ライフサイエンスコーパス: microsphere

1 lsion", prior to microencapsulation into the microspheres.

2 e CCL22, referred to here as Treg-recruiting microspheres.

3 hest payload was 0.56(+/-0.01) mumol SNAP/mg microspheres.

4 ere controlled by the bioerosion of the PLGA microspheres.

5 the field and the silver shells coating the microspheres.

6 chemoembolization using doxorubicin-eluting microspheres.

7 pancreatic cancer after treatment with (90)Y microspheres.

8 nation showed a foreign-body reaction to the microspheres.

9 rage stability when encapsulated in the PLGA microspheres.

10 orming from the exterior to the core of both microspheres.

11 before hepatic radioembolization with (90)Y-microspheres.

12 IVIVCs) for biodegradable controlled release microspheres.

13 compared with the in vitro release of these microspheres.

14 l of both the nano- and microfeatures of the microspheres.

15 les and non-porous (NP) and porous PLGA (PP) microspheres.

16 nsed PDMS microdroplets using vacuum-chucked microspheres.

17 ing beads, and radioembolization using (90)Y microspheres.

18 of a closely packed lattice of monodispersed microspheres.

19 during release from commonly used polymeric microspheres.

20 d membrane bilayer supported on 3 mum silica microspheres.

21 l solution of small volume to form embryonic microspheres.

22 ow it causes drug release from biodegradable microspheres.

23 measured by direct analysis of the recovered microspheres.

24 gy is the Luminex MagPix platform using xMAP microspheres.

25 ce was performed with 300-500-mum Embosphere microspheres.

26 ive hydrogel carrier and drug-loaded polymer microspheres.

27 the organic solvent and harden the embryonic microspheres.

28 artery perfusion, quantified by fluorescent microspheres (206% increase in large tumors) or high-res

29 ary branch of the left ECA using Embozene(R) Microspheres - 250 mum in size before endoscopic tumour

30 lver-coated Poly(methyl methacrylate) (PMMA) microspheres (50 mum diameter) into tailored patterns.

31 w that acute aqueous exposure to polystyrene microspheres (8 mum) with different surface coatings had

32 exists for the treatment of CRLM with resin microsphere (90)Y radioembolization.

33 Compared with (99m)Tc-MAA-microspheres, (99m)Tc-HSA-microspheres are likely more r

34 of surface functionalization techniques, one microsphere acts as a dynamic reference, compensating fo

35 eplaced with glucose 5% (G5) for (90)Y-resin microsphere administration.

36 , etc.) in the form of pellets, powders, and microspheres after suitable modifications in sample hand

37 were randomly assigned to embolization with microspheres alone (Bead Block [BB]) or loaded with doxo

38 l compares the outcome of embolization using microspheres alone with chemoembolization using doxorubi

39 ble thickness in the vicinity of an embedded microsphere and allow for adiabatic nano-focusing of gap

40 the calcite-solution interface with a silica microsphere and to measure Derjaguin-Landau-Verwey-Overb

41 nanomaterials, carbon nano tubes, polymers, microspheres and biomaterials have been evoked.

42 For the group with nonradiopaque microspheres and contrast material, retained tumoral con

43 that the microgels form a corona around the microspheres and induce a soft repulsive shoulder that g

44 nthesis and surface functionalization of MIP microspheres and nanoparticles are well established, the

45 FM cantilevers were functionalized with PMMA microspheres and probed against C. albicans cells immobi

46 e characteristics of the prepared naltrexone microspheres and the reference-listed drug (Vivitrol(R))

47 combination of a single dose each of plastic microspheres and vascular endothelial growth factor rece

48 ared genotypes using sequencing, fluorescent microsphere, and quantitative polymerase chain reaction

49 ew types of surface modified barium alginate microspheres, and evaluated their inflammatory propertie

50 f molecules including dextran, streptavidin, microspheres, and lentivirus particles.

51 release of leuprolide from acid-capped PLGA microspheres appeared to be controlled initially by eros

52 of up to five different types of DNA-coated microspheres are adjusted to kinetically control a highe

53 The microspheres are attached to cell-free nanofibrous polym

54 Indeed, data suggest that Treg-recruiting microspheres are capable of overcoming the immunological

55 Hence, the microspheres are considered promising as an additive to

56 vior of direct ink write structures, polymer microspheres are good candidates for shape memory elasto

57 d with (99m)Tc-MAA-microspheres, (99m)Tc-HSA-microspheres are likely more resistant to degradation ov

58 n this work, Li3V2(PO4)3@carbon hierarchical microspheres are prepared by a solvothermal reaction and

59 Alginate nano/microspheres are produced by emulsification/internal gel

60 clusion, this study shows that our polymeric microspheres are suitable as sustained release formulati

61 ular, three-dimensional array of transparent microspheres arranged like the atoms in a diamond crysta

62 g analysis of gold nanoparticle-loaded latex microspheres as a signal-amplified hybridization tag, wh

63 531 patients treated with glass-based (90)Y microspheres at 8 institutions, making it the largest (9

64 ne (PS) and poly(methyl methacrylate) (PMMA) microspheres based entirely on their difference in mecha

65 re used for the detection of these toxins: a microsphere-based immunoassay that offered an estimation

66 ability of in vitro release tests to predict microsphere behavior in vivo and develop more meaningful

67 s were first deposited on monodisperse Fe3O4 microspheres by a sol-gel method.

68 lsions were encapsulated in calcium-alginate microspheres by ionic gelation.

69 n poly(lactic-co-glycolic acid) 50:50 (PLGA) microspheres by using a solid-in-oil-in-water emulsion s

70 ifferences (bi-phasic vs tri-phasic) between microspheres can affect the development and predictabili

71 er saturated nanocellulose cellulose aerogel microspheres can be easily removed by filtration or cent

72 s can be squeezed and washed out and aerogel microspheres can be reused.

73 view board approval is required before glass microspheres can be used under a compassionate-use or re

74 ld combine the light guiding properties of a microsphere chain with the light localizing properties o

75 pic probability-density functions describing microsphere clustering to provide realistic simulation u

76 , several simple physical systems, including microspheres, coacervate droplets and phospholipid membr

77 Whole Wolbachia or microspheres coated with a synthetic Wolbachia lipopepti

78 The kinetics of water uptake into the microspheres coincided with the drug release profiles fo

79 investigation include tunable, bioresorbable microspheres composed of chitosan or poly(ethylene glyco

80 pregulated on activated myofibroblasts, into microspheres composed of hydrophilic multi-block copolym

81 In this manuscript, we describe microspheres composed of poly(lactic-co-glycolic acid) (

82 measurements of the 2% SPIO-labeled yttrium microsphere concentration were well correlated with know

83 vel A IVIVC can be established for polymeric microspheres containing another small molecule drug with

84 Here, we show that chains of optical microspheres containing gold nanoparticles in their evan

85 been established and validated for polymeric microspheres containing risperidone (a practically water

86 observed with incremental increases of SPIO microsphere content.

87 nses over the study period compared to blank microsphere control CGM implants.

88 It was found that the microspheres could be moved at a max velocity of 3200 mu

89 ically single down-shifting and upconversion microspheres, crystalline microplates, and color-barcode

90 ars) underwent TACE with doxorubicin-eluting microspheres (DEB) (hereafter, DEB-TACE) and subsequentl

91 itinib, was released from degradable polymer microspheres delivered from the surfaces of FDA-approved

92 A chitosan-based microsphere delivery system has been fabricated for cont

93 ased measurements of 2% SPIO-labeled yttrium microsphere delivery were well correlated with infused d

94 embolization, increasing the specificity of microsphere delivery, and reducing the lung-shunt fracti

95 SNRs of radiopaque microsphere deposition increased after TAE on multidetec

96 An analysis of microsphere deposition patterns within the gastrointesti

97 was superficial to areas of abnormally high microsphere deposition.

98 ribe elastic hexadecapoles formed by polymer microspheres dispersed in a liquid crystal, a nematic fl

99 mucosa performed on the basis of microscopic microsphere distribution confirmed that (90)Y dosimetry

100 e carbon layer on the surface of Li3V2(PO4)3 microspheres during the annealing process.

101 rpose To assess the visibility of radiopaque microspheres during transarterial embolization (TAE) in

102 The data indicate that the betalg/Lyso microspheres effectively improved the stability of D3, w

103 Administration of Treg-recruiting microspheres effectively mitigated the symptoms of DED a

104 ich facilitates manipulation of the metallic microspheres efficiently without compromise in positioni

105 adation and drug release mechanism from PLGA microspheres embedded in a PVA hydrogel.

106 ytes are composed of silica nanoparticles in microspheres embedded in gelatin, both are low refractiv

107 ng capacity and high selectivity of the MMIP microspheres enabled efficient extraction of cloxacillin

108 PLGA 50/50 microspheres encapsulating ~5% w/w leuprolide were prepa

109 en contrast material was added to radiopaque microspheres, except for additional image attenuation du

110 e 3D carbon wrapped Li3V2(PO4)3 hierarchical microspheres exhibit high rate capability and excellent

111 Furthermore, the microspheres exhibited high energy efficiency and good c

112 se oxide octahedral molecular sieve chitosan microspheres (Fe3O4@OMS-2@CTS) on anaerobic and aerobic

113 uiding tool in development of new generation microspheres for cell encapsulation therapy.

114 ically feasible process to produce polymeric microspheres for sustained-release delivery of protein d

115 refore, we developed biodegradable polymeric microspheres for the sustained release of proteinaceous

116 reatment of neuroendocrine tumours and (90)Y-microspheres for the treatment of hepatic tumours.

117 o UV-light, vitamin D3 has been entrapped in microspheres formed by bovine protein beta-lactoglobulin

118 Immunization of rats with the leading microsphere formulation showed more robust and long-last

119 re, two poly(lactic-co-glycolic acid) (PLGA) microsphere formulations encapsulating the model steroid

120 Both microsphere formulations exhibited erosion-controlled re

121 These new microsphere formulations may be useful for site-specific

122 he efficacy of a long-term, non-invasive gel/microsphere (GMS) eye drop for glaucoma.

123 adiopaque microspheres in saline (radiopaque microsphere group), 70-150-mum radiopaque microspheres i

124 olization of liver malignancies with (166)Ho-microspheres has been shown to be safe in a phase 1 dose

125 rrelations (IVIVCs) for parenteral polymeric microspheres has been very challenging, due to their com

126 ted with (90)Y radioembolization using glass microspheres has demonstrated promising survival outcome

127 Because glass microspheres have a higher activity per particle, they c

128 Because resin microspheres have a lower activity per particle, more pa

129 In addition, resin microspheres have been approved by the U.S. Food and Dru

130 ostructures, such as cubes, flower-like, and microspheres, have been extensively synthesized by a sim

131 A fluorescent microsphere hybridization assay was designed that was ca

132 ons included RT-PCR for Zika virus, and both microsphere immunofluorescent and seroneutralisation ass

133 These data favor the use G5 for (90)Y-resin microsphere implantation in daily practice.

134 efractory CRLM were treated with resin (90)Y-microspheres in a prospective phase II clinical trial.

135 es to determine the position and diameter of microspheres in a spiral microfluidic channel under vari

136 material group), and 70-150-mum radiolucent microspheres in contrast material (nonradiopaque microsp

137 ue microsphere group), 70-150-mum radiopaque microspheres in contrast material (radiopaque microspher

138 of periodically driven and optically tweezed microspheres in fluid and find a rich variety of dynamic

139 e motion of negatively charged, carboxylated microspheres in mucus from pregnant patients was signifi

140 hemotherapy with SIRT using yttrium-90 resin microspheres in patients with metastatic colorectal canc

141 mbolic agent injected: 70-150-mum radiopaque microspheres in saline (radiopaque microsphere group), 7

142 icting the in vivo performance of naltrexone microspheres in the investigated animal model.

143 We study the phase behavior of microspheres in the presence of poly(N-isopropylacrylami

144 Radioembolization with (166)Ho-microspheres induced a tumor response with an acceptable

145 of 5% of total liver, were 8 x 10 ten-micron microspheres infused with a 29 G needle directly into th

146 ucted during an intravenous perflutren lipid microsphere infusion.

147 Microspheres inhaled into the gill chamber had a small b

148 A well-defined hydrogel/microsphere interface was observed.

149 For the 25 kDa microspheres, internal pore formation and swelling occur

150 oral angiography and infusion of (90)Y-resin microspheres into arteries supplying part of the gastric

151 ghly-targeted delivery of brimonidine-loaded microspheres into the supraciliary space using a microne

152 tive index and temperature), while the other microsphere is functionalized to detect a specific inter

153 lease testing of parental controlled release microspheres is an essential step in controlling quality

154 l injection of radioactive yttrium-90-loaded microspheres is increasingly used for the treatment of p

155 In the model, Brownian rotation of the microspheres is taken into account, which proved to be a

156 ce between naltrexone and risperidone loaded microspheres is their respective bi-phasic and tri-phasi

157 micking fluid suspensions of 3 mum absorbing microspheres, it was discovered that the perceived heter

158 MR imaging R2* measurements of yttrium microspheres labeled with 2% SPIO can quantitatively dep

159 y means of a combination of a cost-effective microsphere lithography technique and subsequent dry/wet

160 d to incorporate the chitosan/hydroxyapatite microspheres-loaded with AL (CH/nHA-AL) into poly(L-lact

161 ly degenerate boundary conditions, the solid microspheres locally perturb the alignment of the nemati

162 Histologic sections were used to map microsphere location, and a microdosimetric evaluation w

163 The in vivo release of Tr-A from microspheres made of a higher molecular weight, ester en

164 -adhesive poly(n-butyl acrylate) [poly(nBA)] microspheres matrix, which was synthesized via facile mi

165 l was to determine what effect the number of microspheres may have, if any, on tumor control in (90)Y

166 The development of essential oil microspheres may help to avoid these problems.

167 he correlation between (99m)Tc-MAA and (90)Y-microsphere mean TBR was low.

168 tion agreed well with those with fluorescent microspheres (mean difference, 4.2%; 95% LOA, +/-20.5%).

169 it-time ultrasonography (US) and fluorescent microsphere measurements of hepatic arterial fraction we

170 To assess the impact of polystyrene microspheres (micro-PS) on the physiology of the Pacific

171 Obtained results make this hybrid microsphere-microfluidic approach to dengue detection a

172 lly embedding CTGF- or TGFbeta3-encapsulated microspheres (microS) to reconstruct the regionally vari

173 eep temporal artery as a potential route for microspheres migration.

174 For the 25 kDa microspheres, minimal water uptake was observed in the e

175 Minocycline microspheres (MMs) are being used to treat residual infl

176 sm, as demonstrated by reduced intracellular microsphere movement, and an approximate halving of cell

177 Neither microspheres nor natural sediments altered the crab's re

178 mbined utilization of PDMS microdroplets and microspheres not only enables the realization of microsp

179 imulations were performed with average tumor microsphere-number densities from 200 to 70,000 spheres/

180 was used to determine whether differences in microsphere-number density affected common tumor-dose me

181 ume histogram also decreased with decreasing microsphere-number density in all tumors.

182 Differences in microsphere-number density may have an effect on microsc

183 Decreasing the microsphere-number density resulted in a decrease in D70

184 Although D70 was decreased at a low microsphere-number density, one can compensate for decre

185 Finally, the microspheres obtained showed significant antimicrobial e

186 in vitro release profiles of the naltrexone microspheres obtained using USP apparatus 4.

187 ucting CaO2 core-mesoporous shell-CaO2 shell microspheres (OCRMs).

188 ring the electrochemical reaction due to the microspheres of small nanoparticles.

189 , quality of life, and quantification of the microspheres on SPECT and MRI.

190 Large specific surface area of microspheres, on the other hand, has secured an importan

191 tched saline; PE and SU groups received only microspheres or SU5416, respectively.

192 be used to induce rapid NO release from the microspheres over several hours.

193 study, poly(dopamine-quinone chromium (III))-microspheres (PDQCM) were used for the modification of g

194 th factor receptor antagonist in polystyrene microspheres (PE) + tyrosine kinase inhibitor SU5416 (SU

195 oembolization as a function of the number of microspheres per unit volume in tumor.

196 combined were related to reference standard microsphere perfusion measurements (PMICRO), as follows:

197 oronary arteries combined were compared with microsphere perfusion measurements by using regression,

198 most identically sized dye-doped polystyrene microspheres placed on adjacent holes at the tip of a mi

199 For this purpose, a nanocomposite microsphere platform was developed for selective intra-a

200 icrospheres in contrast material (radiopaque microsphere plus contrast material group), and 70-150-mu

201 ospheres in contrast material (nonradiopaque microsphere plus contrast material group).

202 ere, we incorporate two different gas filled microsphere pore formers to evaluate the effect of shell

203 The uniform size distribution of the acrylic microspheres promoted homogeneity of the immobilized SO

204 releasing PLGA poly(lactic-co-glycolic acid) microsphere/PVA (polyvinyl alcohol) hydrogel composite c

205 The SMMs and QD-incorporated spore microspheres (QDSMs) were characterized by using transmi

206 cy, and prognostic factors for (90)Y-yttrium microsphere radioembolization of unresectable liver meta

207 We embedded resonant polar dielectric microspheres randomly in a polymeric matrix, resulting i

208 Motion of the microsphere reflected underlying forces exerted by the m

209 ver fibrosis how the subcutaneously injected microspheres released pPB-HSA into both plasma and fibro

210 The surface layer of the microspheres remained intact whereas swelling, and degra

211 There are 2 types of (90)Y microspheres: resin and glass.

212 ing for free fluid and cellular exchange and microsphere retrieval during release.

213 Comparison between resin and glass microspheres revealed higher but not statistically signi

214 Comparison between resin and glass microspheres revealed no significant survival difference

215 apatite (PLLA/nHA) matrix to prepare a novel microspheres-scaffold hybrid system (CM-ALs) for drug de

216 A microspheres-scaffold-based release system containing AL

217 (90)Y-microsphere selective internal radiation therapy (SIRT)

218 Molecularly imprinted porous polymer microspheres selective to Alternaria mycotoxins, alterna

219 ivering a calculated lobar activity of (90)Y microspheres selectively to treat a tumor involving 1 or

220 The obtained rhGM-CSF microspheres showed a satisfied release profile with the

221 The r2* relaxivity for each of four microsphere SPIO compositions was determined from 32 pha

222 ly distributed within each liver; increasing microsphere SPIO content produced marked signal voids.

223 With this instrument format and fluorescent microsphere standards, we obtain analysis rates of 100K/

224 Although the microspheres still contained protein at day seven, pPB-H

225 By contrast, the higher Tg microsphere structures exhibit reduced compression set w

226 The lower Tg microsphere structures exhibit substantial compression s

227 Here, we report the development of a microsphere supported-biomembrane platform enabling char

228 the immobilized SO reagent molecules on the microspheres' surfaces, thereby enhanced the sensing res

229 In addition, microsphere swelling reduced glucose transport through t

230 3D LiMn0.75Fe0.25PO4/reduced graphene oxide microspheres synthesized by one-step salt-assisted spray

231 llary blood flow was measured by the colored microsphere technique.

232 through degradable polymer microspheres (TRI microspheres; TGF-beta1, Rapamycin (Rapa), and IL-2).

233 4 method was capable of discriminating PLGA microspheres that are equivalent in formulation composit

234 ion (IVIVC) can be established for polymeric microspheres that are equivalent in formulation composit

235 ricate drug-loaded multimodal MRI/CT visible microspheres that included both gold nanorods and magnet

236 rocess for encapsulation of proteins in PLGA microspheres that showed low burst release was developed

237 The aerogel microspheres that were saturated with stripping solution

238 er optimizing the alginate concentration for microspheres, the combined osteogenic and mineralization

239 ((99m)Tc-MAA) SPECT for (90)Y-labeled resin microsphere therapy (radioembolization) by comparing upt

240 Glass microspheres thus may be more suitable when early stasis

241 Resin microspheres thus may be preferable for larger tumors an

242 ospheres not only enables the realization of microsphere-tipped PDMS micropillars on non-flat, highly

243 us of living Toxoplasma gondii by adhering a microsphere to the surface of an immobilized parasite.

244 nd torsion balance using highly birefringent microspheres to directly and simultaneously measure the

245 polyplexes are encapsulated in biodegradable microspheres to enable controllable two-stage (polyplexe

246 ethylene) glycol diacrylate (PEGDA) hydrogel microspheres to enable high sensitivity VEGF detection i

247 iation therapy (SIRT) using yttrium-90 resin microspheres to standard fluorouracil, leucovorin, and o

248 ever, the off-target diversion of yttrium-90 microspheres to tissues other than the tumor may lead to

249 media on release from leuprolide-loaded PLGA microspheres to understand the influence of external pH,

250 al trunk of C57BL6 adult mice with polyester microspheres, to ensure a bilateral and distal distribut

251 iled from 8 institutions for all (90)Y glass microsphere treatments for colorectal liver metastases.

252 inducing factors through degradable polymer microspheres (TRI microspheres; TGF-beta1, Rapamycin (Ra

253 act phenomenon not seen on the macroscale: a microsphere undergoes a full conformal penetration into

254 Embozene(R) is a new neuroembolizing microsphere used to reduce intraoperative bleeding for h

255 A single administration of these microspheres using a hollow microneedle was performed in

256 on many individual biomolecules tethered to microspheres using a single collimated laser beam.

257 e cells into hollow mesoporous bio-hydrochar microspheres via hydrothermal carbonization method.

258 conundrum, a porous biodegradable polymeric microsphere was investigated as a potential scaffold for

259 The internal structure of the PLGA microspheres was evaluated using low temperature scannin

260 Encapsulation yield (%) of resistant starch microspheres was in the range of 43.01-48.46.

261 In vitro release of the risperidone microspheres was investigated using different release te

262 vival difference between both types of (90)Y microspheres was observed in any subgroups of patients w

263 The repartition of microspheres was studied by angiographic and histologica

264 e system containing AL-encapsulated chitosan microspheres was successfully fabricated in this study.

265 mization) on crosslinking and bioactivity of microspheres was tested.

266 st agent solution (perflutren protein-type A microspheres) was injected via the nephrostomy tube.

267 For the 7 kDa microspheres, water uptake occurred simultaneously with

268 approximately 2-3 times that of the initial microsphere weight for both formulations.

269 The microspheres were administered to 41 hepatocellular carc

270 ylated (COOH) and aminated (NH2) polystyrene microspheres were distributed differently across the gil

271 The microspheres were evaluated regarding size, shape, encap

272 The recovered release media and microspheres were examined for released drug, polymer mo

273 To test this hypothesis, brimonidine-loaded microspheres were formulated using poly(lactic acid) (PL

274 No advantages for drug-eluting microspheres were found.

275 Microspheres were heterogeneously distributed within eac

276 The microspheres were incubated at 37 degrees C up to 56days

277 5, 10, 15, or 20 mg 2% SPIO-labeled yttrium microspheres were infused into 24 rats (six rats per gro

278 The pharmacokinetics of the naltrexone microspheres were investigated using a rabbit model.

279 Microspheres were modified using proprietary polyallylam

280 hydrophilic, deformable, and non-aggregated microspheres were mono-disperse and roughly 25 um in siz

281 Two types of microspheres were prepared with different molecular weig

282 Results Radiopaque microspheres were qualitatively visualized within tumor

283 Iron oxide surface patches on latex microspheres were selectively wetted with liquid lipid,

284 The microspheres were successfully infused through catheters

285 Molecularly imprinted polymer microspheres were synthesized by precipitation polymeriz

286 MMIP microspheres were synthesized using a core-shell techniq

287 The hollow microspheres were used as microreactors and carriers for

288 Conclusion Radiopaque microspheres were visible with all imaging modalities an

289 This study investigated if calcium phosphate microspheres, which have remineralizing properties, coul

290 f the whispering gallery modes (WGMs) of the microspheres while also providing a robust and easy to m

291 smooth spherical morphology of the poly(nBA) microspheres with a narrow particles size distribution f

292 as successfully entrapped in the betalg/Lyso microspheres with an encapsulation efficiency of 90.8+/-

293 The ability to generate microspheres with controlled morphology and unusual stre

294 onally equivalent formulations of naltrexone microspheres with different release characteristics were

295 been established and validated for polymeric microspheres with different release characteristics.

296 tra-light cellulose nanofibril based aerogel microspheres with high porous structure and water storag

297 We used microspheres with known diameters to validate the sub-mi

298 ate individual 15 mum lanthanide luminescent microspheres with standard deviations of 1.38 and 1.75 m

299 Slow pulsatile administration of (90)Y-resin microspheres with WFI is associated with a low rate of s

300 akup of cylindrical porous structures porous microspheres within the fiber core.Porous polymer fibers