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1 No improvement occurred when frequencies mismatched.
2 CB) units and patients are often HLA class I mismatched.
3 3% [n = 142]; 8/10, 38.2% [n = 60]; MICA-129 mismatched 10/10, 3.9% [n = 54]; 9/10, 10.2% [n = 65]; 8
4 ased with the number of HLA mismatches (MICA mismatched 10/10, 9.2% [n = 127]; 9/10, 22.3% [n = 142];
5 ved in the 10/10 match group if MICA-129 was mismatched (10/10, hazard ratio [HR], 1.77; confidence i
6 (80.7 vs 74.4%, P < 0.001), less likely sex mismatched (21.5 vs 27.5%, P < 0.001), more likely race
8 (21.5 vs 27.5%, P < 0.001), more likely race mismatched (57.4 vs 52.4%, P < 0.001), and had less tota
9 le mismatched, 70% (65-75) after two alleles mismatched, 62% (57-68) after three alleles mismatched,
10 er HLA matched, 76% (71-81) after one allele mismatched, 70% (65-75) after two alleles mismatched, 62
11 recipients spontaneously accepted fully MHC-mismatched A/J renal allografts, recipients containing d
12 is compact structure by an electrostatically mismatched A86K mutation profoundly affected the DNA bin
14 resent a new statistical algorithm, MACHETE (Mismatched Alignment CHimEra Tracking Engine), which ach
17 se interactions induces tolerance in a fully mismatched allogeneic splenocyte transfer model in mice.
18 ing an immunocompetent murine model of minor mismatched allogeneic transplantation followed by donor-
20 m and immunosuppression withdrawal in highly mismatched allograft recipients using a bioengineered st
21 val of full major histocompatibility complex mismatched allografts, whereas all similarly treated wil
22 ed multiple minor histocompatibility antigen-mismatched alloHCT using bone marrow (BM) cells and sple
23 rovided by specificity analysis using single mismatched and complementary oligonucleotide sequences.
24 e or IFN-gamma(-/-) counterparts in both MHC-mismatched and MHC-matched but minor histocompatibility
27 ecipients, including 125 cord blood, 125 HLA-mismatched, and 154 HLA-matched HCTs, detection of multi
29 mismatched, 62% (57-68) after three alleles mismatched, and 49% (41-57) after four or more alleles m
32 to Mycobacterium tuberculosis in MHC class I-mismatched animals, as well as from Th1-biased dams to T
35 e performed major histocompatibility complex mismatched aorta to carotid artery interposition grafts,
36 In both a minor histocompatibility antigen-mismatched as well as a MHC-haploidentical model of scle
37 he allele level for HLA A, B, C, and DRB1 or mismatched at a single HLA locus received bone marrow gr
38 tween transplantations that were matched and mismatched at one allele (HR 1.18, 95% CI 0.80-1.72, p=0
39 , mortality was higher with transplantations mismatched at two (hazard ratio [HR] 1.55, 95% CI 1.08-2
41 r partial calendar-time adjustment for clade-mismatched B/Wisconsin/01/2010-like virus (VE, 63%; 95%
42 using minor major histocompatibility complex-mismatched B6.C-H2 donor hearts in C57BL/6(H-2) recipien
43 howed that CC (PEG MG) islets from fully MHC-mismatched Balb/c mice supported long-term (>100 days) s
46 ntibody was used in a multiple minor antigen-mismatched, BALB.B (H-2B) to C57BL/6 (H-2B), cardiac all
48 ctly complementary target, while the type of mismatched base had negligible influence on the results.
49 resolving dC-rC pairs either by excising the mismatched base or switching templates prematurely, whil
50 cation, we developed a novel system to study mismatched base pair resolution during HIV-1 replication
51 asing relative yield with temperature from a mismatched base pair, and these effects are accounted fo
53 mainly include DNAzymes, G-quadruplexes, and mismatched base pairs and nanomaterials cover gold nanop
54 mperature measurements comparing matched vs. mismatched base pairs at duplex DNA termini are far too
55 only accelerates the removal of uracil from mismatched base pairs but also enables the enzyme to gai
56 differentiating DNA duplexes containing the mismatched base pairs CC and CA at single molecule resol
57 pares the thermal stabilities of matched and mismatched base pairs in DNA duplexes containing or not
63 iniscent of DNA repair enzymes that displace mismatched bases, and is differentiated from other DNA-t
65 xtend the supracrystalline growth to lattice-mismatched binary nanocrystal superlattices, in order to
68 pression by NK cells is required for in vivo-mismatched bone marrow allograft rejection as well as fo
70 er when the recipient and donor are HLA-DPB1-mismatched, but the mechanisms leading to GVHD are unkno
71 ed major histocompatibility complex class II mismatched C57BL/6N (H-2; B6) or B6.RIP3 (H-2; RIP3) mic
73 Tregs led to long-term survival of fully MHC-mismatched cardiac allografts, and prevented development
77 tive detection of target miRNA employing the mismatched catalytic hairpin assembly (CHA) amplificatio
78 multi component nucleic acid enzyme-mediated mismatched catalyzed hairpin assembly (MNAzyme-CHA).
79 sms for this, we compared the ability of HLA-mismatched CB and adult peripheral blood (PB) T cells to
80 In contrast, we observe that binocularly mismatched cells are more mismatched in orientation tuni
82 uses, the utility of vaccines in the face of mismatched circulating strains remains questionable.
84 vity of neurons only from the same region in mismatched cocultures, exhibiting region-matched astrocy
86 und that co-reconstitution with 2 KIR ligand-mismatched compartments did not alter the frequency of K
87 ts complexes with perfect-matched and single-mismatched complementary DNA molecules were examined by
89 th of epitaxial nanocomposites using lattice-mismatched constituents also enables strain-engineering,
90 Simulations using 46 ICPs and 11 fully HLA-mismatched CPs were undertaken using the Australian KPD
91 of an RPBA cutoff with RPBA data) and assay-mismatched cutoffs (e.g., with the use of microbiologic
93 ciency for assay-matched compared with assay-mismatched cutoffs were 35% compared with 56% (serum fol
94 ciency for assay-matched compared with assay-mismatched cutoffs were 5.6% compared with 16% (serum fo
95 s that use ecologically- and physiologically-mismatched diets over-estimate susceptibility and under-
96 e capabilty to discriminate single-base-pair mismatched DNA mutation (single nucleotide polymorphism)
98 tes on single-stranded, double-stranded, and mismatched DNA were comparable between Pol and Pol2core.
99 act as a platform to recruit EcMutL onto the mismatched DNA, forming an EcMutS-EcMutL search complex
100 after the first MVA-CMDR boost, the sequence-mismatched DNA-prime MVA-boost vaccine strategy induced
101 s of acute leukemia, a transplant from a HLA-mismatched donor and from cord blood, older age, and dur
102 ctive transgenic T cells is dependent on MHC-mismatched donor BM-derived APCs but not on donor BM-der
103 n associated with de novo antibodies against mismatched donor HLA antigens in kidney transplantation.
113 tioselectivities, where a pronounced matched/mismatched effect with the chirality of the allyltrifluo
116 lly, these gamma rhythms were linked back to mismatched expectations or "luck" occurring in past tria
119 vides a new method for sound regulation at a mismatched fluidic interface and has extensive frequency
120 e of the composite waveguide at an impedance-mismatched fluidic interface, tunable sound transmission
122 bserved in a patient, HLA 10/10 matched, but mismatched for HLA-DRB3 and HLA-DPB1 compared with the d
123 thin each HLA match group, cases matched and mismatched for MICA and MICA-129 were analyzed for the e
125 conclude that immune responses to "sequence-mismatched" FVIII products are unlikely to contribute ap
126 (MVA)-boost vaccination strategy, which uses mismatched Gag immunogens in the TamoVac 01 phase IIa tr
127 cence (operational tolerance) against an HLA-mismatched graft, allowing them to withdraw all immunosu
129 anting MHC-matched, minor histocompatibility-mismatched grafts composed of purified HSCs, HSCs plus b
130 ase, the risk of death was higher in the HLA-mismatched group than in the cord-blood group (hazard ra
131 ociations was lower (hazard ratio in the HLA-mismatched group, 1.28; 95% CI, 0.51 to 3.25; P=0.60; ha
132 d ratios were lower (hazard ratio in the HLA-mismatched group, 1.36; 95% CI, 0.76 to 2.46; P=0.30; ha
133 he cord-blood group (hazard ratio in the HLA-mismatched group, 3.01; 95% CI, 1.22 to 7.38; P=0.02; ha
134 ve TCRs with endogenous TCRalpha-chains; MHC-mismatched H-2(b) but not matched H-2(g7) mixed chimeris
135 /-).BDC2.5 mice into lethally irradiated MHC-mismatched H-2(b) C57BL/6 or MHC-matched congenic B6.H-2
137 at a swine virus with extremely functionally mismatched HA and NAs (pH1N1low-1) cannot transmit via a
138 emic potential increases yearly when a group-mismatched HA subtype dominates seasonal influenza circu
140 biology of human leukocyte antigen haplotype mismatched ("haploidentical") transplantation, its trans
141 multiple viruses included cord blood or HLA-mismatched HCT, myeloablative conditioning, and acute gr
142 transplantation of a minor antigen (HY) sex-mismatched heart graft, the lymphatic flow index was sig
145 group 3 (n = 2) underwent haploidentical MHC-mismatched heart/kidney transplantation; and group 4 (n
146 ansgenic mice and in patients undergoing HLA-mismatched hematopoietic cell transplantation (HCT), NK
149 s recognized primary leukemic cells when the mismatched HLA class II allele was shared between NE-CBU
151 ive effector CD4(+) T cells toward 1 or more mismatched HLA class II alleles of the NE-CBU were detec
154 ompared with the risk among recipients whose mismatched HLA-DPB1 allele was linked to rs9277534A (low
155 he risk of acute GVHD among recipients whose mismatched HLA-DPB1 allele was linked to rs9277534G (hig
156 ted the difference in FD scores (DeltaFD) of mismatched HLA-DPB1 alleles in patients and their 10/10
160 clonal CD4 T cell response against patient's mismatched HLA-DRB3 molecule was found in addition to an
163 HIV-1 that persist upon transmission to HLA-mismatched hosts may spread in the population as the epi
164 he decreased melting temperature of the tL.C mismatched hybrid as compared to that of the t.C mismatc
165 atched hybrid as compared to that of the t.C mismatched hybrid, while the melting temperatures of the
172 ransplant, group 1 (n = 3) underwent class I-mismatched kidney transplantation; group 2 (n = 3) under
173 oup 2 (n = 3) underwent 2 sequential class I-mismatched kidney transplantations; group 3 (n = 2) unde
174 ing a fully major histocompatibility complex-mismatched, life-sustaining, murine model of renal allog
175 en achieved in recipients of HLA-matched and mismatched living donor kidney transplants in 3 medical
176 owever, when two Y-STR haplotypes have a few mismatched loci, it is difficult to determine if they ar
178 ed with 33.4% (95% CI, 29.3 to 37.2) against mismatched malaria (1951 infections) (P=0.04 for differe
183 tudy, we directly tested the hypothesis that mismatched MHC class II in mixed chimeras mediates delet
187 aken together, our studies indicate that MHC-mismatched mixed chimerism can mediate thymic deletion o
190 ies used high doses of CD4(+) T cells in MHC-mismatched models that caused rapid and lethal GVHD.
194 ngent major histocompatibility complex fully mismatched mouse models were used to evaluate the alloim
195 Using the major histocompatibility complex-mismatched mouse orthotopic lung transplant model, we in
197 full major histocompatibility complex (MHC)-mismatched, multiorgan system model with BO, donor T-cel
198 ng MHC II-mismatched, parent-->F1, and miHAg-mismatched murine bone marrow transplantation models.
200 ted significantly improved discrimination of mismatched (mutant) alleles from matched (wild-type) all
205 utative off-target sites, which have 3 and 1 mismatched nucleotides with GhMYB25-like-sgRNA1 and GhMY
206 templating, where small precursor units with mismatched numbers of complementary functional groups ar
207 ng the proportions of reacting peptides with mismatched numbers of complementary reactive groups resu
210 nger than the geranylated T-A pair and other mismatched pairs in the B-form DNA duplex context, which
212 t not female (HY(-)) recipients using MHC II-mismatched, parent-->F1, and miHAg-mismatched murine bon
213 nor-derived target cells transduced with the mismatched patient variant HLA-DRB3 and HLA-DPB1 molecul
214 that depend on resources showing temporally mismatched patterns should be expected to schedule routi
215 ived saline (negative control), unsorted MHC-mismatched PBMC (positive control), PBMC enriched with C
216 co-cultures between human leukocyte antigen-mismatched peripheral blood lymphocytes from healthy adu
217 which adopts a novel differential and angle-mismatched polarizing optical design achieving wide-fiel
218 ion with isothermal DNA amplification, using mismatched primers in conjunction with a two-round enric
220 -up in a phase IIb tolerance protocol in HLA-mismatched recipients of living donor kidney plus facili
221 graft dendritic cells was sought in nine sex-mismatched recipients using XY fluorescence in situ hybr
222 rain (44/76-SL, which included fHbp) and one mismatched reference strain (5/99, which included neisse
223 ive binding in the heteroduplex allows short mismatched regions to be incorporated in otherwise homol
225 re were no differences in survival after HLA-mismatched related, HLA-matched unrelated, or mismatched
226 with myeloid malignancy and those receiving mismatched related/haploidentical grafts, were 80% (+/-6
227 afts from HLA-matched siblings, 13% from HLA-mismatched relatives, 12% from HLA-matched, and 41% from
228 unique peripheral blood samples from 348 HLA-mismatched renal transplant recipients and 101 nontransp
238 dized wild-type gene together with all other mismatched sequences off the magnetic beads, leaving onl
239 ete discrimination against single nucleotide mismatched sequences under practical conditions and high
240 d to allow the detection of single base pair mismatched sequences, able to detect as low as 10 pM tar
246 mice also delayed rejection of major antigen-mismatched skin and MHC class II-mismatched cardiac allo
248 Here, we used a mouse model of MHC-class I mismatched skin transplantation to investigate the contr
251 resonance (MR) imaging of donor-matched and mismatched stem cell transplants demonstrated decreased
261 ).BDC2.5 TCD BM cells with BM cells from MHC-mismatched T cell-deficient C57BL/6 mice into lethally i
262 potent antileukemic activity following haplo-mismatched, T cell-depleted stem cell transplantations f
263 NA distinguishing perfect-matched and single-mismatched target DNA molecules to the best extent, like
267 CRISPR discriminates between genuine versus mismatched targets for genome editing via radical altera
268 case, we challenged a mixture of matched and mismatched targets, evaluating cleavage activity on a wi
270 eceptors (TCRs) isolated from allogeneic HLA-mismatched TCR repertoires has, however, been impeded by
271 MgdNTP-prebinding ability could stabilize a mismatched ternary complex and destabilize a matched ter
272 ion performance, when it matched rather than mismatched the concurrently memorized content, despite i
273 eparate donors and carry the disadvantage of mismatched tissues and lack the advantage of personalize
275 forests to become increasingly structurally mismatched to water availability and thus overbuilt duri
281 HCT using matched unrelated (n = 25, 55.5%), mismatched unrelated (n = 14, 31.1%), or mismatched rela
282 (n = 1), HLA-matched unrelated (n = 9), HLA-mismatched unrelated (n = 3), and HLA haploidentical sib
285 ad full donor chimerism, all 3 recipients of mismatched unrelated donor HSCT had high levels of donor
288 cell donors were matched unrelated donors or mismatched unrelated donors (n = 18) and matched related
289 nors were matched unrelated donors (n = 72), mismatched unrelated donors (n = 37), matched sibling do
291 D-related outcomes were higher in HLA-DP GVH-mismatched unrelated recipients than in HLA-matched sibl
293 ringes originated from the same rotationally mismatched vdW stacking of BNNSs and can be inter-conver
294 nsplants where donors and recipients are HLA mismatched, we distinguish between donor liver-derived a
295 rs to fully major histocompatibility complex-mismatched Wistar Furth rat or C57 mouse recipients with
296 phic levels may result in predators becoming mismatched with prey availability, reducing fitness and
297 oat colour molt phenology, such that animals mismatched with the colour of their background experienc
298 form of the query - a text-based string - is mismatched with the form of the target - a genomic profi
300 properties of the FePt films grown on large mismatched ZrN (15.7%) intermediate layer were investiga
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