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1 e device could be used as a pulse generator, mimicking a cardiac pacemaker delivering pulses of 10muA
3 Viral growth of mutant virus encoding K229R, mimicking a non-acetylated NP lysine residue, is severel
8 ng a high-fat diet (HFD) coupled with sugar, mimicking a Western diet, causes fatty liver disease in
9 utagenesis of lysine 68 to glutamine (K68Q), mimicking acetylation, decreased MnSOD activity in SNc d
12 ide materials in hundreds of gram quantities mimicking actual released materials from coatings and po
14 urity even before secondary tumor formation, mimicking alterations present during tibial metastasis.
21 homeostasis and display physiologic features mimicking animals living under calorie restriction (CR).
23 currents produced by a mutated form of Kv2.1 mimicking apoptosis in a mammalian expression system, an
24 In conclusion, our study identifies SOCS1 mimicking as a feasible therapeutic strategy to halt the
25 ar imprinting furthers the functional enzyme mimicking aspect of nanozymes, and such hybrid materials
29 served that, in cells expressing the phospho-mimicking Atf1 mutant, the presence of Sty1 was complete
30 ruptions in sleep and circadian rhythmicity, mimicking attributes of stress-related conditions as the
31 ent, is extended by preincubation with NMDA, mimicking axonal activity, and shortened by NMDA recepto
32 sferred to the separated hydrophobic domain, mimicking bacterial cell membranes, by using dialysis an
33 1-dependent inflammasome activation and that mimicking biased aPC PAR-1 signaling using parmodulins m
35 rom JDs and JGDs serve as powerful tools for mimicking biological membranes and for biomedical applic
38 e adhesion in vitro assay under shear forces mimicking blood flow, we observed that reduction of endo
44 the distribution of cccDNA under conditions mimicking chronic infections with and without antiviral
45 ronic administration of type I IFN, at doses mimicking chronic viral infection, induced immunosuppres
46 dition, the roasting of solid-state mixtures mimicking coffee beans composition allowed the conclusio
47 ble to those of a hyperacetylated histone H4-mimicking cognate peptide, and demonstrated a dependence
48 ge-induced cell cycle arrest and senescence, mimicking colorectal carcinoma cells with high endogenou
52 vasoinhibins under diabetic or hyperglycemic-mimicking conditions, but that (ii) vasoinhibins can blo
53 g the correct diagnosis and excluding common mimicking conditions, to ensure timely and appropriate m
54 stingly, release deficiency is also observed mimicking constant acetylation at this site (K229Q), whe
56 , treatments with increasing glyceraldehyde (mimicking crosslinking conditions) and chondroitinase-AB
57 light/dark illumination regime, a condition mimicking day/night cycles in certain natural habitats.
58 removed and cold stored for 4 and 18 hours, mimicking DCD organ procurement and conventional preserv
64 emature differentiation of neuroprogenitors, mimicking differentiation defects of Mcph1-knockout neur
66 Due to efficient catalytic activity of HRP mimicking-DNAzyme, the proposed immunosensor exhibited h
67 In this reaction, hemin-binding peroxidase-mimicking DNAzymes ("peroxidymes") mediate the NADH-driv
68 eraction results in the release of a quinone-mimicking drug that generates reactive oxygen species an
69 d bisubstrate analogues-based inhibitors, by mimicking each substrate, the S-adenosyl-l-methionine an
71 OL) on matrices of variable elastic modulus, mimicking either their native environment or conditions
72 ifferentiated from pluripotent stem cells by mimicking embryonic development through stepwise exposur
74 c neoplasms with prominent pigment synthesis mimicking equine melanoma represent a rare variant of bi
76 trum noise, with two intervals on each trial mimicking examples of pre- and post-benefit situations.
77 scales, retaining chemical specificity, and mimicking experimental fabrication conditions, and which
79 an dynamics simulations with realistic units mimicking experimentally realized artificial colloidal s
81 election, with commentary on the fidelity of mimicking facets of the human disease; (2) experimental
86 y processes and, furthermore, are capable of mimicking fundamental processes for directional charge t
87 nd H2O2 depended on the concentration of HRP-mimicking G-quardruplex DNAzyme formed from the binding
89 In vivo chemogenetic excitation of D1-MSNs, mimicking glutamatergic strengthening, promoted alcohol
90 ions) and chondroitinase-ABC concentrations (mimicking glycosaminoglycan depletion) decreased diffusi
91 influence of spacer length (between mannose-mimicking headgroups and quaternary nitrogen centers) in
93 the first step of virus-cell interaction by mimicking heparan sulfate proteoglycans (HSPG), the high
94 ning principles, was conceived to build silk-mimicking hierarchies in two-phase biodegradable blends,
99 nanoparticles with long and flexible linkers mimicking HSPG, allowing for effective viral association
107 ur main findings are as follows: brain edema mimicking hypoosmotic conditions stimulates the formatio
108 use exposure of cultured cells to hypoxia or mimicking hypoxia pharmacologically or genetically incre
109 -induced choroidal neovascularization (CNV), mimicking hypoxia-mediated neovascularization and inflam
110 that T. gondii suppresses pDC activation by mimicking IL-10's regulatory effects through an ROP16 ki
112 ment (JRGCE), California where manipulations mimicking increases in temperature, water, nitrogen and
113 h activation of neutrophils under conditions mimicking infection with S. aureus conferred responsiven
114 , inhibition of histone binding by a histone-mimicking interdomain linker represents another example
115 s (JRCSFvifH42/43DW79S) failed to replicate, mimicking JRCSF without Vif expression (JRCSFDeltavif).
116 uired data files to data processing servers, mimicking just-in-time production strategies from the ma
118 ver, low concentrations of endogenous Abeta, mimicking levels of the peptide in the healthy brain, en
120 ructures for investigating, engineering, and mimicking lipid membrane-related biophysical processes.
123 presence of hyperreflective Langerhans cells mimicking malignant melanocytes was the main cause for m
124 were observed upon AA1 binding for liposomes mimicking mammalian cell membranes, which consist of neu
126 esis that venlafaxine deposition in the egg, mimicking maternal transfer of this antidepressant, disr
128 The crystal structure of phosphorylation-mimicking Mep2 variants from C. albicans show large conf
130 ranslocates from one anchor site to another, mimicking motor proteins, is realized through a toehold-
132 ion, we demonstrate that the phosphorylation mimicking mutant of Smurf1, Smurf1 T306D, prevents PIPKI
134 ndicated that wild-type AQP2 and the phospho-mimicking mutants had similar overall structure but disp
138 rove beetle (Staphylinidae) that exhibit ant-mimicking "myrmecoid" body forms and are behaviorally ac
139 ency.SIGNIFICANCE STATEMENT In a mouse model mimicking n-3 PUFA dietary deficiency during adolescence
140 we demonstrate that high-density lipoprotein-mimicking nanodiscs coupled with antigen (Ag) peptides a
143 ed antigen 85B (Ag85B)/peptide 25-loaded BCG-mimicking nanoparticle formulation was evaluated in vivo
144 bacteremia model, treatment with macrophage mimicking nanoparticles, termed MPhi-NPs, reduced proinf
148 iques have been proposed to design materials mimicking natural materials, such as layer-by-layer depo
149 efined, and there is a lack of animal models mimicking natural oral human infection leading to paraly
150 the associative and dissociative processes, mimicking naturally occurring reactions and giving rise
151 owever, we are yet to realize the benefit of mimicking nature's Murray networks in synthetic material
152 a specific cardiac variant of Fabry disease mimicking nonobstructive hypertrophic cardiomyopathy.
154 diminishes viral polymerase activity, while mimicking NP hypo-acetylation at these sites has no effe
157 rently restricted in scale and often rely on mimicking or enhancing natural communities, calling for
159 e retroelements traffic to the germ plasm by mimicking oskar RNAs and engaging the Staufen-dependent
160 no acids were incorporated into a histone H4-mimicking peptide and their affinity for BRD4(1) was ass
163 The imaging system was tested with tissue-mimicking phantoms and an ex vivo chicken liver through
164 e feasibility of the method was examined for mimicking phase I metabolism reactions of amodiaquine, b
172 izing different substrates and in conditions mimicking physical exercise and the changes in their cap
175 model of food allergy with the advantage of mimicking polysensitization and low food-antigen IgE tit
177 he biointerfaced nanorobots display platelet-mimicking properties, including adhesion and binding to
181 eovascularization, serous retinal elevations mimicking retinal folds, increased choroidal thickness,
183 s of cationic amphiphiles containing mannose-mimicking shikimoyl headgroup are promising DNA vaccine
185 tion, the suggested approach can be used for mimicking some cyclic (Sisyphus) processes in nature, su
186 oating biofilms in artificial sputum medium, mimicking sputum of CF lungs where P. aeruginosa is an i
188 in phosphatase 1 (PP1) is recruited to a DSB-mimicking substrate in Xenopus egg extracts and sites of
190 s, significant efforts have been made toward mimicking such architectures and functions in artificial
197 the excitation of high frequency components, mimicking the appearance of near-bright solitary waves o
198 n formation in hyperglycemic ApoE(-/-) mice, mimicking the atheroprotective phenotype of CrP-treated
199 ically encumbered triphenylphosphine motifs, mimicking the basic sites employed in frustrated Lewis p
200 5) could block endogenous receptor assembly, mimicking the biological effect of decoy receptors that
201 We demonstrate that, if the constraints mimicking the bound proteins are properly applied, the p
202 carrying equatorial amino or hydroxyl groups mimicking the bound side chains of neomycin and paromomy
203 n lid region bound in a helical conformation mimicking the bound structure of p53, suggesting lid reg
204 ts are taken from time varying distributions mimicking the bursting behaviour of observed saltatory g
205 ive conditioning enhanced MB odor responses, mimicking the cAMP-dependent plasticity in directionalit
207 ty, can alter vascular growth and integrity, mimicking the changes that exist in tumor vasculature.
209 benefit from reductions in predation risk by mimicking the coloration, body shape, and/or movement of
212 oduction of reactive oxygen species, closely mimicking the defective immune functions observed in bet
214 ly, IPV was released in two separate bursts, mimicking the delivery of two boluses approximately one
215 ility exhibited by nature can be achieved by mimicking the design principles of natural photosyntheti
216 -formylcytosine accumulation, thus partially mimicking the diabetic epigenetic landscape in cells of
217 upon cyclic rapid laser heating and cooling mimicking the direct energy deposition of Ti-6Al-4V in r
218 ronephric glomerular and tubular dysfunction mimicking the early phenotype of human cystinotic patien
219 bottom-up self-assembly of new biomaterials mimicking the ECM to directly impact cell behaviors.
220 ptic activation of cortical layer-4 neurons, mimicking the effect of a single afferent spike from a s
221 orming ability of VHL-deficient CC-RCC, thus mimicking the effect of Y-27632 treatment, whereas downr
223 of tissue factor enhanced clot contraction, mimicking the effects of tissue factor expressed on the
224 tissue fibrosis, with bleomycin-treated mice mimicking the fibrotic and inflammatory components of SS
225 c and counter ethanol's effects in vesicles, mimicking the findings of previous electrophysiological
226 replaced by either alanine or aspartic acid, mimicking the fully nonphosphorylated and the fully phos
227 tudies of synthetic phenylthiosemicarbazones mimicking the function of acid-sensing (proton-gated) io
229 esvirus (KSHV) enhances protein synthesis by mimicking the function of the cellular protein S6 kinase
230 synthetic nanofluidic devices and materials, mimicking the gating, rectifying, and adaptive functions
233 aintained after thermal heat shock and after mimicking the heat-shock response transcriptional progra
234 mouse models of Tp53- and Atm-defective CLL mimicking the high-risk form of human disease and show t
240 es filling the site I cavities of IL-6, thus mimicking the interactions of Phe(229) and Phe(279) of I
241 of alpha,beta-unsaturated nitriles, thereby mimicking the intermediate Opsin-derived, protonated Sch
242 dy examined whether a cell-permeable peptide mimicking the kinase-inhibitory region of suppressor of
243 posomes poor in sphingomyelin/cholesterol or mimicking the lipid composition of the mitochondrial out
245 aberrantly favoring muscle relaxation, thus mimicking the low-Ca(2+) effect of troponin even in acti
246 G-quadruplex (G4)-containing substrates mimicking the mammalian immunoglobulin switch regions ar
248 rct border region; 2) direct stretch of CFBs mimicking the mechanical environment of the infarct regi
249 lds it from the aqueous environment, thereby mimicking the mode of action of a natural Diels-Alderase
250 tended layers of light-harvesting complexes, mimicking the modular antenna/transducer architecture of
251 d lamellar characteristics of the construct, mimicking the native hierarchical architecture of the AF
253 fied by a synthetic single-guide RNA (sgRNA) mimicking the natural dual trans-activating CRISPR RNA (
255 h was lost in mice deficient in eosinophils, mimicking the obese phenotype, and was restored upon eos
257 having protonated or unprotonated cytosines, mimicking the pH 5.0 and 8.0 conditions, highlight the i
258 f H3K9me2 into adjacent euchromatic regions, mimicking the phenotype observed in Drosophila JIL-1 kin
259 n of the retinal neural epithelium in mouse, mimicking the phenotype of Fz5/Fz8 compound conditional
260 nt distributions of PE in the planar bilayer mimicking the plasma membrane were examined: exclusively
261 We designed multiple synthetic peptides mimicking the predicted cleavage sites of neurotoxin pre
262 eered 2 different IL-1beta variants, thereby mimicking the process of cytokine modification occurring
263 he motor cortex at an interstimulus interval mimicking the rhythmicity of descending late indirect (I
264 anoscale swimmers have taken the approach of mimicking the rotary motion of helical bacterial flagell
265 erted AtTPC1 to a Na(+)-selective channel by mimicking the selectivity filter of HsTPC2 and identifie
266 ill cover materials and devices designed for mimicking the skin's ability to sense and generate biomi
267 ed fabrication of high-strength structure by mimicking the spinning process of spider silk, currently
268 othelial cell barrier function on substrates mimicking the stiffness of healthy and tumor tissue.
269 Biomimetic supramolecular dual networks: By mimicking the structure/function model of titin, integra
270 f bioinspired assemblies not only allows for mimicking the structures of living systems, but it also
272 boring patches embedded in a cortical sheet, mimicking the two digit regions, were costimulated at di
274 In cholesterol-containing lipid membranes mimicking the virus envelope, (15)N NMR spectra show tha
276 structurally elusive, and crystal structures mimicking these gating events require mutations in or st
277 (basement) membrane rupture in keratoconus, mimicking this animal model and highlighting the clinica
279 Conversely, in the absence of nerve injury, mimicking this increase reduces the Kcna2 promoter activ
282 We explored the potential of cyclic peptides mimicking this structure to elicit anti-HCV antibodies.
284 linearized plasmid with 3-P-blocked termini, mimicking those at X-ray-induced strand breaks, to recap
285 benzomorpholine scaffold allows side chains mimicking those found in 1,4-benzodioxane lignans to be
287 model to generate multiple setting scenarios mimicking those in sub-Saharan Africa and considered the
288 le, these ligands are capable of effectively mimicking those interactions of dopamine and the D2R tha
293 ceptor orientation on the electrode surface, mimicking TLR-4's role in a cellular context, was essent
294 gineering a green fluorescence protein (GFP)-mimicking turn-on RNA aptamer, Broccoli, into two split
295 as elevated under in vitro growth conditions mimicking unfed ticks compared to the level in fed ticks
296 designed a novel particulate based pathogen-mimicking vaccine delivery system (PMVDS) to target anti
297 aled that different OxPls species in the MOM-mimicking vesicles can have opposing effects on Bax pore
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