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1 who had an alternative final diagnosis (CJD mimics).
2 to classify cases correctly (92% CJD, 2% CJD mimics).
3 o acute stroke units are diagnosed as stroke mimics.
4 hy along with its differential diagnoses and mimics.
5 well as towards designing synthetic adhesive mimics.
6 s as glycosyl phosphate and sugar nucleotide mimics.
7 ics, respectively, as compared with Zn-bound mimics.
8 ion for the design of artificial hydrogenase mimics.
9 ger (mean age (SD)) 49.1 (18.8) than medical mimic (63.5 years (16.7)) and stroke cases (71 years (15
13 phospholipid in the Salipro nanoparticle to mimic a realistic membrane environment while controlling
14 scences of the sunflower family, Asteraceae, mimic a solitary flower but are composed of multiple flo
15 get the "G site", and (2) an ABP designed to mimic a substrate molecule and have "H site" activity (G
16 e TLR7 agonists R-837 and R-848 were used to mimic a viral insult in the upper airways represented by
17 -long N-terminal extension that structurally mimics a dimer-dimer interface of these enzymes that are
24 capable of simultaneously delivering miR-34a mimic and targeting dysregulated polyamine metabolism in
25 ly to be female (63.3%) versus 49.7% medical mimics and 45.5% stroke, and younger (mean age (SD)) 49.
26 a also confirmed translation of miRNA target mimics and lncRNAs that produce trans-acting or phased s
31 at mirror the cellular effects of starvation mimics are considered promising therapeutics for common
32 cupric oxide nanorods (CuONRs) as peroxidase mimics are proposed for the development of a flow-throug
33 lled on tri-N-acetylglucosamine (NAG)3, a PG mimic, as well as PG isolated from various Gram (+) and
36 vidence is inconclusive: no model completely mimics Barrett's oesophagus in terms of the presence of
37 mimics the three predatory guilds avoid the mimics because of the additive influence of the various
41 s science, and engineering to understand and mimic biological systems that have the ability to autono
48 that YopO-mediated phosphorylation partially mimics calcium-dependent activation of gelsolin, potenti
49 t advanced stages of MARV or RAVV disease to mimic cases in which patients begin treatment for fulmin
50 ative diagnoses in more than half of the CJD mimic cases, and 10% had an immune-mediated encephalopat
51 ng), latent membrane protein 1 (LMP1) (which mimics CD40 signaling), and EBV-encoded nuclear antigen
52 ncluding multiple human liver cell types can mimic cell-cell interactions in specific types of DILI.
54 ting glutamate spillover in the NAcore would mimic cocaine-induced adaptations and potentiate cued re
55 alidation of minimal methylation classifier (MIMIC), combining CpG signature design from genome-wide
56 apatite-collagen (HC) composite material can mimic composition and ultra-structures of natural bone a
57 ore-microtubule interface, as mutations that mimic constitutive phosphorylation destabilized K fibers
58 xamined whether the EBV LMP2A protein, which mimics constitutively active B cell receptor signaling,
63 modified pikromycin (Pik) pentaketides that mimic early pathway engineering to probe the substrate t
64 thesis, multiple substitutions in the CTD to mimic either phosphorylation or dephosphorylation showed
65 by f-block metals, and that uranium can thus mimic elementary transition metal reactivity, which may
67 biology, researchers often use H2S donors to mimic enzymatic H2S synthesis or to provide increased H2
68 etically driven uniaxial ramp compression to mimic established embossing and imprinting processes, bu
69 been recapitulated in artificial nanochannel mimics, even though they lack certain molecular elements
72 osure of laboratory mice to carbon nanotubes mimics exposure to asbestos, from initial and chronic in
73 incorporation of bioactive factors to either mimic extracellular matrix or to deliver a payload to di
74 FpvAI (Kd = 240 pM) reveals that the pyocin mimics Fe-Pvd, inducing the same conformational changes
76 re we pattern linear fibronectin features to mimic fibrillar ECM and elucidate the mechanisms of cont
77 have screened a library of known human miRNA mimics for their effect on the replication of three flav
79 hat includes at least 140 different putative mimics from four arthropod orders including ants, wasps,
80 ith functional diseases that overlap with or mimic GERD can also be treated with neuromodulators (pri
82 diverse populations that also include stroke mimics, GPBB could find utility as a stand-alone marker
84 ructural types of natural products and their mimics have served as targets of opportunity in our labo
85 antiviral compounds.The lack of models that mimic hepatitis B virus (HBV) infection in a physiologic
86 studies demonstrate that metal nodes in MOFs mimic homogeneous catalysts not just functionally, but a
90 f the aortic valve, a phenotype that closely mimics human disease caused by NOTCH1 haploinsufficiency
91 tudying ZIKV disease because it more closely mimics human infection by mosquito bite than needle-base
94 that as tumor cell gene expression may often mimic immune and inflammatory infiltration, caution shou
97 bic and cationic moieties in these polymeric mimics improves non-covalent protein delivery, providing
100 er offering rapid access to complex alkaloid mimics in very few experimentally simple steps: (i) it a
101 Here we report that in Cln1(-/-) mice, which mimic INCL, reduced v-ATPase activity correlates with el
102 resulting in biallelic Igf2 expression that mimics increased levels seen with aging-induced LOI.
103 ls are hampered by a scarcity of models that mimic infection in a physiologically relevant, cellular
106 we describe a novel method based on intronic MiMIC insertions described in Nagarkar-Jaiswal et al. (2
107 n plants, the excess of several heavy metals mimics iron (Fe) deficiency-induced chlorosis, indicatin
109 the subcutaneous Matrigel plug assay, which mimics ischemic/inflammatory neovascularization, angioge
113 helf-life, and administered intravenously to mimic, leverage, and amplify physiological hemostatic me
115 8 from Ler were present in all of the hybrid mimic lines, whereas in the F6 small phenotype line, the
116 peptides and their effects on membranes that mimic lipid composition and biophysical properties of th
117 e perturbed genes in human melanoma cells to mimic loss-of-function mutations involved in resistance
119 embrane into an engineered material that can mimic, manipulate, and measure biophysical and biochemic
121 to phenylalanine, which is present in IGF1R, mimics many of these signalling and gene expression resp
124 anotubes with distinct lipid compositions to mimic membrane interactions with the fission machinery.
126 uminal cell differentiation, and mutant mice mimic miliaria and provide a possible animal model for i
129 ubsurface layer, comprised of a brain tissue mimic modified with neurotransmitters, and to determine
131 hat differentiates MS from CNS diseases that mimic MS clinically, pathophysiologically, and on imagin
133 h the microsomal fraction, whereas a phospho-mimic mutant, TH1-S31E, was distributed throughout the s
134 ikingly, deletion of the APC/C subunit Apc15 mimics mutations in this motif, revealing a shared funct
136 tegy for the design of synthetic agents that mimic natural glycosidases and address current problems
137 ial and temporal sophistication necessary to mimic natural microcircuit activity.SIGNIFICANCE STATEME
138 id water splitting-biosynthetic systems that mimic natural photosynthesis to achieve solar-to-chemica
140 ing mechanism in model materials designed to mimic natural systems, and explain the importance of the
141 between this same sterol and an exchangeable mimic of a high-melting phospholipid in liquid-ordered b
142 ble mimic of cholesterol and an exchangeable mimic of a low-melting phospholipid in liquid-disordered
143 port polyproline as a minimum (bio)synthetic mimic of antifreeze proteins that is accessible by solut
144 pulsive interactions between an exchangeable mimic of cholesterol and an exchangeable mimic of a low-
145 ed azetidine-2-carboxylic acid (Aze), a dual mimic of proline and alanine, is activated by both human
146 ings suggest that RaxX serves as a molecular mimic of PSY peptides to facilitate Xoo infection and th
147 erol and 10 +/- 2 cm/s in a 100% cholesterol mimic of the experimentally observed noncrystalline chol
148 nt Spinach aptamer, which is a synthetic RNA mimic of the Green Fluorescent Protein, from its split s
151 specific analysis of a recombinant, trimeric mimic of the native HIV-1 viral spike (BG505 SOSIP.664)
152 e, while the phosphonyl group is a versatile mimic of transition-states, intermediates, and primary m
155 SIP Env trimers are structural and antigenic mimics of the pre-fusion native, surface-presented Env,
157 tively synthesized, benzotriaepin-2-one turn mimics offer the potential to differentiate the respecti
158 rmore, AOX isoforms cannot be transformed to mimic one another by substituting the variable cysteine
159 Upon addition of a covalent inhibitor that mimics one of the reaction intermediates, there is an ov
160 Perturbation experiments with a miR-218-5p mimic or inhibitor demonstrated a protective role of miR
167 nown to host fermionic excitations which can mimic physics usually found in ultrarelativistic quantum
169 oped a novel animal model of HTG-AP that can mimic physiological, histological, clinical features of
172 and utrophin double mutant (mdx-dm) mice to mimic pre-pubertal nadir androgen condition resulted in
173 (CKII-acidic, LXCXE, E2F(TD) -like and LXCXE-mimic) predicted to interact with the cell cycle and dif
174 etal muscle, we show that TDP-43 acetylation-mimics promote TDP-43 phosphorylation and ubiquitination
175 ions and enable sharp pH changes in order to mimic properly IgGs Fc domain/FcRn receptor interaction.
176 A comprehensive study of this simple enzyme mimic provides insight into analogous behavior in biophy
177 t optimized an ARPE-19 cell culture model to mimic PVR by defining cell density, growth factors, and
179 manipulating pCO2 at the ecosystem level to mimic realistic fluctuations that occur on a number of d
180 the oxidase activity of Cu- and Fe-bound HCO mimics, respectively, as compared with Zn-bound mimics.
181 ibition of miR172 activity by a miRNA target mimic resulted in compact spikes and transition from glu
182 any of these metabolic conditions clinically mimic rheumatologic conditions owing to non-specific art
185 ditional cysteine tRNA with an 8/4 structure mimics selenocysteine tRNA and may function as opal supp
186 f microfluidic channels allows automation to mimic sequential analytical steps in benchtop environmen
188 Our data demonstrate that miR-34a synthetic mimics significantly enhance the anti-tumor activity of
190 actors through microfluidic experiments that mimic some of the confinement features of pore-scale geo
191 sly binding enzyme and substrate, emicizumab mimics some part of the function exerted by the original
192 ls of senescence targeting H3K9me3 or p53 to mimic spontaneous escape from the arrested condition, we
193 diagnosis and distinguish recrudescence from mimics, such as transient ischemic attacks, migraine, To
194 re up-regulated in the F1 hybrids and hybrid mimics, suggesting that increased auxin biosynthesis and
196 ay a behavioral and physiologic profile that mimics symptoms of depression in the clinical population
200 droxy-TEMPO (TEMPOL), a superoxide dismutase mimic that reacts with superoxide, rescued the growth of
201 paring valienyl ethers to serve as glycoside mimics that are capable of allylic rather than oxocarben
202 architectures, are Nature-inspired synthetic mimics that expose alpha/beta and alpha+beta protein cla
203 ic-based scaffold whose architecture closely mimics that of cuttlebone -a structural biomaterial whos
204 free virus-like particle (VLP) vaccines that mimic the "empty" capsids (ECs) normally produced in vir
207 ry1 is biologically hyperactive and seems to mimic the ATP-bound state of cry1, but the reason for th
208 ith longitudinal liquid-filled channels that mimic the basic features of natural stems and branches.
210 mensional in vitro cell model system as they mimic the complex tumor microenvironment and thus have c
213 ecapitulate spontaneous seizure activity and mimic the convulsive behavioural movements observed in D
214 IKV) outbreak, brain organoids engineered to mimic the developing human fetal brain have been employe
215 SIL peptides due to their ability to better mimic the digestion of human-derived proteins and mitiga
216 y was to create engineered environments that mimic the earliest known features of CAVD and apply this
217 ne "feed frame table," which was designed to mimic the full process from a NIR measurement perspectiv
218 ch convert energy into movement, are able to mimic the function of these amazing natural systems and
220 the design of immunogens that antigenically mimic the HIV envelope glycoprotein (Env), such as the s
226 s for the treatment of tissue defects should mimic the mechanical properties of the native tissue of
228 140, has also been made as a soluble form to mimic the native Env present on the virion surface.
229 Here, we demonstrate that it is possible to mimic the natural catalytic cycle of CYP101Fe(3+) by usi
230 ssay involving membrane components would (1) mimic the natural membrane environment, (2) be amenable
233 ed world, yet facile preclinical models that mimic the natural stages of CRC progression are lacking.
234 n, CMMPs act as 'synthetic stem cells' which mimic the paracrine and biointerfacing activities of nat
236 ification profiles were imposed, in order to mimic the pH normally obtained in southern-type and nort
237 ena, surrogate fly ashes were synthesized to mimic the presence of their major mineral components, in
238 are numerous reports in the literature that mimic the sample preparation procedure within a lab-on-a
239 because many recently developed mouse models mimic the severe neurological complications that occur i
240 jection of ATP into a peripheral nerve might mimic the stimulatory effect of nerve injury on the rege
242 ant HIV-1 envelope glycoprotein trimers that mimic the structure of the virion-associated spike, whic
243 the novel N9 protein appears to functionally mimic the substitutions that are found in the 2nd SIA-bi
245 The UL144 structure was predicted to closely mimic the surface of HVEM, and we also found that both H
246 ering multiple adjuvants at the same time to mimic the synergistic immune-stimulation of pathogens, w
247 We set out to take a different approach and mimic the synthesis of phospholipids using abiotic but h
251 ally pave the way for hardware that directly mimics the computational units of Bayesian inference.
253 itation of a "dirty" mouse model that better mimics the diverse infectious history that is typical of
254 plex reveals that the single domain antibody mimics the effect of binding of HIV integrase to LEDGF w
256 Kb/K2 cause Bartter syndrome, a disease that mimics the effects of the loop diuretic furosemide, ClC-
257 ic stimulation (tES) with a time course that mimics the endogenous activity of its target is capable
258 ribe a fully defined synthetic hydrogel that mimics the extracellular matrix to support in vitro grow
264 a time to form the potential landscape that mimics the ionic potential of atoms in natural materials
266 3-deficient osteoclasts, and RhoA inhibition mimics the osteoclast hyperactivation resulting from Gna
267 lamide, polyhydroxamicalkanoate (PHA), which mimics the performance of the acetylcholinesterase (AChE
268 computational fly photoreceptor model, which mimics the real phototransduction processes, has elucida
269 at, when wrapped around a metallic cylinder, mimics the scattering from a predefined, arbitrarily-sha
270 K4, a synthetic triacylated lipopeptide that mimics the structural moieties of its natural Gram negat
271 at despite the predominance of less defended mimics the three predatory guilds avoid the mimics becau
274 analyses of these plants suggests that SVP2 mimics the well-documented abscisic acid (ABA) effect on
276 cereal (Poaceae) families, but peptides that mimic their trypsin-inhibitory loops exist in sunflowers
277 veloped a stochastic simulation that exactly mimics these experiments, while imposing the 1:1 constra
278 develop in vitro release tests which better mimic this environment and cause drug release by the rel
279 al advocacy for their infant's best interest mimics this variability as requests for resuscitation, n
280 iple-grain, collective dynamic features that mimic those either observed or predicted in molecular-sc
282 tin architecture and gene expression closely mimic those of deleting the fetal globin repressor BCL11
283 mptoms of Lassa fever can be nonspecific and mimic those of other endemic infections, especially earl
286 oited beta-lactones as putative mycolic acid mimics to block serine hydrolases involved in their bios
287 diverse range of natural products and their mimics to create, explore, and solve a variety of proble
289 successfully indicated the acid regions of a mimic tumor from the basic region in a gelatin-based pha
291 and CFD circulation models were designed to mimic tumor progression by escalating flow complexity an
292 high-affinity recognition of the viral MHC-I mimic UL18 and a docking strategy that relies on contact
295 pha-hydroxypregnanolone, while mixtures that mimic wastewater and river water composition affected em
298 ituted glycines represent a class of peptide mimics with great potential in areas ranging from medici
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