ライフサイエンスコーパス: microsome

1 e same pattern ex vivo (COS-1) and in vitro (microsomes).

2 lysates (e.g., human T47D breast cancer cell microsomes).

3 PZQ)Cr(CO)3 (1 and 2), by use of human liver microsomes.

4 inhibit isomerohydrolase activity in the RPE microsomes.

5 t this compound is stable in serum and liver microsomes.

6 (S)-mephenytoin hydroxylation in human liver microsomes.

7 PDH type 2 and good stability in mouse liver microsomes.

8 d biotransformation assay based on rat liver microsomes.

9 lic stability in the presence of human liver microsomes.

10 degrees C and 33 degrees C using control rat microsomes.

11 rohydrolase activity was assessed in the RPE microsomes.

12 hepsin S activity and very poor stability to microsomes.

13 or caffeine-induced Ca(2)(+) release from SR microsomes.

14 on of RyR1-mediated Ca(2)(+) release from SR microsomes.

15 ed RyR-mediated Ca(2)+ leak from skeletal SR microsomes.

16 nd co-fractionates with EGFR in high density microsomes.

17 nd retinal G protein-coupled receptor in RPE microsomes.

18 reactivated upon addition of BAK-containing microsomes.

19 bolism observed in phospholipid-depleted RPE microsomes.

20 etabolism assays performed using human liver microsomes.

21 ith MAM-derived DRMs but not with those from microsomes.

22 ivatives significantly in pooled human liver microsomes.

23 re identified by incubation with human liver microsomes.

24 n native cardiac sarcoplasmic reticulum (SR) microsomes.

25 tionated predominantly with mitochondria and microsomes.

26 oxypalmitate, using CYP77A6-expressing yeast microsomes.

27 ely potent under hypoxia and stable to liver microsomes.

28 which is about 5 times more than that in the microsomes.

29 ence of UDP-Xyl was also identified in these microsomes.

30 ng G6P and increasing P(i) concentrations in microsomes.

31 slation and translocation system with canine microsomes.

32 complete absence of UGT1A proteins in liver microsomes.

33 ated myoblasts, myotubes, or skeletal muscle microsomes.

34 e more metabolically stable in human hepatic microsomes.

35 insect cells and was isolated as insect cell microsomes.

36 th selected lumenal factors inside mammalian microsomes.

37 was detected in dog, human, and monkey liver microsomes.

38 er microsomes than in human and monkey liver microsomes.

39 e majority of this activity co-purified with microsomes.

40 or, [3H]MAEA, bound specifically to the FAAH microsomes.

41 etitively displaced the [3H]MAEA on the FAAH microsomes.

42 long-term PrP-res production than suspended microsomes.

43 ibition is the same for purified protein and microsomes.

44 tion activity of human, mouse, and rat liver microsomes.

45 ydrolase activity from solubilized rat liver microsomes.

46 Derlin proteins to the membrane fraction of microsomes.

47 tion activity of mouse, rat, and human liver microsomes.

48 ly improved metabolic stability to rat liver microsomes.

49 reased RyR1-mediated Ca(2+) release from SkM microsomes.

50 tivity, and its metabolic stability in mouse microsomes.

51 ibition of cytochrome P450s from human liver microsomes.

52 urafenib in in vitro assays with human liver microsomes.

53 itro metabolic turnover of fenclozic acid in microsomes.

54 incubations with HLMs and monkey and rabbit microsomes.

55 native tetramer band in insect cell derived microsomes.

56 ate proteins during their translocation into microsomes.

57 lypeptide lengths, in mammalian cells and ER microsomes.

58 ate stability (t1/2 = 44 min) in mouse liver microsomes.

59 -fold increases in half-lives in mouse liver microsomes.

60 in vitro metabolic stability in human liver microsomes.

61 er metabolic stability than 5 in human liver microsomes.

62 In rat liver microsomes, 2-(3-mercaptopropyl)pentanedioic acid (2-MPP

63 In human liver microsomes, 4-oxo-atRA formation was supported by NAD(+)

64 inhibits lysosome cathepsins and APC-derived microsome activity in vitro and partially inhibits lysos

65 tabolic stabilities in mouse and human liver microsomes, along with acceptable cytotoxicity profiles.

66 lation and good metabolic stability in liver microsome and hepatocyte assays.

67 ng from 20.1 (+/-2.8)% to 71.3 (+/-19.5)% in microsomes and 24.0 (+/-1.5)% to 82.5 (+/-14.0)% in bloo

68 inidine, two prototypic substrates, in liver microsomes and a reconstituted enzyme system with K(i) a

69 OC14 exhibited high stability in mouse liver microsomes and blood plasma, low intrinsic microsome cle

70 nd FTUCAs with proteins present in rat liver microsomes and bovine blood plasma.

71 nstrated by two-phase fractionation of plant microsomes and by in vivo detection of AtCPK5-GFP fusion

72 The results obtained with sealed microsomes and CHO cells indicate that Dol-P, formed fro

73 I metabolic stability studies in mouse liver microsomes and compared to cocaine in locomotor activity

74 oncentration, and stoichiometry in rat liver microsomes and cultured cells.

75 ssment of metabolic stability in human liver microsomes and cytochrome P450 inhibition potential.

76 metabolites was not observed in medaka liver microsomes and cytochrome P450 was not induced with AP/A

77 otein UV photocross-linking studies in rough microsomes and demonstrate that numerous ER integral mem

78 s compound was metabolically stable in liver microsomes and displayed anti-tumor activity in xenograf

79 pids, activity of HMG-CoA reductase in liver microsomes and EPA+DHA incorporation in liver, heart and

80 hadone into its main metabolite by rat liver microsomes and for demonstrating the potential of known

81 HP for deiodinase inhibition using rat liver microsomes and for peroxisome proliferator-activated rec

82 liver microsomes, metabolism by human liver microsomes and hepatocytes, and in vivo disposition in r

83 oligomers was investigated using human liver microsomes and human liver cytosol.

84 able to profile active enzymes in rat liver microsomes and identify pyrethroid-metabolizing enzymes

85 udies were investigated in rat and dog liver microsomes and in the filamentous fungus Cunninghamella

86 abolic stability of 6a and 6m in mouse liver microsomes and in vivo pharmacokinetic profiles in plasm

87 selective PCB biotransformation by rat liver microsomes and in vivo.

88 and favorable metabolism in human intestinal microsomes and liver microsomes make phosphoramidate 16

89 tion of dihydrotestosterone with human liver microsomes and NADPH yielded the 18- and 19-hydroxy prod

90 small degree of re-localization to the light microsomes and nucleus in response to insulin.

91 Metabolite formation in microsomes and plasma could be completely inhibited with

92 lead revealed short metabolic half-lives in microsomes and rapid clearance in the rat.

93 detanib) were characterized by using hepatic microsomes and recombinant proteins.

94 lity when incubated with rat and human liver microsomes and showed no significant cytochrome P450 (CY

95 with low predicted metabolism in human liver microsomes and which showed prolonged exposure in mice.

96 n vitro (kinase assay), ex vivo (human liver microsomes) and in vivo (mouse) model systems.

97 osomal in vitro assay (Wistar-Han rats liver microsomes), and with concomitant formation of PFCAs, PF

98 hows high metabolic stability in human liver microsomes, and displays excellent selectivity in a scre

99 erum, low rates of metabolism in human liver microsomes, and high oral bioavailability in animal mode

100 are stable in simulated gastric fluid, liver microsomes, and human blood and are largely free from bi

101 lture, enhanced metabolic stability in liver microsomes, and improved tolerability in mice.

102 amide into ceramide in vitro using rat liver microsomes, and the formation of tritiated water after t

103 ediment fractions were incubated with S9 rat microsomes, and the metabolites were extracted with a ne

104 mic reticulum membrane," "cytochrome P450," "microsome," and "oxidation reduction") and moderate CP (

105 uctural 3/4A (NS3/4A) protease from replicon microsomes are potently inhibited by BV.

106 In human placental microsomes, aromatase activity was inhibited with IC(50)

107 trifluoperazine penetrates well into the SR microsome as expected from the reported and calculated l

108 bicistronic human-cyt P450 3A4 (bicis.-3A4) microsomes as enzyme sources.

109 This effect occurred for CFTR channels in microsomes as well as in intact cells and at the same co

110 ing/leak from cardiac and skeletal muscle SR microsomes as well as the function of RyRs in planar bil

111 to cytochrome P450 metabolism using a liver microsome assay.

112 Using cell-based and cell-free microsome assays, we found that the truncated protein la

113 ter than 10 KDa in crude cytosol that affect microsome-associated glucose-6-phosphatase activity.

114 her reaction of organic nitrite with free or microsome-associated thiols led to NO or nitrosothiol ge

115 degrees C and 30 degrees C using control rat microsomes at varying concentrations of chlorzoxazone.

116 ions and alanine substitutions) and in vitro microsome-binding assays with the SUS1 protein to define

117 Mouse liver microsome bioconversion of the methamidoxime prodrugs is

118 s)/cytosol increased 2.7-fold, especially in microsomes but not mitochondria.

119 creased ROS parameters in the isolated liver microsomes, but isoniazid treatment did not.

120 Ret-NH2 binds a protein(s) in the RPE microsomes, but it does not bind RPE65, a protein implic

121 tivity of glucose-6-phosphatase in wild-type microsomes by decreasing K(m).

122 COPII vesicles are separated from the microsomes by differential centrifugation.

123 Moreover, CerS activity in BAK KO microsomes can be reactivated upon addition of BAK-conta

124 r microsomes and blood plasma, low intrinsic microsome clearance, and low plasma-protein binding.

125 crodialysis infusion of M+4 cortisone to the microsomes coincubated with a proprietary 11beta-HSD1 in

126 ly improved the metabolic stability in liver microsomes compared to SMART.

127 18)F-FTC-146 has a longer half-life in human microsomes, compared with rodents.

128 n of [(14)C]TAG was only possible with yeast microsomes containing both LPCAT1 and DGAT1-1.

129 Yeast microsomes containing CPTL2/CPT3 showed enhanced synthes

130 zyme is comparable to that observed in liver microsomes, CYP3A4 behaves similarly to that observed in

131 ve intermolecular experiments with rat liver microsomes {(D)V = 12.5; (D)(V/K) = 10.9} but was with p

132 dipocyte cells, TBMEHP inhibited rat hepatic microsome deiodinase activity and was an agonist for PPA

133 In human liver microsomes, difluoro analogue 5b underwent 10,11-epoxida

134 Irradiation of homogenates and microsomes diminished prion infectivity by a factor of a

135 lines, BGLC3 activity was concentrated in a microsome-enriched fraction but also was present in solu

136 Yeast microsomes expressing EaDAcT possessed acetyl-CoA diacyl

137 cted in dephosphorylation) using insect cell microsomes expressing SERCA2a with or without PLN (wild-

138 accumulate within endoplasmic reticulum (ER)/microsome forms toxic oligomers in mouse and human brain

139 ling of the chimeric proteins in low density microsome fractions isolated from stably transfected 293

140 ed by addition of liver mitochondrial and/or microsome fractions.

141 hat lack endogenous ceramidase activity, and microsomes from ACER2-expressiong yeast cells were used

142 l (5-136) was the major metabolite formed by microsomes from all other species.

143 ittle or no glucuronidation was observed for microsomes from cells overexpressing the UGT2B10*2 varia

144 e activity of glucose-6-phosphatase in crude microsomes from cells with high, normal, or low CF activ

145 n for CYP3A4) was reduced by >50% in hepatic microsomes from CYP3A4-HBN mice compared with controls.

146 information about 11beta-HSD1 activities in microsomes from different mammalian species.

147 otope-labeled cortisone to cortisol in liver microsomes from dog, monkey, and human.

148 OR was obtained with freshly prepared intact microsomes from insect cells expressing HPC4-tagged full

149 ooled human liver microsomes (HLMs) or liver microsomes from male guinea pig, hamster, monkey, mouse,

150 l-3'-ol (OH-PCB 102), respectively, by liver microsomes from male rats pretreated with different indu

151 Liver and enterocyte microsomes from MTP-deficient animals synthesize lesser

152 The recombinant OLE3 microsomes from Saccharomyces cerevisiae have been shown

153 ster ovary cells lacking ACAT1, and prepared microsomes from transfected cells.

154 Isolated liver microsomes from untreated rabbits were treated with 1% B

155 When sealed microsomes from wild type cells and cells depleted of Rf

156 The KM of microsomes from wild-type (WT) UGT2B10-overexpressing ce

157 cal states (i.e., membrane bound as in brain microsomes from wild-type mice or purified GPI-anchorles

158 Finally, human liver microsomes genotyped for rs2108622 demonstrated reduced

159 Using isolated intact liver or fat microsomes, glucose-6 phosphate stimulated 11 beta-HSD1

160 long half-life in both human and mouse liver microsomes, good permeability, modest protein binding, a

161 demonstrated the functional activity of the microsomes harboring KcsA showing single-channel current

162 was similar to that observed for human liver microsomes (HLM) against both substrates.

163 abromodiphenyl ether (BDE-47) by human liver microsomes (HLM) and recombinant human CYPs, and to iden

164 The role of CYP was assessed in human liver microsomes (HLM) and tyrosol-to-hydroxytyrosol conversio

165 hylphenol, and 3-methylindole in human liver microsomes (HLM) were analyzed by HPLC coupled with Orbi

166 SAHA glucuronidation phenotype, human liver microsomes (HLM) were analyzed for glucuronidation activ

167 to in vitro biotransformation by human liver microsomes (HLM).

168 s carbon electrode materials and human liver microsomes (HLM).

169 n limits (<1 pmol/mg protein) in human liver microsome (HLMs).

170 ort half-life in the presence of human liver microsomes (HLMs) (T1/2 = 2.91 min).

171 te (AM) from 2-oxoclopidogrel by human liver microsomes (HLMs) is greatly affected by the thiol reduc

172 entative chiral PCB, with pooled human liver microsomes (HLMs) or liver microsomes from male guinea p

173 netic studies, CYP2B6 and pooled human liver microsomes (HLMs) were incubated with BDE-47 (0-60 micro

174 f metabolic enzymes from human and rat liver microsomes, human and rat liver cytosol, and mouse liver

175 iac and skeletal sarcoplasmic reticulum (SR) microsomes (IC values of 6.6 and 9.9 muM, respectively).

176 hoproteomic analysis of canine pancreatic ER microsomes identified 49 high scoring phosphotyrosine-co

177 In vitro metabolism studies in human liver microsomes identified the production of not only the act

178 Glucose-6-phosphatase is associated with microsomes in both Dictyostelium and mammals.

179 ase activity of the mutants was tested using microsomes in HeLa cells and in vitro.

180 olves incubation of cold compound with liver microsomes in the presence of [14C]potassium cyanide.

181 the metabolism of clopidogrel to human liver microsomes in the presence of four reductants, namely, G

182 old to increase half-life in the presence of microsomes in vitro led to identification of compounds w

183 mbrane association in E. coli and with plant microsomes in vitro without reducing enzymatic activity.

184 In rat liver microsomes in vitro, defluorination of 18F-FCWAY was alm

185 oxycotinine (3HC)-glucuronide in human liver microsomes in vitro.

186 and (2) binding to carbonate-stripped plant microsomes in vitro.

187 bit defluorination of 18F-FCWAY in rat liver microsomes in vitro.

188 The stability of 2 was evaluated in microsomes, in plasma, and toward glutathione.

189 mRNA for these four enzymes, and neutrophil microsomes incorporate arachidonoyl chains into phosphat

190 ndent ATPase activity, which was measured in microsomes incubated with 200, 2, and 0.25 microM Ca(2+)

191 d beta-adduction was observed in mouse liver microsomes incubated with styrene at various concentrati

192 e the percent binding results from the FTUAL microsome incubation experiments, 8:2 FTOH was incubated

193 hydroxylation were observed using CYP2D6-HBN microsomes, indicating a significant role for Cyb5 in th

194 for quantity of input PrP-res, scrapie brain microsomes induced dramatically enhanced persistent PrP-

195 zation during the infection process, scrapie microsomes induced less long-term PrP-res production tha

196 of cultured endothelial cells and placental microsomes is actually TFPIbeta based on (1) migration o

197 s discrepancy with the earlier studies using microsomes is probably due to the known accessibility of

198 gn biologically active interfaces with liver microsomes is suggested to have immense significance in

199 face of endothelial cells and from placental microsomes is TFPIbeta.

200 Transport experiments using microsomes isolated from ABCC1-expressing yeast cells sh

201 In experiments with microsomes isolated from COS-1 cells or HepG2 hepatocyte

202 Maximum catalytic function is retained in microsomes isolated from High-Five cells and labeled wit

203 Activity assays with microsomes isolated from tobacco plants transiently expr

204 In isolated cardiac and SkM SR microsomes, K201 slowed the rate of SR Ca(2+) loading, s

205 Interestingly, microsomes labeled with a fluorescent marker were intern

206 ely 4-fold higher than that in camelina seed microsomes lacking CpuDGAT1.

207 from Schizosaccharomyces pombe and hog liver microsomes) leads to the hypothesis that PvdA catalysis

208 nal optimization of metabolic stability with microsomes led to the identification of 15, which displa

209 ism in human intestinal microsomes and liver microsomes make phosphoramidate 16 a prospective candida

210 rgets of atypical antibodies to liver/kidney microsome may lead to diagnostic tests for de-novo autoi

211 targeted to both the endoplasmic reticulum (microsomes) (mc CYP2E1) and mitochondria (mt CYP2E1).

212 (d)) for in vivo toxicology outcomes, scaled microsome metabolism/calculated logP for in vivo unbound

213 teins, metabolic stability using human liver microsomes, metabolism by human liver microsomes and hep

214 s in various subcellular fractions including microsomes, mitochondria, and lipid droplets; however, l

215 und that HCMV pUL37x1 is present in purified microsomes, mitochondria, and MAM fractions.

216 In rat brain microsomes, O(6)-demethylation was inhibited by ketocona

217 uld explain the in vitro covalent binding in microsomes observed across the species.

218 l with concomitant accumulation of TG in the microsome of Adfp-/- cells suggests that ADFP may facili

219 Microsomes of camelina (Camelina sativa) seeds engineere

220 ow levels of intrinsic clearance against the microsomes of four species, good bioavailability (55%) a

221 37- and 3-fold lower than that observed for microsomes of UGT1A4-overexpressing cells against nicoti

222 In the present study, microsomes of UGT2B10-overexpressing HEK293 cells exhibi

223 nium poly(vinylpyridine), DNA, and rat liver microsomes or bicistronically expressed human cyt P450 2

224 ed, apoE concentrated in a subclass of Golgi microsomes or Golgi-derived vesicles that co-migrated wi

225 of these IP3R mutants expressed in COS cell microsomes or in DT40 triple knock-out (TKO) cells did n

226 With rat hepatic microsomes or purified CPR, the presence of NADPH trigge

227 n in cells treated with either scrapie brain microsomes or purified, detergent-extracted PrP-res.

228 adioactive 17beta-estradiol with human liver microsomes or recombinant human cytochrome P450 isoforms

229 demonstrated that incubations of human liver microsomes or various human cytochrome P450 isoforms wit

230 sicles that co-migrated with apoB-containing microsomes or vesicles, respectively.

231 In addition to microsomes, Osm1 localizes to the mitochondrial intermem

232 ed SOAT1 and SOAT2 to a similar extent using microsomes prepared from cells disrupted under the stron

233 The assay is specific for FAAH given that microsomes prepared from cells expressing FAAH-S241A or

234 The assay is specific for FAAH given that microsomes prepared from cells expressing the inactive F

235 irus-infected cells and was also detected in microsomes prepared from HeLa cells.

236 components of technical chlordane, by liver microsomes prepared from male rats treated with corn oil

237 tion and aqueous two-phase separation of the microsome proteins located Rpg1 mainly in the cytosol bu

238 A rat liver microsome pseudostationary phase has been used for the o

239 sistent with previous studies of insect-cell microsomes, rat-human chimeric cells, and HeLa cells exp

240 ndole (HONH-AalphaC) formed with human liver microsomes, recombinant human UGT isoforms, and human he

241 In liver microsomes, reduced RNase-triggered gamma-carboxylation

242 ir with reconstituted CYP3A4 and human liver microsomes resulted in a covalent binding stoichiometry

243 ncubating LMP400 and LMP776 with human liver microsomes resulted in two major metabolites of each dru

244 scent substrates were applied to human liver microsomes, results suggested that there was at least on

245 with recombinant CYP4F2 and with human liver microsomes revealed a substrate K(m) of 8 to 10 microM.

246 3-diphenyl-propyl)-nicotinamide in rat liver microsomes revealed extensive oxidative metabolism and a

247 mitochondria but also occur in cytosolic and microsome-rich fractions.

248 phase I metabolite was formed by human liver microsomes, seven phase I and II metabolites were formed

249 Mutant ER microsomes show a decreased transfer of lipids to isolat

250 assays with yeast (Saccharomyces cerevisiae) microsomes showed a high specificity of RcsPLA2alpha for

251 d in compound 58 with substantially improved microsome stability and oral bioavailability, as well as

252 A rationale for the improvement in microsome stability and selectivity of inhibitors agains

253 any of the optimized compounds have improved microsome stability, and most are selective against huma

254 ited low cytotoxicity and satisfactory liver microsomes stability and plasma protein binding.

255 Finally, liver microsome studies revealed that (18)F-FTC-146 has a long

256 quirrel monkey imaging and human serum/liver microsome studies were performed to gain information abo

257 ocathepsin B is enriched in Golgi-containing microsomes, suggesting a role for the ADP-ribosylation (

258 bserved to assist folding in the presence of microsomes, suggesting that additional co-factors were i

259 pidly metabolized in rodents and human liver microsomes, suggesting the possibility of rapid in vivo

260 ombinant CYP4F2 (Supersomes) and human liver microsomes supplemented with NADPH converted VK1 to a si

261 metabolic stability in human and mouse liver microsomes, supporting its potential for in vivo use.

262 abolites after 1 h incubation in human liver microsomes system.

263 ys a good metabolic stability in human liver microsomes (t1/2 approximately 3 h and CLint = 3.5 mL/mi

264 type (WT) CYP2E1-expressing or ER(+) (mostly microsome-targeted) cells.

265 membrane permeable and more stable to liver microsomes than a similar non-statine-containing derivat

266 ve times higher conversion rate in dog liver microsomes than in human and monkey liver microsomes.

267 hly expressed enzyme in bovine and mouse RPE microsomes that displays significant reduction activity

268 In kidney microsomes the expression of UGT1A3 was below detection

269 However, when placed in ER-rich microsome, the mutant capsid retained its spherical stru

270 the substrate is incubated with human liver microsomes, the reaction is quenched, and the substrates

271 ation experiments, 8:2 FTOH was incubated in microsomes to determine the protein binding associated w

272 +)-methanandamide (MAEA) and FAAH expressing microsomes to evaluate the displacement activity of FAAH

273 ntified, and the extracts treated with liver microsomes to mimic physiological metabolism, with HPLC

274 and without (-) PLB in High Five insect cell microsomes to those of SERCA1 and SERCA2a in native skel

275 tabolizing mosquito P450s, as well as rodent microsomes, to measure labeling specificity, plus cytoch

276 tion activity of mouse, rat, and human liver microsomes toward the carcinogenic arylamine 4-aminobiph

277 Antismooth muscle (ASMA), antiliver kidney microsome type 1 (anti-LKM1), antiliver cytosol type 1 (

278 Vesicles immunoprecipitated from low density microsomes using antibodies directed against mTOR or RIC

279 Furthermore, the binding of [3H]MAEA to FAAH microsomes was abolished by selective FAAH inhibitors in

280 y at low pH, although stability toward liver microsomes was highly variable.

281 the covalent binding in rat, dog, and human microsomes was identified as a potential indicator for h

282 uronosyltransferase (EC 2.4.1.17) containing microsomes was isolated from rat liver and directly inje

283 its formation rate in a panel of human liver microsomes was strongly correlated with CYP3A4 content a

284 ioxidant activity (in liver, heart and brain microsomes) was analysed.

285 Using skeletal muscle microsomes, we examined the effects of BPA and TBBPA on

286 Using wild-type and Cyp3a knockout liver microsomes, we found that 4'-O-deacetylvinorelbine forma

287 kinetics of Xenopus CYP17 expressed in yeast microsomes were therefore examined in the absence and pr

288 Microsomes were used for the first time as sources of cy

289 r is explained by the retention of TG in the microsomes where VLDL is assembled.

290 inducing a net efflux of Ca(2+) from loaded microsomes, whereas BPA exhibited little or no activity

291 tivity of glucose-6-phosphatase in wild-type microsomes, whereas S>10K from countin(-) cells (cells w

292 nd (13)C6-APAP were incubated with rat liver microsomes, which are known to bioactivate APAP to the r

293 12 was rapidly metabolized by hepatic microsomes, which supports its topical use.

294 t it is efficiently processed in human liver microsomes with a half-life of 2 min.

295 Enrichment of microsomes with cholesteryl esters also inhibits cholest

296 After mixing microsomes with fluorescence-quenching agents and select

297 A is omega-oxidized in the presence of liver microsomes with initial omega-hydroxylation of 2-ClHA.

298 Treatment of rat liver microsomes with S-nitrosoglutathione caused S-nitrosylat

299 the isomerohydrolase activity in bovine RPE microsomes, with IC50 values of 0.5 and 0.2 mm, respecti

300 rce of 25OHD(3) hydroxylation by human liver microsomes, with the formation of 4beta,25-dihydroxyvita