ライフサイエンスコーパス: molecular level

1 -degrading bacteria at the physiological and molecular level.

2 l compounds, though poorly understood at the molecular level.

3 ne might expect corresponding changes at the molecular level.

4 biological effects of NGF and proNGF at the molecular level.

5 tigation of the influence of knotting at the molecular level.

6 tand the adsorption of chiral compounds at a molecular level.

7 zed actuation of the mechanical bonds at the molecular level.

8 spatial resolution approaching virtually the molecular level.

9 r understanding of how cells function at the molecular level.

10 these mutations enable host adaptation on a molecular level.

11 to better understand ADP-ribosylation at the molecular level.

12 dapted species never described before at the molecular level.

13 , yet they are rarely well understood at the molecular level.

14 cture of the DASA isomerization pathway on a molecular level.

15 ough specific mechanisms poorly known at the molecular level.

16 he bacterial reductive dehalogenation at the molecular level.

17 erized the cation-preferring channels at the molecular level.

18 how genetic variants influence traits at the molecular level.

19 sable to understanding their mechanisms on a molecular level.

20 sed on spin-polarized currents controlled at molecular level.

21 mode of action of these biomolecules at the molecular level.

22 promotes BAT dysfunction, especially at the molecular level.

23 h DUB specificity has been understood at the molecular level.

24 host-I2 and I2-I2 binding interactions at a molecular level.

25 comparison of human and mouse biology at the molecular level.

26 ogical processes in cells and tissues at the molecular level.

27 erstand evolution of assortative mating at a molecular level.

28 in temporal cortex, suggesting a role at the molecular level.

29 better understanding of the technology at a molecular level.

30 Kdo-N3 incorporation into E. coli LPS at the molecular level.

31 terise how well these interfaces work at the molecular level.

32 te and visualize the electrostatic forces at molecular level.

33 diverse cells perceive ECM alignment at the molecular level.

34 which constitute fundamentals of life on the molecular level.

35 no- and oligosaccharides was assessed at the molecular level.

36 esponding birch pollen allergen Bet v 1 at a molecular level.

37 al sciences, but it is not understood at the molecular level.

38 ubstrates, alpha-Fe2O3 nanoparticles, at the molecular level.

39 DNA robot that performs cargo sorting at the molecular level.

40 lved in this tolerance remain unclear at the molecular level.

41 sm seems to be different from mammals at the molecular level.

42 cell surface adhesion at the functional and molecular level.

43 how such interactions emerge and evolve on a molecular level.

44 vailable tools to mimic such structures at a molecular level.

45 s are insufficiently understood at the basic molecular level.

46 gistics of working with these creatures at a molecular level.

47 efore allow investigation of phenotypes at a molecular level.

48 to our understanding of cell membranes at a molecular level.

49 function, yet it is poorly understood at the molecular level.

50 ssion to humans and initial infection at the molecular level.

51 mputational model of toxin production at the molecular level.

52 yers of water on Ru(0001) and Pt(111) at the molecular level.

53 ed pseudotyping, is poorly understood at the molecular level.

54 ediates at the solid-liquid interface at the molecular level.

55 er matrices to mimic biological systems at a molecular level.

56 n is surprisingly difficult to obtain at the molecular level.

57 active T cells and characterized them at the molecular level.

58 ledge of how drugs interact with P-gp at the molecular level.

59 ing the cell's nanoscale architecture at the molecular level.

60 e sub-atomic, atomic, supra-atomic, or supra-molecular level.

61 ure's solution for directing movement at the molecular level.

62 s for modeling neurological disorders at the molecular level.

63 on and outcome of the immune response at the molecular level.

64 t where we can truly connect the dots at the molecular level.

65 (Cyt) b6f within thylakoid membranes at the molecular level.

66 rvr1 is similar to the vernalized state at a molecular level.

67 ships, but is often poorly understood at the molecular level.

68 ge of the proteome-wide interaction space at molecular level.

69 understand interspecies PrP propagation on a molecular level.

70 ly due to species separation enforced at the molecular level.

71 ehensive picture of energy conversion at the molecular level.

72 stics disclosed also a high heterogeneity at molecular level.

73 de materials can be tuned rationally, at the molecular level.

74 e clarified at the population, cellular, and molecular levels.

75 as evaluated at morphologic, histologic, and molecular levels.

76 t effects can be produced at the circuit and molecular levels.

77 ively at the whole-heart, cardiomyocyte, and molecular levels.

78 tic insights on how it works at cellular and molecular levels.

79 ental effects of ageing at morphological and molecular levels.

80 at the clinical, pathological, cellular, and molecular levels.

81 responses, very little is understood at the molecular level about the initial sensing of environment

82 On the molecular level, after adjusting for intrinsic subtype f

83 and zero-dimensional (0D) structures on the molecular level all possible.

84 ombus formation are yet to be defined at the molecular level, allosteric disulfide bonds that are mod

85 A molecular level analysis showed increased FIBROBLAST ACT

86 Here, we report the first molecular-level analysis of growth and morphogenesis in

87 The etiology is not well understood on a molecular level and causal agents show a great diversity

88 of action of several KCa3.1 blockers at the molecular level and could be used for structure-assisted

89 al knowledge about interacting partners on a molecular level and focusing comparative sequence analys

90 in both living and nonviable systems at the molecular level and has a high potential on early diagno

91 disease progression at both the cellular and molecular level and identify A20 as a novel downstream s

92 late transport has been characterized at the molecular level and is performed by at least one carrier

93 e a fundamental understanding of life at the molecular level and lead to important applications to bi

94 acilitated by host-guest interactions at the molecular level and nanofibril formation at colloidal-le

95 l-time will help understand the changes on a molecular level and offers us a basis to understand the

96 rities between Gs and Golf activation at the molecular level and provides a novel set of tools to sea

97 rgen molecules dissect the IgE response on a molecular level and put allergy research on the map of p

98 e a rare glimpse of silicon chemistry on the molecular level and shed light on the remarkable non-adi

99 We perform perturbations of molecular levels and sensitivity analyses to predict how

100 d adult reticulocytes functionally or at the molecular level, and importantly no aberrant protein exp

101 m umbilical cord's Wharton's Jelly (WJ) on a molecular level, and potentially render them unsuitable

102 hromosomes has not been characterized at the molecular level, and the degree of sequence variation am

103 etic proton undergo ionization at individual molecular level, and the excitation primarily derives fr

104 ontribute to deciphering Ub signaling at the molecular level, and with the synthetic tools in hand, c

105 To address this deficiency a biomimetic molecular-level approach is developed that employs light

106 control and to understand the phenomena at a molecular level are scarce.

107 he non-covalent interaction is to direct the molecular-level arrangement (or disposition) of the tect

108 there is little mechanistic evidence at the molecular level as to how changes in temperature are tra

109 d via insect vectors, little is known at the molecular level as to how the viruses are recognized and

110 understand antibody-mediated immunity at the molecular-level based on the direct determination of ser

111 ems, can provide criteria for a rational and molecular level-based design of AMPDs.

112 At the molecular level, bioenergetic challenges result in the a

113 nt maturation (SFTP-B, SFTP-D, ABCA3) at the molecular level, but did not alter the numerical density

114 potent states have been characterized at the molecular level, but their biological importance remains

115 nective tissue disorder characterized at the molecular level by a loss of telopeptide lysine hydroxyl

116 omochiral or heterochiral aggregation at the molecular level by chiral and prochiral adsorbates on su

117 In these processes, forces generated at the molecular level by motor proteins are transmitted by dis

118 We validated the network architecture at the molecular level by native polyacrylamide gel electrophor

119 regulated steps that are orchestrated at the molecular level by specific cyclins that act in associat

120 developing world and are characterized on a molecular level by the presence of genes that encode the

121 ges a divide, showing how replication at the molecular level can be used to drive macroscale droplet

122 nderlying plant biomass recalcitrance at the molecular level can only be achieved by accurate analyse

123 planations for microcephaly are supported by molecular level changes that may have increased its viru

124 The molecular level characterization of erWalK will not only

125 Here we present a molecular-level characterization of a clinical-grade por

126 Here, we present the first molecular-level characterization of temporal composition

127 coupled these macroscopic measurements with molecular-level characterization of the polysaccharide c

128 At the molecular level, CLP inhibited the activity of the ubiqu

129 M mutations cause compound phenotypes at the molecular level, combining compromised DNA binding with

130 erences in the dynamics of ILs in SILMs on a molecular level compared to the bulk IL, and the study o

131 se, bulk chemical properties (O:C, H:C), and molecular-level composition of SOA formed from the ozono

132 rin-mediated traction forces at the bulk and molecular levels, consistent with a motor-clutch model i

133 sophisticated interfacial design, often with molecular level control, but we have no tools to charact

134 Certain benefits to this approach are molecular-level control of composition, improved routes

135 nction of such a repression mechanism at the molecular level could lead to a disturbance of later eve

136 ransport resonances associated with discrete molecular levels could play a key role in thermoelectric

137 These data provide a molecular-level description of how antibodies derived fr

138 of de novo design-allowing for the bottom-up molecular-level design of genetic control systems.

139 therapeutic strategies, but visualizing the molecular-level details of this exchange has been diffic

140 This work provides molecular-level details that dictate a nanoparticle's el

141 ost, user-friendly, and enhanced sensitivity molecular-level diagnostics.

142 At the molecular level, DrugCentral bridges drug-target interac

143 At the molecular level, DUSP3 deletion was associated with estr

144 s emerge from metabolic regulation, from the molecular level (e.g. homeostasis of total metabolite po

145 s of such assemblies in cell biology and (3) molecular-level engineering of self-assembled recombinan

146 ochemistry offers exciting opportunities for molecular-level engineering of stress-responsive propert

147 RATIONALE: Stratification of asthma at the molecular level, especially using accessible biospecimen

148 Our findings also provide a molecular-level explanation for the observation that syn

149 These molecular-level findings provide important insights into

150 At the molecular level, FOXP1 regulated cell-fate choice of MSC

151 We apply this new technique to elucidate the molecular-level geometry of (13)C-enriched methionine an

152 ity to study disease at the most fundamental molecular level has led to a reclassification of human c

153 The classification of samples on a molecular level has manifold applications, from patient

154 g the electrostatics of lipid membranes at a molecular level has the potential to offer great insight

155 At the molecular levels, hepatic Foxo1/3/4 deficiency triggered

156 On the molecular level, hG9a interacted with histone acetyltran

157 d nine Btk inhibitors and characterized on a molecular level how their interactions with Btk define t

158 ortant step forward in understanding, at the molecular level, how a major agricultural pest promotes

159 At the molecular level, Id1 directly interacts with and suppres

160 , including i) adverse effect; ii) effect at molecular level; iii) effect related to pharmacokinetics

161 At the molecular level, IL10 treatment significantly inhibited

162 At the molecular level, immediate early genes are among the syn

163 ions how plasma-generated RONS interact on a molecular level in a biological environment, e.g. cells

164 omplex influence of extrinsic factors at the molecular level in breast cancer.

165 our understanding of carbon speciation at a molecular level in meteorite parent bodies.

166 tends those observations to the cellular and molecular level in the centrilobular phenotype of emphys

167 logues are prepared and characterized at the molecular level, in particular by solid-state NMR, and t

168 The effect is echoed, at the molecular level, in the observed trend in Ecell, the ele

169 ong 5-HT neuron subtypes at the cellular and molecular levels, including differences in the capacity

170 surface patterning, opening new avenues for molecular level information storage, and boosting the em

171 merged as a powerful approach to provide key molecular-level information about active-site structures

172 In particular, DNP SENS provides molecular-level information about the structure of surfa

173 Our results provide new and direct molecular-level information for a key component needed f

174 agnosis and treatment of disease by allowing molecular-level information to be used during routine me

175 n given the difficulty in assessing detailed molecular-level information.

176 lecular resolution of this approach offers a molecular-level insight into the dynamics of these bioin

177 vel of single GAG chains, which provides new molecular-level insight into the role of mechanical forc

178 chanism of such processes, as they provide a molecular-level insight of structural and electronic cha

179 ndividuals' health states with real-time and molecular-level insight.

180 The second overviews the molecular-level insights derived from microkinetic and t

181 Our studies provide molecular-level insights into how polyphenols inhibit Ab

182 Together, our study provided molecular-level insights into the impacts of the carboxy

183 Our simulations offer molecular-level insights into ultrafast photoinduced cha

184 noparticles (e.g., Au38), but also represent molecular-level insights on long-standing puzzles in nan

185 rn multi-herb prescriptions through rigorous molecular-level investigations and standardized clinical

186 Information relay at the molecular level is an essential phenomenon in numerous c

187 A deeper understanding of mechanics at the molecular level is essential for the design and construc

188 f host-microbiota interactions (HMIs) at the molecular level is important since it may provide insigh

189 al and phase transformations of water at the molecular level is key to understanding a variety of mul

190 ems, gaining clear mechanistic detail at the molecular level is key towards understanding the operati

191 However, the detail at the molecular level is largely unknown.

192 pH-dependent inhibition of PME occurs at the molecular level is missing.

193 etailed knowledge of aerosol components at a molecular level is needed.

194 tions of calcium with lipid membranes at the molecular level is of great importance in light of their

195 tween extrinsic and intrinsic factors at the molecular level is one promising route to identifying th

196 How this switch is orchestrated at the molecular level is poorly understood.

197 tion of the CKD onset and progression at the molecular level is still not fully understood.

198 y of DENND3 toward Rab12 is regulated at the molecular level is still not understood.

199 retinal dystrophy, but how this arises at a molecular level is unclear.

200 animals and humans and its regulation at the molecular level is unknown.

201 post-pollination response of flowers at the molecular levels is unclear.

202 understanding of soil organic matter at the molecular level itself key to develop the most efficient

203 At the molecular level, KLF6 suppresses BCL6 mRNA and protein e

204 At the molecular level, ligand-mediated AR activation is coordi

205 sport mechanisms have been discovered at the molecular level, little is known about the factors regul

206 The ability to use asymmetry to operate molecular-level machines or macroscopically functional d

207 print of MB in birds to characterize, at the molecular level, MB in the non-avian theropod Tyrannosau

208 ts from logistic regression, text-mining and molecular-level measures for comorbidities such as genet

209 construct a drug-specific pathway in which a molecular-level mechanism of action is formulated based

210 However, the molecular-level mechanisms of kinetic stabilization are

211 oscopic properties, potentially by different molecular-level mechanisms.

212 s have improved correspondence with expected molecular-level mechanisms.

213 inment by light is well characterized at the molecular level, mechanisms that underlie the direct eff

214 These results provide a detailed, molecular-level, mechanistic picture of how Gnd(+) influ

215 On a molecular level, metoprolol expectedly decreased protein

216 On the molecular level, microglial transforming growth factor-b

217 o reveal the mechanism of these disorders at molecular level, mobility and spatial rearrangements of

218 At a molecular level, mutations in nine different genes can l

219 adients, even in the presence of significant molecular-level noise.

220 The surprisal-based model captures important molecular-level nonequilibrium physics, yet the simple f

221 ies of chemically simple systems, but direct molecular-level observations of nucleation in atmospheri

222 This work targeted a molecular level of understanding on the dynamics of humi

223 ransmission are regulated independently on a molecular level or whether they are simply a continuum o

224 At the molecular level, our unbiased transcriptome profiling sh

225 It is therefore feasible that molecular-level patient information could be used to dec

226 Examination of molecular-level performance is necessary for improved as

227 Importantly, Raman spectroscopy revealed molecular-level perturbations of fibril conformation by

228 Developing nanotechnology that would allow molecular-level phenomena to drive such movements in art

229 ith experimental observations and provides a molecular-level picture of how E1P to E2P enzyme conform

230 ATP, NADH, and acetyl-CoA (Figure 1 ) at the molecular level play such central roles.

231 At the molecular level, Plk1 overexpression led to reduced phos

232 Here, we extend such molecular-level precise reaction routes to nanochemistry

233 is review ranges from the purely fundamental molecular-level processes that govern solvent behavior t

234 es and present new avenues for understanding molecular-level properties influencing expression and so

235 At the molecular level, rapid radiation with successive speciat

236 This provides a molecular-level rationale for the exposure of the hydrop

237 olecular dynamics simulations to resolve the molecular level recognition mechanisms and calculate the

238 ssure versus passive drift in evolution on a molecular level, refutes the debated activity/stability

239 of CcO, yet the underlying mechanism at the molecular level remains lacking.

240 The pathogenesis of NSDs at the molecular level remains poorly understood.

241 tate influence the duration of memory at the molecular level remains unknown.

242 y induce beiging differently at cellular and molecular levels remains unclear.

243 The realization of complex topologies at the molecular level represents a grand challenge in chemistr

244 gineering nanoparticle (NP) functions at the molecular level requires a detailed understanding of the

245 of a gene's expression and regulation at the molecular level requires identification of all proteins

246 efficient access to sequence control at the molecular level, resulting in topologies with specific e

247 At the molecular level, RIN1 signals through Rab5 GTPases that

248 stereomers that cannot be deracemized at the molecular level, self-organize to form single-handed hel

249 ddress immunological IgE cross-reactivity on molecular level, seven recombinant antigens 5 of the mos

250 A new study characterizes AlmG at the molecular level, showing it defies phylogenetic expectat

251 rtance of integrating phenotypic data at the molecular level (signaling and gene expression) with tho

252 on can be segregated at least partially on a molecular level.SIGNIFICANCE STATEMENT Action potential-

253 Here we combine nanoscale experiments with molecular-level simulation to study the breakdown of sph

254 currently very challenging to determine the molecular-level structure(s) of these peptides in the ma

255 nt to connect the macroscopic faces with the molecular-level structure.

256 ollagen by triple helix formation, to detect molecular level subfailure damage to collagen in mechani

257 tory mechanism utilized by green plants on a molecular level that allows them to safely dissipate the

258 ally important biomarkers at the circuit and molecular level that can now be explored in patients wit

259 chemicals to identify proximal cells at the molecular level that can participate in cooperative proc

260 We have proved for the first time at the molecular level that the o-NO2 group contributes less co

261 mulations approaches to characterize, at the molecular level, the antioxidant capacity of 5-HT and it

262 On the molecular level, the catalytic performance is further en

263 Finally, at a molecular level, the expression of synapsin genes SYN1 a

264 At a molecular level, the interaction of MDFIC with GR altere

265 At the molecular level, the sites of abnormal oral adhesions ma

266 models to better define, at the cellular and molecular level, the underlying mechanisms between BBB b

267 At the molecular level, there is a need to better understand st

268 At the molecular level, these changes are associated with incre

269 d by visualizing and recording events at the molecular level, this is still possible only in especial

270 to probe protein-nanoparticle binding at the molecular level, this work reveals one of nature's strat

271 g the effects of HIU on whey proteins on the molecular level, thus moving further toward implementing

272 ses information on pathogen variation at the molecular level to gain insights into a pathogen's niche

273 ow that polycystins and TAZ integrate at the molecular level to reciprocally regulate osteoblast and

274 s integrate extracellular information at the molecular level to regulate YAP1's nuclear localization

275 ndividual nanoparticles in cells at nano and molecular levels to establish their safety.

276 e ability to characterise variability at the molecular level, to apply mathematical models to the int

277 At the molecular level, transcription of the adherens junction

278 Here, we reveal the molecular-level underpinnings that distinguish an active

279 vitro anticancer activity, which defines the molecular level understanding and regions of structure-a

280 Molecular level understanding of electrode-mediated proc

281 Here we present a molecular level understanding of the initial target memb

282 eutics against these bacteria necessitates a molecular level understanding of the structure-dynamics-

283 e [B12X12](2-) MCAs provides the basis for a molecular level understanding of their observed unique p

284 ehicles, focusing on inconsistencies between molecular-level understanding and regional observations.

285 rface complexation is limited by the lack of molecular-level understanding of As-water-mineral intera

286 An atomic- and molecular-level understanding of heterogeneous catalysis

287 e to the central role of this cluster in the molecular-level understanding of hydrogen bonding in wat

288 structure is therefore important to obtain a molecular-level understanding of protein functions and t

289 ffective treatments for HCC will depend on a molecular-level understanding of the specific pathways d

290 Precatalyst 4 was characterized at the molecular level using advanced surface organometallic ch

291 action kinetics and thermodynamics at single molecular level using DNA as a probe.

292 Our study provides a molecular-level view of the first reported cyclopropane

293 At molecular level we provide evidence for non-canonical mo

294 role of SVP2 in kiwifruit development at the molecular level, we analysed the genome-wide direct targ

295 At the molecular level, we found a significant reduction in the

296 At the molecular level, we found that these disruptive effects

297 determine the impact of CAG expansion at the molecular level, we have developed novel allele-specific

298 On a molecular level, we observed a significant increase in t

299 port for this phylogenetic hypothesis at the molecular level, we sequenced the genomes of four cacti

300 types of bonds and forces them to mix on the molecular level without cosolvents.