ライフサイエンスコーパス: mismatch

1 pdated trajectory and sequenced information (mismatch).

2 ed criterion donor kidney, and number of HLA mismatches).

3 ificant after adjustment for HLA-DR/DQ eplet mismatch.

4 re dependent on the molecular species of the mismatch.

5 ubunits to bridge gaps created by the number mismatch.

6 a 27-mer DNA duplex containing a central CC mismatch.

7 rd lower yields presumably due to a polarity mismatch.

8 of the closed PIN state with a UUG-anticodon mismatch.

9 s in order to elucidate the role of symmetry mismatch.

10 inizes the origin of this structure-function mismatch.

11 their substrate due to delithiation-induced mismatch.

12 webs through a mechanism other than trophic mismatch.

13 evelopment in the context of HLA-DR/DQ eplet mismatch.

14 be controlled by the temperature and lattice mismatch.

15 to quasi-1D, leading to strong Fermi surface mismatch.

16 oimmune risk determined by HLA-DR/DQ epitope mismatch.

17 retino-collicular map, creating a visuotopic mismatch.

18 No improvement occurred when frequencies mismatched.

19 ikely to reject (p = 0.01) compared with H-Y mismatches.

20 ries different densities of single-base-pair mismatches.

21 ample detected 16 resolved sequences with no mismatches.

22 entration, PNA concentration, and DNA strand mismatches.

23 elated HCT is predominantly an effect of HLA-mismatching.

24 is compact structure by an electrostatically mismatched A86K mutation profoundly affected the DNA bin

25 e imperfections, such as single and multiple mismatches, abasic sites, and single nucleotide insertio

26 ed multiple minor histocompatibility antigen-mismatched alloHCT using bone marrow (BM) cells and sple

27 ids to half the value predicted from lattice mismatch alone.

28 Mismatch and base-excision repair are important in the s

29 ns is challenging because their high lattice mismatch and different thermal expansion coefficients ca

30 Both mismatch and fluctuations decrease the size of the preor

31 are at increased risk for prosthesis-patient mismatch and impaired outcomes.

32 ference in rate of VOCE between the negative mismatch and negative concordance groups (FFR>0.80; haza

33 We conclude that HLA-DR/DQ eplet mismatch and tacrolimus trough levels are independent pr

34 rovided by specificity analysis using single mismatched and complementary oligonucleotide sequences.

35 find a correlation between frequency tuning mismatches and best ITDs.

36 ide position-dependent sensitivity to single mismatches and the reduction of off-target cutting using

37 fficiently by ADAR deaminase domains at dA-C mismatches and with E to Q mutations in the base flippin

38 leotides over single-base-mismatch, two-base-mismatch, and noncomplementary DNA targets.

39 ecipients, including 125 cord blood, 125 HLA-mismatched, and 154 HLA-matched HCTs, detection of multi

40 between complementary, single-, doubled-base mismatched, and non-complementary targets.

41 1 is tolerant of single mismatches, multiple mismatches, and even abasic sites, whereas RecA and Rad5

42 ues ranging from about 100 Omega mum for low-mismatch angles in Class-I (symmetric) interfaces to 10(

43 e of GBs, starting from 53 Omega mum for low-mismatch angles in twin (symmetric) GBs to about 10(20)

44 Bs, ranging from about 130 Omega mum for low mismatch angles to about 6000 Omega mum for 21 degrees .

45 asymmetric GBs show a gradual dependence on mismatch angles.

46 Fourth, sequences aligned to miRNAs with mismatches are remapped to a reference genome to further

47 These mismatches are usually mitigated either by the model dyn

48 utcomes in the group of patients with target mismatch as identified with advanced imaging.

49 In both a minor histocompatibility antigen-mismatched as well as a MHC-haploidentical model of scle

50 tween transplantations that were matched and mismatched at one allele (HR 1.18, 95% CI 0.80-1.72, p=0

51 model for Cas9 specificity wherein gRNA-DNA mismatches at PAM-distal bases modulate different biophy

52 ExoN excises nucleotide mismatches at the RNA 3'-end in vitro, and its inactivat

53 mainly include DNAzymes, G-quadruplexes, and mismatched base pairs and nanomaterials cover gold nanop

54 iniscent of DNA repair enzymes that displace mismatched bases, and is differentiated from other DNA-t

55 he membrane monolayers causes a surface area mismatch between both monolayers, which leads to vesicle

56 t 2014-2015 influenza season, when antigenic mismatch between circulating and vaccine influenza strai

57 thological diagnosis in older adults and the mismatch between clinical and neuropathological diagnose

58 be well 6 to 24 hours earlier and who had a mismatch between clinical deficit and infarct, outcomes

59 A mismatch between developmental changes and social/enviro

60 TP channel inhibition probably exacerbates a mismatch between energy demand and energy production whe

61 Mismatch between environmental filtering (the most data-

62 propose a model in which the conformational mismatch between free V1 and Vo functions to prevent uni

63 causes the greatest increase in hydrophobic mismatch between liquid-ordered (Lo) and Ld domains amon

64 A mismatch between modelling predictions and the experimen

65 In Ethiopia, there is a substantial mismatch between need and supply of corneal transplant.

66 solvent water molecules, we find that energy mismatch between occupied orbitals of both the solutes N

67 The detection of a mismatch between our predictions and what actually happe

68 whereas type 2 MIs occur in the setting of a mismatch between oxygen demand and supply, as with sever

69 The current mismatch between postindustrial hygienic lifestyles and

70 s work or school, artificial light induces a mismatch between sleep timing and circadian rhythmicity

71 f optical aberration due to refractive index mismatch between the fluid and the device walls.

72 nterface arises from strain based on lattice mismatch between the GaAs and ALD-deposited aluminum oxi

73 -order phase transition with a large lattice mismatch between the involved phases, spinel LiMn1.5Ni0.

74 this modified model reduces a long-standing mismatch between the modeled and observed seasonal ampli

75 be well 6 to 24 hours earlier and who had a mismatch between the severity of the clinical deficit an

76 ilizing the thermal coefficient of expansion mismatch between the substrate and semiconductor.

77 nd leaf reflectance and secondarily from the mismatch between the vertical distribution of leaf nitro

78 ergetically unfavorable residual hydrophobic mismatch between TM4 and the membrane, reducing the driv

79 Mismatches between donor and patient in these alleles ar

80 ensively assess the effects of combinatorial mismatches between guide RNA (gRNA) and target nucleotid

81 and environmental change can cause temporal mismatches between interacting species, and thereby impa

82 In light microscopy, refractive index mismatches between media and sample cause spherical aber

83 Mismatches between the TB&S and kmer ID results were exp

84 by rapid antigenic drift, which can lead to mismatches between vaccine strains and circulating strai

85 ative to the large difference in genome-wide mismatching between the 2 groups.

86 a widely applicable clinical tool, and the "mismatch" between perfusion-weighted and diffusion-weigh

87 tioning and major histocompatibility complex mismatched BMT with or without Treg cell infusion.

88 ed major histocompatibility complex class II mismatched C57BL/6N (H-2; B6) or B6.RIP3 (H-2; RIP3) mic

89 In contrast, we observe that binocularly mismatched cells are more mismatched in orientation tuni

90 vity of neurons only from the same region in mismatched cocultures, exhibiting region-matched astrocy

91 ed Tl2O bulk, and has a very small interface mismatch compared to (001) Tl metal.

92 n structure correct phase and group-velocity mismatches concurrently.

93 th of epitaxial nanocomposites using lattice-mismatched constituents also enables strain-engineering,

94 Nearly all mismatch correction depends on the proofreading activity

95 Mismatch correction of strand invasion heteroduplex DNA

96 d MutL protein families perform key steps in mismatch correction.

97 higher degrees of genome-wide recipient GVH mismatching correlate with higher risks of GVHD after al

98 This global mismatch could be reversed, however, by placing new mari

99 Simulations using 46 ICPs and 11 fully HLA-mismatched CPs were undertaken using the Australian KPD

100 linical deficit and the infarct volume, with mismatch criteria defined according to age (<80 years or

101 Patients meeting target mismatch criteria were analyzed as a subgroup to identif

102 tacrolimus trough levels had HLA-DR/DQ eplet mismatch determined using HLAMatchmaker software.

103 liably quantified with excellent single-base-mismatch differentiation capability by this non-enzymati

104 rostatically repel the non-complementary and mismatch DNA sequences, overcoming the non-specific bind

105 after the first MVA-CMDR boost, the sequence-mismatched DNA-prime MVA-boost vaccine strategy induced

106 andidates but also to identify more suitably mismatched donors for nonsensitized patients.

107 As a result, some of the mismatch duplexes are more stable than some of the seque

108 However, the most stable mismatch duplexes contain DDD and compete with the most

109 Mismatched duplexes that have an excess of H-bond donors

110 The lifetime of POLRMT on terminally mismatched elongation substrate is increased in the pres

111 logous G-G mismatch (or sometimes also a G-A mismatch) enhances target slicing, despite disrupting se

112 Evidence is summarized how mismatched eplet loads affect antibody responses and tra

113 BMT options include unrelated cord blood or mismatched family donors.

114 mismatch (FFR</=0.80; DS<50%), and negative mismatch (FFR>0.80; DS>/=50%).

115 ive concordance (FFR>0.80; DS<50%), positive mismatch (FFR</=0.80; DS<50%), and negative mismatch (FF

116 attice mismatch for 3 uc of BTO and symmetry mismatch for 10 uc of BTO, both associated with local Mn

117 Lattice mismatch for 3 uc of BTO and symmetry mismatch for 10 uc

118 dal listening; IE was sensitive to tonotopic mismatch for EAS, but not for bimodal listening.

119 been applied not only to identify acceptable mismatches for sensitized transplant candidates but also

120 sociated with an immune response against MHC-mismatched grafted cells.

121 positive mismatch group than in the negative mismatch group (hazard ratio, 0.38; 95% confidence inter

122 The rate of VOCE was higher in the positive mismatch group than in the negative mismatch group (haza

123 etween the positive concordance and positive mismatch groups (FFR</=0.80; hazard ratio, 0.77; 95% con

124 E. coli and that, while all MutS-recognized mismatches had been thought to be repaired in a consiste

125 multiple viruses included cord blood or HLA-mismatched HCT, myeloablative conditioning, and acute gr

126 transplantation of a minor antigen (HY) sex-mismatched heart graft, the lymphatic flow index was sig

127 vior among three sets of monomers possessing mismatched host-guest pairs.

128 vior among three sets of monomers possessing mismatched host-guest pairs.

129 he decreased melting temperature of the tL.C mismatched hybrid as compared to that of the t.C mismatc

130 atched hybrid as compared to that of the t.C mismatched hybrid, while the melting temperatures of the

131 We tested this thermal mismatch hypothesis by quantifying the temperature-depen

132 pectively, providing support for the thermal mismatch hypothesis.

133 Patients were classified as "target mismatch" if they had a small ischemic core and a large

134 nterfaces to 10(15) Omega mum for 14 degrees mismatch in Class-II (asymmetric) interfaces.

135 In 90% of the high-grade TRAMP tumors, a mismatch in perfusion and metabolism measurements was ob

136 cies but, surprisingly, also for a syngeneic mismatch in sex.

137 d signal intensity not only for a xenogeneic mismatch in species but, surprisingly, also for a syngen

138 Generating a single base mismatch in the growing primer duplex, which attenuates

139 GBs to about 10(20) Omega mum for 21 degrees mismatch in tilt (asymmetric) GBs.

140 e that binocularly mismatched cells are more mismatched in orientation tuning.

141 recently showed that wobble dG.dT and rG.rU mismatches in DNA and RNA duplexes transiently form taut

142 investigated the relation between interaural mismatches in frequency tuning and ITD tuning during in

143 Mismatches in HLA-DRB3, 4, and 5 are usually not taken i

144 es in thalamus and cortex generate frequency mismatches in inter-regional connectivity, leading to a

145 se pairs to discriminate against DNA and RNA mismatches in order to ensure high fidelity replication,

146 fficiency, which can be affected by sequence mismatches in primer/probe binding regions, RT-dPCR may

147 ially important consequences for remediating mismatches in the thylakoid energy budget.

148 of this ligand may lead to improved KIR-HLA mismatching in hematopoietic stem cell transplantation t

149 nt HEV sequences with significant nucleotide mismatching in primer/probe binding regions, while evalu

150 ithin-population variance) to the phenotypic mismatch (inaccuracy) of heterostylous morphs on a commo

151 ial to multi-millennial timescales, with the mismatch increasing for longer periods.

152 ubstrate including catalysis effect, lattice-mismatch-induced strain, and roughness, and growth condi

153 HLA-DQ mismatch is a significant risk factor for de novo DSA em

154 The mismatch is held at the latch constriction of alpha-hemo

155 However, the thermal mismatch is not completely resolved in highly mismatched

156 Thus, how detection of U:G mismatches is translated into the single-strand nick req

157 sponse and transplant tolerance induction to mismatched islet allografts.

158 kernels, based on the recently described di-mismatch kernel.

159 owever, when two Y-STR haplotypes have a few mismatched loci, it is difficult to determine if they ar

160 H-Y antigen mismatched (M-->F) patients were at greater risk of reje

161 ined NGS data and we observed two additional mismatches made up of minority variants (7% and 18%) tha

162 H-Y mismatched (male [M]-->female [F]) corneas were at great

163 Heteroepitaxial growth of lattice mismatched materials has advanced through the epitaxy of

164 as model antigens for clinically permissive mismatches mediating limited T-cell alloreactivity with

165 al models using refractive index matched and mismatched microscope objectives.

166 n this commentary, I explore why research on mismatch might be called into question by changing views

167 We examined whether amino acid (AA) mismatches (MMs) at the antigen recognition site of HLA

168 ngent major histocompatibility complex fully mismatched mouse models were used to evaluate the alloim

169 ings suggest that Dmc1 is tolerant of single mismatches, multiple mismatches, and even abasic sites,

170 ted significantly improved discrimination of mismatched (mutant) alleles from matched (wild-type) all

171 air as a latent endonuclease that requires a mismatch, MutSalpha/beta, and DNA-loaded proliferating c

172 Deficits in the generation of auditory mismatch negativity (MMN) generation are among the most

173 ormation processing: prepulse inhibition and mismatch negativity (MMN) in SZ patients and healthy sub

174 Mismatch negativity (MMN) indexes pre-attentive informat

175 ients who had developed PTSD showed enhanced mismatch negativity (MMN), increased theta power (5-7 Hz

176 stablished index of auditory perception, the mismatch negativity response, tested whether the therapi

177 Main Outcome and Measures: Mismatch negativity, P3a, and reorienting negativity wer

178 ng the proportions of reacting peptides with mismatched numbers of complementary reactive groups resu

179 nthetase (SepRS) catalyzes the ligation of a mismatching O-phosphoserine (Sep) to tRNA(Cys) followed

180 Mismatch occurs when there is a discrepancy between prod

181 e find that repair of genomic lagging strand mismatches occurs bi-directionally in E. coli and that,

182 In this work, the effect of lattice mismatch of CdS/ZnS core/shell QDs on Mn(II) dopant beha

183 This pattern explained a phenological mismatch of nesting with hydrological conditions, whereb

184 it a Moire superstructure due to the lattice mismatch of Pb and IrTe2, which produces strong lateral

185 eneration and can be tuned by group-velocity mismatch of the pump fields.

186 unrelated recipients, the average recipient mismatching of coding SNPs was 17.3%.

187 ed sibling recipients, the average recipient mismatching of coding SNPs was 9.35%.

188 1.9 (1.3; 3.2), ASO 25mg/kg: 2.8 (0.7; 5.0), mismatch oligonucleotide (MM) 25mg/kg: 5.7 (5,0; 5.8), s

189 The impact of HLA mismatches on graft survival was analyzed and survival r

190 reliance on social learning can also lead to mismatched or maladaptive behavior.

191 reased its capacity to remove G/T nucleotide mismatches or 5-formylcytosine.

192 An analogous G-G mismatch (or sometimes also a G-A mismatch) enhances tar

193 nor-derived target cells transduced with the mismatched patient variant HLA-DRB3 and HLA-DPB1 molecul

194 After transplant, 3 (25%) of 12 HHV8-mismatch patients (seropositive donor/seronegative recip

195 In strains lacking MMR, the mismatches persist.

196 ion with isothermal DNA amplification, using mismatched primers in conjunction with a two-round enric

197 ncluding SNPs with wrong RS ID and SNPs with mismatched probe sequences.

198 to recombination hotspots, independently of mismatch recognition.

199 with myeloid malignancy and those receiving mismatched related/haploidentical grafts, were 80% (+/-6

200 Mismatch repair (MMR) deficiency (MMRD) and microsatelli

201 ention efforts, including: tumor testing for mismatch repair (MMR) deficiency in Lynch syndrome estab

202 cause of a germline mutation in one of their mismatch repair (MMR) genes.

203 ying a pathogenic germline mutation in three mismatch repair (MMR) genes: MLH1, MSH2, and MSH6.

204 Mismatch repair (MMR) is a conserved mechanism exploited

205 Mismatch repair (MMR) is a near ubiquitous pathway, esse

206 Mismatch repair (MMR) is one of the main systems maintai

207 We aimed to describe a large cohort of mismatch repair (MMR) mutation carriers ascertained thro

208 The DNA mismatch repair (MMR) pathway recognizes and repairs err

209 rocessed by uracil-DNA glycosylase (UNG) and mismatch repair (MMR) pathways to generate mutations at

210 Loss of MutS homolog 2 (MSH2), a mismatch repair (MMR) protein, abrogated early inflammat

211 To determine the association of DNA mismatch repair (MMR) status and somatic mutation in the

212 context, a combination of MGMT activity and mismatch repair (MMR) status of the tumor are important

213 w prognostic score (mGPS), and combined BRAF-mismatch repair (MMR) status.

214 report that MLH1, a key protein involved in mismatch repair (MMR), suppresses telomeric sequence ins

215 , which occur frequently in hypermutated DNA mismatch repair (MMR)-proficient tumors and appear to be

216 selectivity, proofreading activity, and DNA mismatch repair (MMR).

217 and requires base excision repair (BER) and mismatch repair (MMR).

218 yps, tumor microsatellite instability [MSI], mismatch repair [MMR] deficiency) is unknown.

219 1-PMS1 in yeast) functions in early steps of mismatch repair as a latent endonuclease that requires a

220 sistent with the hypothesis of Mlh1-Mlh3 DNA mismatch repair complex acting as the major endonuclease

221 characterized by a nonsense mutation in the mismatch repair component MSH2.

222 Microsatellite instability (MSI) caused by mismatch repair deficiency (dMMR) is detected in a small

223 Therefore, assessing the general impact of mismatch repair deficiency on the likelihood of mutation

224 eviously showed that colorectal cancers with mismatch repair deficiency were sensitive to immune chec

225 ckpoint inhibitor-based regimen because of a mismatch repair gene anomaly are presented.

226 By targeting the DNA mismatch repair gene MLH1 CGI, we could generate a PSC m

227 n accumulation in organoids deficient in the mismatch repair gene MLH1 is driven by replication error

228 Moreover, recent research suggests that DNA mismatch repair gene mutations may facilitate acquisitio

229 yndrome, caused by germline mutations in the mismatch repair genes, is associated with increased canc

230 cluding tumor suppressor, mitochondrial, and mismatch repair genes.

231 n of tumor stroma obscured signatures of DNA mismatch repair identified in cell lines with a hypermut

232 er only weak mutator phenotypes, inactivates mismatch repair in the yeast cell.

233 ained by preferential recruitment of the DNA mismatch repair machinery to a protein modification that

234 hout a protruding nonhomologous 3' tail, the mismatch repair protein Msh2 does not discourage homeolo

235 equire the presence, not the absence, of the mismatch repair protein MutSbeta (Msh2-Msh3 heterodimer)

236 o identify those with dMMR, based on loss of mismatch repair proteins MLH1, MSH2, MSH6, and/or PMS2.

237 tection of biological macromolecules such as mismatch repair proteins through biotinylated DNA substr

238 Here we show that the budding yeast mismatch repair related MutLbeta complex, Mlh1-Mlh2, spe

239 We find thirteen mismatch repair variants of uncertain significance that

240 es: age related, double-strand break repair, mismatch repair, and 1 with unknown etiology (signature

241 ulting distributions of conversion tracts in mismatch repair-deficient and mismatch repair-proficient

242 y of PD-1 blockade in patients with advanced mismatch repair-deficient cancers across 12 different tu

243 he large proportion of mutant neoantigens in mismatch repair-deficient cancers make them sensitive to

244 ely models the mutation profiles observed in mismatch repair-deficient colorectal cancers.

245 sion tracts in mismatch repair-deficient and mismatch repair-proficient strains.

246 a ATPase, and MutLalpha function in in vitro mismatch repair.

247 ded DNA gaps and/or involve Mlh1-independent mismatch repair.

248 With every sixth base pair mismatched, repair was still more than 5%.

249 in the control group) of Chinese children's Mismatch Responses (MMRs) to equivalent pitch deviations

250 integration of beliefs about the world with mismatches resulting from the comparison of these belief

251 ons with the 27-mer duplex containing the CC mismatch reveal a DNA binding affinity of 3.1 x 10(6) M(

252 Recipients with a high-risk HLA eplet mismatch score were less likely to tolerate low tacrolim

253 As long as validation of the mismatch selection paradigm is lacking, the use of this

254 vely to study stress distribution in lattice-mismatched semiconductor heterostructures.

255 stringency of its search and sensitivity to mismatched sequences in vivo remain poorly defined.

256 ete discrimination against single nucleotide mismatched sequences under practical conditions and high

257 0 pM, and could discriminate target DNA from mismatched sequences.

258 deduced, with selectivity to single-RNA-base mismatched sequences.

259 rather than across ears, and that tonotopic mismatch should be minimized to maximize the benefit of

260 eaves the DNA backbone specifically near the mismatch site on a 27-mer fragment, consistent with mism

261 monitor the kinetics of base-flipping at the mismatch site.

262 n with attomolar sensitivity and single-base mismatch specificity.

263 Results Immune-mismatched stem cell implants demonstrated stronger feru

264 resonance (MR) imaging of donor-matched and mismatched stem cell transplants demonstrated decreased

265 Then, 48 hours later, immune-matched or mismatched stem cells were implanted into osteochondral

266 ologous tail, Msh2 promotes the rejection of mismatched substrates.

267 ismatch is not completely resolved in highly mismatched systems such as in GaN-on-Si.

268 NA distinguishing perfect-matched and single-mismatched target DNA molecules to the best extent, like

269 h site on a 27-mer fragment, consistent with mismatch targeting.

270 e trapped in an inactive state when bound to mismatched targets.

271 al visual field, which could either match or mismatch the shape category of the memorized stimulus.

272 ion performance, when it matched rather than mismatched the concurrently memorized content, despite i

273 Despite the species mismatch, the mouse Prox1-EGFP BAC enabled a reliable ex

274 In addition to distinguishing nucleotide mismatches, the ITO and magnetic liquid-based approach w

275 54% (95% CI, 32%-68%), despite lineage-level mismatch to B(Yamagata) vaccine.

276 ntrolled by the modulation of the structural mismatch to ice.

277 forests to become increasingly structurally mismatched to water availability and thus overbuilt duri

278 plementary oligonucleotides over single-base-mismatch, two-base-mismatch, and noncomplementary DNA ta

279 showed a high degree of cytosine to thymine mismatches, typical of post-mortem damage.

280 (n = 1), HLA-matched unrelated (n = 9), HLA-mismatched unrelated (n = 3), and HLA haploidentical sib

281 donor is not available, a haploidentical or mismatched unrelated donor (mMUD) can be useful.

282 cell donors were matched unrelated donors or mismatched unrelated donors (n = 18) and matched related

283 With the increasing use of mismatched, unrelated, and granulocyte colony-stimulatin

284 -MaPseq), which encodes DMS modifications as mismatches using a thermostable group II intron reverse

285 with increased kPL This perfusion-metabolism mismatch was also associated with metastasis.

286 Each 1% increase in genome-wide recipient mismatching was associated with an estimated 20% increas

287 from purine-purine and pyrimidine-pyrimidine mismatches were rare (10(-7)-10(-10)).

288 U-->G errors mostly due to pyrimidine-purine mismatches were relatively frequent (10(-5)-10(-6)), whe

289 ing a single site of DNA damage (here a base mismatch) which inhibits DNA charge transport.

290 mechanisms may be insufficient to dampen the mismatches, which we call shocks, and they may remain an

291 eal unanticipated opposing effects of a seed mismatch with implications for mechanism and guide-RNA d

292 instability due to mechanical and structural mismatch with the brain.

293 ly of rhodium metalloinsertors that bind DNA mismatches with high specificity and are preferentially

294 t rates, potentially leading to phenological mismatches with negative fitness consequences.

295 The association of HLA mismatching with kidney allograft survival has been well

296 ally focus proximately or evoke evolutionary mismatches, with minimal clinical value.

297 This ability is due to a G-G mismatch within the fish miR-451 precursor, which substa

298 ands of DNA are not identical, there will be mismatches within the heteroduplex DNA (hetDNA).

299 pite the presence of up to 2 target-sequence mismatches within the primer or probe binding region.

300 les positive identification of pedigree from mismatched Y-STR haplotypes.