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1 ay due to promoting robust activation of the mitotic spindle checkpoint.
2 kinase believed to function primarily in the mitotic spindle checkpoint.
3 ibition of APC in U2OS cells compromises the mitotic spindle checkpoint.
4  a cell-cycle surveillance system called the mitotic spindle checkpoint.
5 B, which encodes BUBR1, a key protein in the mitotic spindle checkpoint.
6 nduces genomic instability by subverting the mitotic spindle checkpoint.
7 ed as encoding proteins that function at the mitotic spindle checkpoint.
8 ptor-positive tumors and associated with the mitotic spindle checkpoint.
9 ondensation, chromosome segregation, and the mitotic spindle checkpoint.
10 ed as encoding proteins that function at the mitotic spindle checkpoint.
11  mechanism of aneuploidy not detected by the mitotic spindle checkpoint.
12 azole, showed that EBNA3C could abrogate the mitotic spindle checkpoint.
13  both the G1/S cell cycle checkpoint and the mitotic spindle checkpoint.
14  p53 has been identified as a component of a mitotic spindle checkpoint.
15 han a general role of the APC protein in the mitotic spindle checkpoint.
16 d promoted bypass of the G(2) DNA damage and mitotic spindle checkpoints.
17 ls overexpressing Pim-1 have a defect in the mitotic spindle checkpoint, abnormal mitotic spindles, c
18                    They also had inactivated mitotic spindle checkpoint activities since they did not
19 otein phosphatase 2A, has been implicated in mitotic spindle checkpoint activity and maintenance of s
20  Exposure of cells to colcemid activates the mitotic spindle checkpoint and arrests cells transiently
21 ression of genes involved in maintaining the mitotic spindle checkpoint and genomic stability, e.g.,
22  Other p53-dependent properties, such as the mitotic spindle checkpoint and permissivity for gene amp
23                       In cells lacking KIF4, mitotic spindle checkpoints and DNA-damage response path
24 rturbations of the G(1)-to-S, G(2)-to-M, and mitotic spindle checkpoints are discussed.
25 f is important for spindle formation and the mitotic spindle checkpoint arrest.
26 o evaluate the potential role of a defective mitotic spindle checkpoint as a cause of this chromosoma
27 ion defects strictly depends on a functional mitotic spindle checkpoint as well as on intact microtub
28      The metaphase arrest is mediated by the mitotic spindle checkpoint being dependent on Mad1 and t
29 xpression of MDM2 contributes to the loss of mitotic spindle checkpoint control in the E7 cells.
30 with a genomic instability consistent with a mitotic spindle checkpoint defect.
31                       Notably, the extent of mitotic spindle checkpoint deficiency and chromosome num
32              In addition, genes required for mitotic spindle checkpoint function and for normal micro
33 16, although these cells displayed defective mitotic spindle checkpoint function associated with inac
34 atocyte culture or transgenic mice inhibited mitotic spindle checkpoint function because of reduced R
35  this does not seem to be due to compromised mitotic spindle checkpoint function.
36                                          The mitotic spindle checkpoint is thought to play a major ro
37                BUBR1, a key component of the mitotic spindle checkpoint, is a multidomain protein kin
38 asmic dynein, and proteins involved with the mitotic spindle checkpoint, Mad2, Bub1R, and the 3F3/2 p
39 crotubules, generate force, and activate the mitotic spindle checkpoint may all depend on microtubule
40  In this study, we develop evidence that the mitotic spindle checkpoint molecule BUB1B may offer a pr
41                                          The mitotic spindle checkpoint monitors proper bipolar attac
42 y, this study clarifies the role of APC as a mitotic spindle checkpoint protein in vivo and shows tha
43 so has an evolutionarily conserved role as a mitotic spindle checkpoint protein.
44 arrest deficiency 2 (Mad2) is a component of mitotic spindle checkpoint proteins and is essential for
45 DNA damage checkpoint, but not bypass of the mitotic spindle checkpoint, required activation of mitog
46                 Dysfunctional DNA damage and mitotic spindle checkpoints resulting from these interac
47 eins are regulated during the cell cycle and mitotic spindle checkpoint signaling.
48 inase is required for proper assembly of the mitotic spindle, checkpoint signaling, and several other
49 hts the role of spatiotemporal regulation in mitotic spindle checkpoint signalling and fidelity of ch
50                    Furthermore, this altered mitotic spindle checkpoint status was associated with th
51 sion activate a signaling pathway called the mitotic spindle checkpoint that blocks progression into
52 that increased AuroraA levels compromise the mitotic spindle checkpoint triggered by nocodazole, a mi
53 highlights the role of MK2 in G(2)/M and the mitotic spindle checkpoints, two mechanisms by which MK2
54                 This ability to override the mitotic spindle checkpoint was found to be independent o
55 duced G(2) arrest, RAS-induced bypass of the mitotic spindle checkpoint was not prevented by pretreat
56 ls of chromosomal instability have defective mitotic spindle checkpoints, whereas the cell lines with
57              However, Tax did not affect the mitotic spindle checkpoint, which was also functional in
58  flow cytometric analysis, we found that the mitotic-spindle checkpoint, which helps maintain chromos

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