present a microfluidic-based mini-metagenomic method which offers

38 e present a new technology that integrates a microfluidic-based nanoparticle synthesis method and For

39 In bone marrow samples, the microfluidic-based plasma cell counts exhibited excellen

40 Here, we describe a microfluidics-based approach enabling direct imaging of

41 have also highlighted different deliverable microfluidics-based approaches and recent prototypes for

42 as Boyden chamber assay, barrier assays, and microfluidics-based assays), in this short report we wil

43 We recently developed a simple but unique microfluidics-based culture approach that requires minim

44 Here, we have used a microfluidics-based platform to investigate the activati

45 Here we describe a microfluidics-based strategy to spin liquid native silk,

46 Compared with the paper-free non-hybrid microfluidic biochip over a period of three months, the

47 ip over a period of three months, the hybrid microfluidic biochip was found to have a much longer she

48 We developed microfluidic bioreactors to enable the investigation of

49 r high-throughput fabrication of paper-based microfluidics by patterning hydrophobic barriers using a

50 ork reports a high throughput and label-free microfluidic cell deformability sensor for quantitative

51 as small as 50 muL is made possible using a microfluidic cell.

52 electrode in an electrochemical miniaturized microfluidic cell.

53 , with an integrated and low-cost disposable microfluidic chamber for handling of biological samples,

54 iniaturized SAF microlens array as part of a microfluidic chamber in thermoplastic material and perfo

55 sing as a function of flow rate ratio of the microfluidic chamber inlets.

56 orate three independent inlet channels and a microfluidic chamber with an monolithically integrated t

57 orous anolyte chamber is formed by filling a microfluidic chamber with three-dimensional graphene foa

58 under shear stress in an ex vivo shear flow microfluidic chamber.

59 ytes was validated in a dorsal root ganglion microfluidics chamber platform.

60 Using microfluidic chambers to separate and injure distal axon

61 ding a PDMS flow cell with a 50microm height microfluidic channel fabricated with double-sided adhesi

62 A polydimethylsiloxane (PDMS) microfluidic channel is used to efficiently and reproduc

63 press streaming potential using an Ag-coated microfluidic channel on a p-type silicon nanowire (SiNW)

64 ated with low-dose TNFalpha (0.3 ng/ml) in a microfluidic channel that produced a linear SS gradient

65 a Fabry-Perot type acoustic resonator into a microfluidic channel to separate submicrometer particles

66 in which an electric field is coupled into a microfluidic channel using shear-horizontal surface acou

67 TO) three-electrode sensor integrated with a microfluidic channel was designed for label-free immunos

68 ion, we model the cell dynamic behavior in a microfluidic channel with constriction and quantify the

69 n-chip planar Goubau line, integrated with a microfluidic channel, which is capable of low-loss, tera

70 ensors (50microm diameter) incorporated in a microfluidic channel.

71 Our LOAD customized design of microfluidic channels allows automation to mimic sequent

72 o accomplish this, we constructed perfusable microfluidic channels by embedding sacrificial circular

73 Microfluidic channels were filled with buffers containin

74 f scaffolds for cell culture, reconfigurable microfluidic channels, and microswimmers.

75 nd downstream extensions and integrated into microfluidic channels.

76 s within straight, rectangular cross section microfluidic channels.

77 usly been used to measure fluid flow rate in microfluidic channels.

78 Three recently reported microfluidic chemiluminescence (MF-CL) methods (based on

79 This is critical for the development of microfluidic chemosensitivity and resistance assay (CSRA

80 Here, we use bioengineered 'microfluidic chest cavities' to precisely control the me

81 ounts (10(4) cfu/mL) using a custom-designed microfluidic chip and monitor their individual growth ra

82 l enzymatic digestion methods with a polymer microfluidic chip based enzyme reactor.

83 The microfluidic chip contained packed silica microbeads zon

84 at interfaces the phone with a silicon-based microfluidic chip embedded within a credit-card-sized ca

85 is study reports an all-polydimethylsiloxane microfluidic chip integrated with screen-printed carbon

86 The 3D microfluidic chip reduces reactant consumption and facil

87 coccus strain was performed on the developed microfluidic chip within 30min, and the limit of detecti

88 A disposable microfluidic chip, prefilled with biomarker-specific rea

89 Algae are grown in glass based microfluidic chip, which contains integrated optical pH

90 d on a glass substrate and integrated with a microfluidic chip.

91 covery, and post-recovery imaging all on one microfluidic chip.

92 hous silicon (a-Si:H) photosensors below the microfluidic chip.

93 arily immobilizing suspension cells within a microfluidics chip.

94 In this work, we present the combination of microfluidic chips and mass spectrometry employing laser

95 r, the handling of magnetic particles inside microfluidic chips for miniaturized assays is often chal

96 ction, enumeration and characterization with microfluidic chips has critical significance in cancer p

97 cant advantages compared to the conventional microfluidic chips including cost-effectiveness, ease of

98 nce microscopy combined with high-throughput microfluidic chips is a powerful method to obtain inform

99 nder different environments, high-throughput microfluidic chips require complex preparatory work.

100 By keeping the electronics separate from microfluidic chips, the former can be reused and device

101 esign, fabrication and testing of 3D printed microfluidics chips coupled with silicon photomultiplier

102 Using microfluidics combined with fluorescence microscopy, we

103 on the K-channel as a versatile, easy to use microfluidic component enabling diverse, in-droplet (bio

104 ypes of NMR chips aiming for straightforward microfluidic connectivity.

105 ilitate such developments, we have adapted a microfluidic constriction sorter device to separate a wi

106 ring-mixer device and a 32-channel tabletop microfluidic controller.

107 surface, i.e., "in-chip" microstructures for microfluidic cooling of chips, vias, MEMS, photovoltaic

108 We recently described a high-throughput microfluidic CTC-iChip, which efficiently depletes hemat

109 -dimensional GC (GC x GC), prior to multiple microfluidic (Deans) switching for selection of componen

110 at 0.1% parasitemia as a testing sample, the microfluidic deformability sensor achieved an excellent

111 gy to the microscopy and flow cytometry, the microfluidic deformability sensor would possibly allow f

112 In an open microfluidic device adapted for single-cell electrophore

113 the help of arrays of insulating posts in a microfluidic device around which electric field gradient

114 Consequently, the microfluidic device described here provides fast and com

115 We present a microfluidic device designed to monitor the endothelium

116 The microfluidic device enabled quantitative time-lapse micr

117 ave developed a simple capillary force-based microfluidic device for 2D and 3D cell co-cultures.

118 ide detection platforms, there is no compact microfluidic device for the complementary, fast, cheap,

119 The microfluidic device is based on a herringbone channel de

120 In this work, a microfluidic device is developed for in-situ analysis of

121 e studied autochemotaxis quantitatively in a microfluidic device of bifurcating channels: Branch choi

122 cose oxidase (GOx) with an electroanalytical microfluidic device of easy assembly based on cotton thr

123 reliability, and portability, the developed microfluidic device provides a simple method for antimic

124 -based cell assay carried out in a segmental microfluidic device that allows studying the effect of a

125 In this work, we have developed a microfluidic device that is able to simultaneously chara

126 we developed an integrated double-filtration microfluidic device that isolated and enriched EVs with

127 We describe a microfluidic device that isolates and enumerates periphe

128 Using a "Crystal Hotel" microfluidic device to provide well-defined, nanoliter v

129 use an HPLC coupled to a droplet generating microfluidic device to sequentially encapsulate the elut

130 We anticipate this microfluidic device will facilitate drug screening in a

131 pesticides with algae in a novel glass based microfluidic device with integrated optical pH, oxygen s

132 crofluidics was conducted using a Y-junction microfluidic device, the design of which was optimized f

133 Finally, using a microfluidic device, we found that the effects of ACM we

134 igital LAMP to be performed in a self-driven microfluidic device.

135 nd subjected to chemokine gradients within a microfluidic device.

136 of microwells (7 pL each) in a multilayered microfluidic device.

137 e trapped on-demand in the downstream of the microfluidic device.

138 n spreading of tau in a unique three-chamber microfluidic device.

139 ed by nanoprecipitation in a glass capillary microfluidics device.

140 Microfluidic devices >500 mum, rapid mixing (71% +/- 12%

141 per determine the performance of paper-based microfluidic devices and permit the design of cellular a

142 Single-cell microfluidic devices are poised to substantially impact

143 We investigated drug absorption into microfluidic devices by treating multiple myeloma (MM) t

144 Microfluidic devices constructed using low cost material

145 e a potential application of the paper-based microfluidic devices fabricated by the proposed method,

146 Currently, reliable valving on integrated microfluidic devices fabricated from rigid materials is

147 aking it ideal for integration with existing microfluidic devices for advanced cell and pharmacokinet

148 Microfluidic devices have the potential to automate and

149 In order to engineer in-droplet assays, microfluidic devices must add reagents into droplets, re

150 ectrophoretic (DEP) mechanisms integrated in microfluidic devices offer unique advantages for such ap

151 Herein we explored the use of microfluidic devices or microchambers as simple and low-

152 may be carried out on a continuous basis in microfluidic devices or split-flow thin channel (SPLITT)

153 -delivery microparticles, pH sensors, and 3D microfluidic devices that we could not produce using tra

154 low-cost fabrication of electrochemical LOC microfluidic devices to be used for enzymatic detection.

155 cal vein endothelial cells (HUVECs) grown in microfluidic devices were treated with Angiopoietin 1 an

156 have a wide range of applications including microfluidic devices with customizable wettability, sola

157 entially new approach for the manufacture of microfluidic devices with multiple integrated functional

158 is a commonly used elastomer for fabricating microfluidic devices, but it has previously been shown t

159 ormance of and monitoring experiments within microfluidic devices, but this application suffers from

160 alytes have been developed using paper-based microfluidic devices, the detection and analysis of bloo

161 ing effects are expected to be acute in open microfluidic devices, where a single, high-conductivity

162 for the operation of macroscale machines and microfluidic devices.

163 ation of isothermal amplification methods in microfluidic devices.

164 holding geometries, specifically paper-based microfluidic devices.

165 sympathetic and sensory neurons cultured in microfluidic devices.

166 olutionary technology for the fabrication of microfluidic devices.

167 formation at relatively warm temperatures in microfluidic devices.

168 and promoted neurite growth and branching in microfluidic devices.

169 Paper-based microfluidic diagnostics first emerged in 2007 as a low-

170 view, we examine the advances in paper-based microfluidic diagnostics for medical diagnosis in the co

171 ylsiloxane (PDMS) wristband with an embedded microfluidic diaphragm pressure sensor capable of real-t

172 The proof of concept of utilizing a microfluidic dielectrophoresis (DEP) chip was conducted

173 ic systems can be positioned between digital microfluidics (DMF) addressing each droplet individually

174 iques are used to improve the sensitivity of microfluidic DNA analysis platforms.

175 Here we describe a microfluidic DNA preconcentration technique that does no

176 encapsulation in droplets of a monodisperse microfluidic double water-in-oil-in-water emulsion (MDE)

177 We introduce a microfluidic double-jump mixing device for investigating

178 extract after being separated in HPLC using microfluidic droplets online and represents an advance i

179 clusters of tumor cells compartmentalized in microfluidic drops reveal that cells within a cluster ha

180 A novel fully disposable microfluidic electrochemical array device (microFED) was

181 Here, we present a simultaneous microfluidic electrochemical biosensing system to detect

182 On the basis of the developed microfluidic electrochemical sensor system, we successfu

183 address these challenges, here we integrate microfluidics, electronics, and inkjet printing to build

184 diffusive losses of protein out of the open microfluidic electrophoretic (EP) cytometry device.

185 Here, we disclose an integrated microfluidic emulsion creamer that packs ("creams") assa

186 ies but also allows for repeated wounding in microfluidic environments.

187 In this study, a paper-based microfluidic enzyme-linked immunosorbent assay (ELISA) w

188 ace velocity and geometrical factors through microfluidic experiments that mimic some of the confinem

189 Here, we use microfluidic experiments, mechanistic models, and game t

190 Here, by combining liquid crystal microfluidic experiments, nonequilibrium molecular dynam

191 customized immunoassay platform following a microfluidic filter device to detect and quantify anti-H

192 -response, pressure-driving pumps allows the microfluidic flow to be quickly and accurately changed,

193 The graphene foam enabled microfluidic flow-through approach will allow efficient

194 on a miniaturized microbial fuel cell with a microfluidic flow-through configuration: a porous anolyt

195 electrodes and ultrahigh throughput droplet microfluidics focused on the generation of hundreds of t

196 ng a low thermal mass micro thermostat and a microfluidic glass chip as central elements were designe

197 velopment of a compact paper-based enzymatic microfluidic glucose/O2 fuel cell that can operate using

198 control oxygen gradients, eliminates complex microfluidic handling, allows for incorporation of addit

199 Microfluidics has been extensively used for this purpose

200 hanced speed, accuracy, and cost-efficiency, microfluidics has demonstrated potential in several key

201 Microfluidics has great potential, but the complexity of

202 The field of microfluidics holds great promise for the development of

203 ditions, and increasing sRBC adhesion in our microfluidic human microvasculature models.

204 ge numbers of concurrent separations is open microfluidics (i.e., no microchannels).

205 iation switch, we employed a high-throughput microfluidic imaging system that allows real-time and si

206 esents a novel poly(dimethylsiloxane) (PDMS) microfluidic immunosensor that integrates a complementar

207 We report the use of Microfluidic Impedance Cytometry (MIC) to characterise t

208 rating for the first time the feasibility of microfluidics in this field.

209 inhibited many biologists from pursuing new microfluidic innovations.

210 Droplet microfluidics is a relatively new and rapidly evolving f

211 Droplet microfluidics is among the most promising candidates for

212 these directions, which demonstrate that 2D microfluidics is uniquely set to study complex out-of-eq

213 e current status of PDT investigations using microfluidic Lab-on-a-Chip systems, including recent dev

214 and pathologic jaundice but adapts it to the microfluidic level for the ultimate purpose of total bil

215 versatile device is an optimal platform for microfluidic magnetic resonance in particular, but equal

216 gradients can guide these swimmers through a microfluidic maze.

217 Here the authors develop a microfluidic method to identify and quantify low-abundan

218 We use a microfluidic method to produce uniform concentrated susp

219 The microfluidics method enabled tracking of the effect of t

220 In this study, we present a microwave-based microfluidic mixer that allows rapid mixing within indiv

221 ign insights for developing low-cost surface microfluidic mixing devices on open substrates.

222 Here, we use a synthetic microfluidic model of a passive loader to explore the no

223 This microfluidic model of vascular-tissue interface can be u

224 ical properties by leveraging novel in vitro microfluidic models of the microcirculation, including 1

225 We designed a microfluidic module that generates complex and dynamic c

226 ermally coupled with another glass hosting a microfluidic network made in polydimethylsiloxane that i

227 siloxane (PDMS) for the rapid fabrication of microfluidic networks and the utility of polyacrylamide

228 reaction vessels which can be manipulated in microfluidic networks, and has seen a rapid growth in de

229 s on areas where key fundamental features of microfluidics open up new possibilities and present adva

230 "paper" substrates for lateral flow assays, microfluidic paper analytical devices and other point-of

231 This article describes a 3D microfluidic paper-based analytical device that can be u

232 Three-dimensional microfluidic paper-based analytical devices (3D-muPADs)

233 ation sites were mapped using a high-density microfluidic peptide array and confirmed by ectopic expr

234 total of 34 blood samples were analyzed with microfluidic photo treatment-image analysis (muPIA) and

235 In this paper, we use a high-throughput microfluidic platform as a quantitative screen to assess

236 nation of single-cell microscopy and a novel microfluidic platform capable of screening thousands of

237 dvantageously, sensitivity of the diagnostic microfluidic platform devised for oxytocin determination

238 We developed a droplet microfluidic platform for the screening and separation o

239 Therefore, we hereby report a microfluidic platform lab-on-a-disc (LOAD) to provide a

240 re-shell MIP sensor particles into a modular microfluidic platform that allows for an in-line phase-t

241 Here, we report a 3D microfluidic platform that could be potentially used for

242 This work demonstrates a droplet microfluidic platform that has the potential to signific

243 tation to our existing protocol describing a microfluidic platform that offers additional application

244 We present an integrated microfluidic platform to analyze a large number of singl

245 molecular weight DNA, using the 10x Genomics microfluidic platform to partition the genome.

246 We describe a new microfluidic platform to perform immunochromatographic a

247 For this purpose, a robust and low cost microfluidic platform was fabricated for achieving the m

248 Here we report the development of a flexible microfluidic platform with fully integrated sensing for

249 This technique involves a custom-made glass microfluidic platform, in which oil droplets can be trap

250 plying environmental stress to bacteria in a microfluidic platform, we can correctly assign antibioti

251 Using a state-of-the-art microfluidic platform, we measure noise dynamics in agin

252 neurogenesis and angiogenesis models using a microfluidic platform, which is a critical step toward t

253 nd temperature was achieved using a flexible microfluidic platform.

254 e dynamics in single, dual and multiple unit microfluidic platforms (Solo-MFP, Duet-MFP and Quintet-M

255 The ceramic microfluidic platforms incorporate three independent inl

256 ibody recognition, has been miniaturized for microfluidic platforms to reduce reagent and sample cons

257 Quantitative microfluidic point-of-care testing has been translated i

258 A microfluidic processor is used to separate the Watson an

259 erwise poor accessibility and scalability of microfluidic prototyping.

260 We developed a microfluidic reactor that physically separates Geobacter

261 the characteristic physical features of the microfluidic regime, the integration of microfluidics wi

262 igns and fabrication instructions for both a microfluidic ring-mixer device and a 32-channel tabletop

263 The microfluidic route to vesosomes offers an exceptional pl

264 pands the generality of ultrahigh-throughput microfluidic screening.

265 oducible, chip scale, ultra-high sensitivity microfluidic sensor arrays.

266 Improving microfluidic size-based particle/cell sorting is a chall

267 Our sensing platform comprises a microfluidic spray nozzle and a microcantilever array op

268 Tissue microarray and microfluidics staining methods have emerged as powerful

269 Here we report on a multistep microfluidic strategy for hierarchically assembling unif

270 e possibility of dual-channel operation of a microfluidic stripline NMR setup showing one- and two-di

271 ility of primitive erythroblasts, assayed by microfluidic studies and fluorescence imaged microdeform

272 Here we show that a microfluidic system supports murine ovarian follicles to

273 a novel and easily operated high-throughput microfluidic system to observe 96 different GFP-tagged y

274 Here, a microfluidic system with computer controlled compound pe

275 Studies in a three-dimensional microfluidics system identified a pericyte-dependent rol

276 onality and complexity of controlled droplet microfluidic systems can be positioned between digital m

277 ificant progress has been made in developing microfluidic systems for nucleic acid and whole bacteria

278 otocol to manufacture disposable, 3D-printed microfluidic systems for sample preparation of petroleum

279 Droplet-based microfluidic systems that incorporate flowing streams of

280 nd high throughput capacity of droplet-based microfluidic systems.

281 vivo analysis of the pathway activity with a microfluidic taxis assay and mathematical modeling to in

282 We report a label-free microfluidic technique to separate live and dead cells t

283 resistance to dissolution evaluated using a microfluidic technique.

284 on and poor longevity of gradients utilizing microfluidic techniques.

285 We present a critical review of microfluidic technologies and material effects on the an

286 an in situ chemotaxis assay (ISCA) based on microfluidic technology.

287 Using electronically programmable microfluidics, the measurement is in turn used to contro

288 assisted purification of nuclei with droplet microfluidics to develop a highly scalable single-nucleu

289 Here, we used live-cell imaging and microfluidics to investigate the adaptive response of bu

290 mic sequencing (SiC-seq), which uses droplet microfluidics to isolate, fragment, and barcode the geno

291 and continuous technique utilizing inertial microfluidics to separate E. gracilis by a key shape par

292 oncentration method can be integrated into a microfluidic total analysis system composed of in-line D

293 ceptual foundation for developing autonomous microfluidic transport devices driven by bacterial fluid

294 In this study, we developed a biomimetic microfluidic tumor microenvironment (bMTM) comprising co

295 igh-performance assay chemistry performed at microfluidic volumes on Au pads directly at the PCB surf

296 he three 3D printing technologies dominating microfluidics was conducted using a Y-junction microflui

297 of hydrogels and successful integration with microfluidics, we developed a class of hydrogels that co

298 Here, using nematic microfluidics, we study the cross-talk of topological de

299 the microfluidic regime, the integration of microfluidics with orthogonal systems and the generation

300 Using microfluidics with single-molecule imaging, we simultane