ライフサイエンスコーパス: misuse

1 ption drug misuse, and over-the-counter drug misuse).

2 and oral cancer that can result from alcohol misuse.

3 order, criminality, accidents, and substance misuse.

4 consistently associated with greater alcohol misuse.

5 us diseases, mental disorders, and substance misuse.

6 itiation of substance use and progression to misuse.

7 are effective in the reduction of substance misuse.

8 ng substantial risk of misinterpretation and misuse.

9 l counseling interventions to reduce alcohol misuse.

10 erventions in primary care to reduce alcohol misuse.

11 tors which might predispose youth to alcohol misuse.

12 and concerns about diversion, addiction, and misuse.

13 y seeking evaluation or treatment of alcohol misuse.

14 ing and counseling interventions for alcohol misuse.

15 curve, contribute to propensity for alcohol misuse.

16 s may be associated with prescription opioid misuse.

17 on reducing overuse, and very few focused on misuse.

18 s, and 13.0% (12.2-13.8; n=1323) for alcohol misuse.

19 use; and mild, moderate, and severe alcohol misuse.

20 ted parameters in association with substance misuse.

21 tcomings will optimize performance and avoid misuse.

22 otherapy among individuals with no substance misuse.

23 patients with and without comorbid substance misuse.

24 acy of past decades of antimicrobial use and misuse.

25 portionate to known instances of information misuse.

26 r relatives for their most recent episode of misuse.

27 d the first GEWIS examining risk for alcohol misuse.

28 leave unused opioids available for potential misuse.

29 ures, which would help preventing antibiotic misuse.

30 heir importance across dimensions of alcohol misuse.

31 s that target opioid storage, packaging, and misuse.

32 as the most commonly reported motivation for misuse.

33 icularly if they are comorbid with substance misuse.

34 ve approach to help screen for possible drug misuse.

35 e of this subthalamic network across alcohol misuse.

36 chronic pain promotes higher rates of opioid misuse.

37 erventions) may improve treatment of alcohol misuse.

38 t score positively on the M-SASQ for alcohol misuse.

39 for rapid adaptation if these cultivars are misused.

40 ge in the life sciences be protected against misuse?

41 88-4.56]; p<0.001) and no history of alcohol misuse (0.47 [0.24-0.92]; p=0.027).

42 ession or anxiety (0.91, 0.71-1.16), alcohol misuse (0.88, 0.73-1.06), or seeking support for mental

43 ogical distress 1.34, 0.98-1.85), or alcohol misuse (1.32, 0.97-1.80).

44 atient with mental illness, alcohol and drug misuse (19 victims [66%], 27 perpetrators [93%]) and pre

45 misuse vs 155 [2.3%] of 6768 with no alcohol misuse; 2.16, 1.62-2.90; p<0.0001), post-traumatic stres

46 g depression (13.0, 10.3-16.6) and substance misuse (22.4, 18.3-27.3), compared with patients with no

47 Among adults with misuse, 59.9% reported using opioids without a prescript

48 pioid misuse was defined as drug abuse, drug misuse, aberrant drug-related behavior, diversion, or ad

49 adverse effects of opioids and the risks of misuse, abuse, and overdose in the nonpatient population

50 medication compliance, drug substitution, or misuse/abuse and require follow-up confirmatory testing

51 Previous work has shown patients commonly misuse adrenaline autoinjectors (AAI).

52 Alcohol misuse affects the physical and mental health of people

53 High rates of alcohol misuse after deployment have been reported among personn

54 ast conflicts, yet investigations of alcohol misuse after return from the current wars in Iraq and Af

55 rventions most effective at reducing alcohol misuse after traumatic injury is not known.

56 dies, the proportion of patients with opioid misuse after treatment agreements, urine drug testing, o

57 in those without, particularly in people who misuse alcohol and hard drugs.

58 reening and referral of patients found to be misusing alcohol while attending an emergency department

59 We also included five legal drugs of misuse (alcohol, khat, solvents, alkyl nitrites, and tob

60 d overall, important problems of overuse and misuse also exist.

61 ndary care to detect alcohol consumption and misuse among people diagnosed with psoriasis.

62 isuse, and use disorders and motivations for misuse among U.S. adults.

63 interventions to reduce violence and alcohol misuse among urban adolescents at risk of future injury.

64 Drug misuse and abuse are major health problems.

65 pioids and hence risk of prescription opioid misuse and abuse remains a healthcare concern and a chal

66 them properly, which could lead to potential misuse and abuse.

67 The high comorbidity with alcohol misuse and aggression highlights the need for comprehens

68 Alcohol misuse and aggressive behaviour might be appropriate tar

69 Studies aimed at reducing overuse and misuse and at enhancing the quality and frequency of dis

70 rmed diagnosis is a key driver of antibiotic misuse and could inform antimicrobial stewardship interv

71 tment, and prevention of prescription opioid misuse and dependence.

72 he further benefit of obviating the risk for misuse and diversion of daily buprenorphine while retain

73 collects and analyzes postmarketing data on misuse and diversion of prescription opioid analgesics a

74 also highlight concerns associated with the misuse and diversion of prescription stimulants in ADHD

75 o be vigilant to the potential for stimulant misuse and diversion.

76 ation in susceptibility to opioid medication misuse and eventual addiction in the context of chronic

77 dwide effort is confusion resulting from the misuse and interchangeable application of terms disregar

78 susceptibility testing (AST) would decrease misuse and overuse of antibiotics.

79 antidoping fight is the elimination of drug misuse and prevention of severe adverse effects caused b

80 , there is evidence of widespread continuing misuse and promulgation of poor-quality and insufficient

81 en adults aged 18 years or older for alcohol misuse and provide persons engaged in risky or hazardous

82 ine the feasibility of screening for alcohol misuse and providing brief intervention in a primary den

83 lated disorders, eating disorders, substance misuse and self-harm behaviour.

84 Substance misuse and substance use disorders are important pediatr

85 odels shed light on the aetiology of alcohol misuse and suggest targets for prevention.

86 Misuse and use disorders were most commonly reported in

87 in 2015, with substantial numbers reporting misuse and use disorders.

88 g is simultaneously underused, overused, and misused and that adequate patient-provider discussions a

89 Many young people are misusing and becoming dependent on multiple substances (

90 99 (24.2%) received ESAs for 1 week or less (misuse), and 1,601 (7.6%) received ESAs for more than 14

91 ch suggests that conduct disorder, substance misuse, and ADHD involve both unique forms of dysfunctio

92 NPWs on prescription opioid use initiation, misuse, and dependence.

93 jor depression, generalised anxiety, alcohol misuse, and functional impairment.

94 unger age, female sex, unemployment, alcohol misuse, and greater opioid use in the ICU were significa

95 Coordinated mental health, substance misuse, and hepatitis treatment services increased HCV t

96 , frequent binge drinking, prescription drug misuse, and over-the-counter drug misuse).

97 h antisocial personality disorder, substance misuse, and suicide attempts were explained by factors o

98 s definition of quality as reducing overuse, misuse, and underuse.

99 e the prevalence of prescription opioid use, misuse, and use disorders and motivations for misuse amo

100 n the prevalence of prescription opioid use, misuse, and use disorders are limited.

101 Prescription opioid use, misuse, and use disorders.

102 tors shared between each disorder, substance misuse, and violence.

103 entions for psychiatric disorders, substance misuse, and violence.

104 (schizophrenia, bipolar disorder, substance misuse, and violent crime) were highly heritable (h(2)=5

105 Much of this misuse appears to be owing to the widespread, mistaken b

106 Gallstones and alcohol misuse are long-established risk factors, but several ne

107 Due to the potential misuse as a biothreat agent, abrin is in the focus of su

108 tics and vaccines as well as their potential misuse as bioterrorism agents.

109 ause of their extreme toxicity and potential misuse as biowarfare agents.

110 practice, the ASA-PS classification is often misused as a measure of operative risk, which is the bas

111 Alcohol misuse, as measured by a brief screening questionnaire,

112 hich may be associated with risk for alcohol misuse, as well as those which may occur as a result of

113 or generalised anxiety disorder, and alcohol misuse at follow-up.

114 n for illicit drug use and prescription drug misuse, based in part on evidence of efficacy for unheal

115 evelopmental interval when continued alcohol misuse becomes more deviant.

116 referral for brief intervention for alcohol misuse benefit patients and reduce demand for accident a

117 rine drug testing to reduce opioid analgesia misuse, but evidence of their effectiveness has not been

118 ts and urine drug testing in reducing opioid misuse by patients with chronic pain.

119 utic approaches to prevent and treat alcohol misuse by understanding the molecular mechanisms of alco

120 the same mechanism is used by symbionts and misused by parasites to evade innate immune responses of

121 ow some specific toxicological data has been misused by those aiming to disingenuously influence publ

122 ssing past-year frequency use for 8 commonly misused categories of substances appears to be a valid m

123 Substance misuse contributed most to the increased risk of BBV: af

124 treat pain, but are becoming the most widely misused controlled substance nationally.

125 y intervention programs for drug and alcohol misuse could substantially decrease the greatly elevated

126 In people with a prior history of opioid misuse, cues associated with previous drug intake can tr

127 Despite the continuing epidemic of opioid misuse, data on the prevalence of prescription opioid us

128 reatment for alcohol, cannabis, or hard drug misuse), date of death, primary cause of death, and educ

129 cipants; 1.84, 1.41-2.39, p<0.0001), alcohol misuse disorder (eight studies, 5040 participants; 1.44,

130 pants; 1.90, 1.39-2.61, p<0.0001), substance misuse disorders (11 studies, 5469 participants; 1.84, 1

131 reatment exist-comes from studies of alcohol misuse disorders or non-alcohol-related Wernicke-Korsako

132 ere 8 times more likely to develop substance misuse disorders).

133 disease especially in the absence of alcohol misuse disorders.

134 smucosal formulations can be associated with misuse, diversion, and nonadherence; these limitations m

135 to 15% of all healthcare professionals will misuse drugs or alcohol at some time during their career

136 those which may occur as a result of alcohol misuse during adolescence and emerging adulthood.

137 g effects on mental health, drug and alcohol misuse (especially in girls), risky sexual behaviour, ob

138 imary cause of this resistance is antibiotic misuse, especially routine inappropriate use of antibiot

139 h low socioeconomic status, drug and alcohol misuse, ethnic origin, and sex.

140 influences that were unrelated to substance misuse explained approximately a fifth (21%; 20-22%) of

141 ounger and had a higher incidence of alcohol misuse, fewer comorbidities, lower severity of illness,

142 imported infections and through the fear of misuse for biological terrorism.

143 n the effectiveness of screening for alcohol misuse for improving health outcomes, the accuracy of va

144 an was significantly associated with alcohol misuse for regulars (odds ratio 1.22, 95% CI 1.02-1.46)

145 improvement efforts suggest that antibiotic misuse for surgical disease is common.

146 cioeconomic status, education, and substance misuse) for BBV infection.

147 patients was lower in the 3 highest alcohol misuse groups (adjusted percentage of adherent patients,

148 patients was lower in the 2 highest alcohol misuse groups (adjusted percentage of adherent patients,

149 onditions, depressed patients with substance misuse had an increased probability of ongoing depressio

150 e volume reduction, and alcohol/illicit drug misuse had no significant associations when effects of t

151 ature suggest that toxicities may result and misuse has been underestimated, yet little information i

152 The current epidemic of prescription opioid misuse has increased scrutiny of postoperative opioid pr

153 for basic needs, combat experience, alcohol misuse, history of violence and arrests, and anger assoc

154 atient treatment for alcohol intoxication or misuse (HR = 1.98, 95% CI 1.76-2.21, p < 0.001).

155 r reduce conditions complicated by substance misuse, if services are accessible.

156 er premorbid or the consequence of substance misuse, imply a source of the susceptibility to relapse

157 s in primary care settings to reduce alcohol misuse in adolescents.

158 stic identification and referral for alcohol misuse in an emergency department is feasible, associate

159 sh a predictive tool for identifying hormone misuse in cattle.

160 ion to the loss of tax revenue, with alcohol misuse in England and Wales costing pound21 billion a ye

161 rts have to be put into explaining substance misuse in general, identifying which characteristics of

162 revent the onset and escalation of substance misuse in high-risk adolescents.

163 dge about the neuropharmacology of substance misuse in man.

164 ay be linked to more problems with substance misuse in parents and greater pathology in the child.

165 rticle discusses the scope of the antibiotic misuse in surgery for surgical patients, and provides im

166 edicted from the tragedy associated with its misuse in the past, its history serves as a lesson in dr

167 have been found to reduce substance use and misuse in those with elevated personality profiles.

168 Exposure to maternal drug misuse in utero is associated with a statistically signi

169 contribute to the increased rates of alcohol misuse in young people at-risk for BD, and suggest possi

170 nd hypothesis testing methods are frequently misused in clinical research.

171 achieved: generic drugs may be underused or misused in comparison to prescription drugs because of a

172 eceived only limited attention and have been misused in many instances.

173 secretory pathway (GSP) has been usurped and misused in the literature over the past few years.

174 te to their (intended) benefit in preventing misuse, in these 11 European countries.

175 ay statistical tools are used, if not indeed misused, in biodiversity research.

176 ve impairment is a recognized effect of drug misuse, including the use of opiates.

177 ression, hostility, and history of substance misuse increase risk for future suicidal behavior, while

178 Monitoring for benefit and opioid misuse is accomplished by having frequent face-to-face a

179 Co-occurring substance misuse is associated with depression and with increased

180 Opioid misuse is at historically high levels in the United Stat

181 Antibiotic use and misuse is driving drug resistance.

182 banization being a risk factor for substance misuse is examined.

183 Alcohol misuse is highly prevalent among people attending emerge

184 Severe but not mild to moderate alcohol misuse is independently associated with an increased ris

185 effective ways to monitor and reduce opioid misuse is needed, especially in primary care settings.

186 s unclear, but research suggests that opioid misuse is not rare.

187 Alcohol misuse is the leading cause of cirrhosis and the second

188 lthough it has been suggested that substance misuse is typically a characteristic of large urban area

189 cations in human medicine, and potential for misuse, it is of considerable importance to elucidate th

190 g men include psychiatric illness, substance misuse, lower socioeconomic status, rural residence, and

191 rnal and infant starvation, and by substance misuse (marijuana, khat) in late childhood and adolescen

192 Alcohol misuse may be a risk factor for nonadherence; however, e

193 Propensity for alcohol misuse may be linked to an individuals' response to alco

194 diseases (men: 0.9; women: 1.4) and alcohol misuse (men: 2.8; women: 1.2).

195 , including alcohol, tobacco, and other drug misuse, mental health problems, unsafe sex, risky and un

196 mprehensive account of the causes of alcohol misuse must accommodate individual differences in biolog

197 y in treating certain gross symptoms of drug misuse, namely, motor activation, self-administration, a

198 As commonly misused, null-hypothesis significance testing combines t

199 Accidental or intentional misuse of acetaminophen (APAP) is the leading cause of a

200 From 2004 to 2013, underuse and misuse of AET have decreased for patients with breast ca

201 scuss the functional consequences of use and misuse of alternative promoters in normal and disease ge

202 us concerns about the widespread overuse and misuse of antibiotics contributing to increased antibiot

203 The misuse of antibiotics during past decades has led to per

204 The extensive use and misuse of antibiotics during the last seven decades has

205 Bacterial resistance due to the misuse of antibiotics has become a global issue and alte

206 The overuse and misuse of antibiotics has been identified as a significa

207 athogenic bacteria, made worse by widespread misuse of antibiotics.

208 tant implications for the widespread use and misuse of antibiotics.

209 has been attributed to long-term, widespread misuse of antimonial drugs within the Indian private hea

210 rd mathematical framework to illustrate that misuse of association patterns, as guidance for implemen

211 y important perspective on the potential for misuse of both guidelines and performance measures.

212 threat and is often linked with overuse and misuse of clinical and veterinary chemotherapeutic agent

213 dual effects, limiting misinterpretation and misuse of data.

214 Proper assessment of the harms caused by the misuse of drugs can inform policy makers in health, poli

215 anium is necessary to minimize the potential misuse of highly enriched uranium in the world for nonpe

216 reducing violence in drug markets, lessening misuse of legal pharmaceuticals, preventing drug use ini

217 s, denial of access to medical services, and misuse of medical facilities and emblems have become a f

218 The use and misuse of medical technology also pose risks, such as dr

219 on with behavioral disinhibition and the use/misuse of nicotine, alcohol, and illicit drugs.

220 matically increased, including incidences of misuse of opioid drugs prescribed for pain control.

221 Control measures designed to prevent the misuse of opioid medicines can often unintentionally res

222 Misuse of opioids is associated with abnormalities of pi

223 The use and misuse of P values has generated extensive debates.

224 IPAA was implemented to reduce potential for misuse of personal information and restricts access to m

225 Misuse of potent new agents will, however, result in the

226 demonstrate critical issues arising from the misuse of principal component regression that result in

227 concerns over widespread overmedication and misuse of psychotropic medications in US youth.

228 though futile treatment is acknowledged as a misuse of resources by many, no study has evaluated its

229 nsmission of infectious agents caused by the misuse of respiratory precautions.

230 lways utilise consistent terminology and the misuse of some expressions in epidemiology is rife.

231 tractive non-invasive alternative to control misuse of such antibiotic and to ensure food safety by p

232 ed with AR determination to avoid overuse or misuse of the antibiotic.

233 ental release is significant, and deliberate misuse of the data to create a biological weapon is poss

234 Anecdotal reports have surfaced concerning misuse of the HIV antiretroviral medication efavirenz ((

235 several disorders, as well as the potential misuse of the neurotoxin as an agent in biowarfare, has

236 trend of new technology leading to potential misuse of this technology and further leading to stricte

237 They detail common misinterpretations and misuses of the risk stratification method and conclude t

238 earch is needed to characterize the use (and misuse) of DTS.

239 with prescription opioid use, 12.5% reported misuse; of these, 16.7% reported a prescription opioid u

240 o examine the effects of alcohol and cocaine misuse on periodontal status in a group of alcohol-depen

241 s have shown common effects of substances of misuse on the brain, such as an acute increase in dopami

242 But regression is often misused on such data, ignoring statistical issues relate

243 fects of excess alcohol consumption (alcohol misuse) on outcomes in patients with acute lung injury h

244 whether predisposed individuals will use or misuse one class of psychoactive substances rather than

245 rmacies is a means by which some individuals misuse opioids.

246 Alcohol misuse or aggressive behavior comorbidity was present in

247 f life, functional outcomes, adverse events, misuse or diversion, and risk assessment or mitigation.

248 not assessed functional impairment, alcohol misuse, or aggressive behavior as comorbid factors occur

249 brain injury, brain tumour, drug or alcohol misuse, or dementia were not eligible for inclusion.

250 s disorder (PTSD), major depression, alcohol misuse, or other mental health problems; referral and us

251 identify predictors of adolescent substance misuse, particularly if it can incorporate a wide range

252 ntal disorders, and programmes for substance misuse prevention and treatment.

253 0.91, 95% CI 0.40-2.05; p=0.82) or substance misuse problems (0.55, 0.27-1.17; p=0.12).

254 ly problems, and mental health and substance misuse problems.

255 istress, multiple physical symptoms, alcohol misuse, problems at home during and after deployment, an

256 n the reported prevalence in alcohol use and misuse rates, most published studies document that adole

257 ate substitution treatments reduce substance misuse relapse and possibly reoffending.

258 ptoms of common mental disorders and alcohol misuse remain the most frequently reported mental disord

259 in decreasing prescription opioid abuse and misuse, research focusing on the development and evaluat

260 hizophrenia patients as a result of cannabis misuse (rs9450898).

261 nts, we derived separate dimensional alcohol misuse scales and applied a proxy-phenotype study design

262 on of illicit drug use and prescription drug misuse screening and brief intervention.

263 Alcohol misuse screening and treatment was feasible in a primary

264 uestionnaire, a validated 3-question alcohol misuse screening test.

265 Cocaine is one of the most commonly misused stimulant which could influence the central nerv

266 for intervening with young people who use or misuse substances and recommends their contents.

267 the problems experienced by young people who misuse substances evidence the requirement for specialis

268 s, and future directions for adolescents who misuse substances.

269 vening to meet the needs of young people who misuse substances.

270 ildren born between 2000 and 2004 to mothers misusing substances during pregnancy; (2) assessment at

271 Exclusions included alcohol/drug misuse, suicidal plan or recent attempt, bipolar disorde

272 nding, 3.62; 95% CI, 3.41-3.84) and cannabis misuse (suicide attempt, 3.57; 95% CI, 3.25-3.92; violen

273 gh shares of excess mortality due to alcohol misuse, suicide, and accidents.

274 els of current and future adolescent alcohol misuse that incorporate brain structure and function, in

275 Among clients with no substance misuse, the quality improvement programs improved depres

276 Among clients with comorbid substance misuse, the quality improvement programs were associated

277 nt to know what would happen if a researcher misused their health information; fewer (51%, CI: 47%-55

278 ed prescription opioids; 11.5 million (4.7%) misused them; and 1.9 million (0.8%) had a use disorder.

279 underlying individual differences in alcohol misuse, these models shed light on the aetiology of alco

280 When misused, these studies are expensive and time consuming.

281 iency", is frequently used, and on occasions misused, to compare the reactivity of two enzymes acting

282 l network-focused interventions in substance misuse treatment.

283 iveness of family interventions in substance misuse treatment.

284 ngly associated with post-deployment alcohol misuse (violent offending in 120 [9.0%] of 1363 men with

285 nding in 120 [9.0%] of 1363 men with alcohol misuse vs 155 [2.3%] of 6768 with no alcohol misuse; 2.1

286 In a multivariable analysis, ESA misuse was associated with MD degree, female sex of phys

287 Alcohol misuse was common with 70 (7%) of patients having Alcoho

288 95% CI 3.9%-26.3%), while alcohol/substance misuse was commonly reported by adults (12.9%, 95% CI 9.

289 The outcome of opioid misuse was defined as drug abuse, drug misuse, aberrant

290 rder (PTSD), depression, anxiety, or alcohol misuse was effective.

291 In 4 studies with comparison groups, opioid misuse was modestly reduced (7% to 23%) after treatment

292 Alcohol misuse was the highest risk factor for DALYs (7.0% overa

293 The most commonly reported motivation for misuse was to relieve physical pain (63.4%).

294 Traumatic brain injury and alcohol misuse were related to the outcome variables in bivariat

295 Alcohol misuse, which includes the full spectrum from risky drin

296 th death from digestive-system disease, drug misuse with mental and behavioural disorders, and physic

297 rne viruses (including risks related to drug misuse) with people who have serious mental illness, as

298 Targeting of comorbid substance misuse would have particular effect on reduction of BBV

299 drinking (zone 2), mild to moderate alcohol misuse (zone 3), and severe alcohol misuse (zone 4) are

300 alcohol misuse (zone 3), and severe alcohol misuse (zone 4) are associated with poor outcomes in pat