ライフサイエンスコーパス: microvascular density

1 in-8 (IL-8) on tumor growth and intratumoral microvascular density.

2 reased VEGF and FGF2 BM plasma levels and BM microvascular density.

3 ced distant tumor growth, proliferation, and microvascular density.

4 ed seizures also caused robust reductions in microvascular density.

5 ch was confirmed by histological analysis of microvascular density.

6 rowth, proliferation (Ki-67 percentage), and microvascular density.

7 t angiogenic factor, VEGF; and (3) decreased microvascular density.

8 CBF is correlated with tumor microvascular density.

9 proteinase-9 in GFAP-positive astrocytes and microvascular density.

10 with contractile function (wall motion) and microvascular density.

11 e to insulin, exercise and VEGF-A and reduce microvascular density.

12 ly accompanied by an increase in dental pulp microvascular density.

13 h histopathologic findings for viability and microvascular density.

14 ted for Ki-67 proliferative indexes and CD34 microvascular density.

15 intraepithelial COX-2 and iNOS proteins, and microvascular densities.

16 Likewise, microvascular density, a histologic surrogate of angioge

17 The LVAD unloading resulted in increased microvascular density accompanied by increased fibrosis

18 as-induced murine colon carcinomas increased microvascular densities and vessel sizes.

19 ings were associated with both reduced tumor microvascular density and a reduction in the amount of v

20 alysis also showed significant reductions in microvascular density and actively dividing cells in the

21 tumors and caused a significant reduction in microvascular density and alphavbeta3 integrin expressio

22 ontrast-enhanced intensity corresponded with microvascular density and blood volume.

23 red, resulting in smaller tumors and reduced microvascular density and branching.

24 each patient was compared with the ratio of microvascular density and capillary area (r=0.84 and 0.8

25 s was associated with increased intratumoral microvascular density and enhanced endothelial cell surv

26 SIT and ET are effective in improving muscle microvascular density and eNOS protein content.

27 ed intestines of CRHR1(-/-) mice had reduced microvascular density and expression of vascular endothe

28 sults in lethality attributable to decreased microvascular density and hemorrhages.

29 wth inhibition was associated with decreased microvascular density and increased vascular leakage.

30 MCF7-MCT-1 tumors in vivo, we found greater microvascular density and lower apoptosis in the MCF7-MC

31 /- mice had significantly increased cerebral microvascular density and more effective restoration of

32 NTR1-knockout mice had reduced microvascular density and mucosal integrity score compar

33 lar hypertension, normalized stenotic kidney microvascular density and oxygenation, stabilized functi

34 No differences in microvascular density and sympathetic or pan-neuronal in

35 dentified recovery of function compared with microvascular density and the sole use of peak MCI.

36 try and histomorphometry of the BM to assess microvascular density and to evaluate pan-neuronal and s

37 n nonmetastatic mammary tumor cells elevated microvascular density and vascular recruitment.

38 ile a physically active lifestyle keeps both microvascular density and vasodilator response high.

39 gnificant correlations were observed between microvascular density and vessel perimeter and area (r =

40 42, von Willebrand factor (VWF; a measure of microvascular density) and the potent vasoconstrictor en

41 n is associated with increased inflammation, microvascular density, and blood clotting.

42 decreased tumor volume, tumor cell survival, microvascular density, and lung metastasis relative to t

43 therapy also decreased BP and improved GFR, microvascular density, and oxygenation in the stenotic k

44 had reduced cutaneous hair-follicle density, microvascular density, and panniculus adiposus layer thi

45 st area, liver/body weight ratio, pericystic microvascular density, and PCNA expression while increas

46 unostaining indicated decreased intratumoral microvascular density, and TUNEL demonstrated enhanced t

47 overexpression increased tumor VEGF levels, microvascular density, and vessel permeability, whereas

48 pth, proliferation, macrophage infiltration, microvascular density, apoptosis) were assessed after a

49 Increases in the tumor microvascular density are accompanied by a strong reduct

50 Two weeks after implantation, microvascular density, as measured by capillaries per hi

51 ted growth of BT474 xenografts and decreased microvascular density associated with downregulation of

52 no significant differences were observed in microvascular density between young and aged mice in nor

53 16K) cells was correlated with a decrease in microvascular density by 44%.

54 ls were disorganized and displayed decreased microvascular density by embryonic day 11.5.

55 We can, therefore, conclude that brain microvascular density can be controlled by HIF-independe

56 anied by a significant reduction in the mean microvascular density compared to the IgG control group.

57 ease distant tumor growth, proliferation, or microvascular density compared with sham treatment.

58 angiogenic gene signatures and had a higher microvascular density compared with their SOX11-negative

59 c (716/+) mice had significant reductions in microvascular density, consistent with the high expressi

60 r, EGFR and HER2/neu overexpression and high microvascular density correlate with survival.

61 ciated endothelial cell apoptosis, decreased microvascular density, decreased proliferation rate, and

62 Reduced microvascular density diminished the ability of the brai

63 uantifying changes in the marrow vascular by microvascular density, do not differentiate between diff

64 Clinical observations of increased colon microvascular density during IBD have been made.

65 ld, endocardium-to-epicardium evaluation for microvascular density, fibrosis, cardiomyocyte size, and

66 tyle keeps both the vasodilator response and microvascular density high.

67 production retained significantly increased microvascular density, improved glucose profiles, and in

68 GF signaling does not result in reduction of microvascular density in a variety of tumor models.

69 fibrin deposits (5) significantly increased microvascular density in lumbar spinal cord, (6) IgG mic

70 There was a significant reduction in microvascular density in patients with CHF compared with

71 revealed a significant increase in hindlimb microvascular density in response to experimentally indu

72 herapy reduced both the total and functional microvascular density in the brain xenografts.

73 icate some established breast tumors, reduce microvascular density in the remaining tumors, protect a

74 site for breast cancer progression, and high microvascular density in tumors is a poor prognostic ind

75 uced endothelial cell migration in vitro and microvascular density in vivo.

76 decreases tumor perfusion, vascular volume, microvascular density, interstitial fluid pressure and t

77 Importantly, microvascular density is significantly less, correlating

78 ll lung cancer (NSCLC) tumors have increased microvascular density, localized hypoxia, and high VEGF

79 Myocardial microvascular density (MCD) in aFGF-NP+UTMD group was up

80 performed to compare groups 1 and 2 both for microvascular densities (MVD) on histologic sections and

81 Microvascular density (MVD) and percentage of microvascu

82 planted into Cav-2 KO mice displayed reduced microvascular density (MVD) determined by IHC with anti-

83 relation 0.610, P = 0.0033) and pretreatment microvascular density (MVD) in all patients (Spearman co

84 was performed through the imaged tissue, and microvascular density (MVD) was determined, together wit

85 rast medium between K(PS) and the histologic microvascular density (MVD), an angiogenesis indicator.

86 sets (i.e., radiomic imaging features, tumor microvascular density (MVD), and vascular endothelial gr

87 in full-thickness left ventricular sections, microvascular density (MVD), myocardial fibrosis, and th

88 helial markers that can be used to calculate microvascular density (MVD).

89 gher RPS15A expression demonstrated a higher microvascular density (MVD).

90 ib alone were stained with CD31 to determine microvascular density (MVD).

91 Neither reduced functional microvascular density nor major alterations in arterial

92 l CT sections were examined to measure tumor microvascular density, number of luminal vessels, vascul

93 The microvascular density of bone marrow did not change sign

94 n the CHF group suggests that a reduction in microvascular density of skeletal muscle may precede oth

95 tudy changes in the marrow vasculature using microvascular density or quantifying changes in the vasc

96 of distant tumor growth, proliferation, and microvascular density (P < .01).

97 This was accompanied by a 33% increase in microvascular density (p = 0.001) and a 36% decrease in

98 inent feature of TSP2-null mice is increased microvascular density, particularly in connective tissue

99 dihydrotetrabenazine, insulin staining, and microvascular density patterns were consistent with isle

100 Microvascular density (percentage of vessel area divided

101 ein, acidic, and rich in cysteine) < 5%, and microvascular density quartile 4.

102 CBF was strongly correlated with microvascular density (R = 0.66, P < .001).

103 Peak MCI correlated with microvascular density (r=0.59, P<0.001) and capillary ar

104 ronary collaterals correlated with increased microvascular density, reduced fibrosis, and decreased l

105 Afferent microvascular density +/- standard deviation in LA lesio

106 LA microvascular density tended to be lower in HFpEF and in

107 of (68)Ga-NODAGA-c(RGDfK) was correlated to microvascular density, vascular morphology, and permeabi

108 not affect the vascular parameters including microvascular density, vascular size, and vascular archi

109 The correlation between CBF and microvascular density was analyzed in specimens stained

110 Microvascular density was compared between control (n=6)

111 eated eyes by image processing software, and microvascular density was determined by counting von Wil

112 Likewise, distant tumor microvascular density was greater for 5-W MWA and RFA (P

113 Microvascular density was reduced significantly in CLI c

114 A significant overlap in microvascular density was seen between segments with and

115 Microvascular density was significantly diminished by th

116 Mean tumor microvascular density was significantly lower in SU5416-

117 The microvascular density was significantly reduced in the x

118 epithelial COX-2 and iNOS protein levels and microvascular densities were determined by image analysi

119 cells demonstrated that mast cell number and microvascular density were significantly higher in S-P t

120 endothelial cell apoptosis and reduction of microvascular density within the core of the tumor leadi

121 lls, mononuclear cells), blood clotting, and microvascular density within the tumors produced by subc