ライフサイエンスコーパス: mitochondrial DNA

1 omal and uniparental loci (Y-chromosomal and mitochondrial DNA).

2 in phenotype and cannot be differentiated by mitochondrial DNA.

3 roxy-2'-deoxyguanosine was only increased in mitochondrial DNA.

4 g us to type low-frequency variants in human mitochondrial DNA.

5 red also for homeostasis of mitochondria and mitochondrial DNA.

6 to the matrix after fertilization to degrade mitochondrial DNA.

7 olved in recombinational repair of the human mitochondrial DNA.

8 Tumor clonality was assessed by analyses of mitochondrial DNA.

9 y have been restricted to short fragments of mitochondrial DNA.

10 tes but not in oocytes with normal levels of mitochondrial DNA.

11 and OXPHOS genes carried by both nuclear and mitochondrial DNA.

12 ribonucleotide incorporation in nuclear and mitochondrial DNA.

13 tive oxygen species production and increases mitochondrial DNA.

14 atients with visual loss and mutated G11778A mitochondrial DNA.

15 ally nuclear gene is substituted for ATP8 in mitochondrial DNA.

16 tase core subunit 4 (MT-ND4)) are encoded by mitochondrial DNA.

17 f migration, namely nuclear, chloroplast and mitochondrial DNA.

18 to ATP production by selective depletion of mitochondrial DNA.

19 ibroblasts from affected individuals display mitochondrial DNA abnormalities, associated with multipl

20 DNA disorganization in control cells, while mitochondrial DNA aggregation in the genetic cholesterol

21 , R-loops are of low abundance, and there is mitochondrial DNA aggregation.

22 ation promoted excess cytosolic extrusion of mitochondrial DNA along with increased reactive oxygen s

23 multifocal dystonia related to mutations in mitochondrial DNA, among which the most common were the

24 xt-generation sequencing approach for pooled mitochondrial DNA amplicons.

25 Mitochondrial DNA analyses revealed that both the bat fl

26 Unexpectedly, nuclear and mitochondrial DNA analyses suggest that P. antiquus was

27 ondrial tRNA sequences may be observed after mitochondrial DNA analysis.

28 rm extracellular DNA traps (BETs) containing mitochondrial DNA and granule proteins.

29 se R-loops maps to the control region of the mitochondrial DNA and is complementary to 7S DNA.

30 knowledge on how oxidative stress influences mitochondrial DNA and its replication.

31 We have studied mitochondrial DNA and microsatellite markers in nine pop

32 associated with an accumulation of damage to mitochondrial DNA and proteins.

33 rane potential and the subsequent release of mitochondrial DNA and reactive oxygen species, thus prev

34 machinery is required for the expression of mitochondrial DNA and the biogenesis of the oxidative ph

35 ondria, including complementation of damaged mitochondrial DNAs and the maintenance of membrane poten

36 erived from mitochondria: hydrogen peroxide, mitochondrial DNA, and cytochrome c.

37 d one bone that is Neanderthal, based on its mitochondrial DNA, and dated it directly to 46,200 +/- 1

38 s with different lengths of both nuclear and mitochondrial DNA, and each primer was used to amplify t

39 mitochondrial morphology, reduced levels of mitochondrial DNA, and increased levels of mitochondrial

40 this study that IL-26 binds to genomic DNA, mitochondrial DNA, and neutrophil extracellular traps, a

41 aphic structure in maternally inherited host mitochondrial DNA, appeared completely isolated.

42 orsemeat using just 50 ng of total extracted mitochondrial DNA ( approximately 16660 bp in length) wi

43 Proteins encoded by mitochondrial DNA are translated using mitochondrially e

44 is common variation on the Y chromosome and mitochondrial DNA associated with behavioural and psychi

45 Many molecules of mitochondrial DNA bear a third strand of DNA, known as "

46 besogenic diet was associated with increased mitochondrial DNA biogenesis (copy numberP< 0.05; transc

47 of DNA from prehistoric Europeans focuses on mitochondrial DNA, bringing fresh surprises and filling

48 conserved sequence block 2 (CSB 2) in human mitochondrial DNA can result in transcription terminatio

49 ta, dated on the assumption of a "universal" mitochondrial DNA clock are not valid.

50 ear DNA and yet carried different sources of mitochondrial DNA, CMs derived from iPSC and nt-ESCs cou

51 Mitochondrial DNA-CN further improved sensitivity and sp

52 Mitochondrial DNA-CN measured from buffy coat/circulatin

53 Mitochondrial DNA-CN was independently associated with i

54 Analyses of mitochondrial DNA confirmed the independent origin of th

55 ial structural component cardiolipin, of the mitochondrial DNA content, and of the mitochondrial DNA

56 ed stress response, exhibited an increase in mitochondrial DNA content, and required oxidative phosph

57 Indeed, reduced mitochondrial DNA copy number (mitochondrial DNA deficie

58 Mitochondrial DNA copy number (mtDNA-CN), which represen

59 dexed by leukocyte telomere length (LTL) and mitochondrial DNA copy number (mtDNAcn), might partly ac

60 idative stress, which can lead to changes in mitochondrial DNA copy number (mtDNAcn).

61 Notably, the mitochondrial DNA copy number and peroxisome proliferato

62 Mitochondrial DNA copy number in eoPE placentas was sign

63 eficiencies associated with a marked loss of mitochondrial DNA copy number in skeletal muscle.

64 No reduction of mitochondrial DNA copy number was observed.

65 diation analysis estimated that decreases in mitochondrial DNA copy number, a measure of mitochondria

66 Although mitochondrial DNA copy numbers were not altered in Mb-ov

67 i mitogenomes, and exhibited 98-100% partial mitochondrial DNA Cytochrome Oxidase I (mtCOI) gene iden

68 exploration of biodiversity, and large-scale mitochondrial DNA cytochrome oxidase I barcoding has exp

69 We detected the mitochondrial DNA cytochrome oxidase subunit I (COI) bar

70 ction (PCR) assay using conserved regions of mitochondrial DNA (cytochrome b gene) was performed to e

71 pecific for a characteristic fragment of the mitochondrial DNA D-loop region of horse onto the surfac

72 rosis by augmenting alveolar epithelial cell mitochondrial DNA damage and apoptosis.

73 Redox cycling, mitochondrial DNA damage and electron transport chain in

74 by incorporating a novel representation for mitochondrial DNA damage and repair.

75 sies from patients with DKD showed increased mitochondrial DNA damage associated with glomerular endo

76 Direct mitochondrial DNA damage is the principal pathway of chr

77 c respiration, increased oxidant stress, and mitochondrial DNA damage that, in turn, was linked to al

78 The consequences of persistent genomic and mitochondrial DNA damage, including inflammation, cell s

79 in activity, increased oxidative stress, and mitochondrial DNA damage.

80 toxic nucleoside accumulation, and secondary mitochondrial DNA damage.

81 deficiency resulting in the accumulation of mitochondrial DNA damage.

82 ent genome-wide autosomal, Y chromosome, and mitochondrial DNA data from Iranian and Indian Zoroastri

83 deed, reduced mitochondrial DNA copy number (mitochondrial DNA deficiency) may disrupt oocyte quality

84 ty, we supplemented pig oocytes selected for mitochondrial DNA deficiency, reduced cytoplasmic matura

85 To overcome mitochondrial DNA deficiency, whilst maintaining genetic

86 tion prior to embryonic genome activation in mitochondrial DNA deficient oocytes but not in oocytes w

87 ers that were identified in blastocysts from mitochondrial DNA deficient oocytes.

88 outcome and subsequent embryo development to mitochondrial DNA deficient oocytes.

89 nal ophthalmoplegia associated with multiple mitochondrial DNA deletions, whereas recessive SLC25A4 m

90 by confirmatory experiments, we report that mitochondrial DNA depletion leads to an ATF4-mediated in

91 e mutations were shown to be associated with mitochondrial DNA depletion syndrome, the function of MP

92 to retrograde signaling initiated by partial mitochondrial DNA depletion, although distinct differenc

93 rturbations of cholesterol homeostasis cause mitochondrial DNA disorganization in control cells, whil

94 osomal degradation to avoid the detection of mitochondrial DNA during infection.

95 The CcO core is formed by mitochondrial DNA-encoded Cox1, Cox2, and Cox3 subunits.

96 Three mitochondrial DNA-encoded proteins, Cox1, Cox2, and Cox3

97 of mitochondrial transcription factor A and mitochondrial DNA-encoded respiratory complexes constitu

98 f OXPHOS subunits, and in gene expression of mitochondrial DNA-encoded subunits.

99 ss of respiratory chain complexes containing mitochondrial DNA-encoded subunits.

100 to detect heteroplasmy from the concomitant mitochondrial DNA fraction sequenced in these experiment

101 phoblastoid cell lines: targeted cleavage of mitochondrial DNA fragments using CRISPR technology and

102 Here, we use radiocarbon dates and ancient mitochondrial DNA from late Pleistocene bison fossils to

103 A new study of ancient mitochondrial DNA from Newfoundland and Labrador indicat

104 o-date tool to reconstruct and analyze human mitochondrial DNA from NGS data and (iii) the implementa

105 deficient in essential factors required for mitochondrial DNA gene expression, leading to OXPHOS dys

106 Human mitochondrial DNA haplogroup U is among the initial mate

107 udy participants, we determined the roles of mitochondrial DNA haplogroup variation and mitochondrial

108 included 4,211 males and 4,009 females with mitochondrial DNA haplogroups and 4,788 males with Y chr

109 ed and real datasets (Rugao longevity cohort mitochondrial DNA haplogroups and kidney cancer RNA-seq

110 males and females; however Y chromosome and mitochondrial DNA haplogroups were not associated with a

111 ted the association between Y chromosome and mitochondrial DNA haplogroups with sexually-dimorphic be

112 ound in Arizona contains two closely related mitochondrial DNA haplotypes--one present in only female

113 nine in media could lead to higher levels of mitochondrial DNA in [PSI (+)] in ade1-14 cells.

114 and hypoxia, which correlates with decreased mitochondrial DNA in a HIF1/2alpha-independent manner.

115 f NETs but also of pro-inflammatory oxidized mitochondrial DNA in autoimmune diseases.

116 Analysis of replicating mitochondrial DNA in embryonic fibroblasts lacking RNase

117 e I interferon response, recognizes viral or mitochondrial DNA in the cytoplasm via activation of the

118 th the accumulation of multiple deletions of mitochondrial DNA in the later-onset myopathic cases, we

119 dness) and genetic differentiation (based on mitochondrial DNA) in order to compare insular butterfly

120 integrates mitochondrial protein import with mitochondrial DNA inheritance.

121 icated in the assembly of OM proteins and in mitochondrial DNA inheritance.

122 ondrial energy production, oxidative stress, mitochondrial DNA instability, abnormalities in the regu

123 hondrial respiratory capacity and release of mitochondrial DNA into the cytosol.

124 d by a low frequency of hybridization, where mitochondrial DNA introgression is relatively common, wh

125 s demonstrate the importance of the oocyte's mitochondrial DNA investment in fertilization outcome an

126 Cisplatin-seq reveals that mitochondrial DNA is a preferred target of cisplatin.

127 The colonization of the nuclear genome by mitochondrial DNA is an ongoing process in eukaryotes an

128 ked out Parkin in a mouse model in which the mitochondrial DNA is damaged in dopaminergic neurons.

129 The genetic information in mammalian mitochondrial DNA is densely packed; there are no intron

130 DNA damage affecting both genomic and mitochondrial DNA is present in a variety of both inheri

131 Extracellular release of oxidized mitochondrial DNA is proinflammatory in vitro, and when

132 Human mitochondrial DNA is transcribed by POLRMT with the help

133 iasis, HAT), contains a kinetoplast with the mitochondrial DNA (kDNA), comprising of >70% AT base pai

134 Diabetic D2 mice manifested increased mitochondrial DNA lesions (8-oxoguanine) exclusively loc

135 n synthesis mechanisms to bypass nuclear and mitochondrial DNA lesions.

136 Analysis of plasma mitochondrial DNA levels showed that TB-IRIS patients ex

137 ositively with monocyte casp1 expression and mitochondrial DNA levels, and expression of IL-18Ralpha

138 The Soave-Brazil pedigree of m.11778G>A/ND4 mitochondrial DNA LHON mutation.

139 o electron transport chain (ETC) poisons and mitochondrial DNA-linked disease mutations, yet how thes

140 analyses of NumtS derived from two different mitochondrial DNA loci allowed us to recognize the unusu

141 ad geographic range using microsatellite and mitochondrial DNA loci.

142 uced capacity for transport probably affects mitochondrial DNA maintenance and in turn respiration, c

143 migration suggest a dual role of TWINKLE in mitochondrial DNA maintenance.

144 Previous Y chromosome and mitochondrial DNA markers provided no support for their

145 Here we use microsatellite DNA and mitochondrial DNA markers to investigate the evolutionar

146 DNAm-age and mitochondrial DNA markers were measured from participant

147 e results demonstrate that the disruption of mitochondrial DNA metabolism elicits different responses

148 t cells respond differently to disruption of mitochondrial DNA metabolism.

149 nomenon for mitochondrial DNA: The levels of mitochondrial DNA methylation detected were higher in ex

150 a parental cell line, a Rho(0) line lacking mitochondrial DNA (mtDNA) and a Rho(0) line with restore

151 Changes in levels of mitochondrial DNA (mtDNA) and inflammation markers in pl

152 d patients with NASH contains high levels of mitochondrial DNA (mtDNA) and intact mitochondria and ha

153 ial reactive oxygen species and integrity of mitochondrial DNA (mtDNA) are crucial in breast cancer p

154 Studies of the Iceman have shown that his mitochondrial DNA (mtDNA) belongs to a novel lineage of

155 Mitochondrial DNA (mtDNA) biosynthesis requires replicat

156 In addition, loss of fusion and mitochondrial DNA (mtDNA) by deletion of mitochondrial o

157 ration sequencing (NGS) allows investigating mitochondrial DNA (mtDNA) characteristics such as hetero

158 potential link between circulating cell-free mitochondrial DNA (mtDNA) content and cancers.

159 Mitochondrial DNA (mtDNA) copy number and mtDNA deletion

160 Increased mitochondrial DNA (mtDNA) copy number in peripheral bloo

161 Mitochondrial DNA (mtDNA) copy number is a surrogate mea

162 Telomere length and mitochondrial DNA (mtDNA) copy number were measured from

163 accharomyces cerevisiae results in increased mitochondrial DNA (mtDNA) copy numbers, oxygen consumpti

164 tural/horticultural commodity trade data and mitochondrial DNA (mtDNA) cytochrome oxidase I (COI) and

165 RRK2 G2019S mutation carriers have increased mitochondrial DNA (mtDNA) damage and after zinc finger n

166 ality control via mitophagy, accumulation of mitochondrial DNA (mtDNA) damage and respiratory chain d

167 Mitochondrial DNA (mtDNA) damage is detrimental in ather

168 Bioenergetics and mitochondrial DNA (mtDNA) damage were assessed in single

169 Polbeta knockout (KO) had higher endogenous mitochondrial DNA (mtDNA) damage.

170 Accumulation of large-scale mitochondrial DNA (mtDNA) deletions and chronic, subclin

171 Mitochondrial DNA (mtDNA) deletions are associated with

172 Previously, we showed that partial mitochondrial DNA (mtDNA) depletion in different cell ty

173 Mammalian mitochondrial DNA (mtDNA) encodes 13 proteins that are e

174 Mitochondrial DNA (mtDNA) encodes RNAs and proteins crit

175 The hepatic mitochondrial DNA (mtDNA) failed to increase during reco

176 ses, from a variety of animals, in which the mitochondrial DNA (mtDNA) from one strain has been intro

177 e ability to rapidly quantify human-specific mitochondrial DNA (mtDNA) from raw untreated wastewater

178 To fill this gap, we analyzed ancient mitochondrial DNA (mtDNA) from Scythians of the North Po

179 Mitochondrial DNA (mtDNA) genes are long known to be cot

180 The accumulation of somatic mutations in mitochondrial DNA (mtDNA) has been hypothesized to be a

181 In recent years mitochondrial DNA (mtDNA) has transitioned to greater pr

182 otein, SWIB5, is capable of associating with mitochondrial DNA (mtDNA) in Arabidopsis thaliana Gain-

183 ication and reduced the degradation of tumor mitochondrial DNA (mtDNA) in DCs.

184 The levels of circulating mitochondrial DNA (mtDNA) in patients with AIS correlate

185 However, few studies have focused on mitochondrial DNA (mtDNA) in the cell free form.

186 Oxidative damage to mitochondrial DNA (mtDNA) in the retinal pigment epithel

187 ctive oxygen species (ROS), membrane damage, mitochondrial DNA (mtDNA) integrity, morphology, phenoty

188 s, shows a northwards gradient of increasing mitochondrial DNA (mtDNA) introgression from the arctic/

189 Mitochondrial DNA (mtDNA) is actively eliminated from th

190 Mitochondrial DNA (mtDNA) is essential for cell viabilit

191 Mitochondrial DNA (mtDNA) is essential for mitochondrial

192 Mitochondrial DNA (mtDNA) is typically inherited from on

193 read Nearctic chorus frog with six divergent mitochondrial DNA (mtDNA) lineages, many of which came i

194 pyrimidine salvage pathway, is essential for mitochondrial DNA (mtDNA) maintenance.

195 ematically evaluated five microbial and four mitochondrial DNA (mtDNA) markers, including sensitiviti

196 Populations of physiologically vital mitochondrial DNA (mtDNA) molecules evolve in cells unde

197 By causing mitochondrial DNA (mtDNA) mutations and oxidation of mit

198 Mitochondrial DNA (mtDNA) mutations and polymorphisms co

199 Mitochondrial DNA (mtDNA) mutations are a common cause o

200 Mitochondrial DNA (mtDNA) mutations are maternally inher

201 ed carrier frequency of 1:200, heteroplasmic mitochondrial DNA (mtDNA) mutations cause human disease

202 The accumulation of somatic mitochondrial DNA (mtDNA) mutations contributes to the p

203 Accumulation of mitochondrial DNA (mtDNA) mutations leads to alterations

204 otypic expression of primary LHON-associated mitochondrial DNA (mtDNA) mutations.

205 the phenotypic expression of LHON-associated mitochondrial DNA (mtDNA) mutations.

206 Mitochondrial DNA (mtDNA) often exists in a state of het

207 Human mitochondrial DNA (mtDNA) polymerase gamma (Pol gamma) i

208 Mitochondrial DNA (mtDNA) rearrangements are an importan

209 t) for species identification based on three mitochondrial DNA (mtDNA) regions amplified on DNA extra

210 biting platelet activation and extracellular mitochondrial DNA (mtDNA) release.

211 The mechanism of mitochondrial DNA (mtDNA) replication in Saccharomyces c

212 ntly, we now demonstrate that MTERF1 arrests mitochondrial DNA (mtDNA) replication with distinct pola

213 This was tested using a major mitochondrial DNA (mtDNA) survey and sequencing of two n

214 DNA in infected cells through the release of mitochondrial DNA (mtDNA) to drive the production of cGA

215 ever, the closer affinity of the Neanderthal mitochondrial DNA (mtDNA) to modern humans than Denisova

216 s of cultured cells indicates that mammalian mitochondrial DNA (mtDNA) tolerates such replication err

217 d respiration and enhanced glycolysis, while mitochondrial DNA (mtDNA) transcripts were decreased, wi

218 in the PD-mito-PstI mouse (males), where the mitochondrial DNA (mtDNA) undergoes double-strand breaks

219 heteroplasmy, the presence of more than one mitochondrial DNA (mtDNA) variant in a cell or individua

220 horylation in patients with ASD, the role of mitochondrial DNA (mtDNA) variation has remained relativ

221 Alterations in mitochondrial DNA (mtDNA) were once thought to be predom

222 ed following incubation of HOS cells lacking mitochondrial DNA (mtDNA) with functional exogenous mito

223 f this mitochondrial respiration, can damage mitochondrial DNA (mtDNA), and somatic mtDNA mutations h

224 ns, deletions, and changes in copy number of mitochondrial DNA (mtDNA), are observed throughout cance

225 een investigated by sequencing autosomal and mitochondrial DNA (mtDNA), but large-scale sequence anal

226 Mitochondrial DNA (mtDNA), encoding 13 out of more than

227 mitochondrial injury, such as extracellular mitochondrial DNA (mtDNA), have not been identified in I

228 ia also contain a small circular genome, the mitochondrial DNA (mtDNA), that encodes 13 polypeptides.

229 ntrast with phylogeographic studies based on mitochondrial DNA (mtDNA), which have been interpreted a

230 The synthesis of all 13 mitochondrial DNA (mtDNA)-encoded protein subunits of th

231 affect one of 38 nuclear-encoded subunits, 7 mitochondrial DNA (mtDNA)-encoded subunits or 14 known C

232 are frequently associated with mutations in mitochondrial DNA (mtDNA).

233 from oxidative stress through maintenance of mitochondrial DNA (mtDNA).

234 sequencing usually include reads containing mitochondrial DNA (mtDNA).

235 usands of copies of the maternally inherited mitochondrial DNA (mtDNA).

236 ce suggests presence of methylation marks on mitochondrial DNA (mtDNA); but their contribution in can

237 oreover, mitochondria have their own genome (mitochondrial DNA [mtDNA]).

238 ell lines derived from a Chinese family into mitochondrial DNA(mtDNA)-less (rho(o)) cells, we demonst

239 Mitochondrial genomes (mitochondrial DNA, mtDNA) encode essential oxidative pho

240 The mitochondrial DNA mutation m.1555A>G predisposes to hear

241 The m.3243A > G mitochondrial DNA mutation was originally described in p

242 We performed mitochondrial DNA mutational mapping studies to determin

243 In farm animals, mitochondrial DNA mutations exist widely across breeds a

244 se models, suggest that accumulating somatic mitochondrial DNA mutations may cause the phenotypic cha

245 tating conditions resulting from nuclear and mitochondrial DNA mutations that affect multiple organs,

246 In cells carrying patient-derived mitochondrial DNA mutations, the xCT antiporter is upreg

247 s an approach to rescue defects arising from mitochondrial DNA mutations.

248 the greatest emphasis on diseases caused by mitochondrial DNA mutations.

249 ; dystonia was predominantly associated with mitochondrial DNA mutations.

250 ETO-induced increase in mitochondrial mass, mitochondrial DNA (ND1 and ND4) copy number, intracellul

251 cture enabling mixing of previously discrete mitochondrial DNA nucleoids.

252 Mutations in mitochondrial DNA occur in oncocytic thyroid tumors, but

253 tide sequencing analysis, and found to carry mitochondrial DNA of the Neandertal type.

254 As a result of DNA damage, mitochondrial DNA or nuclear DNA has been shown to enter

255 se findings were not explained by defects in mitochondrial DNA or transcription.

256 further corroborates the interdependence of mitochondrial DNA organization and cholesterol.

257 se H1 and RNA in the physical segregation of mitochondrial DNA, perturbation of which represents a pr

258 itochondrial transcription factors including mitochondrial DNA pol gamma and Twinkle contribute to SC

259 ddC is a selective inhibitor of the mitochondrial DNA polymerase gamma.

260 emplate and prime DNA synthesis by the yeast mitochondrial DNA polymerase Mip1.

261 New work shows that the mitochondrial DNA polymerase, which normally replicates

262 Additionally, we also assayed mitochondrial DNA polymorphisms among ancient Parsi DNA

263 etaand nuclear respiratory factor 1 mRNA and mitochondrial DNA quantification.atRA also increasedbeta

264 of the appropriate specific fragments of the mitochondrial DNA region and capture probes.

265 revents the degranulation of neutrophils and mitochondrial DNA release required for NET formation.

266 A repair complex assembly, thereby enhancing mitochondrial DNA repair capacity.

267 fhydration of EXOG, which, in turn, promotes mitochondrial DNA repair complex assembly, thereby enhan

268 uggest that, contrary to nuclear DNA repair, mitochondrial DNA repair is not able to compensate for A

269 ung epithelial cells elevated H2S stimulates mitochondrial DNA repair through sulfhydration of EXOG,

270 XOG) is a 5'-exonuclease that is crucial for mitochondrial DNA repair; the enzyme belongs to a nonspe

271 nslocases and a dramatic accumulation of the mitochondrial DNA replication and maintenance factors PO

272 of the mitochondrial DNA content, and of the mitochondrial DNA replication and transcription factor T

273 ygen consumption rates and modestly reducing mitochondrial DNA replication priming.

274 of preimplantation development, and promoted mitochondrial DNA replication prior to embryonic genome

275 ondrial R-loop processing, transcription and mitochondrial DNA replication.

276 DGUOK, a deoxyguanosine kinase required for mitochondrial DNA replication; haplotype sharing demonst

277 Ribonuclease H1 is essential for mitochondrial DNA replication; it degrades RNA hybridize

278 tions in the c10orf2 gene encoding the human mitochondrial DNA replicative helicase Twinkle are linke

279 A crucial component of the human mitochondrial DNA replisome is the ring-shaped helicase

280 was associated with an increased release of mitochondrial DNA, resulting in Aim2 and NLRC4 inflammas

281 We report ancient mitochondrial DNA results of 213 individuals (151 HVS-I

282 Additional analyses of ancient and modern mitochondrial DNA revealed a sharp discontinuity in hapl

283 Here, we report that inducible depletion of mitochondrial DNA (rho(omicron) cells) diminished respir

284 Integration of D. sibiricus mitochondrial DNA sequences and the spread of this speci

285 y Delphacinae based on nuclear ribosomal and mitochondrial DNA sequences of four genetic loci (16S rD

286 Complete mitochondrial DNA sequences were isolated and used to in

287 mans are flanked by short, directly repeated mitochondrial DNA sequences; however, the mechanism of s

288 quiescent cells where it provides dNTPs for mitochondrial DNA synthesis.

289 Mitochondrial DNA that shows similarities to bacterial D

290 We found a similar phenomenon for mitochondrial DNA: The levels of mitochondrial DNA methy

291 y a single maturase has been retained in the mitochondrial DNA: the matR gene found within NADH dehyd

292 Here, we used nuclear and mitochondrial DNA to infer the phylogeographic and evolu

293 ructs the evolutionary process of horizontal mitochondrial DNA transfer and enables modification of t

294 Thus, rare mitochondrial DNA transfer from N. sylvestris to N. taba

295 ng of cytochrome c oxidase I (COI) region of mitochondrial DNA was used to characterize the genetic d

296 Using targeted enrichment of mitochondrial DNA, we show that cave sediments represent

297 lexes I, III, and IV, encoded by nuclear and mitochondrial DNA, were abnormally low, whereas activity

298 NA accumulation triggers cytosolic escape of mitochondrial DNA, which engages cGAS.

299 orresponding ribonucleotides incorporated in mitochondrial DNA, while in nuclear DNA the ribonucleoti

300 Herein we combine information from mitochondrial DNA with physical and environmental featur