ライフサイエンスコーパス: microvasculature

1 (cancer, healthy mucosa, smooth muscle, and microvasculature).

2 eing physiological functions of the cerebral microvasculature.

3 sional architecture and flow patterns of the microvasculature.

4 eased nodal density, and decreased pulmonary microvasculature.

5 erapeutic strategies targeting the pulmonary microvasculature.

6 thrombi in the high sheer environment of the microvasculature.

7 odeling are linked to dynamic changes in the microvasculature.

8 ercussions of SCA on skeletal muscle and its microvasculature.

9 mation of freestanding luminal multicellular microvasculature.

10 nd function of newly formed tumor stroma and microvasculature.

11 ts the cell's ability to transport oxygen in microvasculature.

12 s with growth and refinement of the cerebral microvasculature.

13 ginates from the involvement of the coronary microvasculature.

14 unoreactivity were often associated with the microvasculature.

15 -Tg mice show a morphologically disorganized microvasculature.

16 ylcholine-mediated vasodilation in the renal microvasculature.

17 CD31 and CD34 revealed a sparse microvasculature.

18 the red blood cell's ability to sequester in microvasculature.

19 f 20-HETE to myogenic tone in the mesenteric microvasculature.

20 s in endothelial cells (EC) of the allograft microvasculature.

21 infected erythrocytes (IEs) to the cerebral microvasculature.

22 resent an adaptation to the CTH of the local microvasculature.

23 re particularly well suited for modeling the microvasculature.

24 gene expression and stabilize the pulmonary microvasculature.

25 on resulted in profound changes to the tumor microvasculature.

26 with parasite sequestration in the cerebral microvasculature.

27 d (iii) CD8(+) T cell arrest in the cerebral microvasculature.

28 ls and selectin-expressing host cells in the microvasculature.

29 e cells are integral components of the brain microvasculature.

30 ted to enhanced permeability of the synovial microvasculature.

31 ogenesis and their role in regulation of the microvasculature.

32 r dysfunction in the dn-CREB-expressing lung microvasculature.

33 frequency inhomogeneity and displaced normal microvasculature.

34 murine PDA, normalize IFP, and re-expand the microvasculature.

35 o endothelial cells, thereby obstructing the microvasculature.

36 thogenic variants, mainly affects the kidney microvasculature.

37 icantly altered leukocyte recruitment to the microvasculature.

38 phA2 and A4, overexpressed in the pancreatic microvasculature.

39 ons of platelets with other cells within the microvasculature.

40 (BH(4)) has not been studied in the cerebral microvasculature.

41 ost efficient in this portion of the retinal microvasculature.

42 iprocally regulate basal perfusion of muscle microvasculature.

43 formly partition red blood cells through the microvasculature.

44 for improving NOS coupling mechanisms in the microvasculature.

45 chemia induced by a transient loss of airway microvasculature.

46 ssary to survive the shear forces within the microvasculature.

47 ascular dysfunction evident in the cutaneous microvasculature.

48 ve microperfusion data from gated human foot microvasculature.

49 a course and its relation to the normal iris microvasculature.

50 ical changes in the cellular elements of the microvasculature.

51 d delivery and tethering of TLN in the organ microvasculature.

52 s undergo interactions within the glomerular microvasculature.

53 a progressive lung disease of the pulmonary microvasculature.

54 ervable surrogate for the neural or systemic microvasculature.

55 and inhibited the reactivity of the cerebral microvasculature.

56 ostatic factors needed to produce functional microvasculature.

57 t the structure and function of human kidney microvasculature.

58 t the loss of plasma-borne proteins from the microvasculature.

59 inical assessment of major blood vessels and microvasculature.

60 d delivery and tethering of TLN in the organ microvasculature.

61 to IL-1beta-induced activation of the brain microvasculature.

62 factors influencing the size of the retinal microvasculature.

63 because of its ability to cytoadhere in the microvasculature.

64 y (18)F-FDG imaging, but also in peritumoral microvasculature.

65 ascular wall in large vessels and within the microvasculature.

66 ate normal and retarded transit scenarios in microvasculature.

67 CSE and 3-MST are expressed in the human microvasculature.

68 es and erythrocytes sickle and adhere in the microvasculature, a process dependent on the concentrati

69 regression of the peritubular and glomerular microvasculature, accompanied by tubulointerstitial dama

70 tion of monocytes marginated within the lung microvasculature, achieved by pretreating mice with i.v.

71 hypertensive disorders during pregnancy with microvasculature adaptations in the offspring in childho

72 ring pregnancy is associated with persistent microvasculature adaptations in their children.

73 d that aggregates are present throughout the microvasculature, affecting cell distribution and blood

74 cular endothelial cell cultures and cerebral microvasculature after ischaemic stimuli.

75 xhibited a steady ingrowth of blood-perfused microvasculature along with an increase in amplitude of

76 ents, which are characterized by dense leaky microvasculature and acidic extracellular pH (pHe ) valu

77 The pulmonary microvasculature and alveoli in the intact animal were i

78 n glucose nevertheless restores the cerebral microvasculature and ameliorates disease.

79 to survive in vivo by sequestering IE in the microvasculature and avoiding splenic clearance mechanis

80 Brain microvasculature and glial cells respond in concert to i

81 We examined the effect of GLP-1 on muscle microvasculature and glucose uptake.

82 Special attention is given to the microvasculature and hepatic mononuclear phagocytic syst

83 In conclusion, GLP-1 acutely recruits microvasculature and increases basal glucose uptake in m

84 res of native in vivo human dermal lymphatic microvasculature and is stable over many weeks.

85 ach, including direct visualization of renal microvasculature and measurement of oxygen kinetics and

86 ronary atherosclerosis and centers it on the microvasculature and myocardial cell where the ischemia

87 latelet dependent, NETs appeared in the lung microvasculature and NET components increased in the pla

88 ing visualization of major blood vessels and microvasculature and providing images of hemoglobin oxyg

89 The mechanisms underlying repair of the microvasculature and recovery of kidney function are poo

90 latory protein was demonstrated in the brain microvasculature and the activity of this protein is dec

91 mes likely mediated by interactions with the microvasculature and the cardiomyocyte.

92 retention were mainly dictated by the tumor microvasculature and the enhanced permeability and reten

93 effects of HIV-1 infection on the pulmonary microvasculature and the modulatory effects of the PPAR-

94 rtension, defined by reduction of the distal microvasculature and the presence of numerous dilated ar

95 delivered through the blood vessels of tumor microvasculature and the response to treatment is studie

96 enabling them to adhere to receptors in the microvasculature and thereby avoid clearance by the sple

97 Insulin resistance is present in muscle microvasculature and this may contribute to decreased in

98 brovascular system and gray matter, altering microvasculature and tissue structure.

99 stochemistry localised MCT8 and MCT10 to the microvasculature and to undifferentiated CNS cells.

100 critical for the development of a functional microvasculature and vascular remodeling.

101 associated with deterioration of the kidney microvasculature and/or the reenactment of embryonic pat

102 tion, suggesting that Notch functions in the microvasculature and/or veins to induce AVM.

103 otassium signaling from the astrocyte to the microvasculature, and astrocytic mechanosensation of vas

104 ence of activated leukocytes in the cerebral microvasculature, and blood-brain barrier leakage, indic

105 g injury (VILI), NETs were found in the lung microvasculature, and circulating NET components increas

106 lso displayed increased net neurogenesis and microvasculature, and diminished astrocyte hypertrophy a

107 al image contrast was adjusted to isolate AH microvasculature, and images were viewed in a 3D viewer.

108 e-endothelial cell interactions in the brain microvasculature, and increased inflammation in brain (i

109 that insulin enters endothelial cells of the microvasculature, and studies with large vessel-derived

110 validated K(trans) as an indicator of plaque microvasculature, and the reproducibility of K(trans) wa

111 ctins constitutively expressed by the marrow microvasculature, and thus for marrow homing, we conduct

112 ause spatial and temporal data suggested the microvasculature as a common site of origin for these ce

113 ce results in defects in retinal and cardiac microvasculature as well as heart development.

114 D8(+) T cells, and neutrophils in the dermal microvasculature, as well as increased T cell expression

115 The microvasculature assumes an inflammatory and procoagulan

116 Greatly waned neurogenesis, diminished microvasculature, astrocyte hypertrophy and activated mi

117 CTA yields images of the normal and diseased microvasculature at all levels of the retina, with highe

118 emerging as a powerful technique for imaging microvasculature at depths beyond the ~1 mm depth limit

119 iving subjects, including detection of tumor microvasculature at twice the depth achievable with conv

120 Obstruction of the brain microvasculature because of sequestration of parasitized

121 ional and structural alterations in cerebral microvasculature before and after experimental cerebral

122 and the fact that it is not specific for the microvasculature but interrogates the entire coronary ci

123 rived pericytes populate the entire coronary microvasculature, but differentiate into caSMCs at arter

124 ) will cause occlusion if they sickle in the microvasculature, but have minimal (or no) consequences

125 Half a century ago, detailed studies of the microvasculature by electron microscopy revealed that un

126 ffective dose significantly recruited muscle microvasculature by increasing muscle microvascular bloo

127 suggest that a) morphological changes in the microvasculature can be measured noninvasively using MRI

128 link between disease progression and hepatic microvasculature changes can be made.

129 eling - cardiomyocyte hypertrophy, fibrosis, microvasculature changes, adrenergic pathways and sympat

130 This microvasculature coexisted with endothelial cell-associa

131 chymal cells, suggesting that the intestinal microvasculature contributes to IBD-associated fibrosis

132 pendent of ICAM-1 expression on the cerebral microvasculature, contributes to ECM.

133 p formation, and thrombosis in the pulmonary microvasculature culminated in right ventricular dysfunc

134 CL10, was significantly upregulated, whereas microvasculature CXCL12 expression was significantly dec

135 diated repletion of the protein averts brain microvasculature defects and prevents disease, whereas a

136 reater MBF was accompanied by an increase of microvasculature density in the infarcted region (P=0.01

137 s unit is functional hyperemia, in which the microvasculature dilates in response to local neural act

138 lt to find consistent changes in the retinal microvasculature due to large intersubject variability.

139 Here, we evaluated the coronary and renal microvasculature during CRMS development in obese diabet

140 ever, imaging this organ and its complicated microvasculature during different forms of renal patholo

141 ostatic perfusion pressures in the pulmonary microvasculature during systemic inflammation.

142 or neuroscience research and for visualizing microvasculature dynamics involved in tumor angiogenesis

143 e mechanism(s) of iron flux across the brain microvasculature endothelial cells (BMVEC) of the blood-

144 otes CXCR4-mediated T cell adhesion to brain microvasculature endothelial cells.

145 roperties and markers expanded radially from microvasculature explants.

146 asate when the CNS is inflamed and the brain microvasculature expresses high levels of integrin ligan

147 To assess the morphology of brain microvasculature far more rigorously than what is possib

148 murine bone marrow (BM) and skeletal-muscle microvasculature fluctuated with circadian peak values a

149 advancement toward the development of human microvasculature for basic and translational studies.

150 We propose the concept of reactive microvasculature for the evolution of reactive stroma at

151 etical analyses revealed that the subsurface microvasculature formed interconnected loops with a topo

152 site of origin for these cells, we analyzed microvasculature fragments in organ culture.

153 on of VEGFA in diabetic kidneys protects the microvasculature from injury and that reduction of VEGFA

154 dria with partial cristolysis in the retinal microvasculature from PC rats, compared with those from

155 and ECs must be considered in evaluation of microvasculature function in acute inflammation.

156 en level-dependent measurements that reflect microvasculature function.

157 es the unique ability to study metabolic and microvasculature functions in skeletal muscle using phos

158 Ferumoxsil opacified the coronary microvasculature (group 2) on MR-matched histologic sect

159 Sub-millimeter visualization of microvasculature has facilitated the detection of microb

160 MICT), but its effect on the skeletal muscle microvasculature has not been studied in obese individua

161 ial fibrosis, enhanced preservation of renal microvasculature, improvement in renal blood flow, and l

162 intrinsic self-assembly capability to create microvasculature in a deliverable matrix, has vast ramif

163 constituted a three-dimensional human kidney microvasculature in a flow-directed microphysiologic sys

164 urea has immediate beneficial effects on the microvasculature in acute sickle-cell crises that are in

165 erence standard for invasively assessing the microvasculature in clinical trials.

166 preciation of the importance of the coronary microvasculature in determining patient outcomes has gro

167 pregulation of VEGFA protects the glomerular microvasculature in diabetes and that therefore inhibiti

168 o establish an essential role of the hepatic microvasculature in embryonic hematopoiesis.

169 GF-CC neutralization had no effects on renal microvasculature in healthy animals.

170 the role and mechanism of HHcy-induced ED in microvasculature in our newly established mouse model of

171 g modality to quantify the retinal capillary microvasculature in patients with diabetes.

172 Microvasculature in peri-infarct area, infarct size, and

173 body could efficiently target human synovial microvasculature in SCID mice transplanted with human ar

174 provided detailed imaging of the perifoveal microvasculature in sickle cell disease.

175 re found to adhere more readily to the brain microvasculature in Tat treated animals.

176 ions of Borg5, septin, and actomyosin in the microvasculature in the context of development and disea

177 se in transferrin receptor expression in the microvasculature in the presence of relative brain iron

178 nable visualization of fluorescent cells and microvasculature in various mouse organs.

179 remodelling and barrier function in retinal microvasculature in vitro and in vivo.

180 To estimate the density of the cortical microvasculature in vivo, we used contrast-enhanced magn

181 e generation of new myocardium (myocytes and microvasculature) in infarcted and peri-infarct/border r

182 ic control and subsequent changes in retinal microvasculature, in a pilot study of 55 pediatric T1D p

183 hysiologically and morphologically realistic microvasculature including endothelial cell lined leaky

184 d with vascular dysfunction in the cutaneous microvasculature, induced in part by upregulated arginas

185 -1.2 per year), tubulitis (1.5, 1.3-1.8) and microvasculature injury (2.9, 1.4-5.7).

186 nclusion, pediatric RTR with de novo DSA and microvasculature injury were at risk of allograft failur

187 ascular remodeling of the hepatic sinusoidal microvasculature, intussusceptive angiogenesis, and dysr

188 er cell migration/invasion toward angiogenic microvasculature is a key step in metastatic spread.

189 D, but what causes them and why the cerebral microvasculature is affected have never been adequately

190 endothelial cells (ECs) and pericytes in the microvasculature is fundamental for vascular growth and

191 The microvasculature is important for vertebrate organ devel

192 Transport of insulin across the microvasculature is necessary to reach its target organs

193 It has become evident that the exchange microvasculature is not simply a passive biophysical bar

194 However, the retinal microvasculature is not simply a well-coupled syncytium

195 the electrotonic architecture of the retinal microvasculature is not static, but rather, is dynamical

196 ommunicate through a cell-poor zone with the microvasculature is observed.

197 These results indicate that the cerebral microvasculature is rendered vulnerable to thrombus form

198 During inflammation, whereas the microvasculature is responsible for the entry and distri

199 on molecule 1 (ICAM-1) upregulation in brain microvasculature is the only one correlated to cerebral

200 s angiogenesis, but the effect on the kidney microvasculature is unknown.

201 B (ETB) receptors, overexpressed in the lung microvasculature, is associated with accumulation of pro

202 igen mediating parasite sequestration in the microvasculature, is encoded in parasites by a highly di

203 flow pulsatility into the susceptible renal microvasculature, leading to dynamic constriction or ves

204 uitment and activation within the glomerular microvasculature, leading to neutrophil-dependent tissue

205 imately control - human cell behavior at the microvasculature level.

206 nd function resulting in obliteration of the microvasculature.Lytic EC injury: Lethal exposure to DSA

207 work suggests that inadequacy of the cardiac microvasculature may be the primary abnormality and has

208 d physiological deformation of the pulmonary microvasculature may exacerbate vascular injury during R

209 low pulsatility into the low-impedance renal microvasculature may mediate this association.

210 t an in vitro "endothelialized" microfluidic microvasculature model that recapitulates and integrates

211 sing sRBC adhesion in our microfluidic human microvasculature models.

212 e is known about how the blood and lymphatic microvasculature modulates cystogenesis.

213 reviously been suggested that the intestinal microvasculature network directs the migration of enteri

214 haemic tissue after stroke, associating with microvasculature, neurons and AD-plaques, Abeta, also, b

215 hat VEGF protects the retinal and glomerular microvasculature, not only through VEGFR2-mediated vascu

216 iently deposit 20-30mum large bubbles in the microvasculature, occluding blood flow for ~5-10min.

217 adult EC line (D3) derived from the cerebral microvasculature of a hippocampal biopsy.

218 CTH is likely to be high in the chaotic microvasculature of a tumor, increasing the effective sh

219 ing and VEGFR distribution were found in the microvasculature of brain and retina but not lung, indic

220 Using intravital microscopy of cremasteric microvasculature of chimeric LSP1-deficient mice, we sho

221 ed from GSCs as a significant contributor to microvasculature of glioblastoma and points to Flk-1 as

222 ls conspicuously accumulate within the liver microvasculature of healthy mice, crawling on the lumina

223 cally recognizes an epitope expressed in the microvasculature of human arthritic synovium and that ha

224 antibody, scFv A7, with specificity for the microvasculature of human arthritic synovium.

225 s used to isolate antibodies specific to the microvasculature of human arthritic synovium.

226 and vascular cell adhesion molecule-1 in the microvasculature of kidneys and liver, although messenge

227 Retinal microvasculature of MMP-KO mice, diabetic for approximat

228 get for reducing the oxidative milieu in the microvasculature of patients with CAD.

229 -mediated inflammatory disease affecting the microvasculature of skin and muscle.

230 ce of approximately 130 mum in the pulmonary microvasculature of the anesthetized mouse.

231 lation of infected erythrocytes (IEs) in the microvasculature of the brain caused by parasite adhesin

232 falciparum-infected erythrocytes within the microvasculature of the brain plays a key role in the de

233 tions of the same 5 gene families damage the microvasculature of the brain that leads to dementia.

234 The capability of pvOCT imaging of the microvasculature of the choriocapillaris and the anterio

235 in the ganglion cells, nerve fiber layer and microvasculature of the human retina.

236 Here we show that PMo are enriched in the microvasculature of the lung and reduce tumor metastasis

237 constitutively accumulate and reside in the microvasculature of the mouse lung.

238 st evident in the heart, particularly in the microvasculature of the outer myocardium, and was recapi

239 he versatility and clinical relevance of our microvasculature-on-a-chip model as a biophysical assay

240 scFv A7 antibody had no reactivity with the microvasculature or with other cellular components found

241 (iRBCs) to host endothelial receptors in the microvasculature, or cytoadhesion, is associated with se

242 g fluorescent tracer microspheres to compare microvasculature patterns.

243 n of S. lugdunensis was evaluated in a mouse microvasculature perfusion model and a new mouse model o

244 Extravasation rates and microvasculature permeabilities were significantly diffe

245 Beyond this metabolic dilation, the microvasculature plays a critical role in modulating vas

246 Infected erythrocyte sequestration in the microvasculature plays a critical role in the developmen

247 lial dysfunction and insulin resistance, and microvasculature plays a critical role in the regulation

248 ue hypoxia resulting in dysfunctional airway microvasculature precedes the airway fibrosis characteri

249 estration of parasitized erythrocytes in the microvasculature rather than reduction in circulating bl

250 155 inhibition after ischemia supports brain microvasculature, reduces brain tissue damage, and impro

251 nted, and electron microscopy of the retinal microvasculature region revealed normal mitochondrial ma

252 asodilator signalling across elements of the microvasculature remain an important area of focus for n

253 impact of prenatal alcohol exposure on brain microvasculature remains poorly understood.

254 ng disorders characterized by thrombi in the microvasculature resulting in thrombocytopenia, microang

255 umber of EPCs incorporated into the lesions' microvasculature, resulting in an improved early vascula

256 consequence, the geographical extent of the microvasculature's response to voltage-changing inputs i

257 Tumor microvasculature tends to be malformed, more permeable,

258 olution imaging of the retinal and choroidal microvasculature that compares favorably with FA.

259 nsit of oxygenated blood across the cortical microvasculature that significantly prolonged the evolut

260 y the effect of systemic risk factors on the microvasculature that was previously not accessible in a

261 ed formation, studies for the development of microvasculature, the connecting bridge between them, ha

262 e effects of full-length netrin-1 on retinal microvasculature, the VI-V fragment promoted vascular pe

263 nervation had a long-term effect on the limb microvasculature: The rapid and joint-localized vascular

264 cells with FGF9 can differentiate the tumor microvasculature to an extent not observed previously.

265 vasodilator response of the skeletal muscle microvasculature to insulin and exercise is of critical

266 mpair the vasodilator response of the muscle microvasculature to insulin, exercise and VEGF-A and red

267 ction, but also from impaired ability of the microvasculature to match oxygen delivery to increased o

268 -dimensional microfluidic model of the human microvasculature to recapitulate the environment wherein

269 optotic and anti-inflammatory roles in brain microvasculature to reduce ischemic cerebral vascular an

270 synthetic matrix, resulting in a functional microvasculature useful for the study of 3-dimensional v

271 To evaluate the retinal microvasculature using OCT-A in patients with type 2 dia

272 luate the ability of measurements of retinal microvasculature using OCTA to distinguish healthy eyes

273 on quantitative measurements of the retinal microvasculature using optical coherence tomography angi

274 asibility of rendering retinal and choroidal microvasculature using PV-OCT was compared qualitatively

275 f parasite-infected red blood cells in brain microvasculature utilizes host- and parasite-derived adh

276 tereology of brain, eye, and skeletal muscle microvasculature was evaluated in control and diabetic r

277 as systemically administered, patency of the microvasculature was maintained.

278 Retinal microvasculature was measured using computer software (S

279 logical fluid shear stresses observed in the microvasculature was shown to reduce neutrophil activati

280 confirmed that sequestration in the cerebral microvasculature was significantly higher in patients wi

281 To further resolve the tumor microvasculature, we performed correlated UM of fluoresc

282 Quantitative parameters from the retinal microvasculature were measured on binarized and skeleton

283 dothelial (L-E) interactions in the cerebral microvasculature were then quantified in vivo using intr

284 between retinoblastoma cells and surrounding microvasculatures were studied using a transgenic zebraf

285 a landmark microanatomical structure at the microvasculature where cancer cells enter the blood stre

286 In the microvasculature, where erythrocytes infected with P fal

287 ifferent signals during the contact with the microvasculature, which activate signaling pathways lead

288 ples of these structures include neurons and microvasculature, which can take the form of both hierar

289 s muscle insulin uptake by recruiting muscle microvasculature, which contributes to its insulin-sensi

290 e leads to sequestration of infected RBCs in microvasculature, which enables the parasite to evade th

291 the electrotonic architecture of the retinal microvasculature, which is particularly well adapted for

292 the creation of self-supporting multilayered microvasculature with a distinct circular lumen followin

293 les across tumor and non-tumor mammary gland microvasculature with and without application of RF hype

294 A key factor is tumor microvasculature with complex effects including convecti

295 We examined the retinal microvasculature with swept-source OCT-A and a semiautom

296 s of HDL/ApoA-I may connect the pathology of microvasculature with that of large vessels (atheroscler

297 licle, and degeneration and atrophy of brain microvasculature with visual evoked potential anomalies.

298 ulting in a profound diminution of the brain microvasculature without compromising the blood-brain ba

299 that can visualize the retinal and choroidal microvasculature without the injection of exogenous dyes

300 ography (OCT-A) is able to visualize retinal microvasculature without the need for injection of fluor