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1 e to monetary reward as constrained by sleep midpoint.
2 pendent gating curve as well as shifting the midpoint.
3 SpoIIIE translocation complex at the septal midpoint.
4 epolymerization did not alter the activation midpoint.
5 e was positioned above or below the stimulus midpoint.
6 mixer at temperatures far below the thermal midpoint.
7 ms a ringlike structure (Z-ring) at the cell midpoint.
8 out thermal energy ( RT) at the denaturation midpoint.
9 od solvent conditions and at this transition midpoint.
10 s back to two-state folding at its unfolding midpoint.
11 contractile ring ingressed past the spindle midpoint.
12 imiting capacity was reached near the column midpoint.
13 t for the observed patterns of species range midpoints.
14 lly failed to predict the pattern of species midpoints.
15 atial patterns of species richness and range midpoints.
16 completed by blind raters at baseline and 5 (midpoint), 10 (end of treatment), and 14 weeks (follow-u
17 new or worse cystoid changes after the study midpoint (13 surgical eyes [54.2%] vs 9 nonsurgical eyes
19 ndividuals at the lowest mtDNA/nDNA quartile midpoint (4.68 mm Hg; 95% CI, 3.03-6.33; P<0.0001), in c
24 t baseline and significantly higher than the midpoint and end-of-treatment rates in the control group
26 he age ranges of prebomb sharks (reported as midpoint and extent of the 95.4% probability range) reve
27 il to engineer mutants L1 and L2 and deleted midpoint and head-proximal sigma1 IDRs to generate Delta
28 re collected in the fall (baseline), winter (midpoint), and spring (end point) of the 2009-2010 schoo
30 te and cocoa or placebo)-by-trial (baseline, midpoint, and end-of-treatment assessments) interactions
32 e concentrations were collected at baseline, midpoint, and endpoint to assess the mechanism of action
34 of all BC bottles inoculated with the peak, midpoint, and trough concentrations, respectively (P </=
39 the early Eocene, providing a geochronologic midpoint assessment of bee pollen-collection strategies.
40 ic reduction of d-Ala-d-Ala, with a response midpoint at approximately 0.06mug/ml vancomycin and with
44 anosensitive cells increased rapidly, with a midpoint at postnatal day 0 for basal cells, and correla
46 nts of species may be drawn towards a single midpoint attractor - a unimodal gradient of environmenta
47 to estimate the location and strength of the midpoint attractor from species occurrence data sampled
50 late oxygens lie more than 4 A away from the midpoint between the nitrogen atoms, indicating that a s
51 y, near the oil sands industrial center (the midpoint between the Syncrude and Suncor upgrader stacks
53 the spindle to position itself at the exact midpoint between the two sets of segregating chromosomes
55 In this task, monkeys tracked the invisible midpoint between two peripheral bars, such that the visu
56 of mitochondrial dysfunction at the disease midpoint but suffer from a severe deficit in mitochondri
57 Z normally assembles into a ring at the cell midpoint, called the Z ring, which is oriented perpendic
58 ere both response sensitivity and transition midpoint can be tuned with high precision over the physi
59 pactful stages of the life cycle across nine-midpoint categories, a payback period and uncertainty an
60 nts a methodology that can be used to derive midpoint characterization factors for water deprivation
61 aA3[IV] mutants) exhibited higher transition midpoints compared to the transition midpoints of the mu
62 e the case of annulenes, in which bond-shift midpoints correspond to transition states, for transform
63 nd 70 degrees C were observed, for which the midpoints could be determined accurately by sigmoidal fi
65 compounds 14-17 and 19 exhibited mean graph midpoint cytotoxicity (GI50) values of 21-71 nM in the N
66 correlation between the paired incisions for midpoint depth and side cut angle (correlation coefficie
67 ere 20% uncut anterior, 20% uncut posterior, midpoint depth of 50%, and 90 degrees side cut angle.
70 or, and 42.3+/-6.6% (range, 25.5%-65.4%) for midpoint depth, which all were significantly different f
73 rric aquo-heme and aquo-heme electrochemical midpoints (E(m)s) at pH 7 in sperm whale myoglobin, Aply
77 the CaDPA band intensity to decrease to the midpoint from its initial value, was found to be stochas
79 sess the impacts of its process chains on 17 midpoint impact categories using ReCiPe-2008 methodology
80 roduce the Precipitation Reduction Potential midpoint impact representing the change in downwind prec
82 to-gate assessment results indicate that the midpoint impacts associated with producing CNTs are marg
83 rade-offs in energy return on investment and midpoint impacts relative to the base case while remaini
84 de or direction of phase shifts of melatonin midpoint in response to 2 h of light at either 2000 lux
85 t; the difference in the temperature of this midpoint in the presence and absence of ligand is relate
87 h of the following criteria: data collection midpoint in year 1998 or later, study period of a 12-mon
88 eases in monolayers and shifts in activation midpoints in patch-clamp experiments suggested that the
89 possible to consistently link the developed midpoint indicators with a later endpoint assessment alo
90 ipient downhill folder even at the unfolding midpoint (k(m)(-1) approximately 2 micros, k(a)(-1)=15 m
94 linded research personnel at baseline, study midpoint (median, 6.8 months), and study completion (med
96 he new compounds had cytotoxicity mean-graph midpoint (MGM) GI50 values in the submicromolar (0.033-0
97 dependence overlaps that of I(A) activation (midpoint near -44 mV) and inactivation (midpoint near -8
101 the epicardial border of the LV apex and the midpoint of a line connecting the origins of the mitral
102 mitochondria, produced by platelets, at the midpoint of a potent mechanism leading to inflammatory r
104 of maximal stenosis and at the rostrocaudal midpoint of a spindle-shaped T2 hyperintensity suggests
105 reas voltage sensor-bound lipids shifted the midpoint of activation dependent on their electrostatic
109 d, with %CVs ranging from 2.7 to 7.8%, and a midpoint of approximately 17 ng/ml with further optimisa
111 ontaining the native CNG channels shifts the midpoint of cGMP dependence from approximately 91 muM in
113 dPR), 25% to 75% of diastole (dPR25-75), and midpoint of diastole (dPRmid), along with Matlab calcula
114 al, in which a single reversal occurs at the midpoint of each session, consistently show anticipation
116 yl-L-ornithine, was synthesized and showed a midpoint of inhibition at approximately 22 nM; this comp
118 nent (OT3), was affected by ethanol with the midpoint of its dose-response curve moved to lower stero
119 lies on determining the pK parameter, the pH midpoint of peptide insertion into the lipid bilayer.
122 by a single deprotonation and occurs with a midpoint of pH 8.8, but surprisingly, the intermediate f
124 In Experiment 3, pigeons searched at the midpoint of rotated arrays in both the presence and abse
125 cid accounts for a nearly 50 mV shift in the midpoint of the activation curve in a direction consiste
127 Introduction of a flexible hinge at the midpoint of the beta3 TMD decoupled the talin-induced ch
130 her, which can result in both a shift of the midpoint of the dose-response curve and a change of the
133 ways, both of which involved cleavage at the midpoint of the hexamer, correlated with the stereochemi
134 trained to search for a goal located at the midpoint of the hypothetical line connecting two discret
136 ows a hydrophobic layer of about 10 A at the midpoint of the membrane bilayer, which is likely the mo
137 bunit carries a glutamate exposed around the midpoint of the membrane on the external surface of the
140 II redox couple such that it is close to the midpoint of the O2*- reduction and oxidation couples.
141 n miners and with a shorter time between the midpoint of the period of substantial exposure and diagn
144 he maximum deformation occurs at roughly the midpoint of the reaction, while further dimerization cau
146 loid peptide production by cleavage near the midpoint of the single transmembrane (TM) segment of APP
147 we depleted two proteins that mark the exact midpoint of the spindle during late anaphase, CYK-4 and
148 of the spindle and completed scission at the midpoint of the spindle, even when spindle length or rat
150 o 125-fold, with an average of 6-fold at the midpoint of the treatment to 12-fold after 12 weeks.
151 te a computerised task identifying perceived midpoint of the two glasses (order counterbalanced).
152 Hoff enthalpy and entropy of unfolding, the midpoint of the unfolding transition and the free energy
154 on, because ICA-105574 (2 microM) shifts the midpoint of the voltage-dependence of inactivation by >1
155 quired the studies to have a data collection midpoint of the year 2000 or later, to be done in full-y
158 he Azoarcus ribozyme is less flexible at the midpoint of transition in low-charge-density ions than i
160 ational transition (below 35 degrees C), the midpoint of which shifts to higher temperature (above 35
161 toms forming a cube, in which O atoms are at midpoints of all of its edges, in excellent agreement wi
163 cture form only transiently and are at their midpoints of stability at the boundary region between th
164 nsition midpoints compared to the transition midpoints of the mutant protein with the C-terminal doma
167 e than the naturally occurring protein, with midpoints of thermal denaturation greater than 99 degree
168 , M129K, and M129C did not affect stability (midpoints of thermal denaturation, T(m) = 65-66 degrees
170 analysed according to the time of melatonin midpoint on the nights before and after light exposure.
172 s are actively positioned either at the cell midpoint or cell poles, but the processes which drive in
173 not significantly increase from baseline at midpoint or end of study (4.1 +/- 0.6, 4.3 +/- 0.3, and
174 ed by fresh whole blood containing the peak, midpoint, or trough plasma concentrations for meropenem,
175 transcription start sites (TSSs) or enhancer midpoints, our analyses show that different locations di
176 rochemical technique was used to measure the midpoint oxidation-reduction potential of PdR that had b
178 ird deprotonations, with a combined apparent midpoint pH of 10.2, induce transitions to Lys73- or Lys
180 uch as ChIP-seq reads elongation, nucleosome midpoint piling strategy for positioning analyses, or th
181 .06 and g perpendicular = 1.92), but the low midpoint potential (< -570 mV) and instability of the re
182 The mutations had opposite effects on heme midpoint potential (-302, -361, and -427 mV for W66H, wi
188 nstrated that it is reversibly redox-active (midpoint potential -474.5 mV), indicating that it has th
191 c1 complex with Lys and Leu lowers the redox midpoint potential but not enough to prevent physiologic
192 O absorbance spectra, but increased the heme midpoint potential by 88 mV relative to wild-type iNOSox
193 how that the regulatory disulfide bond has a midpoint potential comparable with other known redox-res
195 semiquinone by reducing the electrochemical midpoint potential for its formation via the one-electro
197 avior, and the effects of pH on the observed midpoint potential indicated that reductive activation o
199 helix bundles that display pH-dependent heme midpoint potential modulations, or redox-Bohr effects.
201 ling between the Fe(III)/Fe(II) forms with a midpoint potential of +36 +/- 15 mV at pH 7.8 (versus NH
203 pair of quasi-reversible redox peaks with a midpoint potential of -0.225 V and -0.075, cathodic and
207 al of -310 mV via Mia40 with an intermediate midpoint potential of -290 mV to the C130-C133 pair of E
208 trons flowed from Tim13 with a more negative midpoint potential of -310 mV via Mia40 with an intermed
209 d that the AdoMet radical cluster exhibits a midpoint potential of -510 mV, while the auxiliary clust
210 ndicates a one-electron redox feature with a midpoint potential of -550 mV, which is assigned to a [4
211 0 mV, while the auxiliary cluster exhibits a midpoint potential of -765 mV, to our knowledge the lowe
214 nduced spectrometry, we show that PioC has a midpoint potential of 450 mV, contains all the typical f
216 which significantly contributes to the redox midpoint potential of H and the formation of the charge-
218 A detailed study of the pH dependence of the midpoint potential of skeletal horse myoglobin (Mb) with
219 activity-based titrations indicate that the midpoint potential of the disulfide in AtAPSK is compara
221 binding to cyt c(1) substantially lowers the midpoint potential of the heme and fully inhibits bc(1)
222 o high light, which coincides with a lowered midpoint potential of the Q(A)/Q(A)(-) redox couple and
226 y found in an intracellular environment, the midpoint potential would be E0' = -230 +/- 10 mV, thereb
227 which the exergonic oxidation of ferredoxin (midpoint potential, -453 mV) is used to drive the unfavo
228 utions were made to determine the effects on midpoint potential, activity, and EPR spectral propertie
229 nt negates the ability of TZDs to affect the midpoint potential, suggesting a model of drug binding i
230 tory action: the negative shift in heme c(n) midpoint potential, the increased amplitude of light-ind
231 he hemes display a large difference in redox midpoint potentials (DeltaEm_b), which in several protei
232 onic absorbance and EPR, this method defines midpoint potentials (E(m)) at pH 7.0 of approximately +2
233 lectron redox couples in Yap1-RD, with redox midpoint potentials (E(m)) of -155 and -330 mV, respecti
236 g cells into two systems with characteristic midpoint potentials and kinetic behaviors explains prior
238 N338T mutation shifted the first and second midpoint potentials for the FAD from +47 and -30 mV for
239 en estimated to be -0.6 V from the values of midpoint potentials measured with SAM bound to the clust
240 The insertions result in indicators with midpoint potentials of -229 to -246 mV and are thus bett
242 revealed reversible redox peaks with average midpoint potentials of 80 +/- 5 mV and 72 +/- 5 mV vs. A
243 POR yielded two pairs of redox peaks with midpoint potentials of 90 +/- 5 mV and -300 +/- 10 mV, r
245 ct with thermodynamic considerations, as the midpoint potentials of NAD(P)H do not suffice to support
248 c voltammetry was used to determine that the midpoint potentials of the two hemes in cytochrome c(4)
254 occur on the [4Fe-4S]H subcluster at similar midpoint-potentials (-375 vs -418 mV); the protonation e
257 ppearance of membrane blebs at the poles and midpoint, prior to the formation of enlarged round cells
259 nctions preferentially occur near nucleosome midpoints rather than in internucleosomal linker regions
261 tains a redox-active [4Fe-4S] cluster with a midpoint redox potential (E(m)) of -390 +/- 23 mV (pH 8.
262 bound close to oxidized bH, we calculated a midpoint redox potential (Em) of approximately 90 mV for
265 capture key properties of CcO, including the midpoint redox potentials of the metal centers and the e
270 .S(gamma) hydrogen bonds as reflected by the midpoint reduction potential, providing direct evidence
271 he mutant Dap1pY138F, as well as equilibrium midpoint reduction potentials of the Fe(III)/Fe(II) coup
272 nal change and effects a major change in the midpoint reduction potentials of the flavin redox couple
273 ial calmodulin-dependent perturbation in the midpoint reduction potentials of the redox couples of bo
274 ium of their FMN subdomains; (ii) the flavin midpoint reduction potentials; and (iii) the kinetics of
275 y switched to reach equilibrium at a similar midpoint regardless of winter habitat or diet suggesting
276 mark their cell division sites at their cell midpoint so that daughter cells are roughly equivalent i
277 ns in apo-Fet3p unfold sequentially [thermal midpoint (T(m)) of 45 degrees C, 62 degrees C, and 72 de
278 which show a large increase in their thermal midpoints (T(m) 40-43 degrees C) for a DeltaT(m) of 16-1
279 nd fibrinogen demonstrated higher transition midpoints (T(m)s) in concentrated rather than in dilute
280 r melting intermediate I(2) had a transition midpoint temperature (T(m)) of 61 degrees C and a CD spe
283 se and xyloglucan on the apparent transition midpoint temperature of the reduced, catalytically activ
284 nown to inhibit Hsf1 activation, lowered the midpoint temperature of trimerization and reduced cooper
285 orresponding to the approximate denaturation midpoint, the combined data are well fit by a combinatio
286 ration of the negative regulator at the cell midpoint, the greatest distance from both cell poles.
288 e allows quick calculation of the transition midpoint; the difference in the temperature of this midp
289 GC) separations by use of a microfabricated midpoint thermal modulator (muTM) are demonstrated, and
290 ed on calculation of a broad distribution of midpoint thermal-transition temperatures measured by the
291 FHbp variant, which increased the transition midpoint (Tm) for the N-terminal domain by 8 and 12 degr
292 DNA translocase that localizes to the septal midpoint to mediate chromosome translocation and membran
293 molecular sensing systems with a transition midpoint tunable with 0.1 pH units precision and with a
294 other rod-shaped bacteria select their cell midpoint using such a negatively acting morphogen gradie
297 wo component Boltzmann functions shift their midpoint voltages (Vh) in opposite directions during tre
299 The mean (SD) of the directly localized PPN midpoints was 6.4 mm (0.5) lateral, 3.5 mm (1.0) posteri
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