ライフサイエンスコーパス: microtubule-organizing center

1 retrograde transport on microtubules to the microtubule organizing center.

2 ules, which appeared to concentrate over the microtubule organizing center.

3 aberrant accumulation of mitochondria at the microtubule organizing center.

4 mplex is associated with microtubules at the microtubule organizing center.

5 it appeared to lie in close proximity to the microtubule organizing center.

6 ear envelope adopts the function as cellular microtubule organizing center.

7 tic concentration of CV membranes around the microtubule-organizing center.

8 at moves cargo on microtubules away from the microtubule-organizing center.

9 olarity is the centrosome, also known as the microtubule-organizing center.

10 ts from a globular structure adjacent to the microtubule-organizing center.

11 ed in the perinuclear region, often near the microtubule-organizing center.

12 in Saccharomyces cerevisiae functions as the microtubule-organizing center.

13 ky-inseminated eggs failed to reconstitute a microtubule-organizing center.

14 les; upon drug removal, EB1 localized to the microtubule-organizing center.

15 ordered arrays in the absence of a dedicated microtubule-organizing center.

16 are initially recruited around the polarized microtubule-organizing center.

17 ed for lysosomes to distribute away from the microtubule-organizing center.

18 associated with the trans-Golgi network and microtubule-organizing center.

19 function in the duplication of a variety of microtubule organizing centers.

20 e show that both Mbo1p and Gfh1p localize to microtubule organizing centers.

21 larity protein PAR-2 in regions distant from microtubule organizing centers.

22 sp in coordinating the nucleation of mitotic microtubule organizing centers.

23 erial, a precursor to full separation of the microtubule organizing centers.

24 r-like structures that dramatically resemble microtubule organizing centers.

25 eated mitotic cells, IAK1 is associated with microtubule organizing centers.

26 independently of either centrosomes or other microtubule organizing centers.

27 of the spindle pole bodies (SPBs), the yeast microtubule organizing centers.

28 e generation of multipolar spindles and free microtubule-organizing centers.

29 t and, in some organisms, for duplication of microtubule-organizing centers.

30 and muscle, Nin localizes to noncentrosomal microtubule-organizing centers.

31 rins are calmodulin-like proteins present in microtubule-organizing centers.

32 tubulin ring complexes localized at specific microtubule-organizing centers.

33 ytes and are rarely associated with discrete microtubule-organizing centers.

34 ge distances from the cell body and the main microtubule-organizing center?

35 ave shown that Golgi outposts serve as local microtubule-organizing centers [8] and secretory station

36 eased the number of gamma-tubulin-containing microtubule-organizing centers, a phenotype reminiscent

37 is-related abnormalities, including multiple microtubule organizing centers, aberrant mitotic spindle

38 resulted in loss of their ability to restore microtubule-organizing center activity to salt-stripped

39 nt PLK1 aggregation that led to acentrosomal microtubule-organizing center (aMTOC) formation and subs

40 n documented to reside in the centrosome, or microtubule-organizing center, an amembranous organelle

41 Third, inhibition of microtubule organizing center and centrosome polarizatio

42 ) vesicles, a recycling compartment near the microtubule organizing center and Golgi apparatus.

43 that cell spreading and polarization of the microtubule organizing center and the actin cytoskeleton

44 Consequently, the relocation of the microtubule organizing center and the Golgi apparatus in

45 aled that AIM2 inflammasomes colocalize with microtubule organizing centers and autophagosomes.

46 eral NK cells, they failed to polarize their microtubule organizing centers and perforin-containing g

47 ion of an actin ring and polarization of the microtubule-organizing center and cytolytic granules to

48 n complex constitutes a key component of the microtubule-organizing center and nucleates microtubule

49 The centrosome functions as the major microtubule-organizing center and plays a vital role in

50 Knockdown of C19ORF5 disrupts the microtubule-organizing center and results in microtubule

51 before they become competent to function as microtubule-organizing centers and basal bodies.

52 gamma-Tubulin is a conserved component of microtubule-organizing centers and is thought to be invo

53 Centrosomes are microtubule-organizing centers and play a dominant role

54 s in actin accumulation, polarization of the microtubule organizing center, and the convergence of cy

55 Polarization of talin, microtubule-organizing center, and lysosomes occurred on

56 vement of lysosome-related organelles to the microtubule-organizing center, as an early step in the c

57 localization of pM140 to an aggresome-like, microtubule organizing center-associated structure that

58 ites of microtubule overlaps associated with microtubule organizing centers at both interphase and mi

59 is how to organize a bipolar spindle without microtubule organizing centers at the poles.

60 This suppression of activation impacts microtubule organizing center-based cytoskeletal rearran

61 ctively recruited to the cap of CD20 and the microtubule organizing center became polarized toward th

62 ustered in a paranuclear region close to the microtubule organizing center, but different from the Go

63 in target cell-induced reorientation of the microtubule-organizing center, but is required for the s

64 irst travel to the centrosome (the principal microtubule organizing center) by minus-end-directed tra

65 pindle assembly occurs in the absence of the microtubule-organizing centers called centrosomes.

66 recycling endosomes concentrated around the microtubule-organizing center/centrosome.

67 Postmitotic karyoplasts assembled a microtubule-organizing center containing gamma-tubulin a

68 The accumulation of 6-PGDase at the microtubule-organizing centers could be blocked by colch

69 The reorientation of the microtubule organizing center during cell migration into

70 eation in most cells, lose their function as microtubule organizing centers during neuronal developme

71 , we show here that C19ORF5 localizes to the microtubule-organizing centers during microtubule regrow

72 Equatorial microtubule organizing center (eMTOC) activity was not a

73 TIL do not recruit granzyme B+ granules, the microtubule-organizing center, F-actin, Wiskott-Aldrich

74 -dependent translocation of the virus to the microtubule-organizing center following endosome penetra

75 tin polymerization, tubulin multimerization, microtubule organizing center formation, calcium/calmodu

76 er insight into the role of gamma-tubulin in microtubule-organizing center function.

77 ic extranuclear sites as follows: around the microtubule organizing center in association with the ci

78 Centrosomes are the major microtubule organizing center in mammalian cells and est

79 The centrosome is the major microtubule organizing center in mammalian cells.

80 The spindle pole body (SPB) is the microtubule organizing center in Saccharomyces cerevisia

81 C, and cytoskeletal filaments radiate from a microtubule organizing center in the cVAC.

82 The oocyte germinal vesicle serves as a microtubule organizing center in Xenopus oocytes; experi

83 centrosomes are major microtubule organizing centers in animal cells, and they

84 Centrosomes are the principal microtubule organizing centers in eukaryotic cells and c

85 ted for the activity of multiple acentriolar microtubule organizing centers in the oocyte.

86 Centrosomes are the major microtubule-organizing center in animal cells.

87 The centrosome is the dominant microtubule-organizing center in animal cells.

88 cycling compartment (ERC), which is near the microtubule-organizing center in many cell types.

89 female meiotic spindle lacks a centrosome or microtubule-organizing center in many organisms.

90 etected in clusters that colocalize with the microtubule-organizing center in patient cells.

91 granules move along microtubules toward the microtubule-organizing center in the minus-end direction

92 dles, but chromosomes radiated away from the microtubule-organizing centers in a prometaphase-like pa

93 Centrosomes are the main microtubule-organizing centers in animal cells.

94 Centrosomes are the main microtubule-organizing centers in animal cells.

95 lization of only a few conserved proteins at microtubule-organizing centers in animals, plants, and f

96 in control neutrophils but is found near the microtubule-organizing centers in cells from pregnant wo

97 g proteins that is an essential component of microtubule-organizing centers in many organisms ranging

98 PDase, undergoes retrograde transport to the microtubule-organizing centers in neutrophils from pregn

99 Centrin is an essential component of microtubule-organizing centers in organisms ranging from

100 ate first the positioning of the centrosome (microtubule organizing center) in the leading process in

101 mma-tubulin-containing structures (potential microtubule-organizing centers) in CACO-2 cells and demo

102 ontrolling the behavior of the fission yeast microtubule-organizing center (known as the spindle pole

103 ble microtubule arrays without a conspicuous microtubule organizing center like a centrosome.

104 flowering plants lack a structurally defined microtubule-organizing center like the centrosome, organ

105 ed peptide-MHC complexes, lytic granules and microtubule organizing center localization into synaptic

106 First, during anaphase, multiple microtubule organizing centers migrated 40 microns or mo

107 Microtubule-organizing centers move from centrosomes to

108 tubulin and microtubules but focuses to the microtubule organizing center (MTOC) after NK cell activ

109 ctin polymerization, and polarization of the microtubule organizing center (MTOC) and cytolytic granu

110 In this study, we report that, whereas the microtubule organizing center (MTOC) and cytosolic granu

111 embryos, which involve reorientation of the microtubule organizing center (MTOC) and Golgi apparatus

112 inant centrosome." This centrosome acts as a microtubule organizing center (MTOC) and remains station

113 through the movement of vesicles toward the microtubule organizing center (MTOC) and translocation o

114 intermediate chain (CDIC) colocalize at the microtubule organizing center (MTOC) around the nucleus

115 y impaired LFA1 polarization, spreading, and microtubule organizing center (MTOC) formation in NK cel

116 ciency induces significant separation of the microtubule organizing center (MTOC) from the nuclear en

117 The centrosome is the major microtubule organizing center (MTOC) in dividing cells a

118 e T cell polarization and recruitment of the microtubule organizing center (MTOC) in HIV-1-infected c

119 The spindle pole body (SPB) is the microtubule organizing center (MTOC) in the yeast Saccha

120 o the leading edge and, surprisingly, to the microtubule organizing center (MTOC) of migrating fibrob

121 abrogated, including increased calcium flux, microtubule organizing center (MTOC) polarization, phosp

122 , we assessed the location of the centrosome/microtubule organizing center (MTOC) relative to the cel

123 hat Klarsicht is required for connecting the microtubule organizing center (MTOC) to the nucleus.

124 phocytes (CTL) requires translocation of the microtubule organizing center (MTOC) to the target cell

125 ngle NK cell, signal the polarization of the microtubule organizing center (MTOC) together with cytol

126 mNudE is located in the centrosome or microtubule organizing center (MTOC), and interacts with

127 and furthermore, blocked the movement of the microtubule organizing center (MTOC), granzyme B (a comp

128 pPKCdelta(Thr505) co-localized with two key microtubule organizing center (MTOC)-associated proteins

129 gion (outside the cell nucleus) known as the microtubule organizing center (MTOC).

130 lear migration by linking the nucleus to the microtubule organizing center (MTOC).

131 the capsid moves to and associates with the microtubule organizing center (MTOC).

132 ubulin complex (gamma-TuC), and composes the microtubule organizing center (MTOC).

133 ic leukemia oncogenic domains (PODs) and the microtubule organizing center (MTOC).

134 urrounded by microtubules radiating from the microtubule organizing center (MTOC).

135 ion of T cells involves reorientation of the microtubule organizing center (MTOC).

136 rliest point, the initiation of the daughter microtubule organizing center (MTOC).

137 LIS1 is a microtubule- (MT) and centrosome- [microtubule organizing center (MTOC)] associated protein

138 whether AurA can stimulate the formation of microtubule organizing centers (MTOC) on its own.

139 ment site, as judged by reorientation of the microtubule-organizing center (MTOC) and localized actin

140 e parasitophorous vacuole (inclusion) to the microtubule-organizing center (MTOC) and promotes its fu

141 caused swift granule concentration near the microtubule-organizing center (MTOC) and subsequent deli

142 n-dependent lytic granule convergence to the microtubule-organizing center (MTOC) as an early, prereq

143 ic TIL and cognate tumor cells in vitro, the microtubule-organizing center (MTOC) does not localize t

144 The centrosome acts as the microtubule-organizing center (MTOC) during mitosis in a

145 ding pericentriolar material, is the primary microtubule-organizing center (MTOC) in animal cells.

146 The nucleus is the main microtubule-organizing center (MTOC) in muscle cells due

147 In contrast, reorientation of the T cell microtubule-organizing center (MTOC) is dependent on and

148 The microtubule-organizing center (MTOC) is reoriented betwe

149 ted motor protein, moves cargo away from the microtubule-organizing center (MTOC) on microtubules.

150 stepwise with actin reorganization preceding microtubule-organizing center (MTOC) polarization to the

151 ch as fibroblasts and endothelial cells, the microtubule-organizing center (MTOC) reorients toward th

152 by an apical complex that contains a unique microtubule-organizing center (MTOC) that organizes the

153 In T lymphocytes, polarization of the microtubule-organizing center (MTOC) to the immunologica

154 immunological synapse, translocation of the microtubule-organizing center (MTOC) to the synapse, and

155 The reorientation of the T cell microtubule-organizing center (MTOC) toward the antigen-

156 Polarization of the T cell microtubule-organizing center (MTOC) toward the antigen-

157 ical synapse as well as reorientation of the microtubule-organizing center (MTOC) toward the APC.

158 ormed by the splitting and separation of the microtubule-organizing center (MTOC) well before nuclear

159 e monitored by analyzing the position of the microtubule-organizing center (MTOC), as it moves toward

160 ns a relatively constant localization at the microtubule-organizing center (MTOC), Nuf is present at

161 FV capsid assembly takes place near the host microtubule-organizing center (MTOC).

162 zed at Golgi membranes and apparently at the microtubule-organizing center (MTOC).

163 as well as on the later polarization of the microtubule-organizing center (MTOC).

164 Moreover, the microtubule-organizing center (MTOC, or centrosome), whi

165 ly at centrosomes, but more diverse types of microtubule organizing centers (MTOCs) also exist, espec

166 Non-centrosomal microtubule organizing centers (MTOCs) direct microtubul

167 the poles of the spindle that can persist as microtubule organizing centers (MTOCs) into interphase.

168 Regulation of microtubule organizing centers (MTOCs) orchestrates the

169 niversal role in microtubule nucleation from microtubule organizing centers (MTOCs) such as the anima

170 nucleation from noncentrosomal intracellular microtubule organizing centers (MTOCs), although such st

171 entriole/kinetosomes, centrosomes, and other microtubule organizing centers (MTOCs), whether by direc

172 and associated proteins present at specific microtubule organizing centers (MTOCs).

173 on with pericentrin and gamma-tubulin within microtubule organizing centers (MTOCs).

174 hese microaggregates were not transported to microtubule organizing centers (MTOCs).

175 and was characterized by the loss of obvious microtubule organizing centers (MtOCs).

176 d microtubules extending from poorly defined microtubule organizing centers (MTOCs).

177 a duplication and separation of centrosomal microtubule organizing centers (MTOCs).

178 known centrosomal proteins with two types of microtubule organizing centers (MTOCs): (1) the central

179 mologue of MOZART1, Mzt1/Tam4, is located at microtubule-organizing centers (MTOCs) and coimmunopreci

180 the gamma-TuC becomes active specifically at microtubule-organizing centers (MTOCs) and not more broa

181 In young embryos, hundreds of microtubule-organizing centers (MTOCs) are assembled com

182 Microtubule-organizing centers (MTOCs) are large, multi-

183 shown previously that centrosomes and other microtubule-organizing centers (MTOCs) attach to the api

184 Microtubule-organizing centers (MTOCs) form, anchor, and

185 lta (CK1delta) family members associate with microtubule-organizing centers (MTOCs) from yeast to hum

186 alizes with gamma-tubulin and pericentrin at microtubule-organizing centers (MTOCs) in mouse oocytes

187 HA-tagged GTU1p localizes to four microtubule-organizing centers (MTOCs) in vegetative cel

188 Positioning of microtubule-organizing centers (MTOCs) incorporates bioc

189 Microtubule-organizing centers (MTOCs) nucleate microtub

190 In simple epithelial cells, attachment of microtubule-organizing centers (MTOCs) to intermediate f

191 rives the polarization of lytic granules and microtubule-organizing centers (MTOCs) toward the immune

192 is self-assembled from randomly distributed microtubule-organizing centers (MTOCs) without centriole

193 Microtubule-organizing centers (MTOCs), known as centros

194 yos led to the de novo formation of multiple microtubule-organizing centers (MTOCs).

195 at form the core structure of centrosomes or microtubule-organizing centers (MTOCs).

196 In many asymmetrically dividing cells, the microtubule-organizing centers (MTOCs; mammalian centros

197 ), as the cortical anchor for noncentrosomal microtubule organizing centers (ncMTOCs) in the Drosophi

198 Salmonella-containing vacuoles close to the microtubule organizing center of infected epithelial cel

199 The spindle pole body (SPB) is the microtubule organizing center of Saccharomyces cerevisia

200 The microtubule organizing center of stopped cells was posit

201 2 is a core component of the centrosome, the microtubule organizing center of the cell, and functiona

202 The centrosome is the primary microtubule organizing center of the cells and templates

203 component centrioles represent the principal microtubule organizing centers of animal cells.

204 The spindle pole body (SPB) is the major microtubule-organizing center of budding yeast and is th

205 The centrosome is the major microtubule-organizing center of most mammalian cells an

206 the majority of animals, the centrosome-the microtubule-organizing center of the cell-is assembled f

207 Centrosomes are the microtubule-organizing centers of animal cells that orga

208 trol of the number of centrosomes, the major microtubule-organizing centers of animal cells, is criti

209 organelles that build centrosomes, the major microtubule-organizing centers of animal cells.

210 It is found in microtubule-organizing centers of organisms ranging from

211 he K.VP1-2DeltaNLS mutant was blocked at the microtubule organizing center or immediately upstream of

212 at form at pericentriolar sites close to the microtubule organizing center or in specialized nuclear

213 -vesicular structures either adjacent to the microtubule-organizing center or widely distributed in t

214 uf1p) is an essential component of the yeast microtubule organizing center, or spindle pole body (SPB

215 mmon localization of the two proteins in the microtubule organizing center, our results suggest that

216 me, an organelle that functions as the major microtubule-organizing center, plays an essential role i

217 Surprisingly, microtubule organizing center polarity at the IS, which

218 ensable for thymocyte development as well as microtubule organizing center polarization and cytolytic

219 Microtubule organizing center polarization and granule r

220 ion over this range significantly suppressed microtubule organizing center polarization and granzyme

221 lytic granule secretion and by showing that microtubule organizing center polarization is dispensabl

222 zation at the contact site with APC, altered microtubule-organizing center polarization and the IS st

223 d is required for conjugate formation, MTOC (microtubule organizing center) polarization, and NKG2D-d

224 etheless, naive CD8(+) T cells polarized the microtubule organizing center, produced IL-2, proliferat

225 dle is formed through the action of multiple microtubule organizing centers rather than a pair of cen

226 m store release and diacylglycerol-dependent microtubule organizing center reorientation, while deple

227 transiently at the T cell/APC interface, the microtubule organizing center reoriented toward it.

228 The basal body is a microtubule-organizing center responsible for organizing

229 complexes that mediate chromosome movement (microtubule organizing centers, spindles, and kinetochor

230 or reasons still speculative, lack the major microtubule organizing centers that most cells use to as

231 Centrosomes are key microtubule-organizing centers that contain a pair of ce

232 Centrosomes are microtubule-organizing centers that facilitate bipolar m

233 mal structures-distinct from elements of the microtubule-organizing center-that is required for the s

234 duplication of the Saccharomyces cerevisiae microtubule organizing center, the spindle pole body (SP

235 formation is based on the action of multiple microtubule organizing centers, the chromosomes not only

236 Despite the importance of centrosomes as microtubule-organizing centers, the mechanism and regula

237 animal cells states that centrosomes act as microtubule-organizing centers throughout the cell cycle

238 rved role in fenestration to enable a single microtubule organizing center to nucleate both cytoplasm

239 l polarity was indicated by a failure of the microtubule-organizing center to align with the directio

240 h microtubules emanating from the equatorial microtubule-organizing center to position the nuclei awa

241 e that C19ORF5 plays a role in anchoring the microtubule-organizing center to the centrosomes.

242 cell targets and induce reorientation of the microtubule-organizing center to the immunologic synapse

243 raffic determined by the polarization of the microtubule-organizing center to the immunological synap

244 ation of CTLA-4 and the reorientation of the microtubule-organizing center to the site of T-cell rece

245 These infected cells did not begin to lose microtubule-organizing centers until 13 hpi.

246 i.e., AURKA, PLK1, and gamma-tubulin) to the microtubule-organizing center via the RhoA signaling pat

247 it is shown that a marker protein for plant microtubule organizing centers, which has been shown to

248 case of an unsuccessful polarization of the microtubule-organizing center, which alters the polarity

249 icrotubules is determined in most cells by a microtubule-organizing center, which nucleates microtubu

250 ed by AK301 showed the formation of multiple microtubule organizing centers with Aurora kinase A and

251 ctors and the posterior establishment of the microtubule organizing center within the presumptive ooc

252 s served as a model system for understanding microtubule organizing centers, yet very little is known