ライフサイエンスコーパス: modulate

1 ut methyltransferases themselves may also be modulated.

2 the plasticity of meiosis and how it can be modulated.

3 , thereby suggesting a potential approach of modulating Abeta levels and attenuating synaptic deficit

4 r CML36 as a Ca(2+) sensor that binds to and modulates ACA8, uncovering a possible involvement of the

5 during UV and oxidative stress may serve to modulate active DNA repair.

6 ferent neurons in upstream brain regions may modulate activity in the target brain region during tDCS

7 that anti-TNF-alpha therapy or RA itself can modulate AD pathology, although the underlying mechanism

8 s that pro-inflammatory markers can directly modulate affective behavior.

9 Exogenous T on its own did not modulate aggressive behavior.

10 ta2AR reveals the mechanism by which Cmpd-15 modulates agonist binding affinity and signalling.

11 suggesting a positive role of linagliptin in modulating alpha cell function to restore normoglycemia.

12 as assessed in response to different stimuli modulating amino acid catabolism, as were cytokine secre

13 the AD brain, TNF-alpha can also indirectly modulate amyloid pathology as a regulator of peripheral

14 n of the UPR enforces adaptive programs that modulate and augment key aspects of the entire secretory

15 We hypothesized that VLDL can modulate and reduce atrial gap junctions.

16 The network utilized both reward modulated and non-reward modulated STDP and implemented

17 In this highly modulated and oscillating circuit, neuronal structures a

18 nd aerosols are important factors governing, modulating, and even reversing the expected urban-rural

19 croRNA93 (miR93) has been shown to favorably modulate angiogenesis and to reduce tissue loss in genet

20 ating AIBP as a possible druggable target to modulate angiogenesis under pathological conditions.

21 nd clustered, limiting access to aggregation-modulating antibodies.

22 creased activation of NMDA receptors in pain-modulating areas.

23 p), which signals to the actin cytoskeleton, modulates autophagy and inflammasome function.

24 unveils a noncanonical function of ErbB2 in modulating autophagy and establishes ErbB2 as a therapeu

25 sal states puts the PPN in a key position to modulate behavior.

26 ey role in mediating the effect of leptin to modulate beta-cell electrical activity by promoting AMP-

27 hether the phosphorus cycle has consistently modulated biospheric productivity and ocean-atmosphere o

28 l-known regulatory roles that SIRT1 plays in modulating both anabolic and catabolic pathways, allow u

29 that top-down beta-band influences directly modulate bottom-up gamma band influences via cross-frequ

30 ing DNA damage response factor, ZMYM3, which modulates BRCA1 functions within chromatin to ensure the

31 By modulating Brevican levels, experience introduces precis

32 known whether responses to spatial cues are modulated by active spatial listening.

33 ctivity and acquisition of resistance can be modulated by administration of pro- and antiquorum-sensi

34 In conclusion, LAT1 is modulated by cholesterol impacting on its stability and

35 Fifty-seven miRNAs were detected as modulated by cytokines.

36 nal predicted performance beyond age and was modulated by D1 availability in nucleus accumbens.

37 Here we report the key autophagy regulators modulated by diabetes in the murine developing neuroepit

38 However, GLI1 expression was modulated by either inhibition or activation of the PI3K

39 the C. neoformans-macrophage interaction is modulated by exogenous lipids, providing a new tool for

40 -dimensional (2D) MoS2 semiconductors can be modulated by introducing specific defects.

41 IFN mediated innate immune response that is modulated by IRF7 and IRF1.

42 a metabolic enzyme and whose activity can be modulated by metabolic cues.

43 arsenite, As(III) vs. arsenate As(V)) can be modulated by microbes.

44 nd responds to stress; such responses may be modulated by MisRS (NGO0177 and NGO0176), a two-componen

45 chromosome dynamics and gene expression are modulated by nucleoid-associated proteins (NAPs), but li

46 osteoblasts reduced appetite, a function not modulated by OCN, thus suggesting that osteoblasts may s

47 we show that the phosphoinositide signaling modulated by phosphatidylinositol transfer protein type

48 ortantly, whisker response amplitude is also modulated by presentation of a movie recreating the mous

49 , which are coupled to ECM signaling that is modulated by protrusion/contraction.

50 ithin the P2X7R C-terminus is differentially modulated by repeated morphine treatment and has no bear

51 Competitive interactions can be modulated by resource availability and we hypothesized t

52 timulus in a neuron's receptive field can be modulated by stimulus context, and the strength of these

53 sitive C fluxes-climate warming feedback was modulated by the changing N and rainfall regimes.

54 ion of the tumor suppressor gene PTEN can be modulated by the expression of other miRNA targets actin

55 se (PNPase), has previously been shown to be modulated by the Krebs cycle metabolite citrate in Esche

56 ed potential association of select claudins, modulated by the obesity, with signaling and metabolic p

57 In particular, gamma activity was modulated by the phase of the alpha oscillations.

58 channel, spike output functions are strongly modulated by the prestimulus membrane potential.

59 or and its intracellular localization can be modulated by ultraviolet light, suggesting a potential r

60 The electron branch is modulated by varying the BV dopant concentrations and an

61 ht-induced electron transfer can be strongly modulated by vibrational excitation, suggesting a new av

62 red by interaction with the microenvironment modulate cancer cell phenotypes and properties, and shap

63 umor microenvironment has been implicated in modulating cancer cell migration and independently predi

64 the complexity of the processes involved in modulating carotenoid homeostasis in plant tissues.

65 the latter compounds are highly effective in modulating CE activity.

66 isk, and narrow intercellular separation can modulate cell-to-cell coupling via extracellular electri

67 y expressed in neurons and muscle where they modulate cellular activity.

68 tect and deliver active mediators to locally modulate cellular function during inflammation.

69 To investigate whether the intradisulfide modulates cGMP binding, real-time imaging was performed

70 It also indicates that the lipid bilayer modulates channel gating, although it is not clear how.

71 Spt4 as a factor that appears to negatively modulate Chd1 binding to chromatin.

72 sm is an expression quantitative trait locus modulating CHRNA4 expression levels.

73 the paracellular Ca(2+) transport pathway by modulating Cldn14 expression in the TAL.

74 sts that target sequence and chromatin state modulate cleavage and repair kinetics.

75 Accordingly, NPY was shown to modulate cognitive functions in rodents.

76 train endogenous brain oscillations, thereby modulating cognitive processes supported by those brain

77 de (NO) are known, the mechanism by which NO modulates corneal wound healing remains unclear.

78 r the ventral striatum, given its ability to modulate cortical information flow, contributes to consc

79 sinusoidal, subthreshold, electric fields to modulate cortical processing.

80 We hypothesized that MUC4 modulates corticosteroid efficacy of patients with CRSwN

81 Value furthermore modulated coupling between prefrontal areas, brainstem,

82 Initially identified for their role in modulating CREB transcription, the past 5 years has seen

83 al similarity of cross-modal signals may not modulate cross-modal temporal influences in short time s

84 ure and the low-temperature incommensurately modulated crystal structure (for Sm2Ru3Ge5 as a represen

85 EN directly regulates oncogene expression by modulating DAXX-H3.3 association on the chromatin, indep

86 The modulated density of states generates a higher transcond

87 niche in many organs, and thereby pivotally modulates development, homeostasis, and plasticity.

88 subunit, BAF60, represses seedling growth by modulating DNA accessibility of hypocotyl cell size regu

89 Results showed that tumor progression modulated drug vector distribution in tumor-associated c

90 immune system, and evidence suggests that it modulates drug-related behavior.

91 ognitive representations, such as value, can modulate early pain processing.

92 addition, primary cilia seem to functionally modulate effects of EFS-induced cellular calcium oscilla

93 ted to inhibit the secretion of cytokines by modulating either CXCR4 or CXCR4-mediated signaling.

94 d that there is a key role for motivation in modulating empathic experiences.

95 he Toll-like receptor 9 (TLR9) ligand CpG to modulate established disease in the L (V) panamensis mou

96 ver the estrous/menstrual cycle, dynamically modulating estrogen receptor (ER) expression, activity,

97 ransient species for experiments obeying the modulated excitation paradigm and exploiting phase sensi

98 Desmoglein 2 modulates extracellular vesicle release from squamous ce

99 ional mechanism by which GABABRs are able to modulate fast synaptic inhibition.

100 hormones but also to FA nutrient signals to modulate food-directed behavior.

101 Side mode suppression is electrically modulated from 6 dB to 21 dB, demonstrating active, op

102 g the role of multiple regulatory factors in modulating Fshb gene activity.

103 of factors in addition to TCR sequence that modulate functionality and contribute to the increased a

104 In conclusion, MetS-VLDL modulates gap junctions and delays both atrial and ventr

105 rvation that the ability of dexamethasone to modulate gene expression in airway epithelial cells coin

106 ed class of regulatory RNAs in bacteria that modulate gene expression via small-molecule-induced conf

107 counteracting oxidative promoter lesions may modulate gene expression.

108 cRNAs) are recognized as important actors in modulating gene expression, and this study demonstrates

109 response to various environmental stress by modulating gene expression.

110 resentative ethylene-responsive and ripening-modulated genes confirmed and validated sHSP transcript

111 However, L/Zi supplementation modulates genes involved oxidative stress and inflammati

112 For hydration water to play a role beyond modulating global protein solubility or stability, the t

113 nvironment in the intestine and to partially modulate glucose metabolism.

114 chemically, and functionally diverse ligands modulate GPCR function.

115 targeting of their interaction interfaces to modulate GPCR functions selectively have not been fully

116 suggest that Gbeta1 protein enlists PP1c to modulate GPCR signaling in platelets.

117 known that protein kinases and phosphatases modulate GPCR signaling, how serine/threonine phosphatas

118 putative role for the vaginal microbiome in modulating heterosexual transmission of HIV, uncovering

119 ion, and reveals a potential drug target for modulating Hh signaling activity.

120 echanisms by which hepcidin and hypoferremia modulate host defense, and the spectrum of microbes affe

121 on cell metabolism, HO-1 is also capable of modulating host innate and adaptive immune responses in

122 different membrane proteins are combined to modulate how strongly sensory neurons respond to mechani

123 Our findings suggest that PP1 modulates HTTex1 aggregation by regulating phosphorylati

124 f transcranial direct current stimulation to modulate human neuroplasticity have increased in researc

125 m distinct mechano-sensors are integrated to modulate hypertrophy and gene expression in cardiomyocyt

126 NF influences food intake and body weight by modulating hypothalamic insulin signaling.MANF is a neur

127 e antimicrobial protein calprotectin without modulating IL-17 expression.

128 MHC-I-specific inhibitory receptors, and is modulated in an education-dependent fashion.

129 as previously shown histone deacetylases are modulated in cells derived from alcohol users and after

130 as affected by CNOT3 loss, and also at sites modulated in certain types of colorectal cancers.

131 red vacancies of the same Ce atoms that were modulated in the first domain type, leading to sum formu

132 IL-18 activity is modulated in vivo by its naturally occurring antagonist,

133 Mechanistically, global knockout of PLD4 modulated innate and adaptive immune responses and atten

134 gamma2 in osteoclast (OC) differentiation by modulating inositol 1,4,5-trisphosphate-mediated calcium

135 Using a ternary mixture of lipids, the modulated-intensity profile of elastic back-scattered li

136 anisms by which gap junction nexus stability modulates intercellular communication.

137 diac physiological adaptation to exercise by modulating intrinsic sinoatrial cell behavior.

138 ied through the resonator to induce heat and modulate its stiffness, and hence its resonance frequenc

139 erial pathogen responsible for Lyme disease, modulates its gene expression profile in response to the

140 uggest that PON-2 regulates ENaC activity by modulating its intracellular trafficking and surface exp

141 reducing prion pathogenesis, suggesting that modulating its levels/activity may offer a novel opportu

142 he narrowband gamma oscillation, the factors modulating its strength, and its relationship to broadba

143 n and thus may be among the early mechanisms modulating later susceptibility to diabetes.

144 , suggesting that CircPVT1 might selectively modulate let-7 activity and hence expression of let-7-re

145 fic Runx1-bound enhancer elements critically modulate lineage-dependent expressions of PLZF.

146 ioxidant methionine sulfoxide reductase A to modulate liposarcoma cell survival and ASC differentiati

147 Genital immune activation is suspected to modulate local human immunodeficiency virus (HIV) RNA le

148 s compared with TsSPs and commercial PGE2 in modulating LPS-induced expression of many cytokines and

149 component in DC homeostasis, is required to modulate lung inflammation and bacterial burden in TB.

150 acental vitamin D metabolism and its role in modulating maternal circulating vitamin D metabolites du

151 orts Ca(2+) into the mitochondrial matrix to modulate metabolism.

152 scuss the origin and influence of microbiome-modulated metabolites, with an emphasis on immune cell d

153 Paxillin, by modulating microtubule acetylation through HDAC6 regulat

154 gulator of multiple ARGs that have a role in modulating motivation for cocaine.

155 brain stimulation (DBS) within circuits that modulate motor function.

156 , TSP-1 appears to play an accessory role in modulating Mp activity in BlaJ mice in a gender, age and

157 ed modification N(6)-methyladenosine (m(6)A) modulates mRNA processing and activity.

158 -6 receptor [IL-6R]) which holds promise for modulating multiple immune pathways responsible for allo

159 he exact chemical mechanisms responsible for modulating myocardial mPTP opening remain unclear.

160 ding of how organic carbon and nitrite loads modulate N2O accumulation in denitrification, which may

161 terface containing] by which prototoxins can modulate nAChR function.

162 lue light and release paracrine factors that modulate nearby cells.

163 asally administered oxytocin and vasopressin modulated neural activity when receiving negative feedba

164 ttle efficacy, indicating limited success in modulating neuroplasticity, especially in brains with ne

165 BBB and offers potential clinical targets to modulate neuroprotection and drug delivery to the CNS.

166 methods reveal that conformational switches modulate normal and abnormal information transfer and th

167 The aberrant CCSC compartment observed after modulating O-GlcNAc levels is therefore likely to result

168 To investigate how reward history modulates OFC activity, we recorded OFC ensembles as rat

169 show that the neuromodulator norepinephrine modulates olfactory bulb spontaneous activity and odor r

170 CtBP modulates oncogenic gene expression programs and is an e

171 their proliferation and, at a late stage, by modulating OPC maturation.

172 in a uniaxial dielectric with a transversely modulated orientation of the optic axis.

173 rted recently that NUMB-like (NUMBL) protein modulates osteoclastogenesis by down regulating NF-kappa

174 l-induced regularity in vegetation-which can modulate other patterning processes in functionally impo

175 ravasation and diffusive transport as key RF-modulated parameters, with transport being dominant.

176 gesting an ATGL-independent role of ABHD5 in modulating PCa aggressiveness.

177 Last, we show that some SNPs allosterically modulate PCSK9's substrate sequence specificity.

178 n vivo, we show that GBA-dependent signaling modulates phenotypes during Xenopus laevis embryonic dev

179 ved in the formation of circRNAs and further modulate phenotypic variation.

180 Additionally, while these substitutions modulate PON1's active site shape, volume, and loop flex

181 ecting overall potassium balance and factors modulating potassium dialysate fluxes in dialysis, and w

182 t U2AF1 and utilize sudemycin compounds that modulate pre-mRNA splicing.

183 amic changes in transitional metal pools can modulate protein function, cell fate, and organism healt

184 potential of this thermodynamic variable to modulate protein-ligand interactions.

185 cytosolic poly(A)-binding protein 1 (PABPC1) modulates protein synthetic capacity of the mammalian he

186 Modulating protein turnover in ATM-depleted cells also h

187 binding amyloid beta precursor proteins and modulating PS1 catalytic activity.

188 sion of many cytokines and chemokines and in modulating Rab7B and P2RX7 expression in human DCs.

189 t FER acts as a RALF-regulated scaffold that modulates receptor kinase complex assembly.

190 system provides extrinsic neural inputs that modulate, regulate, and integrate these functions.

191 Because the number of molecules modulating RGGT is limited, we combined molecular modeli

192 Specific codons and codon combinations modulate ribosome speed and facilitate protein folding.

193 eering immune cells, and constructing immune-modulating scaffolds.

194 and reveal distinct requirement for RFOs in modulating seed vigor in a monocot and a dicot.

195 g represent the first achiral molecules that modulate selectively hUII and URP biological activities.

196 is for the O1 --> O2 transition and how ChR2 modulates selectivity between states is currently unreso

197 oneybees, it is assumed to have functions in modulating sensory responsiveness and controlling motor

198 l proteins able to simultaneously coordinate/modulate several cellular pathways is unclear.

199 indicates that dopamine neurons selectively modulate signal reception processed by afferent nuclei.

200 Surprisingly, these synthetic ligands modulated signaling of a GPR56 mutant defective in autop

201 Scaffold proteins modulate signalling pathway activity spatially and tempo

202 By dynamically modulating signals from the contrast agents with an exte

203 task, although a subset of the responses is modulated similarly to prefrontal and parietal cortex.

204 vity in the hypothalamus and medial amygdala modulates social interactions.

205 the semiconducting conduction pathway to be modulated solely by surface functional groups in a chemi

206 to the well-described paracellular route to modulate solute transport from the interstitium accordin

207 The ability to generate, amplify, mix and modulate sound in one simple electronic device would ope

208 endothelial angiogenesis and tumor growth by modulating Sp1-mediated VEGF expression.

209 rations in gene expression are well known to modulate spermatogenesis, posttranscriptional mechanisms

210 receptor 4 (TLR4) through its N terminal and modulates STAT3 and TBK1 signaling, triggering a switch

211 tilized both reward modulated and non-reward modulated STDP and implemented multiple mechanisms for h

212 t liver repair and to block tumorigenesis by modulating stem-like cells and beta-Cat signaling.

213 e new insights into how chromatin regulation modulates stochastic gene expression and transcriptional

214 k for persistent asthma, potentially through modulating susceptibility to early allergic sensitizatio

215 , these data indicate that neuron-derived E2 modulates synaptic plasticity in rodent BLA sex-dependen

216 responses (i.e., satisfaction ratings) were modulated systematically by the attraction effect and th

217 blue, a reported tau aggregation inhibitor, modulates tau acetylation, a novel mechanism of action f

218 ave uncovered an lncRNA-based mechanism that modulates TGF-beta/Smad3 signaling during SMC differenti

219 e the mechanisms by which noninflammatory SF modulate Th cell responses and to determine the immunosu

220 engineer antibody fragments (Fabs) that can modulate the activity of the enzyme isocitrate dehydroge

221 lular signals associated with integrins that modulate the autophagy response and dictate the balance

222 ere introduced in the conjugated backbone to modulate the band gap.

223 lational modification of histones, serves to modulate the chromatin environment.

224 tonic current by ethanol suggests that they modulate the excitability of DRD1-positive MSNs in nAc.

225 iform layer, where inhibitory amacrine cells modulate the excitatory signal of bipolar and ganglion c

226 y of lamin and nesprin-1 is thus required to modulate the FHOD1 activity and the inside-out mechanica

227 surface chemistry is a key consideration to modulate the formation of the serum protein corona (PC)

228 particular, SRp55-mediated splicing changes modulate the function of the proapoptotic proteins BIM a

229 ilitate the specific binding of proteins and modulate the global folding and interactions of double h

230 Different factors may modulate the gut microbiota of animals.

231 he results suggest that V. fischeri may help modulate the host stress responses under modeled microgr

232 ersely, stem cells are also able to directly modulate the immune response through the production of i

233 re, stress fibres and intermediate filaments modulate the mechanical properties of the nucleus and al

234 lar organization and mobility, and spatially modulate the membrane's properties on a length scale of

235 that patient, donor, and transplant factors modulate the phenotype.

236 tudies have shown that CME proteins actively modulate the plasma membrane curvature.

237 lthough channelrhodopsins are widely used to modulate the plasma membrane potential of excitable cell

238 the arrangements of nucleosomes in chromatin modulate the properties of longer polymers.

239 ghlight that transcriptional enhancers might modulate the release of paused RNAPII via 3D chromatin l

240 unty-level corn spatial distribution pattern modulate the response of its yields to climate change at

241 n S1s and intracortical inhibition in the S1 modulated the amplitude of the P25/N33.

242 Interestingly, TKIs modulated the chemokine receptor repertoire of immune ce

243 Vulnerability modulated the expression of prediction error responses i

244 -related signal in the amygdala (P=0.01) and modulated the food-related signal in the medial orbitofr

245 Task relevance modulated the influence of predictions on behaviour: spa

246 t that was embedded in a rapid visual stream modulated the perception of a subsequent near-threshold

247 Our results indicate that DnaA modulates the activity of Rok.

248 Locomotion modulates the activity of the SC cells both additively a

249 lucocorticoid signaling in chondrocytes also modulates the course and severity of arthritis.

250 he authors show that a secreted neuropeptide modulates the distribution of bacterial communities on t

251 d trait and a plasticity modifier locus that modulates the effects of target-locus alleles.

252 rostimulation in the prefrontal cortex (PFC) modulates the gain of the PLR, changing how a simple ref

253 ed cells and liver biopsies to study how HCV modulates the glutaminolysis pathway, which is known to

254 te for partner proteins and we report how it modulates the interaction of the regulator protein TubY.

255 A growing literature shows that body posture modulates the perception of touch, as well as somatosens

256 r, it is unclear whether ligand density only modulates the proportions of responding ligand-specific

257 l role for PRDM15 as a chromatin factor that modulates the transcription of upstream regulators of WN

258 keup and microenvironment, which dynamically modulates the tumor landscape.

259 flowing Kuroshio often intrudes westward and modulates the water masses of the South and East China S

260 by targeting slit-1 mRNA or, potentially, by modulating the canonical Notch pathway.

261 elength, lambda0, which can be controlled by modulating the carrier density of graphene via electrica

262 dback control on T-type channel activity, by modulating the channel availability, a mechanism that cr

263 g that CCR2 regulates the immune response by modulating the effector/regulatory T ratio.

264 at these miRs regulate leukocyte adhesion by modulating the expression of adhesion-associated endothe

265 Most importantly, when modulating the expression of hDBR1, which was found to b

266 results will spark renewed investigation in modulating the function of these cells and developing no

267 ates the rotation of the lectin domain, thus modulating the GalNAc-Ts' long-range preferences.

268 om HCV-infected hepatocytes activates HSC by modulating the SOCS-STAT3 axis.

269 e size can be precisely controlled by simply modulating the starting peptide and fluorinated solvent

270 roximately 75% of light-responsive SCN units modulate their firing according to simple spatial patter

271 Only recently were bacteria shown to modulate their membrane potential on the timescale of se

272 the structural context in which PAINS occur modulates their effects.

273 eimer's disease amyloid-beta (Abeta) peptide modulates their self-assembly into amyloid fibrils and m

274 stigate how a different protein scaffold can modulate these energies, we measured DeltaDeltaGsc(o) fo

275 D pathogenesis and additional strategies for modulating these pathways.

276 ions can be rapidly up- or down-regulated by modulating theta phase coupling of distant frontal corti

277 ations at predicted channel-facing positions modulate this effect.

278 Ring size and adjacent steric hindrance modulate this hidden hydrophilicity, thus making this sc

279 ir activation under different conditions can modulate this process.

280 we investigated the role of exogenous ABA in modulating thrombopoiesis, the process of platelet gener

281 on of these mRNAs and proteins, which can be modulated through posttranscriptional regulation.

282 In conclusion, IFC selectively modulates tissue characteristics and thereby attenuates

283 reactive oxygen species (ROS) production and modulate TLR responses, but whether these enzymes functi

284 ncoded enzymes (histone deacetylases) can be modulated to alter acetylation of nonhistone proteins du

285 onducting polymer microcups can be precisely modulated to control electrical properties and drug-load

286 s work provides information to intelligently modulate tomato sauce attributes and tailor its properti

287 s applied locally to the skin can be used to modulate touch and may represent peripherally available

288 overs a potential new way for transposons to modulate transcriptomic and phenotypic variations.

289 show that editing alters gene expression by modulating translation (but not RNA stability or localiz

290 , autophagy has been shown to be involved in modulating tumor cell motility and invasion, cancer stem

291 monstrated a stiffness-driven, retinoic-acid-modulated upregulation of SIRPalpha and the mechanosensi

292 onstrate a novel mechanism by which laminins modulate vascular branching and endothelial cell prolife

293 HER2 trastuzumab moiety paired with affinity-modulated VH and VL regions of the anti-EGFR GA201 mAb w

294 However, how living cell functions can be modulated via opsins by modifying fundamental nonlinear

295 hydroxylase-immunopositive cells (TH cells) modulate visually driven signals as they flow through re

296 ion of these toxic tau species, which can be modulated with Hsp90 inhibitors.

297 opy shows that doping level can be optically modulated with similar resolution.

298 Apcdd1 thus serves to precisely modulate Wnt/Norrin signaling activity in the retinal en

299 the Wnt inhibitory function of Wise and also modulates Wnt/beta-catenin signaling independently of Wi

300 the molecular mechanisms of Lrp4 function in modulating Wnt signaling, we performed an array of genet