ライフサイエンスコーパス: molecular genetic

1 of the major landmarks of late 20th century molecular genetics.

2 have broad applications to gene therapy and molecular genetics.

3 Molecular genetics along with optogenetic and pharmacoge

4 hemical markers that serve as surrogates for molecular genetic alterations and identification of char

5 We showed that molecular genetic alterations in membrane lipid composit

6 The molecular genetic alterations underlying the development

7 The molecular-genetic alterations contributing to the pathog

8 or a more comprehensive understanding of the molecular-genetic alterations pivotal to the development

9 Molecular genetic analyses confirmed that these animals

10 Structure-guided molecular genetic analyses revealed that it has distinct

11 However, molecular genetic analyses suggest that autosomal common

12 ral cognitive ability) are highly heritable, molecular genetic analyses to date have had limited succ

13 Accordingly, cytogenetic and molecular genetic analyses, such as conventional karyoty

14 morphology, flow cytometry, cytogenetic, and molecular genetic analyses.

15 Molecular genetic analysis included sequencing of BEST1

16 ensively studied using both quantitative and molecular genetic analysis methods, both approaches lack

17 ally persistent silencing enables a detailed molecular genetic analysis of an inherited epigenetic st

18 mendous advances in our ability to perform a molecular genetic analysis of Chlamydia species.

19 Results of ophthalmologic examination and molecular genetic analysis of CNGB1.

20 The molecular genetic analysis of Gustatory receptor (Gr) ge

21 The molecular genetic analysis of longevity of Caenorhabditi

22 ssical genetics and three-point crosses with molecular genetic analysis of recombinants to generate t

23 Molecular genetic analysis of the RS1 was performed and

24 Molecular genetic analysis of the switch-like regulation

25 Molecular genetic analysis revealed unexpected roles for

26 out to determine suitability of the gDNA for molecular genetic analysis.

27 In this report, using molecular genetics, analytical chemistry, and mass spect

28 Here, we review the molecular genetic and clinical features of inherited neu

29 lysis, are rapidly changing the landscape of molecular genetic and genomic testing.

30 on all these fronts, driven in large part by molecular genetic and optogenetic approaches that are be

31 Molecular genetics and biochemical approaches reveal tha

32 Here, using molecular genetics and biochemical approaches, a series

33 id dominant plant, is fast becoming a useful molecular genetics and bioinformatics tool due to its ke

34 Developments in molecular genetics and brain imaging may clarify how bra

35 ng the paradigm of what is possible in wheat molecular genetics and breeding.

36 Here we combine a proteomic study with a molecular genetics and cell biology approach to determin

37 avenues of research including epidemiology, molecular genetics and cell biology have identified link

38 Here, we explore the molecular genetics and cell biology that govern jaw join

39 resolution, we show through a combination of molecular genetics and chemical perturbations that direc

40 manipulation, land-use and habitat surveys, molecular genetics and demographic and spatial modelling

41 rphological features, but recent progress in molecular genetics and embryology has revealed deep simi

42 y interesting regions of the genome for both molecular genetics and evolutionary studies; yet, for mo

43 Here we used molecular genetics and in vivo calcium imaging to invest

44 Improving our understanding of molecular genetics and leukemic transformation holds pro

45 Moreover, the use of molecular genetics and new experimental strategies has b

46 Molecular genetics and observational case studies of 2 f

47 ause of advances in the understanding of the molecular genetics and pathogenesis of the disease, inco

48 d by the gap between cellular immunology and molecular genetics and profited from the advances of the

49 Here, molecular genetics and structure-activity analyses show

50 Technological advancements in fields such as molecular genetics and the human microbiome have resulte

51 We used molecular, genetic and biochemical techniques to examine

52 an embryo development that combines imaging, molecular, genetic and epigenetic data for comparisons t

53 Kcnj2 is expressed in the nascent face; (2) molecular-genetic and biophysical techniques are availab

54 lved mPFC-to-NAc projection displayed unique molecular-genetic and microcircuit-level features concor

55 Using a combination of pharmacologic, molecular genetic, and behavioral studies in mice, we de

56 rophysiological, neuroimaging, pathological, molecular genetic, and biochemical studies, as well as s

57 n this study, we use multiple human genetic, molecular genetic, and cellular assays to identify a fun

58 tz crystal microbalance, circular dichroism, molecular genetics, and immunofluorescence to study spec

59 plication of modern chemistry, biochemistry, molecular genetics, and optical physics to these old str

60 isciplinary approach combining biochemistry, molecular genetics, and structural biology, that meningo

61 Molecular, genetic, and electrophysiological evidence in

62 hila melanogaster plays an important role in molecular, genetic, and genomic studies of heredity, dev

63 n to regulate sleep, and provide anatomical, molecular, genetic, and pharmacological evidence that NP

64 Transgenic, immunohistochemical, molecular-genetic, and fluorescence imaging approaches r

65 endogenous restriction sites for downstream molecular genetic applications.

66 We therefore used a molecular genetic approach and found that PTP was unaffe

67 Here, we describe a molecular genetic approach, using a collection of chimer

68 an integrated genomics, bioinformatics, and molecular genetics approach to dissect regulatory networ

69 Here we explore a molecular genetics approach to restrict the assimilation

70 Molecular genetic approaches in the mouse have led to th

71 e have used biochemical, cell biological and molecular genetic approaches to demonstrate that beta8 i

72 Here we use molecular genetic approaches to examine microbial commun

73 Using molecular genetic approaches to target different neurona

74 patients with SCZ; however, until recently, molecular genetic approaches to test this overlap have b

75 We have employed molecular genetic approaches to understand the domain or

76 pollen, and starch grains), biochemical and molecular genetic approaches, and dating through (14)C a

77 More recently, molecular genetic approaches, including genome-wide stud

78 Molecular genetic approaches, including targeted next-ge

79 s serology and biotypes, to much-more-robust molecular genetic approaches, such as pulsed-field gel e

80 Here we show, using molecular genetic approaches, that the MYB transcription

81 Using biochemical and molecular genetic approaches, we identified three tropom

82 Here, using comparative genomics and molecular genetic approaches, we reveal that the capacit

83 The utilization of molecular genetics approaches in examination of panic di

84 To better understand the cellular and molecular genetic aspects of this disorder, we generated

85 ted image identification and developments in molecular genetic assays offer considerable promise for

86 Broad molecular genetic assessments affirm reproductive isolat

87 Examining 20 730 individuals, we report a molecular genetics-based heritability estimate (h(2)SNP)

88 Despite this, very little is known about the molecular genetic bases of tiller development in importa

89 This study provides the first clear molecular genetic basis for an OTCS case, indicates that

90 To begin to understand the molecular genetic basis for transcriptional regulation o

91 mparative genomic analysis we identified the molecular genetic basis of 99.8% of the antimicrobial re

92 Additional studies are needed to explore the molecular genetic basis of heterosis and outbreeding dep

93 To deepen our understanding of the molecular genetic basis of lignocellulose recalcitrance,

94 Advances in our understanding of the molecular genetic basis of mitochondrial disease have no

95 These findings provide insights into the molecular genetic basis of PME and show the role of de n

96 The molecular genetic basis that leads to Lewy Body (LB) pat

97 enetic and biochemical characterization, the molecular genetic basis underlying the biosynthesis of b

98 However, the molecular genetic basis underlying the quantitative vari

99 are yet to have a clear understanding of its molecular-genetic basis.

100 Here, we use molecular genetic, behavioral, and anatomical studies in

101 There are significant differences in molecular genetics between pancreatic and extrapancreati

102 Using a combination of molecular genetic, biochemical, and single-molecule biop

103 We use molecular genetics, biochemical analyses, and experiment

104 However, recent molecular, genetic, biochemical, and genomic studies hav

105 owever, little is known about the underlying molecular genetics, biochemistry, or physiology of L. he

106 We used a combination of molecular, genetic, bioinformatic and phylogenetic analy

107 s, which has many of the advantages of yeast molecular genetics but uses long-range microtubule-based

108 none of these case subjects were linked to a molecular genetic cause.

109 All together, these findings elucidate the molecular genetic causes of UHS and shed light on its pa

110 Despite much theoretical work, the molecular-genetic causes and evolutionary consequences o

111 Of particular interest are those molecular genetic changes that are associated with the d

112 In this study we report the molecular genetic characterization of the Arabidopsis mi

113 AtGATL5]) was studied using a combination of molecular genetic, chemical, and immunological approache

114 , clinical trials, psychiatric epidemiology, molecular genetics, children, and other cultures are dis

115 Understanding the molecular genetic circuitries underlying thermomorphogen

116 These data establish the basis for a molecular genetic classification of clear-cell renal-cel

117 lopment and set the foundation for the first molecular genetic classification of the disease, paving

118 ays, have been defined, leading to the first molecular/genetic classification of the disease.

119 stigations have just begun to illuminate the molecular genetic contributions to major psychiatric ill

120 In addition, molecular genetic correlations for the subcategories of

121 Here, we provide molecular, genetic, cytological, and biochemical evidenc

122 (PGC-PTSD) combined genome-wide case-control molecular genetic data across 11 multiethnic studies to

123 The new molecular genetic data, especially those derived from ne

124 Modern molecular genetic datasets, primarily collected to study

125 Both pharmacological and molecular genetic decreases in hippocampal AChE activity

126 rently prevent using this model to study the molecular genetic details before or during tubule induct

127 Molecular genetic details of the human coagulation syste

128 The molecular genetic determinants of essential tremor are u

129 f anterior vitreous (SLAV), and clinical and molecular genetic diagnoses were documented.

130 the unsolved cases, our assay resulted in a molecular genetic diagnosis for 35 of 139 patients.

131 The availability of molecular genetic diagnosis has opened up a new field fo

132 e early-onset epilepsy, precise clinical and molecular genetic diagnosis is complex, as many metaboli

133 tients with complex III deficiency without a molecular genetic diagnosis.

134 Our study results should facilitate molecular genetic diagnostics of SRNS, etiologic classif

135 has ushered in a new paradigm for the use of molecular genetic diagnostics to guide targeted therapie

136 t in the modern era, especially given recent molecular genetic discoveries.

137 tation of non-coding genetic variants in the molecular genetic dissection of brain disorders.

138 Drosophila model will enable a sophisticated molecular genetic dissection of cold nociceptive genes a

139 ing this review is the anticipation that the molecular genetic dissection of the integrated host immu

140 ap in knowledge, we present the results of a molecular genetic dissection of the TFIID subunit Taf2.

141 r, due in part to the difficulty of studying molecular genetic effects in humans, even the current co

142 rrent classification system, histopathology, molecular genetics, electrophysiology, and transcriptome

143 en impeded by an inadequate understanding of molecular genetic elements governing tumor progression.

144 However, precise biochemical and molecular genetic elucidation of metabolic resistance ha

145 rone therapy in vivo by using physiological, molecular, genetic, endocrine and biochemical markers an

146 Molecular genetic estimates of Ne computed from linkage

147 We additionally calculated two single-sample molecular genetic estimates of Ne to corroborate the dem

148 In this molecular genetic evaluation of 91 cases of intrauterine

149 However, the molecular genetic events driving these behaviours are un

150 The research also provides strong molecular genetic evidence for an important role of SA i

151 Here we provide definitive molecular genetic evidence supported by biochemical, cel

152 Together, our study provides the first molecular genetic evidence that mechanosensory ion chann

153 These findings provide molecular genetic evidence that risk alleles for the cat

154 Using public data and data from our own molecular genetic experiments (quantitative PCR, Western

155 Molecular genetic experiments are revealing how the fly

156 urther define the clinical, pathological and molecular genetic features of this disorder.

157 We report the detailed clinical features, molecular genetic findings and in vitro functional inves

158 To describe the detailed clinical and molecular genetic findings in a series of patients with

159 linical, electrophysiologic, structural, and molecular genetic findings in nonsyndromic inherited ret

160 he combination of clinical, biochemical, and molecular genetic findings must be considered to obtain

161 In summary, these molecular genetic findings support the concept that clas

162 This molecular genetic framework of neuronal identity integra

163 Moreover, little is known about the molecular genetic functions of NEUROG3 in human islet de

164 As the scope of assays used in molecular genetics has expanded to capture systems-level

165 The development of molecular genetics has greatly enhanced the study of the

166 nt research using methodological advances in molecular genetics has improved our understanding of the

167 The advent of molecular genetics has in the past several years aided c

168 Advances in cell type-specific molecular genetics have now helped to elucidate several

169 Advances in molecular genetics have vastly improved our understandin

170 reater number of models that capture greater molecular/genetic heterogeneity of the cancer type.

171 ggesting these cells' utility to dissect T2D molecular genetics in these regions.

172 Molecular genetics, in vitro assays, and expression data

173 ade available here afford the best-available molecular genetic index of PTSD-for both European- and A

174 as opportunities presented by incorporating molecular genetics into these efforts.

175 The molecular genetic investigation included bidirectional S

176 Molecular genetic investigations have revealed mutations

177 comprehensive characterisation of the entire molecular genetic landscape of meningioma to identify bi

178 ght; however, it is poorly understood at the molecular genetic level.

179 Chlamydia is experiencing a renaissance for molecular genetic manipulation.

180 Firmicutes bacterium that is intractable to molecular genetic manipulation.

181 uding Chlamydia, are not amenable to routine molecular genetic manipulations.

182 Molecular genetic mapping positioned the turnout mutatio

183 t decisions are based on a limited number of molecular genetic markers and morphology-based assessmen

184 ancer, investigators have sought to identify molecular genetic markers that stratify newly diagnosed

185 sment of cytogenetics and a limited panel of molecular genetic markers, coupled with morphological as

186 In this report, we investigated the molecular genetic mechanism underlying the deafness-asso

187 amental form of learning, yet the underlying molecular genetic mechanisms are not well defined.

188 Understanding the molecular genetic mechanisms of development and function

189 Little is known, however, about the molecular genetic mechanisms that control the formation

190 radiation-induced breast carcinogenesis, the molecular genetic mechanisms that underlie cell transfor

191 The molecular genetic mechanisms underlying abaxial-adaxial

192 To obtain new information about the molecular genetic mechanisms underlying carriage of grou

193 genetic variants and could elucidate shared molecular genetic mechanisms.

194 nia and cognitive function, suggesting novel molecular genetic mechanisms.

195 are usually qualitative models derived from molecular-genetic mechanisms for DNA repair, DNA synthes

196 These results provide insight into the molecular-genetic mechanisms of the biosynthesis and dep

197 these data allow for the elucidation of the molecular-genetic mechanisms that generate SSD, an impor

198 ticism; using formal genetic twin models and molecular genetic methods, i.e. polygenic risk scores (P

199 ell type, therefore, represents an excellent molecular-genetic model to study the biosynthesis and mo

200 Recent findings from molecular genetics now make it possible to test directly

201 we provide a state-of-the-art review of the molecular genetics of ADHD incorporating evidence from c

202 Recent advances in our knowledge of the molecular genetics of AML have significantly improved ou

203 these data provide key new insights into the molecular genetics of form and function in the mammalian

204 Extraordinary progress accomplished in molecular genetics of inherited cardiomyopathies allowed

205 een a revolution in our understanding of the molecular genetics of insecticide resistance.

206 Here, I review the molecular genetics of meiotic silencing and consider the

207 associated with cardiac arrhythmias, and the molecular genetics of monogenic disorders of heart rhyth

208 a major advance in our understanding of the molecular genetics of NCMD and provide insights into the

209 An improved understanding of the molecular genetics of OS may yield new approaches to imp

210 ology in increasing our understanding of the molecular genetics of PAD.

211 Therefore, understanding the molecular genetics of palate development is important fr

212 The molecular genetics of panic disorder (PD) with and witho

213 ciation study (GWAS) data set available, the Molecular Genetics of Schizophrenia (MGS) data set.

214 Recent work on the molecular genetics of speciation has raised an altogethe

215 ome editing] will be critical to dissect the molecular genetics of T2DM pathogenesis, to build next-g

216 nderpinnings, little else is known about the molecular genetics of this frequently fatal cancer.

217 Recent advances in the molecular genetics of uveal melanoma are revolutionizing

218 ing data, our findings shed new light on the molecular genetics of uveal melanoma, delineating it as

219 his issue, we took advantage of the power of molecular genetics of yeast.

220 esence of VEGF stimulation was combined with molecular genetics, optical imaging, and biochemistry to

221 Here, I review recent applications of molecular genetic, optogenetic, and pharmacogenetic appr

222 Combined with technologies for single-cell molecular genetics or cell biology, it may significantly

223 utcome despite the inevitable variability at molecular, genetic, or environmental levels.

224 This is the first report elucidating a molecular genetic pathway downstream of Lhx in palate de

225 Here we delineate a molecular-genetic pathway governing LCD in C. elegans.

226 Using molecular genetics, plant physiology, hormone analysis a

227 We examined the interactions between a molecular genetic predisposition to various aspects of o

228 which understanding these organism-level and molecular genetic processes can be used for crop plant i

229 ice has led to fundamental insights into the molecular genetic processes that govern cancer initiatio

230 ure models and apply them in the analysis of molecular genetic prognostic factors for disease-free su

231 The molecular genetic program for root hair development has

232 Here we applied molecular genetics, proteomics, and whole-genome sequenc

233 identified from NGS databases at three large molecular genetics reference laboratories.

234 at are gaining considerable attention in the molecular-genetic regulatory mechanisms that contribute

235 onset of high blood pressure; however their molecular genetic relationship (s) and sex-specific dete

236 The molecular genetic relationship between esophageal adenoc

237 The results inform molecular genetics research and transdiagnostic treatmen

238 ine max) and the availability of appropriate molecular-genetic resources have allowed us to directly

239 Recent advancements in molecular genetics resulted in the identification of gli

240 Molecular genetic results and details of clinical phenot

241 sotope and isotopomer signatures, as well as molecular genetic results, also point towards a major sh

242 (HSVtk) gene, which has a dual function as a molecular-genetic sensor/reporter and a cell suicide-ind

243 e rearrangements, not detectable by standard molecular genetic sequencing techniques, are present in

244 ccount the most current information on virus molecular genetics, serology, and host reactivity.

245 tracheophytes, yet little is known about its molecular genetic specification.

246 g of actin gene transcription, combined with molecular genetics, stochastic simulation and probabilis

247 genes, should boost the statistical power of molecular genetic studies and clarify the pathophysiolog

248 Molecular genetic studies and twin studies have confirme

249 espite recent insights from quantitative and molecular genetic studies demonstrating considerable ple

250 Correlated clinicopathologic and molecular genetic studies gave rise to a dualistic model

251 Molecular genetic studies have also shown that common ph

252 Molecular genetic studies have identified transduction a

253 Molecular genetic studies have revealed the functional b

254 rved between yeast and other eukaryotes, and molecular genetic studies in budding yeast have provided

255 Contemporary molecular genetic studies in Drosophila melanogaster and

256 Molecular genetic studies of model plants in the past fe

257 Clinical and molecular genetic studies over the course of the last 50

258 We demonstrate by molecular genetic studies that SEEDSTICK (STK), a transc

259 aenorhabditis elegans have been deployed for molecular genetic studies to inform on key components of

260 Most molecular-genetic studies of plant defense responses to

261 of differentiation arrest between different molecular genetic subtypes of human T-ALL.

262 large part due to a paucity of resources for molecular genetics, such as a reference genome.

263 This provides molecular genetic support for a paradigm shift in theori

264 ericans (AAs), but little is known about the molecular genetic susceptibility.

265 es for other stimuli and providing potential molecular genetic targets for engineering drought-resist

266 Recent development of molecular genetic techniques are rapidly advancing under

267 Over the past 20 years molecular genetic techniques have provided a new approac

268 Using different molecular genetic techniques, we identified 20 patients

269 Molecular genetics techniques are an essential diagnosti

270 of the present study is to provide the first molecular genetic test of the classic endophenotype hypo

271 ulinaemic hypoglycaemia include use of rapid molecular genetic testing for the disease, application o

272 ns as well as the significance of performing molecular genetic testing in mildly affected patients ar

273 ude ADPKD particularly in younger donors and molecular genetic testing is advised.

274 Results of clinical assessment and molecular genetic testing.

275 throcyte protoporphyrin (ePPIX) testing, and molecular genetic testing.

276 nce tomography (SD-OCT), microperimetry, and molecular genetic testing.

277 atients (24%) the mutation was verified with molecular genetic testing.

278 Amassing greater knowledge on the molecular genetics that underlie tree form can benefit t

279 Here we investigated, using molecular genetics, the conservation and diversification

280 We exploited Arabidopsis molecular genetics to define the mechanism and regulatio

281 Here, we employed bioinformatics and molecular genetics to identify and characterize MATE tra

282 genomics, bioinformatics, metabolomics, and molecular genetics to identify and validate molecular ne

283 bine structure-based protein engineering and molecular genetics to restrict the activity of the poten

284 Here, we use molecular genetics to show that the moss Physcomitrella

285 h, integrating the tools of quantitative and molecular genetics to study developmental processes, and

286 review summarizes the current status of the molecular genetic toolbox for Chlamydia species and high

287 The molecular genetic toolkit of the Mexican axolotl, a clas

288 Molecular genetic tools have had a profound impact on ne

289 without the development of species-specific molecular genetic tools.

290 ontinuous culture, facile animal models, and molecular genetic tools.

291 ns, we understand little about the bacterial molecular genetic underpinnings of this phenomenon.

292 e to determine whether a composite of common molecular genetic variants, previously found to be assoc

293 ive C. remanei possesses very high levels of molecular genetic variation and low levels of linkage di

294 Estimates of molecular genetic variation are often used as a cheap an

295 sufficient for characterising a population's molecular genetic variation at comparable markers.

296 Examining patterns of molecular genetic variation in both modern-day and ancie

297 However, this evidence is based on molecular genetic variation poorly predicting estimates

298 By combining computational modeling with molecular genetics, we show that boundary formation is d

299 Using molecular genetics, we then mapped at which point in the

300 Combining molecular genetics with target-based approaches, we esta