ライフサイエンスコーパス: mimic of

1 asurements have been made using exchangeable mimics of 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholi

2 uplings in protonated and ionized structural mimics of 2 to determine how well theoretical prediction

3 ro-4-methylbenzimidazole nucleoside (2) as a mimic of 8-oxo-dA.

4 Here, we present an artificial mimic of a controllable host system that forms via self-

5 k of sequence homology, CDCA is a structural mimic of a functional beta-carbonic anhydrase dimer, wit

6 inuation of a previous study, a spin-labeled mimic of a glycan acceptor ligand is used to identify ad

7 between this same sterol and an exchangeable mimic of a high-melting phospholipid in liquid-ordered b

8 oteins in a second mechanism by which the WS mimic of a Legionella environmental niche can reverse vi

9 ble mimic of cholesterol and an exchangeable mimic of a low-melting phospholipid in liquid-disordered

10 Equilibrium simulations of a mimic of a phosphorylated R domain showed that it exhibi

11 e entire complex can be seen as a reasonable mimic of a phosphyl transfer transition state where the

12 e that allowed synthesis of a stable peptide mimic of a portion of the RSV fusion protein.

13 on gold a positively charged metallopeptide mimic of a section of the gp41 coiled coil containing a

14 We designed mimics of a key alpha-helical domain at the interface of

15 have higher affinity for inhibitors that are mimics of a late dissociative transition state.

16 e mechanisms using antisense oligonucleotide mimics of a pause RNA hairpin from the leader region of

17 was applied to histone proteins to install a mimic of acetylated lysine (KAc, an epigenetic marker).

18 COR is a structural mimic of active jasmonic acid (JA) conjugates.

19 mucillin-A (DADMe-ImmA) are transition state mimics of adenosine with geometric and electrostatic fea

20 emerges at the injury site fashions a close mimic of adult form.

21 an AEf-bound core, we designed a structural mimic of AEf-bound core protein, the V124W mutant.

22 ngenital cataract mutation, and the latter a mimic of age-related oxidative damage.

23 emerged as proteolytically stable structural mimics of alpha-helices.

24 out the backbone, are emerging as structural mimics of alpha-helix-forming conventional peptides (com

25 roach to lipophilicity determination using a mimic of an alkyl alcohol with compound partitioning qua

26 N-end rule adaptor, ClpS, bound to a peptide mimic of an N-end rule substrate.

27 port polyproline as a minimum (bio)synthetic mimic of antifreeze proteins that is accessible by solut

28 field of synthetic macromolecular (polymer) mimics of antifreeze proteins.

29 Synthetic Mimics of Antimicrobial Peptides (SMAMPs) imitate natura

30 One class of these synthetic mimics of antimicrobial peptides (SMAMPs) is being devel

31 A new series of aryl-based synthetic mimics of antimicrobial peptides (SMAMPs) with antimicro

32 ction of acetylcholine (ACh) based on enzyme mimics of Au/Ag nanoparticles (NPs).

33 Mimics of BET bromodomains inhibit aberrant ASM cell pro

34 m natural and synthetic amphiphiles serve as mimics of biological membranes and enable the delivery o

35 the candidacy of glycodendrimersomes as new mimics of biological membranes with programmable glycan

36 Mimics of both miRNAs could deplete endogenous ATRX, and

37 6 lncRNAs were identified as putative target mimics of cassava known miRNAs.

38 alt interactions with butyramide as a simple mimic of cation interactions with protein backbones.

39 protein 1 (LMP1) is an EBV-encoded oncogenic mimic of CD40 that can be re-expressed in PBMCs during S

40 Synthetic mimics of cells, such as liposomes, are typically incapa

41 ipid monolayers were employed as a simple 3D mimic of cellular compartments to reconstitute Min prote

42 introduced decoys that present high-affinity mimics of cellular receptors.

43 YIK-amide, have been coupled to exchangeable mimics of Chol (cholesterol) and Phos (1,2-dipalmitoyl-s

44 pulsive interactions between an exchangeable mimic of cholesterol and an exchangeable mimic of a low-

45 +) blockage property, we engineered a set of mimics of CNG channel pores for both structural and func

46 now it has not been possible to access pure mimics of complex PTMs.

47 Aicardi-Goutieres syndrome is a mendelian mimic of congenital infection and also shows overlap wit

48 opic investigations on a series of synthetic mimics of cytP450 indicate that a thiolate-bound ferric

49 odel hydrophobic- and hydrophilic-rich phase mimics of dentin adhesive polymerize similarly and 2) to

50 lvent after a pressure-cooker treatment as a mimic of desorber conditions.

51 2-O-tetradecanoylphorbol-13-acetate (TPA), a mimic of diacylglycerol and PKC activator), hypertonic s

52 restriction) from bacteriophage T7 acts as a mimic of DNA and inhibits all Type I restriction/modific

53 ) protein of bacteriophage T7 is a molecular mimic of double-stranded DNA and a highly effective comp

54 These dendrimersomes provide mimics of double-bilayer and multibilayer biological mem

55 eered nanostructures could provide effective mimics of ECM for investigation and control of the initi

56 Poxviruses encode K3L, a mimic of eIF2alpha, which is the substrate of protein ki

57 secreted peptides that function as molecular mimics of endogenous plant peptides to promote parasitis

58 Soluble mimics of Env have proven challenging to obtain and have

59 Cys, i-K3Cys) were used to represent minimal mimics of eukaryotic SNARE motifs.

60 ds, which suggests that it might be a useful mimic of ferredoxin cofactors.

61 xpress them as fusions with Spinach, an 'RNA mimic of GFP'.

62 These sensors are based on Spinach, an RNA mimic of GFP, and they have successfully been used to im

63 These RNA mimics of GFP provide an approach for genetic encoding o

64 we show that the P39 peptide is a structural mimic of glyceraldehyde 3-phosphate dehydrogenase (GAPDH

65 annels as they behave as inorganic molecular mimic of glycerol, this is the first report where metall

66 have been successfully synthesized as novel mimics of glycoglycerolipids and glycosphingolipids.

67 that residual attractions are present under mimics of good solvent conditions, and for NTL9 they res

68 mportantly, a synthetic exogenous soluble EL mimic of GraS protected the parental MW2 strain against

69 etically encoding fluorescent RNAs using RNA mimics of green fluorescent protein (GFP).

70 of various forms of Ras (loaded with GDP and mimics of GTP or nucleotide-free) at the allosteric and

71 l nucleophiles generated biologically active mimics of H3 with posttranslational modifications includ

72 e hypothesized that a synthetic nanoparticle mimic of HDL (HDL NP) that binds SR-B1 and removes chole

73 m, we tested a library of small, nonpeptidic mimics of HDPs (smHDPs) and identified compounds that ki

74 the most promising antigenic and structural mimics of HIV-1 Env is the SOSIP.664-stabilized soluble

75 d residues can serve as effective structural mimics of homologous alpha-amino acid residues within a

76 e (LdTyrRS) namely, aminoacylation, and as a mimic of host CXC chemokine.

77 Sca2, a mimic of host formins [4, 5], was later shown to be requ

78 Binding was specific because the T. cruzi mimic of host GFLs, named TGFL, did not react with GFL c

79 and programmed cell death are manipulated by mimics of host proteins encoded by pathogenic bacteria.

80 eptides) have been investigated as synthetic mimics of host-defense peptides in recent years.

81 ations for the use of cell lines as faithful mimics of in vivo epigenetic and physiological processes

82 t type 1 IP(3)R (IP(3)R1) revealed that 6, a mimic of Ins(4,5)P(2), is only 4-fold less potent than I

83 s data indicate that COR acts as a molecular mimic of JA-Ile, the mechanism by which JA-Ile and COR a

84 singly, we found that K16Q mutation in H4, a mimic of K16 acetylation, leads to a structural disorder

85 Here we test a variety of grommet-like mimics of K30 capsular polysaccharide on wild-type Wza a

86 An HDAC inhibitor based on a cyclic peptide mimic of known structure, linked by an aliphatic chain t

87 o generate specific numbers of PM mimics (PM(Mimics)) of known composition for dry, direct deposition

88 of the inhibitors citrate and a phosphinate mimic of l-Ala-d-Asp.

89 DADMe-Immucillin-H synthesized with ribosyl mimics of l-stereochemistry.

90 ssue engineering substrates, or developed as mimics of living tissue.

91 KL(4) is a 21-residue functional peptide mimic of lung surfactant protein B, an essential protein

92 21-residue peptide employed as a functional mimic of lung surfactant protein B, which successfully l

93 onstrated to produce a constitutively active mimic of LuxO approximately P.

94 ing that Pto may have evolved as a molecular mimic of LysM-RLK kinase domains.

95 Under-recognized mimics of medium-vessel vasculitis include segmental art

96 An acetyl-mimic of MEK1 increases inappropriate growth properties,

97 has been applied to the design of structural mimics of membrane active antimicrobial peptides (AMPs)

98 we address this problem in the context of a mimic of microRNA-122 by employing novel nucleobase and

99 Both transfection of mimics of microRNA-192 or -215 and ALCAM knockdown by an

100 However, mimics of microRNA-192 or -215 significantly increased g

101 rovide the first structure of an acetylation mimic of mIDH2 and new insights into the regulatory mech

102 y transfecting cells with an inhibitor and a mimic of miR-146a.

103 reatment of these microglia with a synthetic mimic of miR-155 restored the inflammatory response to a

104 Mimics of miR-100 and miR-101 inhibited expression from

105 Furthermore, mimics of miR-185 and miR-186 blocked transforming growt

106 as increased in THP-1 cells transfected with mimics of miR-29b, miR-125a-5p, or miR-155.

107 Transfection studies using mature miR mimics of miR-490 and miR-1192 that target Foxp3 and IL-

108 d whether minimally selective small molecule mimics of missing protein channels might be capable of c

109 Cyanide, a mimic of molecular oxygen, was found to bind to the meta

110 refore, we postulate selenite is a molecular mimic of monocarboxylates which allows selenite to be tr

111 However, acetylation mimics of MORF4L1, including K148L and K148Q, abolished

112 Designing molecular mimics of MoS2 edge sites is an attractive strategy to u

113 Expression of a double acetylation mimic of MPC2 (K19Q/K26Q) in H9c2 cells was sufficient t

114 The feasibility of these novel compounds as mimics of MUC1 antigens has been validated by the X-ray

115 nt approach for generating glycosulfopeptide mimics of N-terminal PSGL-1 through development of a ste

116 his report, hydrolytically stable structural mimics of N7-guanine-conjugated DPCs were generated by r

117 of the currently missing technologies is the mimic of natural photosynthesis to convert carbon dioxid

118 ing is an attractive technique for preparing mimics of natural and biological receptors.

119 ical porous columns and serve as fundamental mimics of natural porous helix-forming proteins and supr

120 By in vitro screening of small molecule mimics of naturally occurring host defense peptides (HDP

121 selected for NAE activation can function as mimics of Nedd8 to form thioester conjugates with NAE an

122 A metallopeptide-based mimic of nickel-containing superoxide dismutase was used

123 d also exhibits an impressive potential as a mimic of nucleosides, carbohydrates, PNA, amino acids, a

124 ed enzymes that are supplied with cyanide, a mimic of O2 (-) Studies with CDH and its isolated heme b

125 r of NifEN(M) as a structural and functional mimic of one catalytic alphabeta-half of NifDK while sug

126 constructs as well as oligonucleotide-based mimics of parts of the origin to examine the initiation

127 c structure 1 were conceived as "minimalist" mimics of peptidic beta-turn structures.

128 able reusability, thus making it a promising mimic of peroxidase catalysts.

129 a constitutively active variant (acetylated mimic) of PGAM1 stimulated flux through glycolysis.

130 erall, formacetal appears to be an excellent mimic of phosphate linkage in RNA and an interesting mod

131 atural products containing a C-P bond act as mimics of phosphate esters and carboxylic acids, thereby

132 t, the Hsp27 phospho-mimic is only a partial mimic of phosphorylated Hsp27, both in self-association

133 allographic structure of L-PYK with the S12D mimic of phosphorylation indicates that Cys436 is oxidiz

134 bstituted those serines with aspartic acids, mimics of phosphoserines, and investigated the propertie

135 anine (cmF) and carboxyphenylalanine (cF) as mimics of phosphotyrosine (pY).

136 molecular photonic signal transducer and two mimics of photosynthetic photoregulatory processes are d

137 se proteins have been shown to act as ligand mimics of plant CLE peptides and are required for succes

138 ], the unique apolipoprotein of Lp(a), and a mimic of plasminogen.

139 tely discriminated nitroaromatics, which are mimics of plastic explosives.

140 ed azetidine-2-carboxylic acid (Aze), a dual mimic of proline and alanine, is activated by both human

141 hat are 1-2 nm in diameter act as functional mimics of protein channels, and have been used to explor

142 In the search for synthetic mimics of protein secondary structures relevant to the m

143 chemistry is the identification of effective mimics of protein secondary structures that act as inhib

144 s suggest that rationally designed synthetic mimics of protein subdomains that target the transcripti

145 We also determine that genetic "mimics" of [PSI+] account for up to 80% of all phenotype

146 ings suggest that RaxX serves as a molecular mimic of PSY peptides to facilitate Xoo infection and th

147 ng only a single phosphocysteine (pCys) as a mimic of pThr at 180 was sufficient to switch the kinase

148 Persistent expression of Ag, a mimic of self-antigen, leads to functional inactivation

149 monium ions that were previously designed as mimics of several carbocations are actually better mimic

150 al feeding experiments using synthetic miRNA mimics of Sex-miR-10-1a, Sex-miR-4924, and Sex-miR-9 res

151 pt materials scientists to pursue biopolymer mimics of silk with high performance yet light weight.

152 oheximide, or Smac mimetic, a small molecule mimic of Smac/Diablo protein.

153 ector caspases, and therefore small molecule mimics of Smac are not able to reverse inhibition of the

154 Transition state analogue mimics of small oligonucleotide substrates of saporin-L1

155 y boosting cellular levels of Mn-antioxidant mimics of SOD.

156 To develop a non-natural, bioactive mimic of SP-C and to investigate the effects of side cha

157 However, creating an accurate mimic of SP-C that retains its biophysical surface activ

158 The generation of non-natural mimics of SP-B and SP-C has previously been restricted t

159 lity of the 1:1 complex of NCp7 with a 20mer mimic of stem-loop 3 RNA (SL3, also called psi-RNA, in t

160 lts are a promising advance toward synthetic mimics of streptavidin/biotin.

161 spicion and the need to exclude the frequent mimics of stroke in childhood.

162 al assemblies--potentially as more efficient mimics of structural color as it occurs in nature.

163 We report on a simple mimic of such a system that displays transient, sequence

164 Any artificial mimic of such systems designed for solar fuels productio

165 s have shown each to be capable of producing mimics of such marks.

166 h a H2O2-responsive MRI contrast agent and a mimic of superoxide dismutase (SOD).

167 o acid sequence identity, Ps-HppE is a close mimic of Sw-HppE, representing a second example of a non

168 However, the new cyclic peptide mimic of Tat represents a new class of ligands with a un

169 These results suggest that all peptidic mimics of Tat induce the same dynamics in TAR within thi

170 ouse was initially described as a phenotypic mimic of Tetralogy of Fallot with pulmonary atresia; how

171 e, water-soluble receptor 1a as a structural mimic of the active site in UDG.

172 ere, we report the first Fe-based functional mimic of the active site of [Fe]-hydrogenase, which was

173 the step-by-step construction of a prototype mimic of the AIS that we call an adaptive immune respons

174 ater (WS treatment) prior to infection, as a mimic of the aquatic environment of Legionella.

175 (EBV) protein latent membrane 2a (LMP2a), a mimic of the B cell receptor, provides constitutive surv

176 tify BRMS1 as the first eukaryote structural mimic of the bacterial IpaH E3 ligase family and establi

177 We synthesized a macrocyclic peptide mimic of the beta-hairpin from EC869 toxin and solved it

178 coli acyl carrier protein and FabA, a direct mimic of the biological process.

179 Using octatrienoic acid as a mimic of the C(56) polyenoic acid scaffold of ECO-02301,

180 We have constructed a synthetic mimic of the carboxysome, a cyanobacterial carbon-fixing

181 t membrane protein 1 (LMP1), is a functional mimic of the cellular receptor CD40, but signals to B ly

182 is noncleavable but is a partial biological mimic of the cleaved form UmuD', has been identified.

183 It is also a stable structural mimic of the damage induced by the nitrofurazone family

184 The biocompatibility of a triazole mimic of the DNA phosphodiester linkage in Escherichia c

185 l-12-myristate-13-acetate, a pharmacological mimic of the downstream mediator diacylglycerol in alpha

186 -peptide-HLA-B*18:01 complex is a structural mimic of the EBV peptide-HLA-B*18:01 complex, and that t

187 -tyrosine and (R)-1-phenyl-1,2-ethanediol, a mimic of the enediyne core.

188 vity relationship, we engineered a molecular mimic of the entire gp41 N-HR coiled coil using the 5-He

189 Zinc(II) cyclen, a small molecule mimic of the enzyme carbonic anhydrase, was evaluated un

190 d formation and site-directed mutagenesis, a mimic of the enzyme.substrate complex has been trapped.

191 erol and 10 +/- 2 cm/s in a 100% cholesterol mimic of the experimentally observed noncrystalline chol

192 excited-state electron donor, a dinucleotide mimic of the FADH2 cofactor containing O at the 5'-end a

193 ate ferryl precursor, and a vanadium(IV)-oxo mimic of the ferryl intermediate in the l-arginine 3-hyd

194 Although 1C8 was designed to be a structural mimic of the fused tetracyclic indole compound IDC16 tha

195 This nucleoside was incorporated into a mimic of the glutamate receptor B (GluR B) mRNA R/G edit

196 nt Spinach aptamer, which is a synthetic RNA mimic of the Green Fluorescent Protein, from its split s

197 One of these effectors is IpgB1, a mimic of the human Ras-like Rho guanosine triphosphatase

198 of such exposures, we developed an in vitro mimic of the in vivo event of exposure to PM contaminate

199 blocked by addition of synstatin, a peptide mimic of the integrin activating region present on the s

200 ure to produce a highly populated structural mimic of the intermediate state.

201 roaches: a truncation to generate a fragment mimic of the intermediate, and selective destabilization

202 ost often studied in dilute solution, a poor mimic of the intracellular space of eukaryotic cells, wh

203 y switchable proton conduction, a functional mimic of the ion transport within a cell membrane, has y

204 The TIP peptide, a mimic of the lectin-like domain of TNF, activates ENaC b

205 I)-CO complex of the H103G H-NOX mutant as a mimic of the ligand-free and kinase-inhibitory Fe(II)-NO

206 Further, a neurochemical mimic of the light input pathway evoked larger shifts in

207 y enhanced responsiveness to a neurochemical mimic of the light input pathway to the SCN.

208 n of Cys78 with maleimide creates a solution mimic of the Lys-ligated cyt c that has enhanced peroxid

209 -II, a histidine-containing branched peptide mimic of the malarial biomarker Plasmodium falciparum hi

210 s dipeptidyl-peptidase IVA (DppIVA), a close mimic of the mammalian ectopeptidase CD26, which modulat

211 e Fe protein variant may be a conformational mimic of the MgATP-bound state of the native Fe protein

212 te peptide (CP20) and ATP to produce a close mimic of the Michaelis complex.

213 Creating an artificial functional mimic of the mitochondrial enzyme cytochrome c oxidase (

214 us expression of MCT12 and MCT12:214Delta, a mimic of the mutant allele, were used to assess protein

215 specific analysis of a recombinant, trimeric mimic of the native HIV-1 viral spike (BG505 SOSIP.664)

216 uence is a faithful antigenic and structural mimic of the native trimer in its prefusion conformation

217 Using a small molecule mimic of the natural hexaketide starter unit, we reconst

218 nd acts as a structurally distinct synthetic mimic of the natural ligand, flavin mononucleotide, to r

219 x of vancomycin with N-acetyl-D-Ala-D-Ala, a mimic of the natural muramyl peptide target, and refined

220 P450cin complexed with nitric oxide, a close mimic of the O(2) complex, shows that Gly238 is likely t

221 ha-d-mannosyl-d-mannose (2alpha-MB), a short mimic of the O9a polymer.

222 oglutarate dioxygenase inhibitor is a better mimic of the overall transcriptional response to hypoxia

223 hem, compounds 2 and 3 appeared to be a good mimic of the parent endogenous thyronamine, T0AM and T1A

224 ntain a sulfamide group as a nonhydrolyzable mimic of the phosphate group in the cognate Ub/Ubl-AMP a

225 by use of methylcobinamide as an appropriate mimic of the physiological base-off corrinoid substrate.

226 A physical mimic of the process using a layered swelling gel captur

227 utants of Srx and Prx, including the Prx-Asp mimic of the Prx-SO(2)(-) species, support a mechanism w

228 rface modified with a photochemically active mimic of the PSII chlorophyll-Tyr-His complex, undergoes

229 ily accepted an N-acetylcysteamine thioester mimic of the reduced pentaketide product of Rdc5 to synt

230 and mammalian ribosomes and an RNA stem-loop mimic of the sarcin/ricin loop (SRL) at a higher catalyt

231 Compared with the dephosphorylation mimic of the seven phosphorylation sites, alanine substi

232 Removal of this covalent mimic of the solvent shell restored the original screw s

233 e ligands are argininamide, a linear peptide mimic of the Tat basic domain and a cyclic peptide that

234 presence of the product acetate or a potent mimic of the tetrahedral intermediate were determined by

235 , suggesting that DADMe-ImmG is an excellent mimic of the transition states for both HsPNP and E:R-PN

236 LMP1 is a constitutively active functional mimic of the tumor necrosis factor receptor superfamily

237 posomal nanoparticle loaded with a synthetic mimic of the tumor suppressor miRNA miR-34a as the activ

238 A mimic of the Wacker process for C horizontal lineO bond

239 Here we show a mimic of the Z-scheme with a molecular tetrad.

240 nate interaction through the provision of a "mimic" of the HLA-encoded peptide derived from the immun

241 erent classes of beta-lactam antibiotics, as mimics of the acyl-D-Ala-D-Ala moiety at the allosteric

242 on a possible SN1 catalytic mechanism and as mimics of the carbocation in the transition state of hUP

243 of the transmembrane helices is preserved in mimics of the cell bilayer, and that the apparent voids

244 y shown that two of these miRNAs function as mimics of the cellular miRNAs miR-155 and miR-142-3p.

245 king in S. aureus using fluorescently tagged mimics of the endogenous substrate of penicillin-binding

246 Whereas azo-bis-ebselens 7 were poor mimics of the glutathione peroxidase (GPx)-enzymes, nitr

247 In search for better mimics of the glutathione peroxidase enzymes, pyridoxine

248 ning compounds, i.e., 1a-h, were prepared as mimics of the green fluorescent protein (GFP) fluorophor

249 More generally, mice often provide poor mimics of the human diseases being modeled.

250 Recombinant trimeric mimics of the human immunodeficiency virus type 1 (HIV-1

251 Mimics of the hydrophilic-rich phase were prepared simil

252 such as Frz-B, WIF-1 and Crescent, are poor mimics of the inductive and patterning activities of Dkk

253 trated by experiments that created synthetic mimics of the interior cavity) or if the interior also a

254 We investigated this hypothesis by making mimics of the intermediate that are the ground-state con

255 that synthetic polymers may not be suitable mimics of the intracellular environment.

256 and 2-azadecalins that are close structural mimics of the m/z 202.126 ion, and showed that they are

257 cal scavenger hydroxyurea and small molecule mimics of the monohydroxylated Trp residue of PreMADH al

258 involves using recombinant, soluble protein mimics of the native trimer.

259 tion of bNAbs is to design soluble, trimeric mimics of the native viral Env trimer.

260 NAC) fatty acid thioesters have been used as mimics of the natural acyl carrier protein pathway inter

261 Although molecular mimics of the natural catalyst have been proposed, they

262 libraries may be considered to be structural mimics of the natural products pramanicin and epolactaen

263 phylococcus aureus, we show that fluorescent mimics of the natural substrate of PBPs (PG stem peptide

264 use beta-lactams are chemical and structural mimics of the natural substrate, resistance mediated by

265 s of nucleotides are considered to be useful mimics of the natural substrates, but direct structural

266 Environmentally useful, small molecule mimics of the peroxidase enzymes must exhibit very high

267 r the first time the design and synthesis of mimics of the phosphopantothenoyl cytidylate, which prov

268 crystal structures of the Michaelis complex mimics of the PKA catalytic subunit (PKAc) were obtained

269 SIP Env trimers are structural and antigenic mimics of the pre-fusion native, surface-presented Env,

270 ts were used to introduce the analogues into mimics of the R/G-editing site found in the pre-mRNA for

271 , we used DNA-gold nanocrystal conjugates as mimics of the R1 plasmid.

272 Iminoribitol mimics of the ribocation transition state in linkage to

273 rene macrocycles bearing phosphines as crude mimics of the rigid backbones of proteins, we demonstrat

274 Using peptide mimics of the S12 protein bearing deuterium at the 3 pro

275 Close mimics of the transition state are hypothesized to retai

276 These catalysts were designed as mimics of the two-point hydrogen-bonding interaction pre

277 antibodies by immunization with recombinant mimics of the viral spike.

278 n an anti-HIV screen to identify structural "mimics" of the fused tetracyclic indole compound 1 (IDC1

279 elming majority of studies on small-molecule mimics of these enzymes entirely ignores the contributio

280 Conversely, transfections with mimics of these miRNAs decreased neutrophil adhesion to

281 Importantly, administration of mimics of these miRNAs with sunitinib or axitinib result

282 Mutational mimics of these modifications (glutamine for acetylation

283 etic polymers have recently been explored as mimics of these natural peptides.

284 Synthetic mimics of these natural structures are highly desired to

285 y of 2,4-difluorotoluene (F), a low-polarity mimic of thymine (T), to form a hydrogen-bonded complex

286 Starting from a noncovalent linear mimic of TMC-95A, a series of dimerized inhibitors using

287 )-L-cysteine, which could be considered as a mimic of Tn antigen.

288 e, while the phosphonyl group is a versatile mimic of transition-states, intermediates, and primary m

289 of several carbocations are actually better mimics of transition state structures for carbocation de

290 e has been probed with a series of synthetic mimics of trehalose dimycolate in binding assays, in str

291 Because these are less than perfect mimics of true biological membranes, the structures are

292 Mimotopes, or peptide mimics of tumor antigens, elicit increased numbers of T

293 Vaccines that incorporate peptide mimics of tumor antigens, or mimotope vaccines, are comm

294 orobenzimidazole, non-hydrogen bonding shape mimics of uracil and hypoxanthine, respectively, is stro

295 de heteroconjugates were generated to act as mimics of UV cross-linked heteroconjugates.

296 Awareness of noninflammatory mimics of vasculitis is essential to avoid unnecessary a

297 a cholera vaccine, the potential of peptide mimics of Vibrio cholerae lipopolysaccharide (LPS) to el

298 t or treatment with cytoplasmic poly(I:C), a mimic of viral dsRNA, activates this pathway to regulate

299 ppaB2 is induced in response to poly(I:C), a mimic of viral dsRNA.

300 Only synthetic TLR7/8 ligand, a mimic of viral ssRNA, induced IL-23 production by LP CD1