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1  by forced expression of a deacetylated CTTN mimetic.
2  of inhibitor has emerged that lacks the RGD-mimetic.
3  of superoxide dismutase 1 (SOD1) or an SOD1 mimetic.
4 th low oxygen and cobalt chloride, a hypoxia mimetic.
5 ting concentrations of agonist and G protein mimetic.
6 istate 13-acetate (PMA), which acts as a DAG mimetic.
7  presence of a superoxide dismutase/catalase mimetic.
8 haride capsule, hydrolyzed a peptide antigen mimetic.
9 an help guide the design of a simpler Klotho mimetic.
10 g cells from the lethal effects of UV and UV mimetics.
11  5-nonyloxytryptamine and vinorelbine as PSA mimetics.
12 E1 efficiently hydrolyzes acyl-CoA substrate mimetics.
13 er normal degradation when expressed as SUMO mimetics.
14 c restriction and act as caloric restriction mimetics.
15 ind fatty acids are considered as fatty acid mimetics.
16 red resistance to BCL-2 family-targeting BH3 mimetics.
17                                While Dyp (GS mimetic 15) has only minimal influence on the biological
18 -Pro2 eradicates the biological activity (GS mimetic 16).
19 ers of different sizes were substituted with mimetic 2.
20                    In an inhibition assay, a mimetic (2, mimHNK-1) of the natural HNK-1 epitope block
21  but not in Sirt3(-/-) mice, whereas an SOD2 mimetic, (2-[2,2,6,6-tetramethylpiperidin-1-oxyl-4-ylami
22                                This antibody-mimetic 2D material holds great potential toward the blo
23  for self-assembly of highly stable membrane-mimetic 2D nanomaterials and exhibit protein-like functi
24 e, free-standing and self-repairing membrane-mimetic 2D nanomaterials through a facile crystallizatio
25 e anticipate that this new class of membrane-mimetic 2D nanomaterials will provide a robust matrix fo
26  antidiabetic drug metformin or with the AMP mimetic 5-aminoimidazole-4-carboxamide ribonucleotide in
27          Notably, sole treatment with a BDNF mimetic, 7,8-dihydroxyflavone hydrate, significantly res
28 y the small molecule Bcl-2 homology domain 3 mimetic, A-1331852, or Bcl-xL-specific small interfering
29 h host neuronal proteins, and these anti-GAS mimetic Abs are associated with autoimmune diseases of t
30 s fludarabine and the BCL2 homology domain 3 mimetic ABT-737.
31 % bromine content has shown novel peroxidase mimetic activity toward 3,3',5,5'-tetramethylbenzidine (
32 ium-gold nanozyme shows excellent peroxidase mimetic activity with O-phenylenediamine in the presence
33 of selected organophosphates on their enzyme mimetic activity.
34  these molecular events, a reconstructed ivy-mimetic adhesive composite was developed by integrating
35 pressed after treatment with the adiponectin mimetic AdipoRon, which were associated with increased i
36                                     Cofactor-mimetic aerobic oxidation has conceptually merged with c
37 d highlight the therapeutic potential of Shh mimetics against CNS complications associated with HIV i
38 eltaN-expressing mice and exposed to hypoxia-mimetic agent cobalt chloride exhibited less apoptosis a
39  inhibited by Tempol (a superoxide dismutase-mimetic agent) and by glyburide (an inhibitor of potassi
40 o the design of the first serum stable TSP-1 mimetic agonist peptide able to trigger selective progra
41 mately led us to engineer a minimized hINSL5 mimetic agonist that retains native hINSL5-like RXFP4 af
42           Addition of the C-terminal peptide mimetic alphaCT1, a selective inhibitor of Cx43 channels
43                             Sobetirome, a TH mimetic, also blunted bleomycin-induced lung fibrosis.
44 uced by SFA palmitate, we found that the AMP-mimetic AMPK activator 5-aminoimidazole-4-carboxamide-1-
45 asitism risk is challenging: cuckoo eggs are mimetic and adult cuckoos are secretive and resemble haw
46  find that bidirectional transitions between mimetic and cryptic coloration are unexpectedly frequent
47 rtib, a styryl-benzyl sulfone, acts as a RAS-mimetic and interacts with the RBDs of RAF kinases, resu
48 l hydrophobic peptides that act as substrate mimetics and compete in the luciferase aggregation suppr
49 arrier proteins (ACPs) loaded with substrate mimetics and cross-linkers to visualize and trap interac
50 L, or Mcl-1 recapitulated the effects of BH3 mimetics and enhanced the effects of gamitrinib-TPP.
51                            In vivo, miR-193b mimetics and FAK inhibitor (PF-562271) each inhibited li
52                  We found that combining BH3 mimetics and gamitrinib-TPP blunted cellular proliferati
53 in diverse areas including catalysis, enzyme mimetics and material science.
54 ALL cultures were both more sensitive to BH3 mimetics and more uniform in their response than establi
55 ed to the development of calorie restriction mimetics and other pharmacological interventions capable
56 a novel in vivo screening platform for mucin mimetics and other strategies to treat diseases of the o
57  field of metallo-organic antifreeze protein mimetics and provides insight into the origins of ice-gr
58  hydrolytic activity of 18B7 against peptide mimetics and show that 18B7 is able to hydrolyze an olig
59 P1 and XIAP in MC38 and YAMC cells, and Smac-mimetics and TNF-related weak inducer of apoptosis incre
60 ccommodate the faster reacting water-soluble mimetics and to more closely duplicate in vivo condition
61 f the nNOS inhibitors developed are arginine mimetics and, therefore, suffer from poor bioavailabilit
62 ersonalized therapy with abatacept, a CTLA-4 mimetic, and inform genetic counseling.
63 rotein complexes by small molecules, peptide mimetics, and natural products.
64 ed sulfated polysaccharides, heparan sulfate mimetics, and occluding compounds.
65 s of the interaction of CsgB with a membrane-mimetic anionic surfactant as well as with lipopolysacch
66 id) of the natural ligands; however, the RGD-mimetic antagonists for alphaIIbbeta3 have been shown to
67                          Venetoclax is a BH3 mimetic approved for treating chronic lymphocytic leukem
68                 In summary, HDACi and a BDNF mimetic are sufficient to rescue retinal cell death and
69                                     As GLP-1 mimetics are administered systemically in humans, we eva
70                            Suitable membrane mimetics are crucial to the performance of structural an
71 tides (SAHPs) designed as apolipoprotein A-I mimetics are known to bind to class B scavenger receptor
72           Three reported dietary restriction mimetics are mainly effective across C. elegans strains,
73          Herein, the construction of a DNase-mimetic artificial enzyme (DMAE) for anti-biofilm applic
74  here will facilitate the generation of pArg mimetics as highly potent inhibitors of the enzymes that
75 , using JR-FL SOSIP.664, a native Env trimer mimetic, as a sorting probe to isolate monoclonal Abs (M
76 al of Affimers, a recent example of antibody mimetics, as suitable bioreceptors for the detection of
77   Here we design and synthesize oligomannose mimetics, based on the unique chemical structure of a re
78      Here we identified potent acetyl-lysine mimetic benzimidazolones TRIM24 bromodomain inhibitors.
79            In this study, we present a brain-mimetic biomaterial ECM platform for 3D culturing of pat
80          The crystal structure of one of the mimetics bound to a member of this bnAb family confirms
81 g films, solid-supported membranes, membrane-mimetic brushes).
82                      Detergents and membrane mimetics can solubilize membrane proteins but do not alw
83  can be circumvented with small-molecule CD4 mimetics (CD4mc) that are able to transition Env into th
84  both flow cytometry and mass cytometry in a mimetic cell mixture and human peripheral blood mononucl
85  snake species to demonstrate that shifts to mimetic coloration in nonvenomous snakes are highly corr
86             Recently, a large North American mimetic complex was described that included 65 species o
87 d mitochondrial activator of caspases (Smac)-mimetic compound LCL161 or recombinant TNF-like weak ind
88 well as the therapeutic potential of the SOD-mimetic compound M40403.
89   The consequences of the binding of the CD4-mimetic compound to the HIV-1 envelope glycoproteins dep
90  only when the virus was sensitized by a CD4-mimetic compound.
91                           Small-molecule CD4-mimetic compounds (CD4mc) bind gp120 and act as competit
92  of apoptosis (IAP) antagonists, called Smac mimetic compounds (SMCs), sensitize tumours to TNF-alpha
93 c factors that influence the activity of CD4-mimetic compounds can help to improve their potency and
94 dition to their direct antiviral effect, CD4-mimetic compounds dramatically enhance the HIV-1-neutral
95                           Small-molecule CD4-mimetic compounds engage the CD4-binding pocket on the g
96       Here we report that small-molecule CD4-mimetic compounds induce the CD4-bound conformation of E
97                           Small-molecule CD4-mimetic compounds inhibit HIV-1 infection by multiple me
98  Used as components of microbicides, the CD4-mimetic compounds might increase the protective efficacy
99             We found that small-molecule CD4-mimetic compounds sensitize HIV-1 to antibodies that can
100                       Here, we show that CD4-mimetic compounds sensitize primary HIV-1 to neutralizat
101 comprehensively surveyed the efficacy of BH3 mimetic compounds, identifying potent and specific MCL-1
102 h sensitivity to Bcl-2 inhibition by the BH3 mimetic compounds.
103  of their structural resemblance, fatty acid mimetics constitute a family of bioactive compounds show
104                            The 6-Helix-based mimetics could be used as a platform to study the molecu
105 uses axon degeneration and suggest that Bclw-mimetics could provide effective therapy to prevent CIPN
106                          Caloric restriction mimetics (CRMs) mimic the biochemical effects of nutrien
107 genic mouse models were generated: a phospho-mimetic cTnIS200D and a phospho-silenced cTnIS200A, each
108  repertoire of lipids versus bicelle bilayer mimetics currently employed in solid-state nuclear magne
109 reviously reported the discovery of a CXCL12-mimetic cyclic peptide (2) as a selective CXCR4 antagoni
110                 Here we describe an antibody mimetic, DARPin K27, which inhibits nucleotide exchange
111  both facilitate delivery of the heptaketide mimetic deep into the PT active site and anchor one end
112 that the anti-inflammatory effect of fasting-mimetic diets may be mediated, in part, through SIRT3-di
113 pment of soluble envelope glycoprotein (Env) mimetics displaying ordered trimeric symmetry has ushere
114 re characterized, particularly for the lipid mimetic dodecylphosphocholine.
115  (ROL; a PDE4 inhibitor) and Bt2cAMP (a cAMP mimetic) drive caspase-dependent resolution of neutrophi
116 properties of cAMP-elevating agents and cAMP-mimetic drugs.
117 CL1 and BCL-XL sensitizing PTCL cells to BH3 mimetic drugs.
118 ensive hitchhiking of linked variants on the mimetic dsx haplotype that occurred at the origin of mim
119 the redox status of the cell and has insulin mimetic effects.
120 olution NMR and EPR spectroscopy in membrane-mimetic environments, consists of a helix-turn-helix arc
121  synthetic superoxide dismutase and catalase mimetic EUK-134 also ablated the effects of hypoxia on B
122 uman-antibody transgenic animals with a lead mimetic evokes nAbs with specificities approaching those
123 ing forskolin or the glucagon-like peptide 1 mimetic Exendin-4, inhibits the shuttling of MondoA and
124 ylic-polyuridylic acid (poly A:U) is a dsRNA mimetic explored empirically in cancer immunotherapy a l
125                     We prepared the antibody mimetic Fab-PEG-Fab (FpFinfliximab) for direct intravitr
126 ical rationale to further evaluate this SMAC mimetic for BCP-ALL treatment.
127 d platinum nanoparticles (Pt NPs) as oxidase mimetics for effectively catalyzing the oxidation of 3,3
128 HT1B/1D agonist or cytostatic drug to act as mimetics for PSA to stimulate regeneration after injury
129 ith the small-molecule, superoxide dismutase mimetic (GC4419; 0.25 mumol/L) significantly mitigated t
130 knesses by coating them with synthetic mucin-mimetic glycopolymers.
131  vesicles (glycOMVs) decorated with pathogen-mimetic glycotopes.
132  the tiger-striped silvaniform clade, and co-mimetic H. melpomene nanna.
133           Crucially, CENP-A with acetylation-mimetic H4 was assembled specifically into centromeres e
134     However, previous studies using membrane mimetics have not identified any notable difference in t
135 ereas the filaments from the cMyBP-C phospho-mimetic hearts showed a strong tendency toward disorder.
136                  We engineered synthetic ECM-mimetic hydrogels with independent control over adhesive
137  pressing and in situ polymerization, "nacre-mimetic" hydroxyapatite/poly(methyl methacrylate) (PMMA)
138 is binding interaction using heparan sulfate mimetics, identify an important sulfate modification, an
139 tion, requiring a systematic approach to Env mimetic immunogen design and evaluation of elicited resp
140 fford a view of a polyketide "atom-replaced" mimetic in a NR-PKS active site that could prove general
141 y demonstrates the efficacy of a novel FGF21 mimetic in hamsters, but reveals attenuated effects in t
142 thened Agonist (SAG), a Sonic Hedgehog (Shh) mimetic in order to fortify blood brain barrier (BBB) an
143 rapeutic effectiveness of the thrombopoietin mimetics in ITP.
144 llographic application of "atom replacement" mimetics in which isoxazole rings linked by thioethers m
145    Nucleopeptides are promising nucleic acid mimetics in which the peptide backbone bears nucleobases
146                           Heparin or heparin mimetics including Roneparstat, a modified heparin in ph
147 rexpression of a Ser166-Mdm2 phosphorylation mimetic increased EC migration, increased Mdm2 to FoxO1
148 factor of cancer cell susceptibility to SMAC mimetic-induced necroptosis.
149 ase domain of human NEK1 in its apo- and ATP-mimetic inhibitor bound forms.
150  will discuss the discovery of these non-RGD-mimetic inhibitors and the progress that has been made i
151 ted that Arg-Gly-Asp (RGD)-containing ligand-mimetic inhibitors of integrins are unable to dissociate
152    The self-assembly of peptides and peptide mimetics into supramolecular polymers has been establish
153 tematically evaluates targets for fatty acid mimetics, investigates their common structural character
154                                 One of these mimetics is bound avidly by members of a family of oligo
155 chemical structure analysis and to produce a mimetic Kdo-lipid A domain AlmG substrate to that synthe
156 oduce excessive cytosolic levels of the GABA-mimetic l-proline which impairs GABA synthesis and gamma
157 tures that guide the self-assembly of physio-mimetic laminar cardiac tissues.
158 rehensive functional screen of a human miRNA mimetic library in a cell-based assay for invasion by th
159  which emerged from screening an alpha-helix mimetic library, stimulate the immune response, act by a
160  report several new classes of acetyl-lysine mimetic ligands ranging from mM to low micromolar affini
161 nteractions using native lipids and membrane mimetic liposomes and bicelles.
162 cordingly, the anchoring of GAD65 to exosome-mimetic liposomes strongly boosted antigen presentation
163 e W69A/S115W mutant bound to the CD4 peptide mimetic M48U1 and Fab of anti-cluster A antibody N60-i3
164 nogen by cross-linking of gp140 with the CD4-mimetic M64U1 elicited an earlier increase of binding an
165 pment of low-molecular-weight, synthetic BH3 mimetics ("magic bullets") to disrupt the protein-protei
166 -crystalline cubic phase (LCP) is a membrane-mimetic material useful for the stabilization and struct
167 that multi-regimen treatments including SMAC mimetics may be effective.
168 ults indicate that birinapant and other Smac mimetics may have efficacy in treating HBV infection and
169  previously described highly mobile membrane mimetic membrane in combination with a conventional lipi
170 ty analysis with both highly mobile membrane mimetic membranes and conventional lipid bilayer molecul
171 so, increased mass addition to Gram-positive mimetic membranes from AMP disruption corresponded with
172 guest encapsulation behavior in a new enzyme-mimetic metal-ligand host and provides the first observa
173 regimen containing Env cross-linked to a CD4-mimetic miniprotein (gp140-M64U1) in rhesus macaques.
174           On addition of Bcl-2 targeting BH3 mimetics, mito-primed cells undergo apoptosis in a rapid
175 on-haem iron was investigated in an in vitro mimetic model of the digestive tract using specific chem
176 activity and synthetic tractability with RGD-mimetic molecules, along with the issues relating to pha
177 atch up with the hosts with a newly acquired mimetic morph, host polymorphism should be maintained th
178          Moreover, overexpression of phospho-mimetic mutant stathmin S16D significantly rescued the d
179  Analyses with phospho-defective and phospho-mimetic mutants of FoxM1b identified a critical role of
180 aspartate (HD) domain (D311A), and a phospho-mimetic mutation (T592E), abrogated the inhibitory activ
181 re targets of DNA-PKcs and show that phospho-mimetic mutations at these residues significantly inhibi
182 and pre-active state and, in complex with Gs-mimetic nanobody, between more and less active ternary c
183  in the presence or absence of the G-protein mimetic nanobody.
184 racterize how PI(3,4,5)P3, CaM, and membrane mimetics (nanodisc) bind to Akt(PHD).
185 ight be of relevance for the action of GLP-1 mimetics now widely used in the treatment of diabetes.
186 les, called non-saccharide glycosaminoglycan mimetics (NSGMs), as direct allosteric plasmin inhibitor
187 of Cln1(-/-) mice with a thioesterase (Ppt1)-mimetic, NtBuHA, ameliorated this defect.
188 rdingly, the combination of THZ1 and the BH3 mimetic obatoclax improves lymphoma growth control in a
189 te whether the beneficial effects of a novel mimetic of FGF21 in the LD state are a consequence of in
190            Here, we study the structure of a mimetic of Martian water, magnesium perchlorate aqueous
191 the efficacy of birinapant, a small-molecule mimetic of the apoptotic regulator SMAC, against a diver
192 o and in vivo efficacy of SPX-101, a peptide mimetic of the natural regulation of ENaC activity by sh
193    We generated a membrane-permeable peptide mimetic of the PTPsigma wedge domain that binds to PTPsi
194  by a neuroprotective cell-permeable peptide mimetic of the region.
195 s of NagZ with the substrate, products and a mimetic of the transient oxocarbenium species, which wer
196                            A pharmacological mimetic of TIMP3 blocked the conversion of FAPs into adi
197 ance spectroscopy with (15)N-labeled peptide mimetics of cryptococcal polysaccharide antigen (Ag).
198  identify improved small molecule functional mimetics of H2-RLX with selective, full agonist or posit
199                                              Mimetics of natural structures represent useful tools fo
200 substituents function as peroxide-destroying mimetics of the antioxidant selenoenzyme glutathione per
201                    We constructed functional mimetics of the intracellular domain of a model GPCR, th
202 panel of substrates (both simple and complex mimetics of their natural substrates).
203 that Ad36E4ORF1 is not a typical sensitizer, mimetic, or secretagogue of insulin.
204 the origin of a species adapted to the local mimetic pattern and characterised by morphologically dis
205 fers from purifying selection acting on each mimetic pattern, indicates that predator knowledge, inte
206                                       A CD28 mimetic peptide (AB103; previously known as p2TA) that a
207 ession and administration of specific apoA-I mimetic peptide (D-4F) on tumour progression by using ma
208         Conversely, treatment with an ApoA-I mimetic peptide ameliorated the phenotypic, histopatholo
209  was developed, being the first one based on mimetic peptide and screen-printed carbon electrode, aim
210 ide proof of concept for the use of Cavbeta2 mimetic peptide as a novel therapeutic tool for the impr
211    Using these data we have designed a BCL-3 mimetic peptide based on a region of the ANK1 of BCL-3 t
212 onal antibody E06 or with apolipoprotein A-I mimetic peptide D-4F, capturing OxPAPC in atherosclerosi
213 inds the unmodified version of the PP2A-tail mimetic peptide DYFL compared to its tyrosine-phosphoryl
214                                  Delivery of mimetic peptide into a mouse model of diabetic cardiac d
215                               aCT1 is a Cx43 mimetic peptide that in preclinical studies accelerated
216 asis of this mechanism, we developed a novel mimetic peptide that, through targeting of Cavbeta2, cor
217 tion, we developed a small 5 amino acid apoE mimetic peptide(CN-105) that mimics the polar face of th
218 ped based on the immobilization of the PRF+1 mimetic peptide, as recognition biological element, on t
219 age of Cx43 HC function by TAT-Gap19, a Cx43 mimetic peptide, significantly upregulated the expressio
220 trophic factor (CNTF) small-molecule peptide mimetic, Peptide 021 (P021), rescued developmental delay
221 show how the self-assembly of short collagen-mimetic peptides (CMPs) can enable the fabrication of sy
222 equires association of two distinct collagen mimetic peptides (CMPs).
223 ly of two different building units: collagen-mimetic peptides and DNA origami.
224                   Short B7-2 dimer interface mimetic peptides bind diverse superantigens, prevent sup
225 in and a series of agonistic or antagonistic mimetic peptides free in solution.
226 ism by apolipoprotein A-I (apoA-I) and other mimetic peptides that form a belt around HDL.
227  and in vitro can be achieved using IKKgamma-mimetic peptides.
228 ificantly exceeding that of analogous mussel-mimetic peptides.
229  for suicidality, such as ebselen (a lithium mimetic), piracetam (a nootropic), chlorogenic acid (a p
230                        AS-1, the TIR/BB loop mimetic, plays a protective role in cardiac ischemia/rep
231 ehavioral and physical response to the dsRNA mimetic poly I:C is dependent on signaling via MyD88 whe
232 rats challenged with virus or with the viral mimetic polyinosinic:polycytidylic acid (poly I:C).
233 induced by maternal treatment with the viral mimetic polyriboinosinic-polyribocytidylic acid in middl
234 y, these catalytic nanomaterials with enzyme-mimetic properties have found new biomedical application
235     Using small molecule inhibitors, phospho-mimetic proteins, tamoxifen-sensitive and tamoxifen-resi
236 tern switches in multiple species across the mimetic radiation in Heliconius butterflies.
237                                         Smac-mimetics reduced levels of cIAP1 and XIAP in MC38 and YA
238 s indicates that sensitivity of cells to BH3 mimetics reflects the identity of the anti-apoptotic pro
239 vestigate the evolution of fangs, venom, and mimetic relationships in reef fishes from the tribe Nemo
240 ence via the formation of a diverse array of mimetic relationships that provide protective (Batesian
241     Furthermore a mutant DD with the phospho-mimetic residue Asp at this position is impaired in both
242              Critically, a claudin-5 peptide mimetic reverses the deleterious effects of alcohol on a
243          Overexpression of a phosphorylation mimetic (S226D) in young 3xTg mice strongly promotes APP
244                      Consistently, a phospho-mimetic S321D RIPK1 mutation limits TNF-induced death.
245 nd to the phospho-L-selectin tail or phospho-mimetic S364D L-selectin tail.
246                                  The phospho-mimetic S437D mutation stabilizes Acn and promotes basal
247 -deficient Ser999-to-Ala (S999A) and phospho-mimetic (S999D) mutations.
248 4-benzoxazepine backbone, an N-acetyl-lysine mimetic scaffold that led to the recent development of t
249   Our data unravel the organization of tmTNF-mimetic scTNF ligands capable of robustly activating TNF
250                            Here, an antibody-mimetic self-assembling peptoid nanosheet containing sur
251                     Birinapant, a novel SMAC mimetic, sensitized multiple HNSCC lines to cell death b
252 e cross-linking with a 3-kDa CD4 miniprotein mimetic, serving to block ligation of gp140 on CD4(+) T
253                       In summary, fatty acid mimetics share particularly favorable characteristics ju
254  numata Positive FDS imposed by predators on mimetic signals favors the fixation of the most abundant
255 nsitization by cotreatment with a miR-139-5p mimetic.Significance: The microRNA described in this stu
256                         Birinapant is a smac-mimetic (SM) in clinical trials for treating cancer.
257                        Administration of Shh mimetic, smoothened agonist (SAG) restored BBB integrity
258                                         Smac mimetics (SMs), a class of drugs that can promote tumor
259 -expression of either wild type or a phospho-mimetic stathmin mutant (4E) made defective in tubulin b
260 phospho-deficient [Su(H)(S269A)] and phospho-mimetic [Su(H)(S269D)] variants: the latter displayed re
261                           Similarly, phospho-mimetic substitutions in the DHBV CTD did not block the
262                                          BH3 mimetics such as ABT-263 induce apoptosis in a subset of
263 se findings suggest that combination of SMAC mimetics such as birinapant plus radiation may be partic
264                                           HS mimetics, such as PG545, have been developed as antitumo
265 CD4-Ig, a fusion of CD4-Ig with a small CCR5-mimetic sulfopeptide, binds avidly and cooperatively to
266           Metastatic cells cultured on osteo-mimetic surfaces coated with tenascin C exhibited enhanc
267 ty of a size-adaptable phospholipid membrane-mimetic system for solution NMR studies of membrane prot
268 commonly acknowledged as an optimal membrane mimetic system that provides control over size, composit
269 rotein-protein complex formation in membrane mimetic systems.
270                                         SMAC mimetics target cIAP1/2 for destruction, and consequentl
271 t signaling, which was abolished by the SOD1 mimetic, tempol.
272 om aflatoxin biosynthesis with a heptaketide mimetic tethered to a stably modified 4'-phosphopantethe
273                  Our analyses focused on BH3 mimetics that are broad acting (ABT263 and obatoclax) or
274 hat receptor-binding scFvs or small antibody mimetics that have no agonist activity on their own can
275 ligands consisting of two identical oxytocin-mimetics that induce a three order magnitude boost in G-
276 eering have led to the emergence of antibody mimetics that offer the high affinity and specificity as
277 he design of peptides, proteins, and peptide mimetics that predictably and efficiently reach the inte
278  EGF domains of L-selectin bound to a fucose mimetic; that is, a terminal mannose on an N-glycan atta
279 titative analytical technique by employing a mimetic tissue model previously shown to be applicable f
280 oll-like receptor 3 (TLR3) agonist used as a mimetic to study viral infection, has been shown to elic
281 Here, we describe the design of soluble GPCR mimetics to study the details of the interplay between G
282 to selectively evaluate the efficacy of SMAC mimetic treatment in CRC patients with caspase-8 deficie
283                                     MiR-148a-mimetic treatment in vivo suppressed tumor growth, reduc
284 chondria-derived activator of caspase (SMAC) mimetic treatment induced massive cell death and led to
285  we investigated the effectiveness of a BDNF-mimetic treatment with 7,8-dihydroxyflavone at alleviati
286 plasma (PRP) treated with the thromboxane A2 mimetic U46619, collagen and thrombin in presence/absenc
287              The clinical success of the BH3-mimetic venetoclax has generated increasing interest to
288  clinical success of the BCL-2-selective BH3-mimetic venetoclax in patients with poor prognosis chron
289 tion of BCL-2 has been achieved with the BH3 mimetic venetoclax, anti-tumor efficacy is limited by co
290 sequently sensitizing these cells to the BH3 mimetic venetoclax.
291 ary of oligopyridylamide based alpha-helical mimetics was designed to target the central alpha-helix
292 has recently been employed as an acetylation mimetic, we conducted a series of studies to evaluate it
293               Screening a library of 823 ATP mimetics, we identify both inhibitors and enhancers of C
294 HARI, in complex with a UbcH7 Ub thioester mimetic which reveals the molecular basis for the specif
295 I with the UbcH7 Ub thioester intermediate mimetic, which reveals that HHARI binds this E2 Ub in
296 ctions with monoclonal antibodies or peptide mimetics, which cause hypoalbuminemia, biliary loss of a
297 use it to develop a potent and simpler INSL5 mimetic with RXFP4 agonist activity.
298  proteins use synthetically produced heparin mimetics with defined structure or short heparin fragmen
299  analysis showed that the combination of BH3 mimetics with either SPHK1 inhibition or S1P receptor 2
300 g sites, and the development of carbohydrate mimetics with improved binding is therefore of interest.

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