ライフサイエンスコーパス: molecular machinery

1 s, is an integral component of the circadian molecular machinery.

2 ell understood, including its efficiency and molecular machinery.

3 rtaken, highlighting new elements in the PCD molecular machinery.

4 ent scaling up and scaling down use distinct molecular machinery.

5 as the lethal hit of CTLs but with distinct molecular machinery.

6 g elaborate and only partially characterized molecular machinery.

7 ythmicity and may be controlled by different molecular machinery.

8 understanding cellular perturbation and its molecular machinery.

9 factors such as RanBP1, employs NES-mediated molecular machinery.

10 sence of agonist may be mediated by distinct molecular machinery.

11 y but differ significantly in the underlying molecular machinery.

12 t active zones are orchestrated by a complex molecular machinery.

13 ncy require precise coordination of a cell's molecular machinery.

14 Cell division depends on sophisticated molecular machinery.

15 he directionality observed in RNA-processing molecular machineries.

16 gene transcripts in relation to interacting molecular machineries.

17 a stepwise process that coordinates multiple molecular machineries.

18 ant cells have developed specific protective molecular machinery against environmental stresses.

19 Consequently, elaborate molecular machineries and mechanisms emerged during the

20 e mediated by distinct pre- and postsynaptic molecular machineries and to have a specialized role in

21 ts cognate ligands are processed by the same molecular machinery and may antagonistically regulate ea

22 pruning share components of their underlying molecular machinery and may thus represent two developme

23 We find that despite very different molecular machinery and modes of action (catalytic vs st

24 ment is particularly important in autonomous molecular machinery and molecular computation, in which

25 Commonalities in molecular machinery and processes across FraX and Willia

26 h recent emphasis given to understanding its molecular machinery and regulation.

27 perties, our understanding of the underlying molecular machinery and signalling pathway in CB glomus

28 Gleason pattern 3 cells typically lack the molecular machinery and the genetic abnormalities, which

29 le back to the plasma membrane; however, the molecular machinery and trafficking pathways utilized by

30 contrasts in the phenotype, neurocircuitry, molecular machinery, and cellular processes in these two

31 cesses and functional similarities among its molecular machinery are apparent across all cellular lif

32 f predator-prey interactions on cellular and molecular machinery are poorly understood.

33 nts, apg and aut, have begun to identify the molecular machinery as well as indicate a substantial ov

34 enable analyses of where and when different molecular machineries associate with and act on the BR p

35 Instead, copper selectively up-regulates molecular machinery associated with the cell cycle and c

36 The molecular machinery at the nexus of apoptosis and inflam

37 e summarize the current understanding of the molecular machineries behind each of these types of auto

38 ll-induced platelet secretion (TCIPS) or the molecular machinery by which effector molecules are rele

39 ession and reveal additional features of the molecular machinery by which photoreceptors mediate phot

40 How the same molecular machinery can elicit such specific and distinc

41 We demonstrate that the essential molecular machinery can, in theory, fit into 0.06 microm

42 in aggregates can be resolved or degraded by molecular machinery conserved from bacteria to eukaryote

43 Thus, a common molecular machinery contributes to the nuclear maturatio

44 e data link cell surface Ret activation with molecular machinery controlling cytoskeletal dynamics an

45 tion, providing fundamental insight into the molecular machinery controlling ER and plasma membrane c

46 signaling may regulate internalization, the molecular machinery coordinating these two processes rem

47 o this crucial process, we have analyzed the molecular machinery directing polarized transport of RNA

48 chondrial apoptogenic proteins, although the molecular machinery downstream of JNK has not been preci

49 Many components of the molecular machinery driving cellularisation have been id

50 Thus, the cellular and molecular machinery driving hepatic functions is of utmo

51 There are two molecular machineries for pre-mRNA splicing-the major sp

52 cently, advances in our understanding of the molecular machineries for several gliding bacteria revea

53 e-dependently and coordinately regulates the molecular machinery for 2-AG signaling via tropomyosine

54 Thus the cER network serves to organize the molecular machinery for both insertion and removal of ce

55 several key elements of the currently known molecular machinery for endocannabinoid synthesis are th

56 These vesicles contained the molecular machinery for endocytosis and transcytosis.

57 Whereas the molecular machinery for exocytosis in presynaptic termin

58 We conclude that the molecular machinery for generating characteristic interc

59 The molecular machinery for kinase activation, therefore, is

60 The T domain therefore contains the entire molecular machinery for mediating transfer of the cataly

61 (SNAP receptors) are elements of a conserved molecular machinery for membrane targeting/fusion that h

62 Many of these synapses contain the molecular machinery for messenger RNA translation, sugge

63 Much of the molecular machinery for motility evolved in early eukary

64 a also contain SAMs expressing the analogous molecular machinery for NE clearance, which thus constit

65 the downregulation of key components of the molecular machinery for necroptosis.

66 ized primarily in the cell body, whereas the molecular machinery for neurite extension and elaboratio

67 communication in the brain, require complex molecular machinery for neurotransmitter release and rec

68 ve capacities, but in lower vertebrates, the molecular machinery for regeneration is an elemental par

69 at twinfilin can be an essential part of the molecular machinery for regulating filament lengths afte

70 pendent polymerase activity and provides the molecular machinery for RNA packaging.

71 ic sites on the membrane that have clustered molecular machinery for secretion [15], organized in par

72 Nature provides highly evolved, finely tuned molecular machinery for solar energy conversion that exq

73 Because complexins bind to the molecular machinery for synaptic vesicle fusion (the SNA

74 However, the molecular machinery for the production of oxygenated pol

75 Toward determining whether the molecular machinery for vesicular transmitter release is

76 We are learning to build synthetic molecular machinery from DNA.

77 spite similar fundamental organizations, the molecular machinery, functions, and evolutionary charact

78 tors of subtype 5 (mGluR5) contribute to the molecular machinery governing sleep-wake homeostasis.

79 comparatively little is known regarding the molecular machinery governing this process.

80 te these diverse functions, and an extensive molecular machinery has developed to support the assembl

81 This molecular machinery, however, is suspected to be a sourc

82 n, we show that in vivo manipulation of this molecular machinery in mice results in cardiomyocyte ded

83 y, these data provide insights into the SSBR molecular machinery in the cell and point to the involve

84 dinary capacity of HIV to exploit the cell's molecular machinery in the course of infection.

85 many hundreds of proteins that assemble into molecular machinery in the host cell that permit protein

86 increase in the complexity of the apoptotic molecular machinery in vertebrates, in terms of both the

87 ides an optimal system for understanding the molecular machineries involved in blood progenitor commi

88 y post-genomic era is the description of the molecular machineries involved in these processes.

89 define the transcriptional program encoding molecular machinery involved in alpha-synuclein patholog

90 dy represents a major step in unraveling the molecular machinery involved in anaerobic NO(3)(-) and N

91 s recognized role in enamel development, the molecular machinery involved in Ca2+ homeostasis in amel

92 ancer therapy, a better understanding of the molecular machinery involved in chemotherapy-related sen

93 Here we show that part of the molecular machinery involved in ciliogenesis also partic

94 This report demonstrates conservation of the molecular machinery involved in erythrocyte invasion by

95 The molecular machinery involved in establishing and maintai

96 The molecular machinery involved in GLUT4 vesicle tethering

97 However, the trafficking molecular machinery involved in lysosome exocytosis and

98 However, the molecular machinery involved in regulating caveolar upta

99 ating the plasma membrane recruitment of the molecular machinery involved in Rim101 processing and ac

100 s important to identify and characterize the molecular machinery involved in the assembly and mainten

101 n mutants, is beginning to shed light on the molecular machinery involved in the biogenesis of lysoso

102 In this Review, we discuss the molecular machinery involved in the generation of new ne

103 gested that LMO4 was an integral part of the molecular machinery involved in the negative regulation

104 he past decade has seen understanding of the molecular machinery involved in the pathogenesis of gene

105 However, the signals and the molecular machinery involved in the redox-dependent regu

106 spindle, although little is known about the molecular machinery involved in this process.

107 ome provides clues to the mechanisms of, and molecular machinery involved in, mitochondrial DNA inher

108 aining embryonic stem cell pluripotency, the molecular machinery involved remains poorly understood.

109 transport rather than directly affecting the molecular machinery involved.

110 Therefore, defining the dynamics of such molecular machinery is critical for understanding cell-s

111 tributed to the inappropriate acquisition of molecular machinery leading to metastatic transformation

112 e a crucial role in conferring dynamicity to molecular machineries like nucleic acid packaging motors

113 however, little is know about the underlying molecular machinery linking these two cytoskeletal syste

114 Here, we report synthetic molecular machinery made from DNA that controls and reco

115 The signals and the molecular machinery mediating release of dense matrix gr

116 , and/or, when possible, to have induced the molecular machinery mediating such effects to rely oppor

117 ed by GLUT4 translocation in muscle, but the molecular machinery mediating this process is poorly und

118 s demonstrate that TI cells not only contain molecular machinery necessary for active ion transport,

119 his was associated with the induction of the molecular machinery necessary for PC formation.

120 damental step in the quest to understand the molecular machinery of a cell.

121 rch aimed at understanding and improving the molecular machinery of Agrobacterium responsible for the

122 in complex multicellular organisms, the core molecular machinery of autophagy - the 'autophagy protei

123 we summarize our current knowledge about the molecular machinery of autophagy and the role of the aut

124 Stim and Orai proteins comprise the molecular machinery of Ca(2+) release-activated Ca(2+) (

125 detailed physiological observations with the molecular machinery of Ca(2+)-triggered exocytosis.

126 The molecular machinery of cell cycle control is known in mo

127 and worms continue to dissect the intricate molecular machinery of chemical synapses.

128 from shedding considerable new light on the molecular machinery of DNA replication in the archaea, t

129 efore the first unequivocal link between the molecular machinery of Drosophila cell death and the con

130 SNARE proteins are the conserved molecular machinery of exocytosis in the majority of sec

131 substantiated information on the specialized molecular machinery of gametocytogenesis and expedited t

132 cal and genetic analyses have determined the molecular machinery of IFT, but these studies do not exp

133 ta is an important step in understanding the molecular machinery of life.

134 ets coated with Atg8/LC3, a component of the molecular machinery of macroautophagy, and maintains pha

135 taste, relatively little is known about the molecular machinery of mechanosensation.

136 tein receptor (SNARE) complexes are the core molecular machinery of membrane fusion, a fundamental pr

137 Recent evidence suggests that the molecular machinery of RNA interference may function as

138 onventional synapses by interacting with the molecular machinery of synaptic vesicle fusion at the ac

139 To systematically characterize the molecular machinery of the adipocyte that mediates the r

140 to explain both relatively simple modules of molecular machinery of the cell and to achieve system-le

141 that has been made in understanding how the molecular machinery of the cell cycle is used in the pro

142 nscripts is dramatic evidence of the unusual molecular machinery of the early diverging protist G.lam

143 ding of the organization, communication, and molecular machinery of the liver.

144 A promising donor organism for the molecular machinery of this mechanism is the eukaryotic

145 checkpoint complex, an essential part of the molecular machinery on which the SAC relies.

146 ets of genes is limited, and the cooperating molecular machinery or specific genomic anchoring sequen

147 est that the cuticulosome and the associated molecular machinery regulate the concentration of iron w

148 our findings deepen our understanding of the molecular machinery regulating endocytosis and subsequen

149 Recent studies have begun to describe the molecular machinery regulating hypha orientation.

150 uestered before degradation, to identify the molecular machinery regulating sequestration, and to ana

151 The molecular machinery regulating these cell death programs

152 by ligands has been studied extensively, the molecular machinery regulating TRPA1 is only poorly unde

153 Consistent with this, the molecular machineries required for establishing segmenta

154 However, the molecular machinery required and possible trafficking ro

155 ated in this process, the composition of the molecular machinery required for efficient directional t

156 Here, we define the minimal molecular machinery required for FGF2 membrane transloca

157 P), is an essential feature of the conserved molecular machinery required for gliding motility and ce

158 blish PRMT8 as an important component of the molecular machinery required for hippocampal neuronal fu

159 With the molecular machinery required for mediating rapid flow-in

160 , confirming that these enterocytes have the molecular machinery required for phagocytosis.

161 In an effort to define the precise molecular machinery required for platelet exocytosis, we

162 mice, and may help to better understand the molecular machinery required for rabies virus spread in

163 These results indicate that the molecular machinery required for the assembly of the mit

164 Thus, subplate neurons regulate molecular machinery required to establish an adult balan

165 ol cell direction have been established, the molecular machinery required to generate the force of th

166 The molecular machinery responsible for apolipoprotein B RNA

167 In recent years, the molecular machinery responsible for apoptosis has been e

168 vided new insights into the structure of the molecular machinery responsible for biological oxygen pr

169 The molecular machinery responsible for DNA expression, reco

170 The molecular machinery responsible for DNA replication, the

171 ntly over the past two decades; however, the molecular machinery responsible for driving the system r

172 cades of research have uncovered much of the molecular machinery responsible for establishing and mai

173 at the heart of the RNA interference (RNAi) molecular machinery responsible for gene silencing.

174 The molecular machinery responsible for myonuclear positioni

175 uman cDNA encoding the mammalian enzyme, the molecular machinery responsible for regulating this acti

176 Recent studies have unveiled the molecular machinery responsible for the biological clock

177 agation of spreading depolarization, but the molecular machinery responsible for the dendritic beadin

178 c manipulations are beginning to unravel the molecular machinery responsible for the storage of fear

179 nrecognized link between neuronal NO and the molecular machinery responsible for the sustained synapt

180 Our evolving understanding of the molecular machinery responsible for the tightly controll

181 TCDD exposure suggest a direct effect on the molecular machinery responsible for these rhythms.

182 Little is known about the molecular machinery responsible for vesicle docking and

183 rs at a similar rate, suggests that the same molecular machinery serves to partition and place many,

184 The molecular machinery synapses use to convey information f

185 findings provide the first insight into the molecular machinery targeted by Rap signaling to modulat

186 Yet the molecular machineries that allow each cell to merge info

187 er, and the mouse have not only revealed the molecular machineries that cause the programmed demise o

188 ll surface proteins is mediated by a complex molecular machinery that assembles on the inner surface

189 Overall, water flow is detected by molecular machinery that can vary between hair cells of

190 Until recently, however, the molecular machinery that carries out reversible palmitoy

191 The molecular machinery that carries out the specific target

192 We describe the molecular machinery that co-ordinates gene transcription

193 a more detailed investigation of the complex molecular machinery that co-ordinates proliferation and

194 Although much is understood about the molecular machinery that confers HIF responsiveness to o

195 Little is known about the molecular machinery that contributes to site-specific co

196 mic study revealed candidate proteins of the molecular machinery that control the Golgi disassembly a

197 However, the molecular machinery that controls active transport of re

198 nstrate how these proteins interact with the molecular machinery that controls and executes the cell-

199 s, the discovery and characterization of the molecular machinery that controls cellular polarization

200 eristic that can be regulated by the complex molecular machinery that controls gene expression.

201 However, the molecular machinery that controls Ras ubiquitination has

202 The molecular machinery that controls secondary necrosis sta

203 lays a foundation for future studies on the molecular machinery that controls the development of the

204 However, little is known about the molecular machinery that controls the homeostasis of int

205 Our data reveal a molecular machinery that controls the photoperiodic regu

206 oroplast movement is beginning to define the molecular machinery that controls these movements.

207 s or Ab-secreting plasma cells; however, the molecular machinery that controls this cellular fate is

208 The molecular machinery that controls this massive export pr

209 pends crucially on microtubule dynamics, the molecular machinery that couples SGs to microtubule-depe

210 To identify the molecular machinery that defines Muller glial cell ident

211 However, the molecular machinery that determines the type of PCD is p

212 organs, relatively little is known about the molecular machinery that directly governs metabolic plas

213 The molecular machinery that directs formation of definitive

214 t extension relies on the same intracellular molecular machinery that directs planar cell polarity (P

215 To define the molecular machinery that directs repair, we applied lase

216 ies have provided a glimpse of the conserved molecular machinery that directs the localization of spe

217 ntified "embryonic" genes may be part of the molecular machinery that drives this unique growth pheno

218 trate that LOXL2 is a novel component of the molecular machinery that forms cross-linked collagen IV

219 Here, we focused on characterizing the molecular machinery that functions in the sequential syn

220 The answers lie in the molecular machinery that generates neural crest cells, c

221 ences in transcriptional programming and the molecular machinery that governs the migration, adhesion

222 onal molecular beacon for the recruitment of molecular machinery that imposes silencing across a chro

223 The molecular machinery that is involved in the entry and su

224 we present studies aimed at elucidating the molecular machinery that is responsible for the HG-induc

225 e that these new SR-TT junctions contain the molecular machinery that mediate SOCE: stromal interacti

226 suggesting a significant overlap between the molecular machinery that mediates DNA DSB repair, V(D)J

227 The molecular machinery that mediates sperm-egg interactions

228 leal tissue provides novel insights into the molecular machinery that mediates their functions and sp

229 The molecular machinery that mediates this organelle fission

230 ening in antigen receptor gene assembly, the molecular machinery that mediates this reaction has not

231 ittle is known about their biogenesis or the molecular machinery that modulates this process.

232 HSPA1A) and Hsp110 (HSPH1) formed a powerful molecular machinery that optimally reactivated stable lu

233 g in neurones, but little is known about the molecular machinery that orchestrates the process.The am

234 ies has shed light on the details of how the molecular machinery that orchestrates these attachments

235 The molecular machinery that organizes the signaling molecul

236 They also indicate that the molecular machinery that promotes the wrapping of the gl

237 have proven instrumental for unraveling the molecular machinery that regulates actin polymerization.

238 l cell types, the Par complex is part of the molecular machinery that regulates cell polarity and mai

239 We propose that DBC1 is part of the molecular machinery that regulates fat storage capacity

240 er, little is known regarding the underlying molecular machinery that regulates its stability.

241 The molecular machinery that regulates the entry and surviva

242 eletal structure that act by subjugating the molecular machinery that regulates the G1/S transition.

243 rized type of adult stem cell, the intricate molecular machinery that regulates their self-renewal pr

244 Currently, the molecular machinery that regulates this sorting pathway

245 The molecular machinery that shapes the endoplasmic reticulu

246 anchorage to the cytoskeleton; however, the molecular machinery that supports this process remains e

247 s of the gamma-secretase core complex with a molecular machinery that targets and fuses synaptic vesi

248 een described, little is known regarding the molecular machinery that terminates Arc function.

249 PM, indicating that it is a component of the molecular machinery that tether SGs to the PM.

250 Over the past two decades, the molecular machinery that underlies autophagic responses

251 plex is important for the elucidation of the molecular machinery that underlies synaptic transmission

252 cription of the cell from the perspective of molecular machinery (the mechanome) is likely to emerge

253 Furthermore, a unique molecular machinery, the editosome, catalyzes the proces

254 e codon usage in the context of their host's molecular machinery, their genomes provide another windo

255 ation and illustrates the different usage of molecular machineries to accomplish the same biological

256 ssible to relate the dynamic organization of molecular machinery to cellular function.

257 and the OS share common building blocks and molecular machinery to construct and maintain them.

258 lymphomagenesis by subverting the host-cell molecular machinery to deregulate cell growth and surviv

259 her way in which the virus exploits the host molecular machinery to expand its limited genetic repert

260 How ZIKV interacts with the host molecular machinery to impact neurogenesis in vivo is no

261 dysregulating neutrophil gene expression and molecular machinery to potentially maximize its survival

262 strates that self-renewing mESCs possess the molecular machinery to sense shear stress and provides q

263 s flow-sensing organelles with the necessary molecular machinery to transduce rapidly, mechanical sti

264 ization, domestication, as well as about the molecular machineries underlying them.

265 Together, our data suggest that the molecular machinery underlying axonal insulation and axo

266 d to reveal further important aspects of the molecular machinery underlying lineage commitment.

267 sease is therefore crucial to dissecting the molecular machinery underlying LSC self-renewal.

268 Because the molecular machinery underlying LTS is common to many cel

269 In the quest to identify the molecular machinery underlying mechanoelectrical transdu

270 Integrating these findings with the molecular machinery underlying migration will provide a

271 However, the molecular machinery underlying MT dynamics in tip-growin

272 The molecular machinery underlying neurotransmitter receptor

273 Akinduro et al. detail the molecular machinery underlying removal of the nucleus (n

274 Overall, our analysis sheds light on the molecular machinery underlying subunit communication, an

275 havior, yet there is much to learn about the molecular machinery underlying the coordination between

276 nome have generally been hypothesized as the molecular machinery underlying the persistent, often tis

277 To gain a better understanding of the molecular machinery underlying the pleiotropic functions

278 However, the molecular machinery underlying these hierarchically thre

279 nologic tolerance, little is known about the molecular machinery underlying this process.

280 velopmental processes in plants, the broader molecular machinery underpinning polarity establishment

281 Furthermore, the molecular machinery used by normal stem cells for homing

282 spindle and broaden our understanding of the molecular machinery used to move chromosomes.

283 nto diverse mammalian cells by hijacking the molecular machinery used to organize cellular membranes.

284 ings should prove useful for elucidating the molecular machinery used to transmit a signal into a vir

285 Thus, the molecular machinery utilized by bladder epithelial cells

286 e than three billion years, during which its molecular machinery was perfected to minimize wasteful r

287 rom the fields of molecular conductivity and molecular machinery we set out to design a crystalline m

288 study multi-protein interactions within such molecular machineries, we have developed a fluorescence

289 : (i) that the rods, and their corresponding molecular machinery, were lost or (ii) that the rods wer

290 d accurate means to describe the dynamics of molecular machinery which orchestrates gene regulation.

291 that these cells share elements of a common molecular machinery with stem cells in other tissues.

292 whether the interval-timing mechanism shares molecular machinery with the circadian timing mechanism.

293 While we know much about the molecular machinery within each compartment, we are only

294 NA and RNA polymerases with their associated molecular machinery would move along the DNA template wi