ライフサイエンスコーパス: modest

1 gement Guideline in cardiology practices was modest.

2 s, changes in membrane parameters tend to be modest.

3 ess, its efficacy in those without MTS seems modest.

4 s reduced, albeit both of these effects were modest.

5 of precise temporal coding is comparatively modest.

6 ining in focused cardiac ultrasonography was modest.

7 -hospital mortality and 30-day mortality was modest.

8 ediators; however, the observed response was modest.

9 CSF biomarkers at baseline showed a more modest (0.3%, 95% CI 0.1-0.5) but still significant effe

10 mass-specific muscular performance is a more modest 1.5 times greater than humans on average.

11 ted that mmpT5 mutations are associated with modest 2- to 8-fold increases in MICs for BDQ and clofaz

12 king capacity (2.42 mmol/g, 9.1 wt %) with a modest 60 degrees C temperature swing.

13 ociated with a statistically significant but modest absolute improvement in survival (hazard ratio 0.

14 odomains were calculated and returned a more modest accuracy (mean unsigned error of 1.76 kcal/mol an

15 th, low and high-replicative HBV demonstrate modest accuracy for fibrosis diagnosis at conventional c

16 ent of hospitalizations can be achieved with modest accuracy.

17 diction models of pediatric asthma have only modest accuracy.

18 man DUX4 expressed in mouse cells maintained modest activation of cleavage-stage genes driven by conv

19 Ibrutinib is a well-tolerated treatment with modest activity in relapsed FL.

20 The modest activity of the starting enzyme was previously im

21 (5) -((15c5) NCOP(iPr) )Ir(H)](+) exhibiting modest activity.

22 Modest adverse events related to Opra Kappa included pru

23 d that the CRD binds to monosaccharides with modest affinity and that affinity was greatly enhanced f

24 In addition, (123)I-FP-CIT has modest affinity for the serotonin transporter (SERT), pr

25 an and found compound (28f), a selective but modest affinity MOR antagonist weaker than alvimopan (1)

26 used to make this assessment, but relatively modest agreement among practitioners supports the use of

27 There is only modest agreement between Td and eFick CI estimates.

28 Even achieving the modest Aichi Target 11 of 10% "effective protection" can

29 We studied long-term effects of modest alcohol use on fibrosis progression in a large co

30 n Glc-supplemented cells was correlated with modest alterations (approximately 2x) in the levels of s

31 This modest amino acid alteration, the mere removal of a pair

32 easurements, treatment efficacy is generally modest and differences in efficacy between antidepressan

33 ever, the improvement in overall survival is modest and only in combination with chemotherapy.

34 ion; generally, their estimated effects were modest and waned over time.

35 (11)C-nicotine administration is relatively modest and would allow for multiple PET examinations on

36 The analgesic effects of BMAs are modest, and they should not be used alone for bone pain.

37 Such tetani caused a modest AP decrease, to a similar extent for both types o

38 However, the realized valley splitting is modest ( approximately 0.2 meV T(-1)).

39 eased permeability, which was augmented by a modest (approximately 40%) increase in hydrostatic press

40 We observed a modest association between ingestion of water with highe

41 5059]) at 6 to 12 months as well as small-to-modest associations with dietary and physical activity b

42 her IOP in this study, the associations were modest at best.

43 explained by environmental conditions, from modest at small scales (R(2) = 0.34) to strong at large

44 ty, whereas cooked vegetable intake showed a modest benefit against mortality.

45 Screening colonoscopy may have had a modest benefit in preventing CRC in beneficiaries aged 7

46 Folic acid supplementation confers modest benefit in schizophrenia, but its effectiveness i

47 cardiovascular disease result in consistent modest benefits across a variety of important intermedia

48 At 3 months, guided self-help demonstrated modest benefits over the waiting list in reducing OCD sy

49 and LVSD of varying etiologies have reported modest benefits with a rhythm control strategy.

50 exercise had significant, albeit clinically modest, benefits on body weight, fat mass, and markers o

51 ed voxels to be approximately random, with a modest bias toward more foveal voxels.

52 Modest blood pressure increases seen in TRAFFIC and TRAN

53 monstrate that treatment strategies offering modest but continual enhancement of reservoir clearance

54 Il4-hemizygosity also resulted in a modest but detectable drop in IL-4 production by CD4(+)

55 ence, and that ST-SPI diet early in life has modest but persistent programming effects on bone format

56 Our Trans-Omics analyses reveal a modest but potentially relevant pervasive up-regulation

57 nes for variant classification, identified a modest but realistic yield in SADS.

58 Intra- and interspecific identity had modest but significant effects on plant and fungal produ

59 Our results suggest that: 1) There is a modest but significant improvement in systolic BP in ran

60 ng between 2006 and 2012 was associated with modest but significant reductions in prescribing of deta

61 ngle prostanoid receptor typically exhibited modest but statistically significant inhibition, AGN 211

62 ATION: Palliative chemoradiotherapy showed a modest, but not statistically significant, increase in d

63 initially present on native-like ions have a modest, but sometimes statistically significant, effect

64 djusted linear regression analyses indicated modest, but statistically significant, average annual pe

65 Modest c-Jun elevation, which is beneficial for regenera

66 n transcription is associated with a similar modest change in hepatitis B virus core antigen polypept

67 (SOZ), which are known skin irritants, and a modest change in particle size.

68 trochemical properties could be tuned over a modest change of temperature (i.e., 20-40 degrees C).

69 INTERPRETATION: Modest changes in diets could help to address projected

70 ly different kinetic regimes are affected by modest changes in gas pressure.

71 7-PABPN1 and detected shorter poly(A) tails, modest changes in poly(A) signal (PAS) usage, and eviden

72 network chains to be varied 500-fold through modest changes in protein sequence.

73 By late century, we found modest changes in the spatial distribution of dominant s

74 ating an A205P substitution, suggesting that modest changes in TraA can lead to diversification of ne

75 eral Trailblazer genes shows significant but modest changes to total distance migrated.

76 g, had a single place field, and showed only modest changes when the mouse was tested in different ma

77 tly attenuates the hypoxic response, even at modest CITED2 concentrations.

78 elivery via electroporation, yet it remained modest compared with Ad5.

79 tection in animal models of HIV infection at modest concentrations, inspiring efforts to develop an H

80 adaptation renders mouse rods responsive to modest contrast at any irradiance.

81 Reverse triage adds a meaningful but modest contribution and may depend on psychiatric space.

82 We also found a more modest contribution from the positively charged Arg-1119

83 aries, where they are short lived and make a modest contribution to glomerular injury.

84 ats exploring a novel environment, despite a modest correlation found for the centrality and hubness

85 There were modest correlations between COPD readmission rates and r

86 This relationship was due to modest correlations between NET complexes and FEV1, symp

87 arious atmospheric circulations yielded only modest correlations, leaving the relative importance of

88 Although alum-adjuvanted vaccines induced modest costimulatory molecule expression, limited TH-pol

89 heterologous prime-boost vaccination induced modest cross-reactive HI antibody responses to H5Nx viru

90 unadjusted trend, with a slight increase and modest decline (22.2%) in VCF placement rates over time;

91 ient survival curve with neither mutation, a modest decline in the curve with either mutation alone,

92 optical depth has not increased (but shows a modest decline) over this period, suggesting the decline

93 In summary, although modest declines in neurocognitive performance were seen

94 With Dox, there was a sustained, modest decrease in LVEF over the follow-up duration (1-y

95 intake.Greater height was associated with a modest decrease in the likelihood of healthy aging.

96 production, and immunoglobulin levels and a modest decrease in the phagocytic capacity of pulmonary

97 Very modest decreases in G4 DNA-stimulated ATPase activity we

98 Most of these mutants have modest defects in the assembly of the spore protective l

99 In this trial, which resulted in a modest degree of protection, ADCC responses were identif

100 variability in PFAS concentrations to only a modest degree.

101 scle biopsies from individuals who underwent modest dietary restriction coupled with exercise also di

102 ascular events, leading to overall similarly modest discriminatory abilities of both tests.

103 general recommendations include: (1) low to modest dosages of tricyclic antidepressants provide the

104 cubated with diseased cells, we only found a modest down regulation in prostanoid concentrations, whe

105 This is due to modest drug concentrations inside caseum and high inhibi

106 redominant role played by common variants of modest effect and the diversity of biological mechanisms

107 ng hexosamine biosynthetic pathway, but this modest effect did not fully account for the change in N-

108 A modest effect of DHA + aspirin on Porphyromonas gingival

109 The large amount of food given and the modest effect on linear growth in newborns suggests that

110 of HAdV-C5 in the liver, while it has only a modest effect on the replication of HAdV-C6.

111 dual residues implicated in G4 binding had a modest effect on WRN binding to DNA, decreasing the pref

112 is not broadly generalisable, but must be of modest effect size and only observable in limited situat

113 Due to modest effect sizes, large sample sizes of tens to hundr

114 (2+) has no effect with 100 nm liposomes and modest effect with giant unilamellar vesicles.

115 decreases in cholesterol levels have only a modest effect.

116 Considering their modest effectiveness in dementia patients, the increased

117 verse outcomes, whereas Kineret exerted only modest effects and no benefit for gestation length, neon

118 back pain, and duloxetine is associated with modest effects for chronic low back pain.

119 nexpectedly, the switch I mutations had only modest effects on GTP binding and on GTPase activity and

120 re state-managed invertebrate fisheries, but modest effects on the groundfish fishery because individ

121 o not incorporate to full occupancy and have modest effects on virus replication and pathogenesis.

122 Single-agent selinexor showed modest efficacy with an objective response rate (ORR) of

123 tiety-inducing obesity therapeutics, despite modest efficacy, have safety concerns that underscore th

124 ar proliferations (GMP), accompanied by only modest endothelial cell death.

125 xternal forcings may have dwarfed the fairly modest ENSO response to precessional insolation changes

126 ans over the past 25 years, although we find modest evidence of a decline in discrimination against L

127 These results provide modest evidence of interaction between nutrition and NO2

128 tween PTSD and schizophrenia along with more modest evidence of overlap with bipolar and major depres

129 le coronary heart disease (CHD) are based on modest evidence.

130 ate, the benefits of immunotherapy have been modest, except in neoantigen-laden mismatch repair-defic

131 he other hand, bringing everybody to a still modest expenditure level of at least $2.97 PPP would hav

132 When the ferrofluid is subjected to a modest external magnetic field, the nanoparticles inside

133 IV acetaminophen thus produces modest fever reduction in critical care patients, along

134 Associations were weak or modest for physical inactivity, overweight or obesity, a

135 A modest fraction of the Tier 2 virus neutralizing activit

136 This highlights the role of modest free energy changes in the folding of pre-integra

137 d significant improvements in CD80, but only modest gains in CD86 binding.

138 of advanced-stage NSCLC occurred along with modest gains in survival and total Medicare spending.

139 tal insufficiency must be distinguished from modest genetic growth potential.

140 ased on OCTA area measurement: CNV doubling, modest growth of less than 50%, and shrinkage.

141 went CNV doubling, 19 eyes (46%) illustrated modest growth, and 6 (15%) showed shrinkage.

142 from the initial lead 4-phenylthiazole 18, a modest HCV inhibitor (EC50 = 9440 nM), a series of struc

143 anscriptional effects within these loci were modest, Hdac3(Delta/-) progenitor cells displayed global

144 Some of these analogues display modest herbicidal activities, and physiological profilin

145 Moreover, with only modest high-temperature tolerance despite high summer te

146 talytic site, the sequence of which had only modest homology among p38 isoforms.

147 Whether microbes also play a role in more modest host shifts or expansions in herbivorous insects

148 Given the modest humidity stability of the MOF, triaxial impedance

149 s for the possibility that Ceres experienced modest ice-rock fractionation, resulting in differences

150 emissive, and that derivatives of DIPYR have modest, if any, luminescence.

151 to produce microscale motion in response to modest illumination, with an actuation efficiency as hig

152 pression analysis revealed a significant but modest imbalance with rs10995 and rs10156, a single-nucl

153 aIV spectrin, followed by NaV channels, with modest impact on neurofascin 186.

154 nterventions reduced adiposity, and showed a modest improvement in glucose tolerance and improved mar

155 A modest improvement in overall survival was seen with exe

156 ined with antidepressant medication produces modest improvement in psychosocial outcomes.

157 CPAP was associated with modest improvement in sleep-related quality of life (Coh

158 d a statistically significant but clinically modest improvement on adolescent prediction of high cIMT

159 ith a QRSD 150 to 179 ms and LBBB had only a modest improvement.

160 nal manipulative therapy was associated with modest improvements in pain and function at up to 6 week

161 atment with bendamustine alone only achieves modest improvements in progression-free survival compare

162 density and airway inflammation and produced modest improvements in radiographic lung disease in subj

163 using HbA1c were more specific and provided modest improvements in risk discrimination for clinical

164 women, and minorities-its overall impact was modest in comparison with the gaps present before the la

165 arly changes that are recent, short-term, or modest in size.

166 ally, with the impaired dilator responses, a modest increase in adrenergic constriction combined with

167 pita PMI spending was also associated with a modest increase in artemisinin-based combination therapy

168 Cardiac pressure overload resulted in a modest increase in c-kit-derived cardiomyocytes, with si

169 A modest increase in comorbidity of ALS and schizophrenia

170 We determined the impact of a modest increase in dietary zinc that was similar to that

171 s have shown that exogenous FA causes only a modest increase in DNA adduct formation compared with th

172 buted to a complex phenotype consisting of a modest increase in fusion and cell killing, lower neuram

173 pathway or the mTor pathway but there was a modest increase in LC3-IIB, a marker of autophagosome bi

174 A modest increase in measured actinide:dipicolinate stabil

175 ompartments and, in a mouse model, exhibit a modest increase in pharmacokinetic bioavailability.

176 In adenine-induced uremia, only a modest increase in serum FGF23 levels occurred in mice w

177 ese drought conditions were accompanied by a modest increase in temperature (e.g., 1.5 degrees C), wa

178 We conclude that a modest increase in the content of 3-O-sulfo groups in BI

179 There was modest increase in the proportion of SDD after PCI from

180 mplitudes at low IVM concentrations, and the modest increase in the unitary conductance.

181 sis factor-alpha antagonist or placebo and a modest increase in vascular inflammation in carotids aft

182 The modest increased risk of diabetes associated with hyster

183 els following Opra Kappa administration, but modest increases in circulating adrenocorticotropic horm

184 Modest increases in concentration of C-reactive protein,

185 t sublethal effects, our model suggests that modest increases in developmental temperatures influence

186 ormula: see text]) whilst still allowing for modest increases in lattice parameter of up to a nanomet

187 ing women diagnosed after 2000 have observed modest increases in risk.

188 Hemodynamic measurements indicated modest increases in the right ventricular systolic press

189 age infectivities, from background levels to modest infection, with a small number of Envs from some

190 In contrast, Delta5G infection elicited only modest inflammatory responses.

191 compromised by variable sequence overlap and modest information content within each barcode.

192 ns SUN1/UNC84A and SUN2/UNC84B are potent or modest inhibitors of HIV-1 infection, respectively, and

193 effect not explained solely by foamy virus' modest insertional site preference for nongenic regions

194 Their ingestion induced modest intestinal myeloid cell infiltration and activati

195 e much smaller than unity even at relatively modest laser intensities, enabling the study of the stro

196 iction effects are important for polymers of modest length.

197 t in its circular dichroism spectrum under a modest level of excitation power.

198 that more closely resembled cDC, with only a modest level of L. monocytogenes replication.

199 It induces modest levels of protective efficacy, thought to be medi

200 f striatal dopaminergic terminal density and modest loss of SNpc dopamine neurons after eight weeks,

201 e results, we found each construct conferred modest MA currents in a small fraction of naive HEK cell

202 The proton energies we obtained were modest ( MeV), but prospects for improvement are offered

203 or high phosphofructokinase activity caused modest mitochondrial damage.

204 Air quality benefits of electrification are modest, mostly less than 1 ppb for ozone and 0.5 mug m(-

205 trate specificities, demonstrating that even modest mutants may not be suitable substitutes for the n

206 This effect provides a modest negative feedback on seawater composition and (87

207 D=1.1%) and 13.1% (SD=1.1%), respectively; a modest, negative correlation (r=-0.17; P=0.003) was foun

208 bottom-up ecological approaches indicating a modest net source.

209 s were more age-dependent, associated with a modest neutropenic effect (9%, P = .012), demonstrated f

210 A modest number of genes show evidence of specificity.

211 pe frequency differences, this study found a modest number of genomic differences but a significant c

212 ow with optically generated phonon fields of modest (nW) powers.

213 etic cause characterised by a few genes with modest or large effect size.

214 f newly identified peroxide stress genes had modest or no obvious consequences to bacterial survival,

215 ed drinking to social desirability bias, the modest participation rates of eligible patients, and the

216 ndividual sensitivity to TMS accounted for a modest percentage of the variance in the early after-eff

217 than 70 mg/dL in most patients, with only a modest percentage requiring a PCSK9 inhibitor.

218 mectin have a partial macrofilaricidal and a modest permanent sterilizing effect after 4 or more cons

219 Doxorubicin and trastuzumab resulted in modest, persistent declines in LVEF at 3 years.

220 xually selected traits often explains only a modest portion of the variation in mating success.

221 HBGM had modest positive effects on children with stunted growth.

222 increases stool weight and frequency and has modest positive effects on gut microbiota, SCFAs, effect

223 angiotensin system in heart failure has been modest, possibly because of the ability of renin-angiote

224 healthy body weights, BChE treated mice had modest postdieting food intake and showed normal glucose

225 he <2 % rate of anaphylaxis, fatal outcomes, modest predictive value of ST, resource requirements for

226 Our finding that p* can be tuned with a modest pressure opens a new route for experimental studi

227 measurements have been limited to relatively modest pressures (less than 100 gigapascals).

228 ribed testing levels represents a relatively modest proportion of existing budgets (<2%).

229 A possible modest protective association against atopy was observed

230 ively, but the correlation between the 2 was modest (r=0.53).

231 We observed modest rate increases for this reaction in the presence

232 neural integrity in IPD patients occurs at a modest rate over 2 y on (11)C-HED scans with marked hete

233 eeply upon recruitment but then level off at modest rates even though muscle force continues to incre

234 sperms, differing greatly from comparatively modest rates found in their closest living relatives.

235 urons increase steeply but then level out at modest rates.

236 as not well tolerated and resulted in only a modest reduction in anti-HLA antibodies.

237 wf(+/-) mice that are all characterized by a modest reduction in plasma VWF levels.

238 pproach are likely a reasonable tradeoff for modest reduction in sensitivity and inability to observe

239 he correction-factor approach yielded a more modest reduction in the estimated prevalence of iron-def

240 peats with pseudouridine (Psi) resulted in a modest reduction of MBNL1 binding.

241 Topical NSAIDs were associated with a modest reduction of PME incidence in patients undergoing

242 NIPA suppression results in a modest reduction of proliferation in vascular smooth mus

243 This stability and modest reduction potential of 0.99 V vs NHE is in part a

244 Modest reductions in burden will occur in the most pollu

245 accination during this time period, and more modest reductions in cervical cancer screening and sexua

246 ce PCV13 with reasonable coverage can expect modest reductions in hospitalised cases of pneumonia and

247 V-1) transcription in vivo but leads to only modest reductions in the size of the reservoir, possibly

248 free survival over the long term with only a modest relative increased risk of subsequent interventio

249 e unprocessed mitochondrial transcripts, and modest repression of mitochondrial translation in Drosop

250 an efflux pump cmeB mutation that conferred modest resistance.

251 y lipoprotein cholesterol (LDL-C) have shown modest results in identifying individuals with familial

252 One of the main features of this record is a modest rise in diversity over nearly a half-billion year

253 A modest rise in uric acid levels beginning early after do

254 Spouses of patients with AS only had a modest risk increase, suggesting that shared adult envir

255 realize near unit PhiISC at extraordinarily modest S1-T1 energy gaps ( approximately 0.25 eV).

256 S approach should be useful in research with modest sample sizes to investigate developmental, multiv

257 S) have produced mixed results, and most had modest sample sizes.

258 ith valproate and stiripentol, provides only modest seizure control.

259 otent binder to human AD aggregated tau with modest selectivity versus aggregated beta-amyloid (Abeta

260 yocardium, and the adult heart is capable of modest self-renewal.

261 ennae attached through triazole linkers were modest sensitizers for Eu(III) and Tb(III), whereas liga

262 reduction between POD1 and POD2 demonstrated modest separations in 12-month eGFR.

263 rates and prefers three or more but has only modest sequence preferences.

264 The DC-targeting vaccines also elicited modest serum Env-specific IgA responses.

265 to form an anisotropic hydrogel string under modest shear stress.

266 tion effects during media treatment and very modest shifts in pH values observed indicated sufficient

267 erminal residues have an additional but more modest significance for activity.

268 open Env trimers, and accumulate relatively modest somatic mutations.

269 The dentition shows only modest specialization for herbivory, consistent with its

270 t that urinary triclosan concentrations have modest stability over weeks to months; children are expo

271 es the on-rate of RecQ-DNA binding and has a modest stimulatory effect on the unwinding rate of RecQ.

272 ipoprotein particles, yet interrogate only a modest subset of pathways relevant to cardiovascular dis

273 use in cancer therapy, mTORis have met only modest success rates in clinical trials with advanced ma

274 y quaternary epitopes, which may explain the modest success with soluble recombinant E (sRecE) as a v

275 ion Quantitative Trait Loci (eQTLs) provides modest support for altered regulation of MLH1 and LRRFIP

276 infectivity, whereas the loss of SUN2 had a modest suppressive effect.

277 tectable level of UV-C (1.9 nWcm(-2)nm(-1)), modest surface temperature (60 degrees C with 60 s of ac

278 Conclusion We found a modest survival advantage with higher intake of protein,

279 on-small-cell lung cancer (NSCLC) provides a modest survival benefit.

280 ations for fruits and vegetables can provide modest system-wide water (4%) and land reductions (3%),

281 FBX had a modest systolic BP-lowering effect in T1D patients (112

282 es of 1/Tm for 1 and 2 up to about 160 K and modest temperature dependence up to 295 K, demonstrating

283 Thermal annealing at modest temperatures (e.g., 50-100 degrees C), and as low

284 e, but these changes were substantially more modest than in thymocytes lacking all Tcf1 isoforms.

285 simulations, we show that although currently modest, the impact of dichloromethane on ozone has incre

286 FST provides analgesia with modest to moderate increased risk of lower efficacy comp

287 Across cortical areas, modest transcriptional differences among radial glia cas

288 the TFs binding to OsNHX1 promoter showed a modest transcriptional regulation under stress condition

289 Only 2C10R4-treated animals exhibited a modest, transient drop in CD20 lymphocytes from baseline

290 dministration was safe and associated with a modest treatment response after 52 weeks, with the highe

291 iation studies, the results have been fairly modest, underlining the need to establish conceptually n

292 However, we have a surprisingly modest understanding of the organization of value across

293 igh-leverage outliers and in some cases only modest variation in probability, but these issues do not

294 demonstrated significant perturbation due to modest warming (+2 degrees C), altering the magnitude an

295 tyle treatment alone typically produces only modest weight loss that is difficult to sustain.

296 tigated, the absorbed doses were found to be modest when compared with commonly assumed tolerance lim

297 econfigurations of task-related networks are modest when compared with intrinsic "resting-state" netw

298 biological systems use an entatic state for modest yet accessible energetics to modulate chemical fu

299 rPfs25 was purified with a modest yield but required the incorporation of refolding

300 The deficits in cognitive performance were modest (Z score reductions between 0.01 and 0.51), compa