ライフサイエンスコーパス: microstimulation

1 somatosensory cortex (S1) via intracortical microstimulation.

2 rtex in behaving monkeys using intracortical microstimulation.

3 nd in turn impaired thresholds for detecting microstimulation.

4 ntal eye field (FEF) following intracortical microstimulation.

5 in motor cortex as assessed by intracortical microstimulation.

6 nsory areas of their brains using electrical microstimulation.

7 on affects saccadic eye movements during FEF microstimulation.

8 ned how discriminability was affected by FEF microstimulation.

9 rally relevant," long-duration intracortical microstimulation.

10 mically activated by right posterior insular microstimulation.

11 to optical imaging and patterned electrical microstimulation.

12 recordings of neuronal activity and cortical microstimulation.

13 ght cells to weak single pulse intracortical microstimulation (20 microA) through a nearby electrode

14 nalysis of EMG activity evoked by repetitive microstimulation (200 Hz, 500 ms) of primary motor corte

15 acellular current injection or extracellular microstimulation adjacent to the cell body.

16 response to touch following spike-triggered microstimulation, along with decreased neural variabilit

17 NRA neurochemical microstimulation also generated vocalizations (guttural

18 At such OT sites, AGF microstimulation also sharpened auditory receptive field

19 (Callithrix jacchus) by using intracortical microstimulation and an architectonic analysis.

20 ssed these questions using singing-triggered microstimulation and chronic recording methods in the si

21 s obtained from causality-based experiments (microstimulation and inactivation).

22 nd movement patterns evoked by intracortical microstimulation and injected with the retrograde tracer

23 tion pathways, particularly as elucidated by microstimulation and lesion studies; (iii) top-down modu

24 Electrical microstimulation and more recently optogenetics are wide

25 ation of neural circuitry through electrical microstimulation and optogenetic techniques is important

26 ation of neural circuitry through electrical microstimulation and optogenetic techniques is important

27 causal link with heading perception, we used microstimulation and reversible inactivation techniques

28 We investigated RN motor map maturation with microstimulation and RST cervical enlargement projection

29 Experiments using microstimulation and single-neuron electrophysiology sug

30 Together, our microstimulation and single-neuron results suggest that

31 Microstimulation and tracer injection sites were verifie

32 Microstimulation and trans-synaptic tracing identified t

33 criminability was apparent immediately after microstimulation and was reliable within 40 ms of micros

34 ion of PPC based on intracortical long-train microstimulation, and they identify parts of cortical ne

35 Here we show that electrical microstimulation applied to gaze control circuitry in th

36 This suggests multichannel microstimulation as a viable means of sensorizing neural

37 from pulvinar neurons that we identified by microstimulation as receiving input from SC and/or proje

38 ral hours, here we used transient electrical microstimulation at different periods while monkeys perf

39 Microstimulation at PW4 evoked contralateral wrist, elbo

40 can be signaled through phasic intracortical microstimulation at the onset and offset of object conta

41 In contrast, microstimulation at the same recording sites does bias d

42 ctural dynamics, two important approaches to microstimulation at this scale, are briefly reviewed.

43 By combining such optical recordings with microstimulation at two well-separated sites of M1, we d

44 To test this, we implemented a microstimulation-based neuroprosthesis that rats used to

45 the spinal cord, we synchronized intraspinal microstimulation below the injury with the arrival of fu

46 In one monkey, microstimulation biased speed judgments toward the prefe

47 on by GCaMP3 were confirmed by intracortical microstimulation but were more difficult to detect using

48 that the interaction of expected reward with microstimulation can be explained if expected reward mod

49 We argue that caudate microstimulation can differentially increase stimulus va

50 Electrical microstimulation can establish causal links between the

51 ent with the winner-take-all hypothesis, (2) microstimulation can influence direction estimates even

52 ld traversed by the target indicate that dSC microstimulation can interfere with signals encoding the

53 However, how microstimulation changes the neural substrate is still n

54 rd trials that were accompanied by phasic SN microstimulation compared with reward trials without sti

55 n its differential response to intracortical microstimulation compared with the caudal whisker area (

56 At the same time, AGF microstimulation decreases the responsiveness of OT neur

57 Although microstimulation delivered through multiple implanted el

58 In addition, microstimulation delivered to forepaw VPL antidromically

59 uided by spatiotemporal patterns of cortical microstimulation delivered to primary somatosensory cort

60 Even on trials in which microstimulation did not induce a preferred direction ch

61 Microstimulation did not reduce overall confidence in th

62 d unit-pair mutual information, while random microstimulation did not.

63 Microstimulation drove the eyes accurately to the site o

64 CIP-microstimulation during fMRI further suggests that CIP p

65 ining reversible inactivation and electrical microstimulation during fMRI provides a detailed view of

66 ure selectivity and then employed electrical microstimulation during functional magnetic resonance im

67 t powerful motion stimuli available, and (3) microstimulation effects can be elicited when a manual r

68 FEF microstimulation enhanced the PLR to probes presented wi

69 Microstimulation even perturbed the percept of certain o

70 Locations in S2 spinal cord, where microstimulation evoked a distal/proximal colon pressure

71 New microstimulation experiments on awake, behaving monkeys

72 se the normalization model and recording and microstimulation experiments to show that the attention

73 conducted electrophysiological recording and microstimulation experiments to test the hypothesis that

74 In microstimulation experiments, we activated clusters of M

75 netics as a viable alternative to electrical microstimulation for the precise dissection of the corti

76 in the spinal intact anesthetized cat where microstimulation generates selective contraction of the

77 pressure and that regions are present where microstimulation generates small reductions in urethral

78 While microstimulation had no effect on the percept of many no

79 For over a century, electrical microstimulation has been the most direct method for cau

80 High-frequency repetitive microstimulation has been widely used as a method of inv

81 High-frequency, long-duration intracortical microstimulation (HFLD-ICMS) is increasingly being used

82 high-frequency, long-duration intracortical microstimulation (HFLD-ICMS) to primary motor cortex (M1

83 This study used intracortical microstimulation (ICMS) and electromyographic (EMG) reco

84 limb movement responses during intracortical microstimulation (ICMS) and movements of the forelimb on

85 Intracortical microstimulation (ICMS) and recording of evoked jaw and

86 into proportional subthreshold intracortical microstimulation (ICMS) during hours of unrestrained vol

87 nt with this general function, intracortical microstimulation (ICMS) in the PM of sufficient frequenc

88 Intracortical microstimulation (ICMS) is a powerful tool to investigat

89 icial tactile feedback through intracortical microstimulation (ICMS) of the primary somatosensory cor

90 Intracortical microstimulation (ICMS) studies have provided two contra

91 cortex was conducted by using intracortical microstimulation (ICMS) techniques, as well as low-imped

92 We used intracortical microstimulation (ICMS) to determine the representation

93 ws (Tupaia belangeri) by using intracortical microstimulation (ICMS), corticospinal tracing, and deta

94 lysis combining layer-specific intracortical microstimulation (ICMS), CSD analysis, and pharmacologic

95 derived using high-resolution intracortical microstimulation (ICMS).

96 areas of a "decoder" rat using intracortical microstimulation (ICMS).

97 tactile sensation produced by intracortical microstimulation (ICMS).

98 We find that microstimulation improves performance in a spatially sel

99 rsive) saccadic eye movements were evoked by microstimulation in anterior SC, followed by a smooth pr

100 rtant implications for the use of electrical microstimulation in both experimental and clinical setti

101 Finally, microstimulation in CGp following risky choices promoted

102 havioral thresholds for detecting electrical microstimulation in different cortical areas in two monk

103 Neurochemical microstimulation in different parts of the midbrain peri

104 e was evoked to one of the moving targets by microstimulation in either the frontal eye field (FEF) o

105 d to the human median nerve via percutaneous microstimulation in four intact subjects and via implant

106 Anal sphincter relaxation was evoked by microstimulation in more restricted locations in S2 spin

107 rature on the effects of cortical electrical microstimulation in perceptual and decision-making tasks

108 duce neural plasticity [10, 11], and caudate microstimulation in primates has been shown to accelerat

109 Prolonged microstimulation in RF, a larger anterior subregion of v

110 White matter microstimulation in sagittal slices (near the ventricula

111 In this study, we used electrical microstimulation in select nuclei of the avian song syst

112 Moreover, delivering microstimulation in the caudate during the reinforcement

113 arm movements can be elicited by electrical microstimulation in the deep layers of the lateral SC an

114 These perturbations are induced by brief microstimulation in the deep superior colliculus (dSC).

115 Electrical microstimulation in the forebrain gaze control area, the

116 were evoked after contralateral intraspinal microstimulation in the gray matter (cISMS; 300 muA maxi

117 eases in bladder pressures were generated by microstimulation in the intermediolateral region, in the

118 ley evoked in the sural nerve by intraspinal microstimulation in the L4/5 spinal segment was increase

119 this, we measured the effects of electrical microstimulation in the lateral intraparietal area (LIP)

120 cts of optogenetic activation and electrical microstimulation in the lateral intraparietal area durin

121 re cell-targeted optogenetics and electrical microstimulation in the macaque monkey brain to function

122 Here, we show that electrical microstimulation in the monkey caudate nucleus influence

123 We show that electrical microstimulation in the motion-sensitive middle temporal

124 We show that song-triggered microstimulation in the output nucleus of the AFP induce

125 Here, we report that microstimulation in the prefrontal cortex (PFC) modulate

126 of invisible moving targets using electrical microstimulation in the prefrontal cortex.

127 Microstimulation in the right entorhinal area during lea

128 t vergence eye movements can be evoked using microstimulation in the rSC.

129 e is known about the influence of electrical microstimulation in the SC on the initiation and traject

130 Here, we applied microstimulation in the SN of 11 patients undergoing dee

131 We recorded from single units and delivered microstimulation in the striatum of rhesus monkeys perfo

132 f the interceptive saccade is perturbed by a microstimulation in the superior colliculus.

133 ncreases in urethral pressure were evoked by microstimulation in the ventrolateral ventral horn, but

134 Notably, microstimulation in this subzone, but not elsewhere in t

135 reas' activity following thalamic electrical microstimulation in tree shrews, using optical imaging a

136 Microstimulation in V1 elicited gamma-oscillations in V4

137 s and that attention increased the effect of microstimulation in V1 on the firing rates of MT neurons

138 Here, we use electrical microstimulation in V1 paired with recording in MT to pr

139 1 elicited gamma-oscillations in V4, whereas microstimulation in V4 elicited alpha-oscillations in V1

140 AGF microstimulation increases the responsiveness of OT neur

141 ain mapping experiments involving electrical microstimulation indicate that the primary motor cortex

142 xperimentally, we found that spike-triggered microstimulation induced cortical plasticity, as shown b

143 perceptual responses elicited by intraneural microstimulation (INMS) of single mechanoreceptive affer

144 e microneurographic technique of intraneural microstimulation (INMS) we stimulated groups of nerve fi

145 this question have proven difficult because microstimulation interferes with electrophysiological re

146 Typically, microstimulation is applied to local brain regions as a

147 Electrical microstimulation is known to induce neural plasticity [1

148 difference in effectiveness of intracortical microstimulation is that long trains activate much large

149 Electrical microstimulation is used widely in experimental neurophy

150 both direct neural recordings and electrical microstimulation, Joshi et al. (2016) show that locus co

151 omly selected for perilesional intracortical microstimulation mapping and tissue sampling for Western

152 esult of NPT, as revealed with intracortical microstimulation mapping.

153 uscle activity patterns elicited by cortical microstimulation matched those extracted from natural mo

154 e trial, indicating that signals produced by microstimulation may be subject to active 'gating'.

155 Microstimulation may cause cortical changes that could e

156 Intracortical microstimulation, Micro-PET and histological analysis we

157 pped the stimulus locations and measured how microstimulation modulated these contrast response funct

158 When the microstimulation moves the eyes in the direction opposit

159 Microstimulation never directly evoked saccades, nor did

160 Unitary EPSPs, evoked by microstimulation of a single ganglion cell, were measure

161 to keep their gaze fixed, we tested whether microstimulation of a specific location in the SC spatia

162 Consistent with this observation, microstimulation of AL, but not ML, systematically biase

163 In freely moving rats, microstimulation of basolateral amygdala at intensities

164 Microstimulation of direction columns in the middle temp

165 We found that microstimulation of face patches caused increased fMRI a

166 We asked how electrical microstimulation of face patches in macaque inferotempor

167 We combined electrical microstimulation of functionally specific groups of neur

168 visual stimuli result from focal electrical microstimulation of gaze control centres in monkeys.

169 gical progress it has been demonstrated that microstimulation of infragranular cortical layers with p

170 ebellum to localize synchronous responses to microstimulation of its cortical layers and reveal the c

171 Microstimulation of layer VI in "matched" (homologous) b

172 ion, we trained animals to detect electrical microstimulation of local V1 sites.

173 y electrophysiology using chronic electrical microstimulation of macaque VTA (VTA-EM).

174 Weak microstimulation of many sites in the supplementary eye

175 Combining patterned optical microstimulation of MOB with in vivo electrophysiologica

176 Electrical microstimulation of MST frequently biased the monkeys' d

177 In the fine task, we find that electrical microstimulation of MT does not affect perceptual decisi

178 pressure, and timing--through intracortical microstimulation of primary somatosensory cortex.

179 We show that the microstimulation of sensorimotor cortex induces Fos and

180 he same subject in conjunction with periodic microstimulation of single mechanoreceptive afferents wh

181 Here we show that microstimulation of spatially aligned FEF representation

182 animals to become expert at the detection of microstimulation of specific V1 sites that corresponded

183 Microstimulation of the AGF enhanced the visual and audi

184 ation throughout the face-processing system; microstimulation of the body patches gave similar result

185 termine which neural elements are excited by microstimulation of the central nervous system.

186 Both 1 and 25 Hz microstimulation of the contralateral insula indicated t

187 We examined whether microstimulation of the dorsal lateral geniculate nucleu

188 We used electrical microstimulation of the dPul while monkeys performed sac

189 Subthreshold microstimulation of the FEF enhances the responses of ar

190 over time but was transiently restored after microstimulation of the FEF.

191 embled that evoked by subsaccadic electrical microstimulation of the FEF.

192 e interrupted motion viewing with electrical microstimulation of the frontal eye field and analysed t

193 terrupted decision formation with electrical microstimulation of the frontal eye field, causing an ev

194 voluntary saccades were evoked by electrical microstimulation of the frontal eye field.

195 irection of saccades evoked by intracortical microstimulation of the frontal eye fields at variable t

196 Consistent with this idea, microstimulation of the frontal eye fields, one of sever

197 roduced by voluntary attention as well as by microstimulation of the frontal eye fields.

198 Microstimulation of the granule cell layer of both trans

199 ls and multiunit neuronal activity evoked by microstimulation of the inferior olive in Postnatal Day

200 Pupil size increased transiently after microstimulation of the intermediate SC layers (SCi) and

201 on a computer screen (optically) or through microstimulation of the lateral geniculate nucleus (elec

202 Moore described how subthreshold electrical microstimulation of the macaque frontal eye fields (FEF)

203 qualitatively similar to that evoked by weak microstimulation of the midbrain superior colliculus.

204 euron, present provocative data showing that microstimulation of the precentral cortex evokes complex

205 Single stimulus intracortical microstimulation of the primary motor cortex (M1) in awa

206 Here, we show that low-level electrical microstimulation of the primate frontal eye fields (FEFs

207 We show that microstimulation of the rhesus macaque FEF alters the ma

208 Graded electrical microstimulation of the RVM at different postnatal ages

209 n and anal sphincter contractions induced by microstimulation of the S2 spinal cord were investigated

210 to evoke colon contraction and defecation by microstimulation of the S2 spinal cord with multiple mic

211 and urethral pressures evoked by intraspinal microstimulation of the sacral segments (S1-S2) in neuro

212 ts using electrical and N-methyl-D-aspartate microstimulation of the spinal cord gray matter and cuta

213 In contrast, microstimulation of the superficial SC layers did not ca

214 Systematic mapping by electrical microstimulation of the thalamus and subthalamus reveale

215 Microstimulation of this cluster caused an increase in t

216 armacological inactivation and/or electrical microstimulation of various sites afferent and efferent

217 In this study, electrical microstimulation of VIP, but not of surrounding tissue,

218 We examined the effects of the microstimulation on smooth pursuit and on the compensati

219 devices and to further study the effects of microstimulation on the cortex, we stimulated and record

220 stimulation and was reliable within 40 ms of microstimulation onset, indicating a direct influence of

221 se properties, for example, by intracortical microstimulation or by classical conditioning paradigms.

222 nveyed to the brain through the interplay of microstimulation patterns delivered to multiple electrod

223 lerating, accelerating, and randomly varying microstimulation patterns on the likelihood and metrics

224 Surprisingly, when identical microstimulation patterns were delivered during an unrel

225 The monkeys learned to discriminate microstimulation patterns, and their ability to learn ne

226 Microstimulation produced predictable visual percepts, s

227 We applied a simple neuroprosthetic microstimulation protocol to a pair of electrodes in the

228 dings of this study suggest that even simple microstimulation protocols can be used to increase somat

229 be beneficial for this purpose, appropriate microstimulation protocols have not been developed.

230 Our results demonstrate that the pattern of microstimulation pulses strongly influences the probabil

231 Microstimulation quickened decisions in favor of the pre

232 kes with temporally and spatially structured microstimulation reliably altered the response patterns

233 ct set of afferent and efferent connections, microstimulation responses, and lesion outcomes.

234 Furthermore, electrical microstimulation resulted in highly unnatural spatial ac

235 Further, microstimulation rotates the angular preference of VPM n

236 Without microstimulation, saccades to a moving grating are biase

237 tially unfamiliar multichannel intracortical microstimulation signal, which provided continuous infor

238 Electrical microstimulation significantly biased monkeys' heading p

239 location in space as that represented at the microstimulation site in the AGF.

240 We found that microstimulation sparsely activates neurons around the e

241 We found that microstimulation strongly distorted face percepts and th

242 Microstimulation studies showed that individual force fi

243 to both whisker deflection and intracortical microstimulation, suggesting that the infrared represent

244 At the same time, AGF microstimulation suppressed the responsiveness of OT neu

245 Microstimulation systematically biased monkeys' choices

246 Electrical microstimulation targeted at LGN konio layers revealed t

247 episodic memory in humans, we implemented a microstimulation technique that allowed delivery of low-

248 Intracortical microstimulation techniques (ICMS) guided the injection

249 Intracortical microstimulation techniques (ICMS) were used in four exp

250 We use both single-unit recording and microstimulation techniques in monkey to answer this que

251 ed paired-pulse protocols with intracortical microstimulation techniques in sedated female cebus monk

252 within M1, we used long-train intracortical microstimulation techniques to evoke movements from the

253 ic (EMG) activity is a form of intracortical microstimulation that enables documentation in awake ani

254 We further demonstrate by microstimulation that LPP is connected with extrastriate

255 ectrode at microampere thresholds (threshold microstimulation; TMIS) in the region of the human thala

256 macaque frontal eye field and use electrical microstimulation to assess whether optical perturbation

257 ll-type-specific optogenetics and electrical microstimulation to characterize the koniocellular genic

258 anism physiologically by applying electrical microstimulation to columns of directionally selective n

259 lts support potential future applications of microstimulation to correct maladaptive plasticity under

260 questions, we combined fMRI with electrical microstimulation to determine the effective connectivity

261 We used microstimulation to directly activate pairs of sites in

262 otor cortex was explored using intracortical microstimulation to evoke forelimb movements.

263 as identified using repetitive intracortical microstimulation to evoke movements.

264 a combination of single-cell recordings and microstimulation to explore the organization of its topo

265 We used physiological microstimulation to identify pulvinar neurons belonging

266 We used intracortical microstimulation to map motor cortex in two NTX groups:

267 We used adaptive optics microstimulation to measure psychophysical detection thr

268 Here we applied electrical microstimulation to motor cortical areas of rhesus macaq

269 of self-motion direction, we used electrical microstimulation to perturb activity in VIP while animal

270 ly, increased attention has focused on using microstimulation to restore functions as diverse as soma

271 We also discuss potential applications of microstimulation to studies of higher cognitive function

272 We used half-second trains of intracortical microstimulation to study the functional organization of

273 We applied subthreshold microstimulation to the SC while monkeys performed a tas

274 eir gaze fixed, we delivered weak electrical microstimulation to the SC, so that saccadic eye movemen

275 The behavioural effects of microstimulation varied strikingly according to the timi

276 atients performed a person recognition task, microstimulation was applied in a theta-burst pattern, s

277 After recordings, microstimulation was applied to compare sensory and moto

278 Electrical microstimulation was applied to the motor cortex using a

279 The modulation of choice behavior using microstimulation was best modeled as resulting from chan

280 Learning effects were observed when microstimulation was delivered during the initiation of

281 Microstimulation was less effective in shifting perceptu

282 peroneal close to the ankle, and intraneural microstimulation was used to identify an area of skin in

283 Intracortical microstimulation was used to identify injection sites an

284 Intracortical microstimulation was used to investigate the organizatio

285 Electrical microstimulation was used to map bilaterally the motor c

286 Electrical microstimulation was used to study primary motor and pre

287 ostsynaptic potentials evoked by intrabulbar microstimulation, was modulated by respiration.

288 Using microstimulation we employed an explicit experimental co

289 Using intracortical microstimulation, we determined whether the supplementar

290 with multi-electrode recording and cortical microstimulation, we probed pACC function as monkeys per

291 could improve the monkey's performance with microstimulation when, but only when, the object to be a

292 By contrast, electrical microstimulation, which allows the experimenter to manip

293 es toward the stimulated RF were faster with microstimulation, while choices in the opposite directio

294 in respiratory control, we combined chemical microstimulation with both anterograde and retrograde ax

295 detect activation of their FEF by electrical microstimulation with currents below those that cause ey

296 By combining adaptive optics microstimulation with high-speed eye tracking, we show t

297 (PPC) in galagos identified by intracortical microstimulation with long stimulus trains ( approximate

298 These results suggest that microstimulation with physiologic level currents-a radic

299 Thus, microstimulation within separate zones of cortex elicite

300 Here, we used microstimulation within the motor cortex of freely behav