ライフサイエンスコーパス: moderate effect

1 r videotaping for supervision demonstrated a moderate effect.

2 by the accumulation of multiple mutations of moderate effect.

3 eparin binding, although change at R46 has a moderate effect.

4 eptor-gamma activator ciglitazone had only a moderate effect.

5 oxicam and difluoromethylornithine exerted a moderate effect.

6 o result from the action of several genes of moderate effect.

7 mutating Asn-154, Asp-219, and His-258 had a moderate effect.

8 any coding low-frequency alleles (1-5%) with moderate effect.

9 osition, whereas dietary changes have only a moderate effect.

10 hey do not allow for interactions and QTL of moderate effect.

11 F-kappa B site in the IL-2 promoter has only moderate effects.

12 sizes may identify coding variants with more moderate effects.

13 Gender did not moderate effects.

14 ected by many genetic variants with small or moderate effects.

15 rigorous studies there were similar small-to-moderate effects.

16 ation of this residue to Trp or Tyr had only moderate effects.

17 Age, body mass index (BMI) and gender had no moderating effects.

18 activity, both compounds 11 and 12 displayed moderate effects against H2O2-induced neurotoxicity in P

19 ch suggested the presence of single genes of moderate effect, although in several other regions, sign

20 The majority of QTL have low to moderate effects, although a few QTL exist in A. socius

21 e with pre-existing iron overload had a more moderate effect and caused partial redistribution of iro

22 perimental populations, allowing for eQTL of moderate effect and interactions.

23 ticularly useful when variants in a set have moderate effects and are difficult to be detected with s

24 feedback (SMD = 0.58; 95% CI, 0.10-1.07) had moderate effects; and moulage had a small effect (SMD =

25 s due to the inability to detect variants of moderate effect ( approximately 0.03-0.3 phenotypic SDs)

26 Our findings point to multiple loci with moderate effects associated with susceptibility to prost

27 nstrated increased power for WGS variants of moderate effect, but when larger genetic effects were pr

28 etween 3.4% and 7.6% (P < 0.05), which was a moderate effect compared with that of risedronate at 15.

29 eumonia infection in the mouse and displayed moderate effects compared with a control antibiotic, gen

30 Deletions of degU, comA, and scoC had moderate effects, disrupting the timing and level of pks

31 cohort, the Cohen d results showed small to moderate effects (effect sizes > 0.2) of several variabl

32 ons, these compensatory responses had strong moderating effects even after losing many species.

33 The eta2 value of 0.124 suggested a moderate effect favoring the diazepam treatment.

34 omes of knowledge, skills, and behaviors and moderate effects for patient-related outcomes.

35 on of cholesterol in these vesicles has only moderate effects for phospholipids at temperatures above

36 There was no moderating effect for age, comorbidity, gender, year of

37 We found no evidence of a moderating effect for two other, less well-studied SNPs

38 ch is inhibited by XIAP although it exerts a moderate effect in conventional T cells.

39 combination of genes, each having a small to moderate effect in increasing ASD risk.

40 Thus, there may exist a gene of moderate effect in this region.

41 linical studies stands in contrast with only moderate effects in clinical Phase II-III trials.

42 ce self-consciousness was exacerbated by the moderating effect increased salience of appearance.

43 ty is very pronounced at 39 degrees C, but a moderate effect is noted even at 33 to 34 degrees C.

44 sment of such multicomponent approaches with moderate effects is difficult.

45 nvironmental and multiple genetic factors of moderate effect, is more likely than an aetiology consis

46 dvanced-intercross population, mapping three moderate-effect loci contributing to trait heritability.

47 We found 17-34 minor- or moderate-effect loci that influence ear traits, with lit

48 their power to detect genes having small to moderate effects may be greater than that of other linka

49 heterogeneity, multiple genes with small to moderate effects may influence susceptibility to diabete

50 ture, while defense metabolism was more of a moderate-effect model.

51 A moderate effect of increased atmospheric CO2 on water us

52 in Los Angeles homes was too low to detect a moderate effect of the magnitude reported in other studi

53 men suggests that the obese state may mask a moderate effect of the Trp64Arg variant on energy expend

54 ith the mutations W1408R and R1640W showed a moderate effect of these individual mutations on express

55 found common regulatory variation in MAOA to moderate effects of childhood maltreatment on male antis

56 These findings are compatible with modest to moderate effects of sleep-disordered breathing on hetero

57 ontrast, the reliable assessment of any more moderate effects of treatment on major outcomes--which a

58 ntal control, OPRM1 A118G variation robustly moderates effects of opioid antagonism on alcohol reward

59 Recent reports of a moderating effect of a genetic polymorphism (5-HTTLPR) i

60 There was a significant moderating effect of baseline total number of cocaine us

61 nd risks of stress ulcer prophylaxis and the moderating effect of enteral nutrition.

62 We investigated the moderating effect of media use on the relationship betwe

63 We examined the moderating effect of occupational grade on the associati

64 ients with major depression and examined the moderating effect of patients' treatment preferences on

65 od socioeconomic disadvantage as well as the moderating effect of positive parenting on adolescent br

66 tressors and mental health, and assessed the moderating effect of post-migration stressors in humanit

67 at young adult age, along with the potential moderating effect of prenatal exposure to methylmercury.

68 EDS), we attempted to replicate the reported moderating effect of SES on children's intelligence at a

69 effect of SES on intelligence, as well as a moderating effect of SES on the genetic and environmenta

70 No moderating effects of age at time of childhood assessmen

71 ics on stroke risk were estimated, while the moderating effects of age, sex, presence of dementia, an

72 ained significant after evaluating potential moderating effects of between-group differences in basel

73 on processing in adults over 80 and examined moderating effects of chronic diseases and physical acti

74 Moderating effects of chronic diseases and physical acti

75 ts with Child-Pugh class B cirrhosis and any moderating effects of health system characteristics are

76 Moderating effects of mean age, mean physical disability

77 The moderating effects of self-consciousness should be consi

78 Weaker moderating effects of sex were scattered along the mesia

79 No moderating effects of single or recurrent major depressi

80 graphic and disease-related factors, but the moderating effects of these psychosocial factors were li

81 toms compared with controls and evaluate the moderating effects of treatment outcome and response.

82 gression models were used to investigate the moderating effects of VS reactivity on the relationship

83 the ligand, and of the alpha-helix, had more moderate effects, often with the affinity for some induc

84 tions at the terminal loop of the stem had a moderate effect on activity but no effect on cleavage si

85 tide can be reduced to 14 residues with only moderate effect on binding affinity.

86 moving it proximal to these sites had only a moderate effect on catalysis.

87 Although MEIS1 alone has only a moderate effect on cell proliferation in vitro, it is es

88 We identified a QTL of moderate effect on chromosome 7 that affected 2f1-f2 emi

89 retory vesicles, GTP-bound Rab11b only had a moderate effect on constitutive secretion and no effect

90 9K, I54T, G169R, and S252I, which have no or moderate effect on DNA-binding activity and the function

91 PP2, an inhibitor of SFK, had a moderate effect on EGFR internalization in several types

92 Integrin activation had a moderate effect on enhancing retinal pigmented epithelia

93 ed PKC/Ras-mediated apoptosis but had only a moderate effect on Fas-induced apoptosis.

94 Changes in the trade structure had a very moderate effect on global emissions (+0.6 Gt).

95 acrophage colony-stimulating factor had only moderate effect on hCCR2 expression.

96 58035 had a moderate effect on IL-8 induction by acLDL.

97 Mre11 eliminates Rad50 binding but only has moderate effect on its intrinsic nuclease activity; howe

98 Ionic strength (micro) had a moderate effect on k(assn) in a manner predictable based

99 taining the hly ribosome binding site, had a moderate effect on LLO production during growth in broth

100 red by G-protein-coupled receptors and had a moderate effect on neutrophil responses triggered by mic

101 We find that torque has only a moderate effect on nucleosome unwrapping.

102 eoclast formation and function, they exert a moderate effect on osteoclast survival.

103 the treatment of ALS, Riluzole, has at best, moderate effect on patient survival and quality of life;

104 s life (GQ = 1, n = 611); DLQI scores 6-10 = moderate effect on patient's life (GQ = 2, n = 327); DLQ

105 es on the mature sepal epidermis, but only a moderate effect on petal cone cell ridges.

106 ctopic expression of either gene alone has a moderate effect on pronephric patterning, while coexpres

107 except for risperidone, which had a small-to-moderate effect on quality of life (g = 0.49).

108 s being critical for DNA binding, had only a moderate effect on the DNA-binding activity of XPA.

109 ted increase in the Egr1 mRNA but has only a moderate effect on the Egr1 protein.

110 ugh the Met(20) loop conformation only has a moderate effect on the hydride transfer rate and donor-a

111 pophilic piperidine ring appears to confer a moderate effect on the liver uptake of these two chelate

112 eatment with EGCG and tobramycin, EGCG had a moderate effect on the minimum bactericidal eradication

113 ompound specific monoterpene emissions has a moderate effect on the modeled global CCN budget.

114 t that an experimental AM-rEPA vaccine has a moderate effect on the numbers of CFU in organs early af

115 tion of enzyme substrates or imidazole has a moderate effect on the rate of the ligand switch, but do

116 ethylene glycol (PEG), 20kDa or 40kDa, had a moderate effect on the residence time of an anti-IL-17A

117 contrast, carriers of the T allele showed a moderate effect on the risk of NAFLD (odds ratio: 2.13;

118 n yeast cells had either no effect or only a moderate effect on the specific methyltransferase activi

119 s in the vicinity of an acylation site had a moderate effect on the stearate content.

120 in MPP(+)-treated cells and produced only a moderate effect on the survival of dopaminergic neurons

121 and Th2 cytokines, while free CpG had only a moderate effect on these parameters.

122 Intetumumab alone had a moderate effect on tumor growth.

123 ide immunization of tumor-bearing mice had a moderate effect on tumor regression.

124 a receptor was less effective, having only a moderate effect on white blood cell infiltration and no

125 significant QTL on chromosome 9 (Hfhl3) with moderate effects on 2f1-f2 emissions intensities.

126 For comparison, NMDA antagonists had only moderate effects on all ganglion cell light-responses.

127 We observed that most mutations had moderate effects on amiloride block, whereas those intro

128 NTCP inhibition using myrcludex B had only moderate effects on bile acid kinetics in WT mice, but c

129 didate genes that consistently show small to moderate effects on brain measures.

130 Despite the moderate effects on energy balance and independent of ch

131 ptophan with phenylalanine or isoleucine has moderate effects on enzyme affinity for surfaces but yie

132 of the cytokine receptor family had small to moderate effects on EPO binding.

133 Among them, ZCN1 showed moderate effects on flowering time and tassel morphology

134 stems by having a balancing function through moderate effects on gene expression levels.

135 cation of HOTAIR expression evoked only very moderate effects on gene expression, particularly of pol

136 ibit a distinct phenotype in vivo) have only moderate effects on global nucleosome structure.

137 one binding, while deletion of Cac3 has only moderate effects on H3-H4 binding and nucleosome assembl

138 23G, or P123F) producing viable enzymes with moderate effects on in vitro ATP hydrolysis or proton tr

139 In the short term, only moderate effects on LV pump function were observed despi

140 nificant impact on survival end points; only moderate effects on outcome were found, depending on mol

141 had a significant effect on infectivity and moderate effects on pathogenicity.

142 single deficiency of SLAP or SLAP2 had only moderate effects on platelet function, whereas double de

143 regulation of basal resistance, having only moderate effects on PR gene expression.

144 ation of retinal ganglion cell axons, it has moderate effects on retinal morphology and function.

145 e at improving functional communication with moderate effects on social communication.

146 NSBBs had only moderate effects on systemic hemodynamics at patients' f

147 tution of Y577, Y724, or Y770 had minimal to moderate effects on TDII-dependent transformation.

148 ions decrease the association rate with only moderate effects on the dissociation rate, suggesting th

149 the unfolding of the kissing complex but has moderate effects on the formation kinetics of the struct

150 t to identify genetic variants with small to moderate effects on the JIA phenotype.

151 While the Y305A mutation had moderate effects on the kinetics of catalysis (2.5- and

152 re was no effect on the Km of dUMP, and only moderate effects on the Km of the cofactor.

153 e potential of Ag-specific CD8+ T cells with moderate effects on their differentiation to effector an

154 Substitutions at positions 6, 20, and 21 had moderate effects on Tus-Ter interactions, suggesting tha

155 the conserved scaffold is shown to have only moderate effects on unnatural self-pair synthesis by the

156 However, HPA axis reactivity has a moderating effect on IBS symptoms.

157 sate profiles, with aspirin having a general moderating effect on the amount of protein released rega

158 pacing stochasticity was found to sustain a moderating effect on the APDR curve by reducing its slop

159 oticism nor extraversion was shown to have a moderating effect on the relationship between dispositio

160 Research into moderating effects on cortisol coregulation suggests str

161 owed that age, gender and sample size had no moderating effects on the outcome of the meta-analysis,

162 the eta2 value of 0.135 for time suggested a moderate effect over time within-subjects.

163 equate statistical power to detect small and moderate effects, phenotype heterogeneity, population st

164 oma tigrinum complex) carry alleles at three moderate effect QTL (met1-3) that vary in responsiveness

165 es suggesting that there are many genes with moderate effects rather than a few major genes.

166 cross the genome, which each have a small to moderate effect, rather than from a few loci that each h

167 t to have enough power to detect siRNAs with moderate effects, sample size needs to be 8, 9, 10 or 11

168 The magnitude of benefit was moderate (effect size of 0.5 to 0.8, improvement of 10 t

169 lpha=0.99) and responsiveness was clinically moderate (effect size=0.51).

170 , 95% CI -0.22 to -0.06; p=0.001), showing a moderate effect size (beta -0.44, 95% CI -0.60 to -0.29;

171 ial treatments provide benefits reflecting a moderate effect size according to Cohen's standards.

172 er, it remains unclear whether variants with moderate effect size and frequencies below what are reli

173 (GWASs) have identified a genetic variant of moderate effect size at 6p21.1 associated with erythrocy

174 included, the analysis indicated a small-to-moderate effect size for advertising on food consumption

175 cond sample, further excluding variants with moderate effect size.

176 association methods to detect risk genes of moderate effect size.

177 an association between E117G and ALS, with a moderate effect size.

178 academic scores 2 years later, with small to moderate effect sizes ( vertical liner vertical line= 0.

179 hypothesized that common polymorphisms with moderate effect sizes and large attributive risks could

180 nightmares, sleep, and PTSD (all P<.02) with moderate effect sizes for treatment (mean Cohen d = 0.60

181 These estimated differences correspond to moderate effect sizes in favour of PM+ for GHQ-12 score

182 st effect sizes, whereas those with small or moderate effect sizes modify phenotypic expression of th

183 aining in this treatment was associated with moderate effect sizes.

184 power to detect common genes with a small-to-moderate effect, so long as the same gene has an effect

185 and F(2)s flowered, and six QTLs of small to moderate effect were revealed, with underlying candidate

186 Small to moderate effects were found for global cognition, attent

187 Moderate effects were observed on HIPA removal.

188 Moderate effects were observed with substitutions at pos

189 Moderate effects were recorded in Padak, an area with hi

190 Moderating effects were tested using hierarchical regres

191 vast majority of metabolic QTLs had small to moderate effects with significant polygenic epistasis.

192 Several studies found moderating effects with PTE and genetic susceptibilities