ライフサイエンスコーパス: middle

1 (rWORLD-High), and middle-income countries (Middle).

2 ed from low (27.2; 95% CI, 26.5-27.9) to low-middle (27.9; 95% CI, 27.4-28.5), high-middle (29.2; 95%

3 o low-middle (27.9; 95% CI, 27.4-28.5), high-middle (29.2; 95% CI, 28.6-29.7), and high (31.8; 95% CI

4 ues were grouped by tertiles (lower 132-298, middle 299-338, higher 339-400 dB/m).

5 A decreasing BMI from early to middle age and a low BMI in middle age may be positively

6 MI from early to middle age and a low BMI in middle age may be positively associated with ALS risk.

7 have an increased brain amyloid load at late middle age.

8 reduce the risk of incident hypertension in middle age.

9 ccelerates these effects in apoE4-TR mice at middle age.

10 ly determine cardiovascular disease (CVD) by middle age.

11 n older adults may hold promise for those in middle age.

12 ies are particularly pronounced in young and middle age.

13 Studies in middle-age and older (masters) athletes with atheroscler

14 Recolonizing the gut of middle-age individuals with bacteria from young donors r

15 BMD reduction over a 8-year follow-up of 692 middle-aged (46.7+/-12.3 yrs), low-income BACH/Bone coho

16 Young (18-49 years) and middle-aged (50-64 years) patients were 2 to 8 times mor

17 Middle-aged (9-11 months) transgenic animals (both male

18 age of 20%), whereas estimates for young and middle-aged adults varied by country and were potentiall

19 ween 1964 and 1973 when the individuals were middle-aged and 1996 and 2015 when participants were in

20 rum bilirubin levels and incident T2D in the middle-aged and elderly adults; instead, direct bilirubi

21 Free thyroxine levels in middle-aged and elderly subjects were positively associa

22 In total, 231 middle-aged and older adults (167 women [72.3%] and 64 m

23 poral trends in serum PFAS levels among 1257 middle-aged and older California women (ages 40-94) duri

24 s to the variation in the number of teeth in middle-aged and older populations using a population-bas

25 d importantly affects tooth loss in both the middle-aged and the older populations.

26 cial disparity in diabetes incidence between middle-aged black and white individuals.

27 We hereby report a case of a middle-aged female who was subsequently diagnosed with l

28 ears or younger than 12 years as compared to middle-aged human subjects.

29 Many CVRF-free middle-aged individuals have atherosclerosis.

30 sion in the CA1 region of the hippocampus of middle-aged male mice using a viral vector rejuvenates h

31 hickness) in an independent sample cohort of middle-aged men with subclinical cardiovascular disease

32 ducing PERK expression in the hippocampus of middle-aged mice enhances hippocampal-dependent learning

33 tion increased with advancing age, such that middle-aged mice showed much more pronounced differences

34 Case Report: Our case is of a middle-aged multiparous female who presented with amenor

35 ding 850 younger patients (<50 years), 2,540 middle-aged patients (50-69 years) and 1,542 elder patie

36 Most patients were middle-aged white men.

37 depression and incident cardiac events among middle-aged workers from the GAZEL cohort.

38 base wine and the wine samples taken in the middle and at the end of fermentation.

39 This was true for low/middle and high income sites.

40 o3, outer hair cells are lost throughout the middle and higher frequencies.

41 hin the biofilm architecture (i.e., surface, middle and interior of the biofilm).

42 nt regions of Britain and Ireland during the middle and later Holocene.

43 lly, cross-compartment coherence between the middle and ring-little fingers tended to be higher as co

44 which are structurally homologous to the RPA middle and small subunits, respectively.

45 Because of the growing number of pigeons in Middle and Southern Europe cities, some cases of idiopat

46 al backbone that connects the Mediator head, middle and tail modules.

47 ia sinensis from calcareous mudstones of the middle and upper part of the Kaili Formation (Cambrian S

48 of Pol contains a three-helix bundle in the middle and zinc-binding modules on each side.

49 3.5, and 3.6 mm Hg lower systolic BP in low, middle, and high genetic risk groups, respectively (P fo

50 ded into quartiles for low, low-middle, high-middle, and high income inequality.

51 ies in afterschool settings with elementary, middle, and high school students.

52 c resonance imaging scans at 3 times (early, middle, and late adolescence) from ages 11 to 20 years.

53 ine were identified, corresponding to early, middle, and late timing of maximal FEV1 loss, in the ove

54 s was 9% (n = 11), upper back; 29% (n = 35), middle back; 51% (n = 61), lower back; and 11% (n = 13),

55 We conducted a multilevel (Top-Middle-Bottom-Up) approach focusing on the characterizat

56 p, Xandarella mauretanica sp. nov., from the middle Cambrian (Stage 5) Tatelt Formation of Morocco, m

57 ion were calculated for DN-to-pons and DN-to-middle cerebellar peduncle (MCP) ratios in a region-of-i

58 ain parenchyma, hydrocephalus, and so-called middle cerebral artery (MCA) "pseudofeeders" were correl

59 We included 67 patients with malignant middle cerebral artery [MMCA] stroke who underwent decom

60 h after stroke induction by occlusion of the middle cerebral artery markedly reduced infarct size, an

61 eeks, the animals were subjected to a 2-hour middle cerebral artery occlusion (MCAO) and sacrificed a

62 mice were subjected to 60 min of reversible middle cerebral artery occlusion and evaluated for infar

63 of amyotrophic lateral sclerosis (SOD1G93A), middle cerebral artery occlusion, and multiple mini-stro

64 ith ischemic stroke and in mice subjected to middle cerebral artery occlusion, natural killer (NK) ce

65 g photothrombotic cortical injury, transient middle cerebral artery occlusion, or neonatal hypoxic-is

66 Cerebral ischemia was induced by middle cerebral artery occlusion.

67 onclusion In this study, patients with acute middle cerebral artery stroke with absence of cortical v

68 fected white matter tracts, and involved the middle cerebral artery territory for 112 patients (73%).

69 acranial internal carotid artery or proximal middle cerebral artery who had last been known to be wel

70 Labbe, sphenoparietal sinus, and superficial middle cerebral vein was graded by one neuroradiologist,

71 er of 2003, 2004, and 2005) and again during middle childhood (2009-2011) for a follow-up assessment

72 is also required in three later phases: the middle childhood growth and consolidation phase (5-9 yea

73 does not exhibit age-related variation from middle childhood to late adolescence.

74 connectivity between amygdala and posterior middle cingulate cortex was found in female patients but

75 ral lobule, the superior temporal gyrus, the middle cingulate gyrus, the putamen and the superior par

76 we recorded neurons in three color patches, middle color patch CLC (central lateral color patch), an

77 ircuit motif of a core thalamic input to the middle cortical layer and that thalamocortical synapses

78 hospital survival was significantly lower in Middle countries than in Europe-High or rWORLD-High coun

79 ave originated before or near the end of the Middle Devonian epoch (around 385 million years ago).

80 fic bedding plane assemblages from the Lower-Middle Devonian Kwataboahegan Formation of Ontario, Cana

81 ctivating co-chaperone Aha1 from binding the middle domain of Hsp90.

82 NBD) of DnaK interacted with a region in the middle domain of Hsp90Ec.

83 DnaB is composed of an N-terminal domain, a middle domain, and a C-terminal domain.

84 n dimerization and involving a region of the middle domain/carboxy-terminal domain interface previous

85 ia head-to-head contacts between coiled-coil middle domains (MDs).

86 ocated into 5 groups: BSJYD high dose group, middle dose group, low dose group, captopril group, and

87 signaling in patterning the stapes and incus middle ear bones derived from the equivalent pharyngeal

88 The middle ear conducts sound to the cochlea for hearing.

89 Studies in the chinchilla model of middle ear infection demonstrated that VP1 is a virulenc

90 ability to cause both nasal colonization and middle ear infection.

91 phy (HRCT) and MRI are helpful in evaluating middle ear pathologies, usage being indication specific.

92 terpreted to be for gliding and a mandibular middle ear with a unique character combination previousl

93 rophone for totally implantable cochlear- or middle-ear hearing aids.

94 elson interferometer, designed to serve as a middle-ear microphone for totally implantable cochlear-

95 projected to increase in Australia (9%), the Middle East (14%), and central Asia (16%) and decline in

96 tries in Asia (South Korea pooled: 206), the Middle East (Turkey pooled: 160), and Southern America (

97 iency, the disease is far more common in the Middle East and North Africa, where consanguinity is com

98 man pathogen that is the causative agent for Middle East respiratory syndrome (MERS).

99 severe acute respiratory infection from the Middle East respiratory syndrome and to compare these fe

100 To date, 1841 cases of Middle East respiratory syndrome coronavirus (MERS-CoV)

101 Middle East respiratory syndrome coronavirus (MERS-CoV)

102 Middle East respiratory syndrome coronavirus (MERS-CoV)

103 Middle East respiratory syndrome coronavirus (MERS-CoV)

104 Middle East respiratory syndrome coronavirus (MERS-CoV)

105 Middle East respiratory syndrome coronavirus (MERS-CoV)

106 regulating MERS-CoV pathogenesis in vivo The Middle East respiratory syndrome coronavirus (MERS-CoV)

107 from the 2002-2003 SARS epidemic and recent Middle East respiratory syndrome outbreak indicate that

108 Although Middle East respiratory syndrome severe acute respirator

109 on patients were younger than those with non-Middle East respiratory syndrome severe acute respirator

110 tation and comorbidities among patients with Middle East respiratory syndrome severe acute respirator

111 Patients with Middle East respiratory syndrome severe acute respirator

112 dently associated with death compared to non-Middle East respiratory syndrome severe acute respirator

113 djustment for potential confounding factors, Middle East respiratory syndrome was independently assoc

114 ndrome-associated coronavirus (SARS-CoV) and Middle East respiratory syndrome-associated coronavirus

115 cute respiratory syndrome (SARS)-CoV and the Middle East respiratory syndrome-CoV, cause acute respir

116 In the Middle East, genotype 4 HCV infection is the most common

117 North America and Europe, South America, the Middle East, south Asia, China, southeast Asia, and Afri

118 h heart failure in Africa, China, India, the Middle East, southeast Asia and South America; we also e

119 t, have been detected in East Africa and the Middle East, where they lead to substantial economic los

120 -use disorder and 'pharmacoterrorism' in the Middle East.

121 ed paternal contribution from Europe and the Middle East.

122 wel syndrome (IBS) and its correlates in the Middle East.

123 ts, we used a hypothetical case example of a Middle Eastern adolescent patient with incurable cancer

124 Cumulatively, the emerging profile is of a Middle Eastern ancestor, self-affiliating as Levite, and

125 rporating (1) evidence from both Western and Middle Eastern medical literature and (2) theories of cu

126 We describe a botulism outbreak involving 4 Middle Eastern men complicated by delayed diagnosis, amb

127 feature of the sedimentary record since the middle Ediacaran ( 580 million years ago).

128 icate deep-ocean oxygenation occurred in the middle Ediacaran, coinciding with the onset of widesprea

129 sequentially without the need of adopting a middle electrode and orthogonal solvents.

130 existed at the Sabrina Coast by the early to middle Eocene epoch.

131 treatment era (ie, studies before 1946), the middle era (1946-80), and the recent era (after 1980).

132 aised dot patterns passing under their right middle finger.

133 e features in regions both vulnerable in the middle frontal and inferior temporal gyri (MFG and ITG)

134 time and brain activity in the inferior and middle frontal gyri, precuneus, cingulate cortex, caudat

135 ctional connectivity (iFC), highlighting the middle frontal gyrus (MFG) for both competencies.

136 ng trend towards reduced TSPO binding in the middle frontal gyrus of patients with recent-onset schiz

137 ent stimulation group, with no change in the middle frontal gyrus or parietal cortices.

138 Within the middle frontal gyrus, decrements in linoleic acid, linol

139 in the left pars orbitalis inferior-frontal, middle-frontal, and inferior-parietal regions preceded b

140 tion in a cohort of 1,167 individuals in the Middle Gangetic Plain of the Indian subcontinent.

141 teractions are most strongly enriched in the middle genomic distance range ( approximately 700 kb-1.5

142 The middle ground tissue layer comprises the majority of the

143 ersampled for elevated brain Abeta, both the middle (hazard ratio [HR], 2.43; 95% CI, 1.25-4.72) and

144 odes was divided into quartiles for low, low-middle, high-middle, and high income inequality.

145 erms of applicability to settings in low and middle income countries is questionable.

146 ns a major challenge for patients in low and middle income countries.

147 f low income, lower-middle income, and upper-middle income covering the majority of these adolescents

148 nvestments in countries of low income, lower-middle income, and upper-middle income covering the majo

149 ries of high income and countries of low and middle income.

150 Life expectancy has risen among middle-income and high-income Americans whereas it has s

151 e countries and and occurs at lower rates in middle-income and high-income countries.

152 ll remains the leading cause of blindness in middle-income and low-income countries.

153 tients with sepsis across different low- and middle-income clinical settings and patient populations.

154 ds, are critical, particularly from low- and middle-income contexts where the highest burden of still

155 re due to infections, especially in low- and middle-income contexts.

156 e-income countries (90 of 126), 47% in lower-middle-income countries (107 of 227), and 13% in low-inc

157 ties), 76% in India (68 of 90), 71% in upper-middle-income countries (90 of 126), 47% in lower-middle

158 METHODS AND Model inputs for 7 low- and middle-income countries (Brazil, Colombia, Ecuador, Ghan

159 pollutant concentrations than low-income and middle-income countries (LMICs) and different sources of

160 diagnosed in women living in low-income and middle-income countries (LMICs), where opportunities for

161 e is a rapidly growing challenge in low- and middle-income countries (LMICs).

162 IV) drug resistance (HIVDR) in many low- and middle-income countries (LMICs).

163 control of the HIV-AIDS epidemic in low- and middle-income countries (LMICs).

164 ght compromise HIV control in low-income and middle-income countries (LMICs).

165 om researchers and policy-makers in low- and middle-income countries (LMICs).

166 ond to EIDs is typically weakest in low- and middle-income countries (LMICs).

167 in the rest of the world (rWORLD-High), and middle-income countries (Middle).

168 nd health yet many water systems in low- and middle-income countries are nonfunctional.

169 ction (STEMI) care are formidable in low- to middle-income countries because of several system-level

170 ver of increased intakes of UPFDs in low- to middle-income countries but rather that this is driven b

171 could be a starting place for low-income and middle-income countries developing universal health cove

172 proportion of communities in low-income and middle-income countries do not have access to more than

173 population with severe pneumonia in low- and middle-income countries has not been described.

174 om traditional cooking practices in low- and middle-income countries have detrimental health and clim

175 on climate-related health issues in low- and middle-income countries need to continue to prepare them

176 al linear growth faltering in low-income and middle-income countries should prioritise action on comm

177 ic burden as percentage of GDP was larger in middle-income countries than in high-income countries.

178 Data from middle-income countries that have both low- and high-inc

179 The limited capability in most low- to middle-income countries to study the benefit of pneumoco

180 ns, drawing mainly on experience in low- and middle-income countries where undernutrition and poor ch

181 In low- and middle-income countries, adaptive policies achieve simil

182 ed perceived stress among people in low- and middle-income countries, and that the poorest persons ma

183 of mental health problems occurs in low-and-middle-income countries, but few epidemiological studies

184 f slums to argue that, in all low-income and-middle-income countries, census tracts should henceforth

185 In low- and middle-income countries, community-level surgical epidem

186 valence studies are sparse in low-income and middle-income countries, elder abuse seems to affect one

187 In low-income and middle-income countries, invasive mechanical ventilation

188 mited data were available for low-income and middle-income countries, our findings suggest that large

189 For lower-middle-income countries, the mortality reduction from im

190 controlled trials done in 14 low-income and middle-income countries, which compared multiple micronu

191 ies are common among women in low-income and middle-income countries.

192 the SDGs for China and other low-income and middle-income countries.

193 e to HIV-positive patients in low-income and middle-income countries.

194 ange experienced in China and other low- and middle-income countries.

195 ention of mental disorders in low-income and middle-income countries.

196 shed multinational cohorts in low-income and middle-income countries.

197 or features of cities in many low-income and middle-income countries.

198 s (HIV) have been scaled up in many low- and middle-income countries.

199 t few data are available from low-income and middle-income countries.

200 supply (IWS) is prevalent throughout low and middle-income countries.

201 om controls in 9 diverse sites in 7 low- and middle-income countries.

202 rotypes that are important in low-income and middle-income countries.

203 omes, and infant mortality in low-income and middle-income countries.

204 ities and multimorbidities in low-income and middle-income countries.

205 or control of hypertension in low-income and middle-income countries.

206 es compared with reports from low-income and middle-income countries.

207 en of disease posed by influenza in low- and middle-income countries.

208 men globally, particularly in low-income and middle-income countries.

209 care to address syndemics in low-income and middle-income country settings.

210 to increase breast health-care capacity in a middle-income Latin American country.

211 In upper-middle-income nations, NRDs are associated with slight d

212 The adaptive policy optimized for middle-income resource settings yields 0.008 fewer QALYs

213 sease from 613 communities in 18 low-income, middle-income, and high-income countries in seven geogra

214 n., from the late Middle Jurassic Jiulongshan Formation of Daohugou, Inner

215 n feeding and/or pollination during the late Middle Jurassic, much earlier than the appearance of ang

216 are filled with parallel nanosheets and the middle layer is filled with vertical nanofibers.

217 wavelength and color signals project to the middle layers of V1.

218 ensive microscopy and radiography network at middle levels of the health system, a quarter of all not

219 how the precise topography of the long (L)-, middle (M)-, and short (S)-wavelength-sensitive cones in

220 betan Plateau (QTP) and climate changes from Middle Miocene onwards in promoting species diversificat

221 ibed, recovered from the 13 million-year-old Middle Miocene site of Napudet, Kenya.

222 the Isthmus was effectively complete by the middle Miocene, 13 Ma.

223 e ring-like lignin polymers deposited in the middle of anticlinal cell walls between endodermal cells

224 ommunities of dairy cows from 2 weeks to the middle of first lactation (>2 years) as well as rumen-as

225 e trains on single electrodes at the apex or middle of long electrode arrays.

226 Situated within the middle of the BER pathway, Pol beta must efficiently loc

227 ingle lipid-facing arginine residue near the middle of the beta barrel of the Escherichia coli OMPs O

228 otentials (500-700 mV in DMF measured at the middle of the catalytic wave).

229 eholds in Greeley, Colorado, which is in the middle of the densely developed Denver-Julesburg basin.

230 at lagging-strand extrusion initiates in the middle of the DH that is composed of the zinc finger dom

231 data explain how R696 is accommodated in the middle of the membrane while reporting the overall stabi

232 re measured when tyrosine was located in the middle of the peptide chain.

233 d by either bulging out of the groove in the middle of the peptide or by binding in a zigzag fashion

234 pattern with the presence of a notch in the middle of the QRS in all cases, precordial transition at

235 rther, we show that a triple mutation in the middle of the transmembrane (TM) segment of KCNE3 introd

236 el use, if unabated, risks taking us, by the middle of the twenty-first century, to values of CO2 not

237 embrane domain result in a sharp kink in the middle of transmembrane helix 6, which pivots its intrac

238 c polyriboinosinic-polyribocytidylic acid in middle or late gestation.

239 ort of a severely injured trilobite from the Middle Ordovician ( 465 Ma) accords with a number of sim

240 The late Middle Palaeolithic (MP) settlement patterns in the Leva

241 g properties to facial features found in the middle patch of face processing in IT as documented by F

242 e coding principle of facial features in the middle patch of face processing in the macaque IT cortex

243 spore contour, followed by re-location to a middle peripheral spore region.

244 The Middle Pleistocene is a crucial time period for studying

245 cative of greater mtDNA diversity during the Middle Pleistocene than in later periods.

246 ggest an archaic human diaspora early in the Middle Pleistocene.

247 roughout the protein and are dominant in the middle portions of the TM helices.

248 % CI: 0.018, 0.066; P = 0.001), those in the middle predicted benefit subgroup had a NNT of 76 (ARR =

249 The middle Pro residue within the tripeptides was replaced w

250 Individuals in the middle quintile of neonatal 25(OH)D3 had lower odds of s

251 issociation (EThcD), for characterization of middle-range sized peptides.

252 nt in lower section of the upper reaches and middle reaches because of intensive agricultural activit

253 solved nitrogen flux was 7.2 times higher in middle reaches than that at head waters.

254 t that in addition to the well-characterized middle region of MAD1 containing the MAD2-interaction mo

255 Its upper and middle regions have adequate hydration and H-bonding res

256 he tuber inner cores softening more than the middle regions.

257 asymmetric deletions and large insertions of middle repetitive sequences.

258 inform interventions, especially in low- and middle-resource contexts.

259 ores on standardized tests in elementary and middle school, gifted status, and low performance.

260 0 000], education [primary school and below, middle school, high school, and college and above], prev

261 high schools (95% CI, 7.7%-17.5%), 18.2% of middle schools (95% CI, 13.3%-24.4%), and 14.7% of eleme

262 high schools (95% CI, 29.7%-46.0%), 51.6% of middle schools (95% CI, 43.3%-59.7%), and 49.5% of eleme

263 were less likely than elementary schools and middle schools to adopt several practices: for instance,

264 sk singleton pregnancies of women of high or middle socioeconomic status and without known environmen

265 A weighted average age places these Middle Stone Age artefacts and fossils at 315 +/- 34 tho

266 The earliest Middle Stone Age assemblages come from eastern and south

267 contains one of the earliest directly dated Middle Stone Age assemblages, and its associated human r

268 Jebel Irhoud the oldest and richest African Middle Stone Age hominin site that documents early stage

269 sponsible for the production of Acheulean or Middle Stone Age tool industries.

270 previously unknown critical function of the middle subunit in CAF-1.

271 The gene coding for middle T antigen (MT) is the murine polyomavirus oncogen

272 Middle T antigen (MT), the principal oncoprotein of muri

273 The polyomavirus middle T antigen (PyMT) oncogene activates the cellular

274 d with the Mouse Mammary Tumor Virus-Polyoma Middle T-Antigen mouse.

275 Although polyoma virus middle T-driven tumors showed altered primary and metast

276 /- 4.7 Mha (62%) were distributed across the middle taiga bioclimatic zone.

277 perceptual decision-making, responses in the middle temporal (MT) and lateral intraparietal (LIP) are

278 motion perception and neural activity in the middle temporal (MT) area of the macaque monkey to study

279 SN by examining modulatory influences in the middle temporal area (MT) of the macaque visual cortex,

280 ecord neuronal spiking activity in the human middle temporal gyrus (MTG), a cortical region supportin

281 This modulation was mainly detected in the Middle Temporal Gyrus and within regions related to the

282 Greater activation in the precuneus and middle temporal gyrus predicted lower weight variability

283 r temporal region and its connections to the middle temporal gyrus, inferior temporal gyrus, and cing

284 ortance within these pathways: the posterior middle temporal gyrus, thought to serve as a lexical int

285 ral prefrontal cortex (DLPFC), and bilateral middle temporal gyrus.

286 gitudinal changes in ADAS-cog score and left middle temporal thickness and amygdalar volume (Pone-tai

287 auditory hallucination; (ii) left superior-/middle-temporal gyri and receptive aphasia; (iii) widesp

288 idea that there was only a single species of middle to late Pleistocene NWSL equid, and demonstrate t

289 eological site that provides evidence of the Middle to Upper Palaeolithic transition in Iran.

290 marine reptile (Dinocephalosaurus) from the Middle Triassic ( approximately 245 million years ago) o

291 eservation in Yunnanolimulus luopingensis, a Middle Triassic (ca. 244 million years old) horseshoe cr

292 The Middle Triassic age and lack of the characteristically-e

293 nov., from the Middle Triassic epoch.

294 The close anatomical similarity between the Middle Triassic horseshoe crabs and their recent analogu

295 eton of Diandongosuchus fuyuanensis from the Middle Triassic of China as the oldest and basalmost phy

296 strial vertebrate diversity recovered by the Middle Triassic, and that diversity was now dominated by

297 , the proximal ubiquitin is connected to the middle ubiquitin via K48 and these two ubiquitins adopt

298 stuzumab B, and Erbitux/Cetuximab B) using a middle-up approach.

299 CAP tertiles (7.2% in lower versus 16.6% in middle versus 18.1% in higher).

300 d in human cones, i.e. long-wavelength (L)-, middle-wavelength (M)-, and short-wavelength sensitive (