ライフサイエンスコーパス: mineralized tissue

1 er scaffold (19 +/- 8% osteoid and 10 +/- 2% mineralized tissue).

2 ted to the ability of these cells to augment mineralized tissue.

3 ressed where osteoblasts attempted to repair mineralized tissue.

4 ysical and chemical properties of the mature mineralized tissue.

5 ft material, and 39.6% connective tissue/non-mineralized tissue.

6 al cavity and which control the formation of mineralized tissues.

7 hromosome 5 near other genes associated with mineralized tissues.

8 narily reserved molecule highly expressed in mineralized tissues.

9 r role in the ability of organisms to create mineralized tissues.

10 and overall hypomineralization in the dental mineralized tissues.

11 s proteolytically processed fragments in the mineralized tissues.

12 y to control the structure and properties of mineralized tissues.

13 t in the extracellular function of FAM20C in mineralized tissues.

14 re unique to cells responsible for producing mineralized tissues.

15 ave not been isolated or confirmed in mature mineralized tissues.

16 provide clues to the evolutionary origins of mineralized tissues.

17 portant role in the embryonic development of mineralized tissues.

18 ing evolution, particularly the evolution of mineralized tissues.

19 stomorphometric analysis of the newly formed mineralized tissues.

20 rent organization of the mineralized and non-mineralized tissues.

21 onal cleavage fragments found in extracts of mineralized tissues.

22 ls, we demonstrate that Dmp1 is specific for mineralized tissues.

23 formation, is largely restricted to cells in mineralized tissues.

24 otal tissue area; mean +/- SD; p < 0.05) and mineralized tissue (14 +/- 2%; P < 0.05) within a rat cr

25 te significantly increased the generation of mineralized tissue (19 +/- 4%; P < 0.05) compared with m

26 tooth, which consists of two characteristic mineralized tissues, a highly mineralized surface layer

27 2-deficient osteoclasts are unable to resorb mineralized tissue and cannot form an acidified, extrace

28 reased interfacial strength between cultured mineralized tissue and titanium, but did not alter the i

29 lls from long-standing IDDM patients to form mineralized tissue and to determine whether these cells

30 tics may be altered in their ability to form mineralized tissue and to respond to growth factors, fun

31 ctions as an extracellular matrix protein in mineralized tissues and a cytokine that is active in cel

32 ple and distinct roles in the development of mineralized tissues and that the influence of ENPP1 on o

33 . the osteonal structures in which layers of mineralized tissue are organized in lamellae around a ce

34 Vertebrate mineralized tissues are vital to the adaptive evolution

35 However, genes more specific to mineralized tissues arose subsequent to the genome dupli

36 gnized that this protein is expressed in non-mineralized tissues, as well as in cancerous lesions.

37 significant difference in the expression of mineralized tissue-associated genes, including BSP and R

38 The expression of mineralized tissue-associated genes, including Type I co

39 After 90 days, the mean percentages of mineralized tissue at the interface in the test and cont

40 o examine adhesion molecules associated with mineralized tissues, bone sialoprotein (BSP) and osteopo

41 the concept that Msx2 controls formation of mineralized tissues by inhibition of the Wnt/beta-cateni

42 +/- 13.4% of the interface area filled with mineralized tissue, compared to 17.14% +/- 8.6% in the c

43 ic matrix proteins of dentin and enamel, the mineralized tissues comprising a tooth crown.

44 Despite the recognition that mineralized tissues contain proteins that are unusually

45 These tissues thus form a mineralized-tissue continuum.

46 Cementum is a mineralized tissue covering the tooth root that function

47 ized structures (connective tissue/other non-mineralized tissue [CT]).

48 bone may be significant contributors to the mineralized tissue defects in human patients and animals

49 eded in these scaffold systems, and distinct mineralized tissue differentiation were noted within the

50 tomesenchyme culminating in the formation of mineralized tissues, enamel, and dentin.

51 hile the hardness and elastic modulus of the mineralized tissue, evaluated by nano-indentation, were

52 anted into nude mice, DPSC/CTL cells induced mineralized tissue formation with significant increases

53 ibitors, like PPi, play in the regulation of mineralized tissue formation.

54 ides one well accepted paradigm for studying mineralized tissue formation.

55 In situ hybridization showed that the mineralized tissue formed by cementoblasts gave strong s

56 The amount of dentin-associated mineralized tissue formed in teeth with residual bacteri

57 es from cholesteric phase fibre bundles, and mineralized tissues from hierarchically organized fibres

58 ting that increased vascularization enhances mineralized tissue generation, but not necessarily osteo

59 n to be essential for transcription of other mineralized tissue genes, is also required for ameloblas

60 ng factors which facilitate the formation of mineralized tissue has significant clinical ramification

61 cture and composition, or microstructure, of mineralized tissues has an important role to play in det

62 h for designing new therapies for preserving mineralized tissue health.

63 Cementum is a critical mineralized tissue; however, control of its formation re

64 It is the only epithelial-derived mineralized tissue in mammals and has a distinct micro-

65 Enamel formation produces the most highly mineralized tissue in the human body.

66 se the production of collagenous protein and mineralized tissue in vitro, as compared to unsupplement

67 he required biochemical machinery to produce mineralized tissue in vitro, has been generated.

68 basis for a novel genetic system for various mineralized tissues in skeleton and teeth.

69 Requisites for development of this highly mineralized tissue include cell differentiation; product

70 ng the material properties of bone and other mineralized tissues, including mineralization, crystalli

71 t time that the signal in (31)P MR images of mineralized tissue is enhanced by a (1)H-(31)P nuclear O

72 Mineralized tissue is vital to many characteristic adapt

73 ral spacing of the collagen molecules in wet mineralized tissues is exactly proportional to the inver

74 The formation of mineralized tissues is governed by extracellular matrix

75 P-1-Tolloid-like proteinases in formation of mineralized tissues is indicated, via proteolytic proces

76 BSP expression in mineralized tissues is upregulated at onset of mineraliz

77 not unique to dentin but is present in other mineralized tissues like long bone, calvaria, and amelob

78 Cementum, a mineralized tissue lining the tooth root surface, is des

79 Proper formation of cementum, a mineralized tissue lining the tooth root surface, is req

80 Dentin matrix protein-1 (DMP1) is a mineralized tissue matrix protein synthesized by osteobl

81 Unlike other mineralized tissues, mature dental enamel is primarily (

82 that other signaling pathways important for mineralized tissue morphogenesis such as the Smad pathwa

83 Since there are 3 fragments within the mineralized tissues [N-terminal, C-terminal (57K), and a

84 is an extracellular matrix protein found in mineralized tissues of the skeleton and dentition.

85 entified dental pulp stem cells can generate mineralized tissue on titanium via the osteoblastic phen

86 ) by testing a hypothesis that DPCs generate mineralized tissue on titanium.

87 n, teeth, and otoconia are normally the only mineralized tissues or organs in the human body.

88 ity (FAM) 20 gene family are associated with mineralized tissue phenotypes in humans.

89 study is to enrich the current knowledge of mineralized tissue phosphorylation events by analyzing t

90 of bio-inspired nanostructured materials for mineralized tissue repair and regeneration.

91 al for developing bio-inspired approaches to mineralized tissue repair and regeneration.

92 reated defects were filled with trabeculated mineralized tissue similar to, but more mature, than tha

93 ration and stemness and the MSC-specific and mineralized tissue-specific gene expression of P-MSCs an

94 have been reported to induce expression of a mineralized tissue-specific marker, bone sialoprotein (B

95 Mineralized tissues such as dentin and bone assemble ext

96 Such contrasts between two mineralized tissues suggest distinct pathways of biomine

97 did not alter the intrinsic strength of the mineralized tissue, suggesting a role for proteoglycan/g

98 tion of CTR-positive cells to the surface of mineralized tissues suggests that bone and/or calcified

99 he outermost layer of teeth, is an acellular mineralized tissue that cannot regenerate; the mature ti

100 Healthy dentin, the mineralized tissue that makes up the bulk of the tooth,

101 whale Mesoplodon densirostris are two highly mineralized tissues that contain over 95 wt.% mineral, i

102 genous tissue and is thus an exception among mineralized tissues that derive from the mesenchyme.

103 cant role in maintenance and regeneration of mineralized tissue, the success of procedures, such as g

104 To efficiently degrade mineralized tissue, these multinucleated giant cells sec

105 noglycans were immunochemically localized at mineralized tissue-titanium interfaces.

106 Neither acute inflammation nor mineralized tissue was noted in any of the subcutaneous

107 a higher percentage of the area filled with mineralized tissue was seen at 90 days compared to 30 da

108 e spiked with calcium threonate, the area of mineralized tissue was significantly greater than in asc

109 efects treated with carrier + cementoblasts, mineralized tissues were noted at the healing site with

110 se 'hit' combinations directed hMSCs to form mineralized tissue when conditions were translated to 3D