ライフサイエンスコーパス: modulating protein

1 alovirus-encoded viral interleukin-10 immune-modulating protein.

2 many cellular constituents, including actin-modulating proteins.

3 These results implicate a role for CypD in modulating protein acetylation.

4 executes a specific strategy targeting actin-modulating proteins, across multiple functionalities, to

5 nd enhancing the activity of the small actin modulating protein, actin depolymerising factor (ADF) in

6 y numerous roles in cell function, including modulating protein activity by changing protein conforma

7 e limited or extended complementarity, or by modulating protein activity, in some cases by mimicking

8 tion, and cell homeostasis are maintained by modulating protein and lipid flux through the early secr

9 ategories over-represented with MMS-toxicity modulating proteins and demonstrate that, in addition to

10 at YopO phosphorylates a wide range of actin-modulating proteins and located their phosphorylation si

11 ese results support a model in which F-actin modulating proteins and vesicle trafficking proteins coo

12 entified seven highly connected MMS-toxicity modulating proteins associated with translation and mRNA

13 role in cellular signaling, most notably by modulating proteins bound at chromatin and increasingly

14 utative Ku helicase activity plays a role in modulating protein conformation under the conditions tes

15 nkeys may alter insulin signaling in vivo by modulating protein content of insulin receptor signaling

16 The apoptosis-modulating protein Daxx functions as a transcriptional r

17 We find that modulating protein diffusion with flow, or membrane bind

18 ium may serve as a key regulatory switch for modulating protein-DNA interactions central to nuclear r

19 Importantly, modulating protein-DNA interactions of the fork-proximal

20 Arg49 in Tdx, His49 in Pdx, His56 in Adx) in modulating protein dynamics as a function of oxidation s

21 ted fatty acids regulate lipid metabolism by modulating protein expression at many levels including g

22 n of translation is the primary mechanism of modulating protein expression during mitosis.

23 ript splicing for the purpose of rescuing or modulating protein expression.

24 in1 regulates multiple signaling cascades by modulating protein folding and thereby activity and stab

25 lass of molecular chaperones responsible for modulating protein folding in the cell.

26 it to compare 303, 311 and 288 UVC-toxicity modulating proteins from Escherichia coli, Schizosacchar

27 up of lysine provides an additional means of modulating protein function and, in particular, enzyme a

28 methyltransferases plays essential roles in modulating protein function in both normal and disease s

29 biquitin conjugation is an essential process modulating protein function in eukaryotic cells.

30 lationship between O-GlcNAc and phosphate in modulating protein function in many cellular processes a

31 tions regulate physiology either by directly modulating protein function or by impacting immune recog

32 also for understanding the role of lipids in modulating protein function or drug binding.

33 an attractive but underexplored approach to modulating protein function with small molecules.

34 other homo-oligomeric proteins as a means of modulating protein function.

35 rted motions suggesting anesthetic action in modulating protein function.

36 or tyrosine (D187Y) in domain 2 of the actin-modulating protein gelsolin causes the neurodegenerative

37 We show that toxicity-modulating proteins have similar topological properties

38 old to Escherichia coli hemolysin expression modulating protein Hha; however, structural differences

39 n during differentiation is downregulated by modulating protein interaction at the site II cell cycle

40 not identified, Ran is known to function by modulating protein interactions for karyopherin (Kap) be

41 y can be tuned between these two pathways by modulating protein interactions.

42 s, and identify a nontransgenic strategy for modulating protein levels in crop species, a trait of gr

43 re limited for specific applications such as modulating protein levels or specific targeting of a pos

44 , may play previously unappreciated roles in modulating protein levels via ubiquitination.

45 the dynamics of S-thiolation and its role in modulating protein nanomechanics, offering molecular ins

46 We have also mapped our MMS-toxicity modulating proteins onto an E. coli protein interactome

47 n a pluripotent state by posttranslationally modulating protein PARylation.

48 Camstatin, an analogue of the calcium-modulating protein Pep-19 strongly expressed in CA2 neur

49 unctions as a master regulator of mitosis by modulating protein phosphatase 1 (PP1).

50 rylation (P < 0.05) of the Na(+),K(+)-ATPase modulating protein phospholemman at serine residue 63 (S

51 Gelsolin is a key actin cytoskeleton-modulating protein primarily regulated by calcium and ph

52 2 enhance shuttling of SRSF5 in P19 cells by modulating protein-protein and protein-RNA interactions.

53 ic function, at least in part, by positively modulating protein-protein interaction between Cdc42 and

54 ing that it is more likely to be involved in modulating protein-protein interaction than in interacti

55 Methionines can play an important role in modulating protein-protein interactions associated with

56 the biogenesis of secreted agouti protein or modulating protein-protein interactions that contribute

57 However, disrupting or modulating protein-protein interactions with low-molecul

58 These observations suggest that, by modulating protein-protein interactions within homo- and

59 is known about the role that lipids play in modulating protein-protein interactions.

60 and BRCA1, are attractive targets for drugs modulating protein-protein interactions.

61 ut also for the discovery of small molecules modulating protein-protein interactions.

62 ment and optimization of pharmaceuticals for modulating protein-protein interactions.

63 ly rigid, membrane permeable, and capable of modulating protein-protein interactions.

64 and the GA offers unexpected mechanisms for modulating protein secretion and/or endosome recycling e

65 tructures, they are unexpectedly involved in modulating protein secretion.

66 ight the roles of lipids, membrane curvature-modulating proteins, small G proteins, actin, and dynami

67 e residues play essential roles in proteins, modulating protein stability, fold and function.

68 rves as the key regulator of p53 function by modulating protein stability.

69 scriptional activator, and yhbH, a sigma(54) modulating protein, suggests sigma(54) may be involved i

70 ) pathway is known to play a central role in modulating protein synthesis and autophagy.

71 uggesting that RIP blocks ischemic injury by modulating protein synthesis and nerve activity.

72 evolutionarily conserved function of Myc in modulating protein synthesis control is critical to the

73 w role for PTalpha as a coregulator activity-modulating protein that confers receptor specificity.

74 Exciting new work on autophagy-modulating proteins that are enriched at the synapse has

75 ondrial K7 protein targets a cellular Ca(2+)-modulating protein to confer resistance to apoptosis, wh

76 se study was developed to identify compounds modulating protein translation directed from the interna

77 Modulating protein turnover in ATM-depleted cells also h

78 Seeking novel PKR-modulating proteins we report here that nucleophosmin (N

79 tion to the nucleus, subnetworks of toxicity-modulating proteins were overrepresented in the vacuolar

80 ter immunizations, suggesting that these APC-modulating proteins, when used as poxvirus-encoded adjuv

81 The actin-modulating protein Wiskott-Aldrich syndrome protein verp

82 gh-resolution solution structure of Yersinia modulating protein YmoA is presented.