ライフサイエンスコーパス: milieu of

1 ncy-associated shifts in the transcriptional milieu of a cell may impact HML-2 activity.

2 These findings indicate that the cytokine milieu of a tissue can dramatically influence the develo

3 and to incorporate new neural cells into the milieu of a traumatic spinal cord injury.

4 ory effect of an unstable tissue oxygenation milieu of a tumor is likely to contribute to treatment r

5 nduced transcription in vitro in the complex milieu of a whole cell extract.

6 ting that PVs can influence the inflammatory milieu of adjacent airways.

7 Thus, the proinflammatory milieu of advanced atherosclerotic lesions may be promot

8 lates the leukocyte infiltrates and cytokine milieu of advanced human tumors.

9 nosaccharides available in the extracellular milieu of Agrobacterium tumefaciens can be transported i

10 esent findings demonstrate that the internal milieu of an animal can modify ingestion analgesia, and

11 ions modified to reflect the intrasinusoidal milieu of arginine (RPMI-1640 media with 10 or 100 micro

12 es of RNA may contribute to the inflammatory milieu of arteriosclerosis.

13 h micromolar dissociation constant (Kd) in a milieu of bacterial proteins with minimal sample prepara

14 Platelet-rich plasma (PRP) is a milieu of bioactive factors, including platelet derived

15 metastasis by modulating the local chemokine milieu of cancer cells in the TME.

16 For a long time, the external milieu of cancer cells was considered to be of secondary

17 and organellar dynamics within the cellular milieu of cardiomyocytes.

18 xpressed and purified from the extracellular milieu of cells as an SDS-soluble, nonaggregated protein

19 infectivity of sporozoites delivered into a milieu of changes induced by cutaneous hypersensitivity.

20 While the focus here is on the extracellular milieu of CHO cell cultures, this methodology is general

21 ediated liver regenerative response within a milieu of chronic inflammation links partial hepatectomy

22 The milieu of chronic kidney disease has associated factors

23 al features of the WT grafts immersed in the milieu of circadian malfunction were normal and absent o

24 compartments in which they occur, and in the milieu of competing proteins.

25 vely, these data indicate that TB provides a milieu of continuous cellular activation and irregularit

26 lators are tuned to optimize the hemodynamic milieu of critically ill patients.

27 olarization of macrophages is regulated by a milieu of cues in the local tissue microenvironment.

28 On inhabitation of the extracellular milieu of cultured cells by infective trypomastigotes, t

29 s (BMSCs), inhibits the production in the BM milieu of cytokines (interleukin-6 [IL-6], vascular endo

30 r subsets is controlled in large part by the milieu of cytokines present during their initial encount

31 l deposition within the disordered metabolic milieu of developing atherosclerotic plaque.

32 The brain is composed of a highly complex milieu of different cell types and few methods exist tha

33 nervous system and play complex roles in the milieu of diseases including the primary diseases of mye

34 Here, we characterized the immunological milieu of dystrophic muscle in mdx mice, a model of DMD,

35 ould be individualized to address the unique milieu of each implementation setting.

36 Thus, our study suggests that ligand in the milieu of EGFRvIII-expressing GBM cells is likely to inf

37 se toremifene prevented prostate cancer in a milieu of elevated blood free testosterone levels with n

38 tory cells including mast cells (MCs), and a milieu of enriched cytokines.

39 mune responses are regulated by the specific milieu of environmental factors, cytokines, and other si

40 utions are obfuscated by the complex in vivo milieu of factor redundancy and indirect effects.

41 maturation of naive human B cells within the milieu of germinal centers.

42 proteins to the surface and/or extracellular milieu of Gram-negative bacteria, are members of a large

43 tors generated within the local inflammatory milieu of hALX mice showed diminished ability to activat

44 To determine definitively the intracellular milieu of HGPRT in these pathogens, polyclonal antiserum

45 um (ER) stress both in the complex metabolic milieu of high-fat feeding as well as in the setting of

46 ich their presence in the microenvironmental milieu of high-risk breast tissue could play a determini

47 Biofilm formation occurs within a complex milieu of host factors and other members of the human mi

48 asitize, where they must sort through a rich milieu of host proteins and nucleic acids to gather toge

49 ally bind to amyloid deposits in the complex milieu of human brain or whether amyloid binding was ove

50 rage of signals present in the extracellular milieu of human immunodeficiency virus-infiltrated brain

51 se-dependent reduction of hypertrophy in the milieu of hyperglycemic culture media.

52 RANKL and OPG production in a cytokine-rich milieu of inflamed joints.

53 hostile extrinsic environment composed of a milieu of inhibitory factors.

54 transported over a long range in the aqueous milieu of interstitial spaces.

55 small group of self-proteins among the total milieu of intracellular self-proteins.

56 exerts its antioxidant effect in the aqueous milieu of LDL.

57 rant AR re-activation and CRPC growth in the milieu of low androgen.

58 mportance of FRCs in shaping the suppressive milieu of lymphoid organs during homeostasis.

59 at reside and multiply within the hydrolytic milieu of mammalian macrophage phago-lysosomes.

60 se may be due to differences in the cellular milieu of melanocytes and may have implications for norm

61 eothermal fields would resemble the internal milieu of modern cells.

62 We conclude that in a complex milieu of multiple CXC chemokines, CXCR1 functions as th

63 trafficking; (d) oxidative stress; and (e) a milieu of muscle cellular aging in which these changes o

64 r potential to emulate the electromechanical milieu of native tissues or conform well with the curved

65 sis and quantitation of apoptosis within the milieu of necrosis are analytical challenges.

66 Here we show that in the milieu of negative selection on physiological self class

67 ype 1 diabetes, in the diabetes-predisposing milieu of NOD mice in the absence of the endogenous clas

68 can target specific RNAs amidst the cellular milieu of non-target RNAs.

69 diffusing rapidly through the extracellular milieu of nonexpressing cells.

70 to 7.0, whereas the intra- and extracellular milieu of normal cells is 7.4.

71 nd secreted factors promote the inflammatory milieu of obesity, but the transcriptional pathways that

72 an the endocrine, adipokine, or inflammatory milieu of obesity.

73 of the molecular, cellular and extracellular milieu of pancreatic cancer, and discuss them in the con

74 in illuminating a key element of the immune milieu of pancreatic cancer.

75 Yet, how the milieu of pancreatic progenitor cells, including exposur

76 and posttreatment samples, we show a complex milieu of parasites, including variants likely up-select

77 ulmonary microenvironment contains a complex milieu of pattern recognition molecules of the innate im

78 T cells probe a diverse milieu of peptides presented by molecules of the major h

79 DeltaA1-488 bound platelets in the milieu of plasma.

80 parasitemia might be impaired by the type 2 milieu of preexisting helminth infection.

81 critical period in adolescence the hormonal milieu of pregnancy affects the developmental fate of a

82 itor, the composition of their intracellular milieu of proteins changes to appropriately guide their

83 t step we addressed aptamer stability in the milieu of proteins present in these environments.

84 ors may contribute to the overall angiogenic milieu of RCC.

85 sphate crystals are more likely to form in a milieu of reduced PPi concentration.

86 Metazoan genes are embedded in a rich milieu of regulatory information that often includes mul

87 There is accumulating evidence that the milieu of repeat elements and other non-genic sequence f

88 , its behavior must be shaped by the complex milieu of sensory stimuli it detects, its previous exper

89 echanisms by which axons convert the complex milieu of signaling molecules into retrograde signals ar

90 igration and to the highly immunosuppressive milieu of solid tumors.

91 hniques is that we can incorporate the whole milieu of soluble factors produced by cells in situ into

92 ile both are exposed to the same circulating milieu of soluble factors.

93 Chronic HCV infection appears to disrupt the milieu of soluble inflammatory mediators even after vira

94 ndage and the left atrial body may produce a milieu of stagnant blood flow within the appendage and b

95 amic nature of the extracellular biochemical milieu of stem cell microenvironments that regulate plur

96 In a milieu of sustained plasma P4 levels, these reciprocal c

97 enhancers, with a typical gene embedded in a milieu of tens of enhancers.

98 abolized, as well as the prevailing hormonal milieu of that tissue.

99 l mechanisms readily overcome the inhibitory milieu of the adult injured spinal cord to extend many a

100 ginate from the environment but adapt to the milieu of the airway of the cystic fibrosis patient and

101 a major role in the immune and inflammatory milieu of the airway.

102 udied the effects of the highly inflammatory milieu of the atherosclerotic plaque on IGF-1 signaling

103 The interstitial milieu of the brain is buffered to an average pH of 7.3,

104 h that 'senses' changes in the intracellular milieu of the cardiac myocyte and responds by preferenti

105 However, in the milieu of the cell, the energy landscape can be modulate

106 Among the molecular milieu of the cell, the membrane bilayer stands out as a

107 elected to function optimally in the crowded milieu of the cell.

108 cks them from responding to the trans-acting milieu of the cell.

109 lar composition, organization, and molecular milieu of the cellular infiltrates in muscle in juvenile

110 steine 474 of OCT2 is exposed to the aqueous milieu of the cleft and contributes to forming a pathway

111 The milieu of the CNS during HIV infection is extraordinaril

112 data demonstrate that the altered metabolic milieu of the diabetic pregnancy causes permanent defect

113 s a safe, noninvasive method of sampling the milieu of the distal lung and is sufficiently sensitive

114 When maintained in the normal ionic milieu of the ear, many bundles oscillated spontaneously

115 -induced conformational change in the acidic milieu of the endosome, resulting in fusion of viral and

116 How the genetic milieu of the epithelial compartment influences tumor an

117 proinflammatory cytokines released into the milieu of the epithelium in patients with Crohn's diseas

118 suggesting that a decline in the estrogenic milieu of the females could be a factor in accelerating

119 a complex phenotypic differentiation by the milieu of the germinal center.

120 Within the milieu of the gut, this represents a novel mechanism by

121 d to be a hallmark of T cells exposed to the milieu of the HBV-infected liver in patients with active

122 ic substrates such as p130Cas in the complex milieu of the host cell has not been fully elucidated.

123 e in serum and multiply in the iron-limiting milieu of the host vertebrate.

124 T cells recently activated by the antigenic milieu of the host, with negligible numbers of residual

125 ctions and is influenced by the inflammatory milieu of the host.

126 thesis that this cytokine was present in the milieu of the inflamed joint, and that it contributed to

127 ly-stage neurons can overcome the inhibitory milieu of the injured adult spinal cord to mount remarka

128 role in the maintenance of the unique ionic milieu of the inner ear fluid.

129 sessing target engagement within the complex milieu of the intracellular environment.

130 their activities respond to a change in the milieu of the intracellular transport pathway.

131 ffector phase of arthritis by regulating the milieu of the joint and serum, and by inducing apoptosis

132 The normal milieu of the kidney includes hypoxia, large osmotic flu

133 ars of Saccharomyces cerevisiae in the cell milieu of the latter despite the facts that the protein

134 eta appears to be localized within the lipid milieu of the lipoprotein particle and not associated wi

135 We propose that the metabolic milieu of the lung, and potentially other tissues, is an

136 acetate to mimic the decidualizing steroidal milieu of the luteal phase and early pregnancy.

137 ggest that IL-7 may function to regulate the milieu of the microenvironment by modulating IL-6 secret

138 to neurons and astrocytes in the post-injury milieu of the neonatal brain injured by HI.

139 ng this we need to consider the multisensory milieu of the newborn infant.

140 by this region were essential in the complex milieu of the nucleus.

141 transfect other cells and that the metabolic milieu of the parental cell decides the quality of exoso

142 mine whether the vector would survive in the milieu of the peritoneal cavity, the authors examined th

143 In this study, the normal milieu of the primate spinal cord was disturbed by multi

144 between donor organ quality and the biologic milieu of the recipient.

145 nd display an alteration in the inflammatory milieu of the serum and cerebrospinal fluid.

146 a gatekeeping enzyme regulating the hormonal milieu of the SG.

147 the external environment and/or the internal milieu of the skin can lead to pathological conditions s

148 ery while targeting the immunologically rich milieu of the skin.

149 environmental stresses including the acidic milieu of the stomach and the toxic effects of bile in t

150 +]o, potentially regulated by changes in the milieu of the synaptic cleft during neural activity.

151 ell activation within the highly immunogenic milieu of the transplanted tissue.

152 suppressor mutations can modulate the immune milieu of the tumor microenvironment, and they offer spe

153 While folates are absorbed in the acidic milieu of the upper small intestine, the underlying abso

154 or' molecules into the cytoplasm or cellular milieu of their hosts to facilitate colonization.

155 Soluble factors in the biochemical milieu of these wounds are sufficient to activate the in

156 inal ganglion cells (RGCs) require a complex milieu of trophic factors to enhance cell survival and a

157 rately acidic pH similar to the pericellular milieu of tumors.

158 eriments were carried out in three different milieus of varying fluidity [mixed micelles, 1-palmitoyl

159 We demonstrate that this milieu of vascular growth factors is altered in streptoz

160 When added as liposomes to the milieus of water-soluble molecules to be delivered throu

161 t to the alcohol content (13.5 vol%), acidic milieu of wine and other ingredients present during the