ライフサイエンスコーパス: molecular crowding

1 the cellulose-pectin contacts are not due to molecular crowding.

2 ed, indicating that CCVs sort their cargo by molecular crowding.

3 oss the cell cytoplasm is slowed down due to molecular crowding.

4 also promoted by high osmotic potentials or molecular crowding.

5 ffects on macromolecular assembly processes: molecular crowding.

6 cules can fine-tune gene circuit response to molecular crowding.

7 used model system for studying intracellular molecular crowding.

8 complexes with other sticky proteins due to molecular crowding.

9 eractions that are effectively equivalent to molecular crowding.

10 essive on artificial actin bundles formed by molecular crowding.

11 tracting muscle than in vitro because of the molecular crowding.

12 ation by ATP is facilitated by conditions of molecular crowding.

13 y of DNAs >250 bp in cytoplasm is because of molecular crowding.

14 residues in the ER enhances even further the molecular crowding, accelerating protein denaturation.

15 This article shows that molecular crowding affects differently the transit of va

16 how perturbed ionic balance, in addition to molecular crowding, affects membrane trafficking.

17 ted sample of ubiquitin in the commonly used molecular crowding agent bovine serum albumin.

18 nded DNA template in the presence of a macro-molecular crowding agent, and that this coupled "two-pro

19 presence of polyethylene glycol, added as a molecular crowding agent.

20 turants, salts, viscosity enhancers or macro-molecular crowding agents has an impact on the physical

21 However, the effect that molecular crowding agents have on the folding and cataly

22 cleavage assays to determine the effect of a molecular crowding agents on the folding and catalysis o

23 ar that they can be independently altered by molecular crowding agents or via external fields.

24 lar sandwiched structures in the presence of molecular crowding agents.

25 ctures normally seen only in the presence of molecular crowding agents.

26 environment effects in RNA folding, such as molecular crowding and cotranscriptional kinetic effects

27 To explore the effects of molecular crowding and excluded volume upon protein stab

28 terial in which the effects of biochemistry, molecular crowding and physical forces are complex and i

29 used to address the effect of intracellular molecular crowding and related hydration on a model telo

30 ory of glass formation based on the ideas of molecular crowding and resultant string-like cooperative

31 In this work, the effects of molecular crowding and several physiologically important

32 ns for this behavior are: immobile barriers, molecular crowding, and binding interactions with immobi

33 he vectorial nature and rate of translation, molecular crowding, and cellular biosynthetic machinery.

34 the solubility of sickle hemoglobin, due to molecular crowding, and provides a useful ranking tool f

35 The effects of CA concentration, molecular crowding, and the conformational variability o

36 nce of polyethylene glycol to rule out inert molecular crowding as the driving force for the protein

37 itory effect is the predicted consequence of molecular crowding by high concentrations of unrelated s

38 ts of thermodynamic nonideality arising from molecular crowding by trimethylamine N-oxide on the self

39 present model for polymerization, including molecular crowding, can accurately predict the rates of

40 Here, we report that molecular crowding comparable to that in the cell compen

41 Furthermore, by manipulation of molecular crowding conditions (entropic forces), we were

42 We determined that molecular crowding conditions and cations, such as Na(+)

43 gher than 37 degrees C, especially under the molecular crowding conditions and in the presence of K(+

44 ges occurring under physiologically relevant molecular crowding conditions in ultrathin biosensor lay

45 ion osmotic pressure, thus mimicking in vivo molecular crowding conditions.

46 edominant form of the holoenzyme, even under molecular crowding conditions.

47 delay suggests that, although volume-induced molecular crowding contributes to trafficking defects, i

48 ikely more relevant to natural systems since molecular crowding events in the cytosol can influence t

49 NMR structures solved under molecular crowding experiments correlate with the crysta

50 vious theory of overflow metabolism based on molecular crowding following the proteomic fractions for

51 This study suggests that molecular crowding forces can increase protein misfoldin

52 Indeed, increasing molecular crowding has been shown to modify the kinetics

53 the predominant product under conditions of molecular crowding; however, we also discovered that Rec

54 The data suggests molecular crowding impacts myosin conformation, implying

55 The results suggest that molecular crowding in cellular membranes has a dramatic

56 reactions in vitro; however, the effects of molecular crowding in living cells are mostly unexplored

57 Despite the ubiquity of molecular crowding in living cells, the effects of crowd

58 ere the myosin concentration is low suggests molecular crowding in the A-band promotes occupancy of t

59 lates the molecular composition and level of molecular crowding in the ER to the kinetic rates of pro

60 One possible factor could be molecular crowding in the neuronal cytoplasm.

61 ugh the binding of NTRs to FG Nups increases molecular crowding in the NPC transport channel, it is u

62 ery low permeabilities and a small effect of molecular crowding in volumes between the barriers.

63 presence of membranes, a condition mimicking molecular crowding induced by dehydration during freezin

64 As a model for understanding how molecular crowding influences diffusion and transport of

65 ively subtle changes in CA concentration and molecular crowding influencing self-assembly and the ens

66 We show that molecular crowding is a key factor in explaining the swi

67 alous diffusion in cells as a consequence of molecular crowding is not correct and that slowing of di

68 Instead, molecular crowding itself completely alters the mechanis

69 Apparently, the molecular crowding level that can inhibit the transport

70 Cells are densely packed with proteins, and molecular crowding may play an important role in cellula

71 Molecular crowding modifies biochemical reaction rates a

72 A combination of molecular crowding, non-ionic detergents, Mg(2+) ions, a

73 This is because the molecular crowding of non-polymerizing HbF offsets subst

74 smotically induced changes primarily through molecular crowding of solutes that affect channel activi

75 cattering was used to examine the effects of molecular crowding on an intrinsically disordered protei

76 s study provides insights into the effect of molecular crowding on FRET, and it offers a basis for in

77 ttractive model to investigate the effect of molecular crowding on ligand-induced protein folding, as

78 We review the effects of molecular crowding on solute diffusion in solution and i

79 recent studies have highlighted the role of molecular crowding on the effects of hypertonicity, the

80 The effects of "molecular crowding" on elementary biochemical processes

81 membrane surface binding sites, rather than molecular crowding or aggregation, which is the case for

82 Molecular crowding plays a significant role in regulatin

83 Our data is consistent with the idea that molecular crowding plays an important role in the stabil

84 s study highlights the often overlooked role molecular crowding plays in regulating molecular structu

85 vironmental factors, such as pH, salt, other molecular crowding reagents, and specifically designed "

86 These results suggest that molecular crowding represents a bound on the achievable

87 nation for significant sequestration even if molecular crowding results in a very low critical concen

88 ts on the single-molecule kinetics of solute molecular crowding, specifically focusing on GAAA tetral

89 We have shown previously that molecular crowding stabilizes folded RNA structures.

90 system causes spatio-temporal differences in molecular crowding states that are sufficient to drive a

91 Estimates of excluded volume effects due to molecular crowding suggest the oligomerization equilibri

92 The interactions may involve molecular crowding that favors coalescence of the hetero

93 In the case of molecular crowding, translational mobility was assessed

94 anges, possibly reflective of an increase in molecular crowding upon cell shrinkage.

95 rease in the effective membrane viscosity or molecular crowding upon membrane bending.

96 s and in the presence of dextran that causes molecular crowding verify a strict Ca2+ requirement of t

97 lational proteins to alleviate the effect of molecular crowding, we develop a model for cell growth b

98 ion signal was found to be more sensitive to molecular crowding, whereas the aptamer probe signal doe

99 ase activity of Hsp90 is highly sensitive to molecular crowding, whereas the ATPase activities of Hsp

100 on in cell volume and subsequent increase in molecular crowding which severely alters the biophysical

101 Molecular crowding, which is microtubule independent, ca

102 ormational change is altered dramatically by molecular crowding within the peptide monolayer.

103 se was insufficient in this regard, and that molecular crowding within the synapse is critical to pre