ライフサイエンスコーパス: mislocalized

1 produces bicaudal embryos when oskar mRNA is mislocalized.

2 eased by 25%, and hemidesmosome proteins are mislocalized.

3 audin-3, apical tight-junction proteins, are mislocalized.

4 of membrane proteins in microvilli, is also mislocalized.

5 some other fragments lacking this region are mislocalized.

6 as rhodopsin, arrestin, and transducin, are mislocalized.

7 oteins exhibited reduced expression and were mislocalized.

8 SHORTROOT and SCARECROW are misexpressed or mislocalized.

9 ing NHE1-KRA2 because scaffolding by NHE1 is mislocalized.

10 -)Nrl(-/-) mice was minimal, and opsins were mislocalized.

11 tor, the CD is disorganized and REMPA-YFP is mislocalized.

12 mponents of the midbody are either absent or mislocalized.

13 the Purkinje cells are poorly developed and mislocalized.

14 Rce1 or Icmt, farnesylated Ras proteins were mislocalized.

15 cle progenitors are expanded, and ISEMFs are mislocalized.

16 ally decreased and that the remaining pRB is mislocalized.

17 e SH3 domain is overexpressed, paramyosin is mislocalized.

18 ore, enzymes that support aECM stability are mislocalized.

19 Golgi, Rh1 is aberrantly glycosylated and is mislocalized.

20 hand side of the cell or two nuclei with one mislocalized.

21 ongation zone of twd1 roots, attributable to mislocalized ABCB transporters and suppressed by an auxi

22 n both growth and nuclear segregation due to mislocalized actin assembly.

23 Dkk-1 exposure induced mislocalized activation of Cdc42 in migrating cells, whi

24 with suggestions that AlgL serves to degrade mislocalized alginate that is trapped in the periplasmic

25 of apical-basal polarity, such as ZO-1, were mislocalized along the lateral and basal membranes of fi

26 esulting intermicrovillar adhesion links are mislocalized along the microvillar axis rather than enri

27 swollen, but neither opsin nor arrestin was mislocalized, although IFT88 accumulated in the distal r

28 raspeckle function in human diseases because mislocalized amyotrophic lateral sclerosis (ALS)-linked

29 In cam-1 mutants, ACR-16 is mislocalized and ACR-16-dependent currents are disrupted

30 Without chromophore, cone opsins are mislocalized and cones degenerate rapidly (e.g., Rpe65(-

31 tion, the ER enzyme glucosidase I (Gls1) was mislocalized and degraded in the vacuole.

32 The SNARE protein Vamp7B was mislocalized and enriched on the contractile vacuoles of

33 e ERM proteins ezrin, radixin, and moesin is mislocalized and found uniformly along the plasma membra

34 n a parAB2 deletion mutant, chromosome II is mislocalized and frequently fails to segregate, yielding

35 In the absence of PARG, SIR2 is mislocalized and hypermodified.

36 In mdx muscle, nNOSbeta was mislocalized and its association with the Golgi complex

37 mutants lacking Schwann cells, the nerve is mislocalized and the axons remain in the epidermis.

38 cytic adaptors known to bind PI(4,5)P(2) are mislocalized and the defects in FM1-43 dye uptake and ad

39 SENP2, we observe that many nucleoporins are mislocalized and, in some cases, reduced in level when S

40 Septins and actin were mislocalized, and cell wall synthesis was very abnormal,

41 nded, pseudopodial activity is increased and mislocalized, and chemotaxis is impaired.

42 the absence of INO80, H2A.Z nucleosomes are mislocalized, and H2A.Z levels at promoters show reduced

43 component of a type III secretion system is mislocalized, and have a severe virulence defect in anim

44 ull mice, PLCbeta2 was undetectable, NHERF-1 mislocalized, and IP3 R3 more intensely stained, along w

45 Furthermore, DAF-6 protein is mislocalized, and lumen morphogenesis is abnormal, in mu

46 of JAM-A, other tight junction proteins were mislocalized, and pseudocanaliculi, which form the apica

47 that the STGD3 truncated mutant may generate mislocalized, and therefore toxic, keto intermediates of

48 apical domains and terminal cells displayed mislocalized apical proteins.

49 tring protein (CSP) and SNAP25, are severely mislocalized at hip14 mutant synapses.

50 he cell wall at physiological pH, but it was mislocalized at low pH.

51 In apm-2 mutants, clathrin is mislocalized at synapses, and synaptic vesicle numbers a

52 ed reduced expression of CD103 (Itgae), were mislocalized away from airway epithelia, and demonstrate

53 E6 attenuates repair by causing RAD51 to be mislocalized away from both transient and persistent DSB

54 se inhibitor (FTI), prelamin A was partially mislocalized away from the nuclear envelope, and the fre

55 structurally weakened nuclei, and emerin is mislocalized away from the nuclear envelope.

56 -eGFP and RhoaCT32-eGFP fusion proteins were mislocalized away from the plasma membrane in embryonic

57 ce of Crumbs or aPKC phosphorylation of Baz, mislocalized Baz recruits adherens junction components a

58 When Fin1 is mislocalized, bipolar spindles fail to assemble but the

59 Expression of mislocalized Bni1p constructs has a dominant-negative ef

60 rains lacking substrates that are toxic when mislocalized, both LolA and LolB can be completely bypas

61 Both Rab8a and Rab10 were mislocalized by the expression of dominant-negative myos

62 abnormal anchorage of radial glial endfeet, mislocalized Cajal-Retzius cells, and neuronal overmigra

63 tion of CLASP2 in migrating neurons leads to mislocalized cells in deeper cortical layers, abnormal p

64 n autoimmune pancreatitis (AIP) by restoring mislocalized CFTR protein to the apical ductal membrane.

65 other than cortical granules suggested that mislocalized csp might sequester a protein that is impor

66 iciently polymerized, resulting in fewer and mislocalized curli fibers.

67 estion, we generated knockin mice expressing mislocalized cytoplasmic FUS and complete FUS knockout m

68 -43 (hTDP-43-WT) to determine the effects of mislocalized cytoplasmic TDP-43 on neuronal viability.

69 s capacity for mesenchymal condensation with mislocalized distributions of chondroitin sulfate proteo

70 FADD-D protein is also mislocalized during cell cycle progression.

71 In summary, we demonstrate that claudin-7 is mislocalized during the malignant transformation of esop

72 ly, however, these patch mutations result in mislocalized exocyst complexes that remain intact.

73 increased expression of aquaporin-2 mRNA but mislocalized expression of aquaporin-2 protein in the cy

74 Furthermore, mislocalized expression of neuroligin-2 disperses postsy

75 ce of the nucleation machinery, resulting in mislocalized fibers.

76 mplified, mRNA overexpressed, and protein is mislocalized from cell-cell junctions in human breast ca

77 Pathological TDP-43 is mislocalized from its nuclear location to the cytoplasm,

78 the remaining alpha- and beta-subunits were mislocalized from the light-sensitive outer segment comp

79 BAF missense mutant S4E, but not S4A, emerin mislocalized from the nuclear envelope, suggesting Ser-4

80 Lastly, Scribble was mislocalized from TJs and its expression down-regulated

81 We propose that branching begins when mislocalized FtsZ triggers the insertion of inert peptid

82 Aurora B normalization redirects the mislocalized furrow proteins to their proper location, c

83 Aggregation of mislocalized FUS into non-amyloid inclusions is believed

84 and mRNA splicing patterns, indicating that mislocalized FUS results in loss of its normal function.

85 Rock inhibition increased the generation of mislocalized ganglion/amacrine cells at the expense of r

86 ncoded by 44 TetO(7)-orf strains resulted in mislocalized GFP-Nic96.

87 Separase is also overexpressed and mislocalized in a wide range of human cancers, including

88 Both Nogo and NgR are mislocalized in AD brain samples.

89 Nups were mislocalized in adult intestinal nuclei and in embryos f

90 naptic ribbon protein, was less abundant and mislocalized in adult wud mutants.

91 re, PKCiota protein is markedly increased or mislocalized in all serous ovarian cancers.

92 NA processing, are abnormally aggregated and mislocalized in ALS and FTLD, while the expansion in the

93 microtubules and is hyperphosphorylated and mislocalized in Alzheimer's disease.

94 eoblast stem cells and progenitor cells were mislocalized in beta1-integrin(RNAi) animals without sig

95 n-1 loss-of-function (lf) mutants, SLO-1 was mislocalized in body-wall muscle but its transcription a

96 likely conserved substrate of fly CCT and is mislocalized in both cct and in dfmr1 mutant embryos.

97 d, an apically localized adaptor protein, is mislocalized in both crb mutant cells and Crb overexpres

98 ronal progenitors, becomes overexpressed and mislocalized in cancer cells from a variety of human tum

99 Strikingly, OGT is mislocalized in cardiac mitochondria from diabetic rats.

100 reduced and, additionally, Sir proteins are mislocalized in cells lacking CAF-1 and Rtt106p.

101 mannosyltransferases, Och1p and Mnn1p, were mislocalized in cog3-202 cells.

102 Pma1p was not mislocalized in concanamycin-treated cells, but a signif

103 the key lipid metabolizing enzyme, lipin, is mislocalized in dTorsin-KO cells, and dTorsin increases

104 Ent3p was mislocalized in Gga-deficient but not in AP-1-deficient

105 ivated these proteins, and mutant human Int6 mislocalized in HeLa cells.

106 n ligase activity towards dysbindin and were mislocalized in heterologous cells.

107 xpression is either decreased or the protein mislocalized in human HCC.

108 EGF receptor is overexpressed and mislocalized in jck cystic epithelia, a hallmark of huma

109 t germ cell nuclei, nucleoporins (Nups) were mislocalized in large plaques beginning at meiotic entry

110 he nuclear envelope protein emerin, which is mislocalized in Lmna mutant cells and also linked to EDM

111 40 and connexin 43 were misexpressed and/or mislocalized in LmnaN195K/N195K hearts.

112 (NIS; aka SLC5A5), which is upregulated and mislocalized in many human carcinomas.

113 nd a recently identified Chk1 substrate, was mislocalized in mitotic Chk1(+/-) mammary epithelia.

114 of the mutants were transport-competent but mislocalized in mouse liver.

115 luR localization are also grossly reduced or mislocalized in mtg mutants, including the dPix-dPak-Doc

116 nstrated that viral capsids assemble but are mislocalized in nuclei of cells infected with the mutant

117 NUP-1 is mislocalized in NUP-2 knockdown cells and vice versa, im

118 Moreover, the KASH protein ZYG-12 was mislocalized in ooc-5 gonads.

119 polycystin-2, a protein involved in PKD, is mislocalized in orpk mice.

120 The exocyst complex was also found to be mislocalized in PALS1 knockdown cells, potentially expla

121 ylated rod PDE6 catalytic subunits partially mislocalized in Pde6d(-/-) rods, whereas rhodopsin was u

122 ulator of rhodopsin ciliary trafficking, was mislocalized in photoreceptor cells of rpgrip1 mutants.

123 orm layer over drusen, synaptic proteins are mislocalized in photoreceptor cells, and synaptic termin

124 Here we demonstrate that NF-E2 is mislocalized in PMF cells and that aberrant NF-E2 locali

125 is, the cortical actin patch protein Sla2 is mislocalized in sjl1Delta sjl2Delta mutant cells.

126 Mad2 is mislocalized in Smurf2-depleted cells, suggesting that S

127 spatial regulator of MSP disassembly, MSP is mislocalized in sperm lacking GSP-3/4.

128 main myristoylated kinases in T cells, were mislocalized in the absence of Nmt activity.

129 that HCV replication complex components were mislocalized in the AH-disrupted mutant.

130 , endothelial cells with venous identity are mislocalized in the aorta, suggesting that ephrin B2/Eph

131 the cytoskeleton protein betaII spectrin are mislocalized in the axon, and assembly of the node of Ra

132 ted to the nucleus, but mutant isoforms were mislocalized in the cytoplasm.

133 These proteins can be mislocalized in the cytosol due to mutations in their ta

134 nts, when tactile stimuli are systematically mislocalized in the direction of the movement.

135 Mutant receptor tyrosine kinases are mislocalized in the endoplasmic reticulum (ER) of AML an

136 ochlea in vivo; however, tricellulin becomes mislocalized in the inner ear sensory epithelia of ILDR1

137 l stem cell proliferation, was increased and mislocalized in the intestinal epithelia of the beta1 in

138 that, in Myo7a-mutant mice, RPE65 is partly mislocalized in the light.

139 ted in Rs1-KO, and some PSD95 and mGluR6 was mislocalized in the outer nuclear layer (ONL).

140 Moreover, the tight junction protein ZO-1 is mislocalized in the tal1-deficient endocardium, indicati

141 Laminin is mislocalized in this mutant, as are the membrane-associa

142 ane cell fate regulator, SCRAMBLED (SCM), is mislocalized in ugt80B1 mutants, underscoring the aberra

143 Pma1p is mislocalized in vma mutants but remains at the plasma me

144 hese transgenic rods without chromophore was mislocalized; in R-opsin's presence, however, S-opsin tr

145 Interestingly, the 26S proteasome is mislocalized into foci, which are colocalized with nucle

146 contraction begins, MYO-3 and UNC-89 become mislocalized into large foci and animals die.

147 Here, we show that overexpressed CID is mislocalized into normally noncentromeric regions in Dro

148 However, Vps34-deficient T cells have mislocalized intracellular Eea1, HGF-regulated tyrosine

149 isplay defective cell polarity, resulting in mislocalized junctional complexes and loss of adhesion t

150 ing of this repeat peptide into erythrocytes mislocalized KAHRP in the parasitized cells.

151 Silencing of GPR31 expression partially mislocalized KRAS4B, slowed the growth of KRAS-dependent

152 of nodes, disrupted paranodal junctions, and mislocalized Kv1 K(+) channels.

153 ress response pathways that are activated by mislocalized lipopolysaccharide may collectively contrib

154 unction is to prevent lethal accumulation of mislocalized lipoproteins.

155 ficking tasked with protecting the cell from mislocalized lipoproteins.

156 opsins mistrafficked as reported previously, mislocalized M-opsin was degraded whereas mislocalized S

157 , Ubr4 is responsible for the degradation of mislocalized MEC-2 multimers.

158 , UBQLN1 plays an important role in clearing mislocalized mitochondrial proteins upon cell stimulatio

159 sitioned centrosomes and Golgi apparatus and mislocalized molecules of the slit diaphragm.

160 ifically alters EC directional migration and mislocalized MT organizing center (MTOC)/Golgi and myosi

161 On the other, the mislocalized mutant PTEN results in a significantly decr

162 Expression of mislocalized mutant syntaxin 3 in Madin-Darby canine kid

163 ociated with previously characterized matrix-mislocalized-mutant tafazzins to include the rapid degra

164 A activity resulting, in part, from severely mislocalized myospryn and the type II regulatory subunit

165 layer of the spinal cord of Dcc-/- mutants, mislocalized neurons are followed by proprioceptive affe

166 ivo, dysferlin null muscle was found to have mislocalized nuclei and vacuolation.

167 otably, all types of defective spindles have mislocalized NuMA (nuclear mitotic apparatus protein), a

168 topes abolishes binding to the karyopherins, mislocalized NXF1 to the cytoplasm, and significantly co

169 sin-2, a major anterograde IFT motor, causes mislocalized opsin, followed by rapid cell death.

170 t likely results secondarily from binding to mislocalized opsin.

171 Immunofluorescence correctly identified mislocalized or absent staining in 100% of the discovery

172 , localizing to the position of PGCs whether mislocalized or trapped in the endoderm.

173 pole plasm posteriorly and in degrading any mislocalized Oskar that results from leaky translational

174 (Psp) stress response system is activated by mislocalized outer-membrane secretin components of prote

175 SS2 expression was increased and the protein mislocalized over the entire tumor cell membrane.

176 spadias is a urethral tube defect defined by mislocalized, oversized, or multiple openings of the pen

177 ell morphology, blocked cell retraction, and mislocalized Pak, producing uropod (tail-like) structure

178 tablishing its function as release factor of mislocalized palmitoylated proteins in the acylation cyc

179 protein thioesterases (APTs) depalmitoylate mislocalized palmitoylated proteins on endomembranes.

180 Surprisingly, these mislocalized PCs did not maintain adjacent zymogenic lin

181 Ror2 and Wnt5a mutants with mislocalized PGCs corroborate the microenvironmental reg

182 ed two green fluorescent protein (GFP)-fused mislocalized PGK mutants, the transit peptide deletion m

183 dysregulation of Numb expression results in mislocalized Plk1 and poor centrosomal gamma-tubulin rec

184 The majority of the mislocalized PMCs in miR-31 KD embryos did not express V

185 ion formation as evidenced by loss of Caspr, mislocalized potassium Kv1.2 channels, and abnormal myel

186 ing to ineffective H2AX dephosphorylation by mislocalized PP4c phosphatase rather than ongoing DNA da

187 A FTI also mislocalized prelamin A and improved nuclear shape in Zm

188 the population of prefrontal neurons grossly mislocalized presaccadic stimuli as being closer to the

189 The farnesyltransferase inhibitor mislocalized progerin away from the nuclear envelope to

190 The mechanisms of mislocalized protein (MLP) degradation are unknown.

191 hown to be important in the TRC pathway, the mislocalized protein degradation pathway, and the endopl

192 sults in a specific stabilization of a model mislocalized protein derived from the amyloid precursor

193 d demonstrate the importance of accumulating mislocalized protein per se, rather than specific signal

194 ese data reveal that, in a cellular context, mislocalized protein ubiquitination is the result of a d

195 xposed hydrophobic transmembrane domain of a mislocalized protein, thereby preventing BAG6 recruitmen

196 Mislocalized proteins (MLPs) are protected from aggregat

197 Mislocalized proteins bearing a signal sequence that did

198 wn to enhance the proteasomal degradation of mislocalized proteins by selectively promoting their ubi

199 (fs) mutations that encode DNase-active but mislocalized proteins cause disease.

200 ow that the BAG6-dependent ubiquitination of mislocalized proteins is completely reversible and ident

201 TA actively promotes the deubiquitination of mislocalized proteins that are already covalently modifi

202 t, repair, or hydrolyze mutant, damaged, and mislocalized proteins.

203 n a polarized morphology, but instead extend mislocalized pseudopodia around the cell and exhibit dec

204 ity occurred in cells expressing the nuclear mislocalized PTEN-K62R mutant, whereas elevated cytosoli

205 r subset of cases with an unusual pattern of mislocalized punctate MHC II staining and intermediate l

206 AFC mislocalized Rac1, both from the plasma membrane and the

207 Indeed, cytoplasmically mislocalized RB could be efficiently confined to the nuc

208 Cytoplasmically mislocalized RB could be efficiently confined to the nuc

209 In the absence of the VXPX motif, mislocalized rhodopsin is actively cleared through secre

210 ciliary membrane projections that accumulate mislocalized rhodopsin.

211 indings thus describe a novel link between a mislocalized RNA binding protein implicated in ALS (RBM4

212 We propose that in retinal disease, mislocalized rod opsin gains access to cAMP signaling, w

213 y, mislocalized M-opsin was degraded whereas mislocalized S-opsin accumulated in Lrat(-)(/-) cones be

214 We found that mislocalized scaffolding by the plasma membrane Na-H exc

215 Thus, we demonstrate that high levels of mislocalized SCRIB functions as a neomorph to promote ma

216 ce and humans possess both downregulated and mislocalized Scribble.

217 Mislocalized secretins induce psp gene expression, and k

218 serving as a sensor of DNA from pathogens or mislocalized self-DNA.

219 ions and eliminating the need for washout of mislocalized sensor.

220 n results in unstable dendritic protrusions, mislocalized shaft-synapses, and loss of compartmentaliz

221 iosis I, leading to monopolar, multiple, and mislocalized spindles.

222 reduced growth rate, cell filamentation, and mislocalized stalks.

223 During replication stress, the mislocalized Stn1 may inappropriately promote Pol alpha

224 ular basement membrane marker collagen IV is mislocalized, suggesting that ECs fail to recognize the

225 also appear when the septal protein FtsZ is mislocalized, suggesting that peptidoglycan modification

226 icroscopy revealed that the cone opsins were mislocalized, suggesting that their transport to the out

227 upled to pervasive incorporation of H2A.Z by mislocalized SWR-C alters chromatin composition and cont

228 processes into the outer nuclear layer, and mislocalized synaptic complexes.

229 r framework for Msp1-dependent extraction of mislocalized TA proteins from the outer mitochondrial me

230 AAA+ ATPase Msp1 limits the accumulation of mislocalized TA proteins on mitochondria.

231 ht promote the extraction and degradation of mislocalized TA proteins to maintain mitochondrial integ

232 Likely as a result of failing to extract mislocalized TA proteins, yeast with combined mutation o

233 Mislocalized tail-anchored (TA) proteins of the outer mi

234 We find that the mislocalized telomeres of ctf18 cells still replicate la

235 matin, abnormally clustered centromeres, and mislocalized telomeres.

236 tion of 4.1 disrupted microtubule arrays and mislocalized the spindle pole protein NuMA.

237 Once mislocalized, they are recognized by the Hsp70 chaperone

238 Two distinct truncating mutants were mislocalized throughout the axon and phenocopied the arr

239 ociated proteins, lamin A/C and emerin, were mislocalized throughout the nucleoplasm.

240 ataxia-telangiectasia mutated and Chk2, are mislocalized to a cytoplasmic virus assembly zone, where

241 and shape, and septate junction proteins are mislocalized to a more apical position.

242 t SAMHD1 mutants of the cyclin-binding motif mislocalized to a nuclear compartment and had reduced ab

243 Cx32 was mislocalized to an intracellular location in hepatocytes

244 abundant in the basolateral membrane and was mislocalized to apical bundles in ap1b1 mutant hair cell

245 ancer cell lines and that this active PAK is mislocalized to atypical focal adhesions in the absence

246 pindle pole body (SPB), Kar9p-L304P-3GFP was mislocalized to both SPBs.

247 lls express low levels of E-cadherin that is mislocalized to cytoplasmic vesicles.

248 -33 and unc-44 mutants, axonal proteins were mislocalized to dendrites and vice versa, suggesting bid

249 percentage of C150S-Rds and cone opsins were mislocalized to different cellular compartments in cones

250 tissues, Cx43 was found to be pathologically mislocalized to lateral sides of cardiomyocytes.

251 owed both glyphosate sensitivity and FD5-GFP mislocalized to nuclei.

252 mentia (FTD) cases, and LSD1 is specifically mislocalized to pathological protein aggregates in these

253 assembled at ectopic locations, and TipF is mislocalized to such sites.

254 During mitosis, Pins is mislocalized to the apical surface in the absence of Par

255 ish Clrn1; in contrast, hCLRN1(N48K) largely mislocalized to the cell body with a small amount reachi

256 e N-terminal 15 amino acids caused MP1 to be mislocalized to the cytoplasm and nucleus.

257 have found that the viral DNA polymerase is mislocalized to the cytoplasm in both infected and trans

258 tochemical analysis also showed that p27 was mislocalized to the cytoplasm in the majority of osteosa

259 Ect2 is overexpressed and mislocalized to the cytoplasm of NSCLC cells where it bi

260 In NSCLC cells, Ect2 is mislocalized to the cytoplasm where it binds the PKCiota

261 6 variant proteins KLF6-SV1 and KLF6-SV2 are mislocalized to the cytoplasm, antagonize wtKLF6 functio

262 addition, FSGS-linked ACTN4 mutants not only mislocalized to the cytoplasm, but also lost their abili

263 These results suggest that mutant TDP-43 is mislocalized to the cytoplasm, where it exhibits a toxic

264 aroid and nuclear pore complex proteins were mislocalized to the cytoplasm.

265 W-E) in complex with CDK2 are preferentially mislocalized to the cytoplasm.

266 oteinopathies, in which this protein becomes mislocalized to the cytoplasm; however, it is unclear wh

267 PTS-1 directed the synthesis of an arg that mislocalized to the cytosol and notably also complemente

268 ICL and thiolase were mislocalized to the cytosol but only ICL was stabilized

269 ized to peroxisomes in 4-d-old seedlings but mislocalized to the cytosol in 8-d-old seedlings.

270 CTR1 was similarly mislocalized to the cytosol in the heart of knockin mice

271 cases of Alzheimer disease it is cleaved and mislocalized to the cytosol, leading to accumulation.

272 en though glycosomal proteins continue to be mislocalized to the cytosol.

273 aN13) lacking the first 13 residues was also mislocalized to the endoplasmic reticulum although it re

274 ations present in the stem domain of POMGnT1 mislocalized to the endoplasmic reticulum, highlighting

275 ues) exhibited undetectable activity and was mislocalized to the endoplasmic reticulum, suggesting th

276 Further, mutant receptors were mislocalized to the inner segments and perinuclear regio

277 and the gap junction protein connexin 43 was mislocalized to the lateral myocyte border.

278 ly reduced in diabetic samples, where OGT is mislocalized to the matrix.

279 he tissues of these mice would be strikingly mislocalized to the nucleoplasm, but this was not the ca

280 ytoplasmic intermediate filament network and mislocalized to the nucleus.

281 In addition, cone opsin mislocalized to the outer nuclear layer and the outer pl

282 calizing in the adjacent juxtaparanode, were mislocalized to the paranode.

283 articularly prominent with OspC mutants that mislocalized to the periplasm or contained C-terminal ep

284 Furthermore, a Ctr2 mutant that is mislocalized to the plasma membrane stimulates extracell

285 otably, opsin stimulated sprouting only when mislocalized to the plasmalemma of the rod cell body.

286 We previously reported that XPA mislocalized to the progerin-induced DNA double-strand b

287 y injury to other peripheral axons that were mislocalized to the skin, neighboring skin cells, and ma

288 ouse line) exhibited hyperphosphorylated tau mislocalized to the somatodentritic domain of neurons, b

289 ition was increased in lrg1Delta strains and mislocalized to the tip of the mating projection in fus2

290 D1 (PIN1), PIN2, and AUXIN-RESISTANT1 (AUX1) mislocalized to the vacuolar membrane of the mutant.

291 ubuloreticular and sarcolemmal membranes and mislocalized triads and mitochondria in skeletal muscle

292 DP-25 and TDP-35 and that protection against mislocalized/truncated TDP-43 was observed for HSPB8 in

293 Two of these mislocalized variants (W59R and I149del) also showed an

294 Mislocalized Wee1B or Myt1 is not able to maintain meiot

295 th either TRPML1 or TRPML2 and is comparably mislocalized when lysosomal targeting of TRPML1 and TRPM

296 anGAP protein is enzymatically wild type but mislocalized within cells and, for reasons that remain u

297 RAD-23 abundance is increased and RAD-23 is mislocalized within motor neurons.

298 which are null for lamins A/C, LAP2alpha is mislocalized within nuclear aggregates, and this is corr

299 PRX lacking O-GlcNAcylation is mislocalized within the myelin sheath of these mutant an

300 es is unavailable because lipid droplets are mislocalized, zygotic histone production starts prematur