ライフサイエンスコーパス: molecular recognition

1 the interior that strongly influenced their molecular recognition.

2 mus (supra-tauc window), strongly influence molecular recognition.

3 of foldamers to outstanding achievements in molecular recognition.

4 link of the observed supra-tauc motion with molecular recognition.

5 formational selection and/or induced fit) of molecular recognition.

6 ly used in protein/ligand design to modulate molecular recognition.

7 e of individual conductance measurements for molecular recognition.

8 he key role of these residues in the peptide molecular recognition.

9 nal selection is an established mechanism in molecular recognition.

10 n bonds play an essential role in biological molecular recognition.

11 teins are proteins that maintain promiscuous molecular recognition.

12 static fields, which play a critical role in molecular recognition.

13 olecular imprinting technique depends on the molecular recognition.

14 olymeric macromolecules capable of exquisite molecular recognition.

15 s as a directional (poly)anion that exhibits molecular recognition.

16 the function of antifreeze proteins and for molecular recognition.

17 ulating new approaches to the application of molecular recognition.

18 of the physiochemical principles that govern molecular recognition.

19 tate reduces the problem of design to one of molecular recognition.

20 functional groups in enzymatic catalysis and molecular recognition.

21 important in providing an efficient mode of molecular recognition.

22 d transmission within the broad framework of molecular recognition.

23 considered as hydrogen bond donor groups in molecular recognition.

24 eral hundred Hertz, which typically prevents molecular recognition.

25 has the potential to be used for signalling molecular recognition.

26 ctors for transition-state stabilization and molecular recognition.

27 epigenetic marks and challenging targets for molecular recognition.

28 ydrogen bonds are ubiquitous interactions in molecular recognition.

29 natives to bio-receptors due to the inherent molecular recognition abilities and the high stability i

30 NMR magnetization transfer sequences and the molecular recognition abilities of nanoparticles allows

31 n their structural features as well as their molecular recognition abilities.

32 specific "ligand" molecule in order to gain molecular recognition ability.

33 Molecular recognition, activation and dynamic self-assem

34 Nucleic acid aptamers are versatile molecular recognition agents that bind to their targets

35 for discovery of sulfide protein targets and molecular recognition agents.

36 e analysis shows that although high-affinity molecular recognition allows robust detection of the flu

37 must possess both the capacity for specific molecular recognition and a dynamic nature to their intr

38 d by the unique combination of peptide-based molecular recognition and a rhodium catalyst capable of

39 action to the ubiquitous hydrogen bonding in molecular recognition and assembly.

40 at are capable of complex functions, such as molecular recognition and catalysis, is provided by sequ

41 ned three-dimensional structures that retain molecular recognition and catalytic properties and, ther

42 nd esters have been extensively utilized for molecular recognition and chemical sensing.

43 y adopting P or M helicity, is described for molecular recognition and chirality sensing.

44 yclic entities that display a combination of molecular recognition and complexation properties with v

45 cular entities that display a combination of molecular recognition and complexation properties with v

46 ignaling processes are primarily promoted by molecular recognition and corresponding protein-protein

47 Molecular recognition and discrimination of carbohydrate

48 c data for biological interactions including molecular recognition and enzymatic catalysis.

49 re will further our understanding of RNase P molecular recognition and facilitate discovery of antiba

50 oligomers are finding broad applications for molecular recognition and for inhibiting protein-protein

51 ps binding to BRCT to understand promiscuous molecular recognition and guide inhibitor design.

52 However, the thermodynamics governing the molecular recognition and interaction of lipids with mem

53 The molecular recognition and interactions governing site-sp

54 repeat proteins have been re-engineered for molecular recognition and modular scaffolding applicatio

55 limitations of exploiting halogen bonds for molecular recognition and rational drug design.

56 templates for nanomaterials due to inherent molecular recognition and self-assembly capabilities com

57 nd short range molecular interactions govern molecular recognition and self-assembly of biological ma

58 loid structures are formed by the process of molecular recognition and self-assembly, wherein a pepti

59 DNA has unique capabilities for molecular recognition and self-assembly, which have fost

60 modes that play key roles in a multitude of molecular recognition and signaling processes.

61 e stage for uncovering novel determinants of molecular recognition and signalling in single-spanning

62 ynergy of proteins, and consequently involve molecular recognition and spatial constraints between bi

63 for investigation of the combined effects of molecular recognition and spatial constraints in biomole

64 We incorporated a high degree of molecular recognition and specific design features makin

65 wing inspiration from pioneering research in molecular recognition and structural biology.

66 ion should be directly relative to issues of molecular recognition and supermolecular self-assembly.

67 actions in large part control guest binding, molecular recognition and the chemical reactivity of bou

68 o distinct areas of the protein that enhance molecular recognition and therefore could be used for th

69 derived binding handles is essential for the molecular recognition and transport process, allowing se

70 on due to their biocompatibility, functional molecular recognition and unique biological and electron

71 in which to achieve selective high-affinity molecular recognition, and as such, this system provides

72 bonds on protein and nucleic acid structure, molecular recognition, and enzyme catalysis and conclude

73 attractive functional targets for synthesis, molecular recognition, and hierarchical self-assembly.

74 roles including transcriptional regulation, molecular recognition, and provision of sites for posttr

75 ications including drug delivery, catalysis, molecular recognition, and sensing.

76 se results showcase the contextual nature of molecular recognition, and suggest further that nonnativ

77 l current interest, including self-assembly, molecular recognition, and supramolecular assembly.

78 lished tools of supramolecular chemistry and molecular recognition, and they are finding increasing a

79 ke the one presented herein are the basis of molecular recognition, and we expect this principle to f

80 This type of molecular recognition appears to enable dual specificity

81 of a library of functional hybrid solids for molecular recognition applications such as sensing, sepa

82 Important for molecular recognition applications, fluorescence quenchi

83 potentially deliver functional molecules for molecular recognition applications.

84 Using this molecular recognition approach, we identified an aptamer

85 c selectivity, size selectivity and targeted molecular recognition are attractive characteristics for

86 folding and misfolding, ligand binding, and molecular recognition are provided as a means of illustr

87 , but they lack the precise base pairing and molecular recognition available with nucleic acid assemb

88 trate the remarkable selectivity afforded by molecular recognition based on alkadiyne side chain shap

89 Herein, we demonstrate how the energy of the molecular recognition between a supramolecular host and

90 sect the molecular mechanism, we examine the molecular recognition between AFP and trehalose crystal

91 lphaLeu285 residues, an essential region for molecular recognition between alpha-alpha and beta-beta

92 l(4), we hypothesize that a perfect match in molecular recognition between alpha-cyclodextrin and [Au

93 lymer was constructed in water by host-guest molecular recognition between bis(p-sulfonatocalix[4]are

94 Molecular recognition between cells is thus a fundamenta

95 otein surface and provides the rationale for molecular recognition between monoFc and FcRn.

96 ]pseudorotaxane employing radically enhanced molecular recognition between the bisradical dication ob

97 it intein chemistry is preceded by efficient molecular recognition between two protomers that become

98 such as concanavalin A (Con A) based on the molecular recognitions between the glycan ligands on the

99 Molecular recognition, binding and catalysis are often m

100 place at lipid membrane surfaces, including molecular recognition, binding, and protein-protein inte

101 are deemed essential to enzymatic catalysis, molecular recognition, bioenergetic transduction, and at

102 ractions in proteins is key to understanding molecular recognition, biological functions, and is cent

103 are increasingly evoked in models of protein molecular recognition but are challenging to experimenta

104 The structural basis for molecular recognition by 2 classes of anti-C2 inhibitory

105 emonstrated herein adds to the repertoire of molecular recognition by AF(G)Ps, which may have potenti

106 a highly efficient and unusual mechanism of molecular recognition by an antibody.

107 kbone structure and the role of the sugar in molecular recognition by antibodies are emphasised.

108 l chemical interactions and is essential for molecular recognition by biological macromolecules.

109 ter infection in order to define the mode of molecular recognition by enhancing antibodies.

110 Molecular recognition by proteins is fundamental to mole

111 the general role of entropy in high-affinity molecular recognition by proteins.

112 ation would generate P450 phosphodegrons for molecular recognition by the E2-E3 complexes, thereby co

113 Information in the process of molecular recognition can be transmitted to us via physi

114 iner precursors, are known for their tunable molecular recognition capabilities towards an array of g

115 to prepare biocompatible UCNPs with specific molecular recognition capabilities.

116 imprinted polymers (MIPs) have a predesigned molecular recognition capability that can be used to bui

117 MFC is partially replaced by an ionomer with molecular recognition capability working as the biorecog

118 Nano-molecularly imprinted polymer with molecular recognition capacity was made-up by using SiO2

119 Integrating molecular recognition, catalysis, and assembly, these ac

120 ng of protein dynamics and their relation to molecular recognition, catalytic function, and allostery

121 Control experiments demonstrated the molecular recognition characteristic inferred by the enz

122 The allosteric RNAs display molecular recognition characteristics that mimic the hig

123 rganization and predisposition are important molecular recognition concepts exploited by nature to ob

124 lymers, foldamers, supramolecular materials, molecular recognition, conductive and opto-electronic ma

125 Specific binding between biomolecules, i.e., molecular recognition, controls virtually all biological

126 Corona phase molecular recognition (CoPhMoRe) uses a heteropolymer ad

127 rk, we applied a new technique, corona phase molecular recognition (CoPhMoRe), to identify adsorbed p

128 e well-defined structure supports a model of molecular recognition dominated by conformational select

129 mediate many biological functions, including molecular recognition during development, immune respons

130 A molecular recognition element (MoRE) domain mediates bin

131 sibility of using aptamers as an alternative molecular recognition element in ELISA.

132 ported to have affinity for human OPN as the molecular recognition element, and the ferro/ferricyanid

133 First, GOx, as a molecular recognition element, catalyzes the oxidation o

134 cterized through the immobilization of their molecular recognition elements (MREs) onto gold disk ele

135 amers have been reported as highly versatile molecular recognition elements for biosensor development

136 ests a possible role for these structures as molecular recognition elements for p15(PAF).

137 Aptamers have exhibited many advantages as molecular recognition elements for sensing devices compa

138 rgize the properties of both transducers and molecular recognition elements improving the performance

139 ctional and robust porous materials serve as molecular recognition elements that can be used to captu

140 ferent strategies and highlights the leading molecular recognition elements that have potential roles

141 e corresponding split/integrated aptamers as molecular recognition elements, and gold nanoparticles a

142 lysozyme cavities speak to the subtleties of molecular recognition even in these simple sites and to

143 actions provides insights into the nature of molecular recognition events and has practical uses in g

144 nding affinity and kinetic rate constants of molecular recognition events calculated for NNV-AMP(TH1-

145 or absorption largely overlaps the signal of molecular recognition events in the visible spectrum, ma

146 ions to provide signal amplification so that molecular recognition events indicative of disease state

147 ate important roles for dispersion forces in molecular recognition events should be interpreted with

148 However, little is known about the molecular recognition events that mediate phage adsorpti

149 y is uniquely suited for detecting transient molecular recognition events, yet achieving the time res

150 on of synergistic or antagonistic effects to molecular recognition events.

151 a conditional manner to detect and quantify molecular recognition events.

152 he proper presentation of the sugar unit for molecular recognition events.

153 -to-order mutations also influence predicted molecular recognition features (MoRFs) more often than t

154 action-prone protein IDPRs are identified as molecular recognition features (MoRFs).

155 ions, conserved eukaryotic linear motifs and molecular recognition features present in the C-tail IDR

156 teraction-prone segments within IDPs, termed molecular recognition features, represent potential bind

157 lts advance the mechanistic understanding of molecular recognition for a major class of splice site s

158 the flexibility and rigidity, and the unique molecular recognition for silicic acid, followed by the

159 The observed molecular recognition fundamentally differs from canonic

160 e contribution of sequence diversity to this molecular recognition has been studied for decades, rece

161 ious parameters, including biocompatibility, molecular recognition, high fluorescence quantum efficie

162 e.g., protein misfolding, electron transfer, molecular recognition); however, few tools exist for mea

163 Thus, molecular recognition in binding and activation processe

164 serve as excellent models for understanding molecular recognition in biomineralization.

165 y, may thus be a dominating factor in chiral molecular recognition in such systems.

166 ger PAHs, the Rebek 55% solution formula for molecular recognition in the liquid state becomes less a

167 onally connected pore network, which enables molecular recognition in the size range 0.5-0.6 nm.

168 for technical improvements, including use of molecular recognition, in selective metal separation tec

169 cial replicators have been designed based on molecular recognition, inspired by the template copying

170 The molecular recognition interaction between the peptide (p

171 ules bound to all PNTs polymers due to their molecular recognition interaction involving histidines a

172 nfluenced by a cooperative topology based on molecular recognition interactions with Cu(2+)-trisNTA b

173 zymes, positively selected residues point to molecular recognition interfaces between host and viral

174 nate peptide with a component of induced fit molecular recognition involving the adoption of multiple

175 Molecular recognition is an important initial step for t

176 It is shown that molecular recognition is based on cooperative hydrogen b

177 Although molecular recognition is crucial for cellular signaling,

178 Understanding molecular recognition is of fundamental importance in ap

179 icates that for these proteins a key role in molecular recognition is played by disordered regions ch

180 This type of broad molecular recognition is possible because the electronic

181 assembly in water by non-covalent host-guest molecular recognition is sufficiently strong to form the

182 The process of molecular recognition is the assembly of two or more mol

183 This degree of specificity in collagen molecular recognition is unprecedented in natural or syn

184 Such molecular recognition lessons are important for engineer

185 fluorine often plays an influential role in molecular recognition, little is known about the effect

186 The dense distribution of molecular recognition loops on the robust peptoid nanosh

187 mutations to occur, and stringent DNA groove molecular recognition may be required to maintain intrin

188 Together, our data reveal differences in the molecular recognition mechanisms associated with evoluti

189 playing important roles throughout biology, molecular recognition mechanisms in intrinsically disord

190 results shine new light onto stereoselective molecular recognition mediated by van der Waals forces.

191 t can transform into polymer films through a molecular recognition-mediated crosslinking process.

192 ades and highlights emerging applications in molecular recognition, medicinal chemistry and catalysis

193 Many molecular recognition methods target ribosomal RNA seque

194 However, their specific molecular recognition motif (terephthalamide-bisurea) fa

195 tential method to "wrap" surfaces displaying molecular recognition motifs-which could potentially inc

196 talysis, deracemisation and discovery of new molecular recognition motifs.

197 ng highly deformable microgel particles with molecular-recognition motifs identified through directed

198 Although the reaction kinetics and molecular recognition of a few individual model substrat

199 Accordingly, we faced the molecular recognition of a target dipeptide (Ac-EY-OH) m

200 aniline and phenylhydrazine dyes that enable molecular recognition of a wide variety of aliphatic or

201 scanned as chiral solvating agents to study molecular recognition of acids by NMR analysis.

202 A and establish the structural basis for the molecular recognition of adenosine ribonucleotides.

203 aphosphonate resorcinarene cavitands for the molecular recognition of amino acids.

204 structure allows us to explore in detail the molecular recognition of antagonists.

205 Many factors govern molecular recognition of biological targets by small mol

206 knowledge has enlightened research into the molecular recognition of biologically active molecules,

207 odeling procedures, we have investigated the molecular recognition of C8-substituted-nucleotides by F

208 Molecular recognition of carbohydrates plays an importan

209 Molecular recognition of carbohydrates plays vital roles

210 lar-dynamics simulations, to investigate the molecular recognition of CXCR4 by a dual tropic V3 loop.

211 Thus, elucidating the molecular recognition of CXCR4 by the V3 loop is importa

212 The molecular recognition of CXCR4 or CCR5 by the HIV-1 gp12

213 First, we performed a molecular recognition of DCL- and AG-PEGylation on ligan

214 tion of antibody-toxin interactions based on molecular recognition of distinctive toxic motifs are el

215 These models were developed to explore molecular recognition of known epigenetic recognition mo

216 ing similar interactions are involved in the molecular recognition of MDM by the AF(G)Ps.

217 evel and provide chemical perspective on the molecular recognition of membrane receptors.

218 with miRNA expression regulators, exhibiting molecular recognition of miRNA profile changes.

219 evelop an oligonucleotide microarray for the molecular recognition of multiple plant components in co

220 Our approach relies on selective molecular recognition of one enantiomer of the target mo

221 high binding affinity and thus provides for molecular recognition of OTA; simulating the mycotoxin-s

222 ls and can offer deep understanding into the molecular recognition of pathogen-host receptor interact

223 hus this approach should also facilitate the molecular recognition of peptides.

224 in addition to sequence, is critical for the molecular recognition of RNA.

225 The molecular recognition of short peptides is a challenge i

226 hy, providing detailed information about the molecular recognition of small-molecule ligands binding

227 y and provide detailed information about the molecular recognition of small-molecule ligands binding

228 mesoporous support, protein selectivity, and molecular recognition of substrates).

229 or biomolecule deactivation, is crucial for molecular recognition of target molecules or cells.

230 pecific antibody functionalization, based on molecular recognition of the constant Fc region.

231 n current defined by tauopen, which includes molecular recognition of the incoming dNTP.

232 ds lanthanide and actinide complexes through molecular recognition of the ligands chelating the metal

233 Our findings provide further insight into molecular recognition of the major receptor on the HIV v

234 of glucagon bound to GCGR to understand the molecular recognition of the receptor for its native lig

235 n a protein IR spectrum, to characterize the molecular recognition of the Src homology 3 (SH3) domain

236 This paper describes the molecular recognition of the tripeptide Tyr-Leu-Ala by t

237 ented here provide crucial insights into the molecular recognition of the two cofactors, F420 and NAD

238 all has complicated the understanding of the molecular recognition of these antigens by antibodies pr

239 nding of the chemical and physical basis for molecular recognition of viral surface proteins in order

240 e cell surface glycosylation and the complex molecular recognition on the intact cell surface, which

241 uning hydrophobic driving forces to optimize molecular recognition or self-assembly processes.

242 properties that arise from self-assembly and molecular recognition phenomena are a direct consequence

243 zation effects in conformational control and molecular recognition phenomena.

244 of a SpA side chain by an Fc side chain in a molecular-recognition pocket.

245 Molecular recognition probes provide a new approach to q

246 ns are sensitive to solvation equilibria, so molecular recognition probes provide fundamentally diffe

247 e insights into the overall organization and molecular recognition process of the phage varphi11 tail

248 nteractions play important roles in numerous molecular recognition processes in chemistry and biology

249 As for a variety of other molecular recognition processes, conformational fluctuat

250 Examples include molecular recognition processes, which trigger biologica

251 ons are notoriously difficult to separate in molecular recognition processes.

252 nce of Ser and Thr O-glycosylation points in molecular recognition processes.

253 al ions and provide a framework for studying molecular recognition processes.

254 nal groups important in a wide assortment of molecular recognition processes.

255 biochemical cascade formed by the collective molecular recognition properties and proteolytic activit

256 g proteins and DNAs were based on the unique molecular recognition properties of HO to the targets to

257 Furthermore, the molecular recognition properties of T1R1-T1R3 guided tas

258 The molecular recognition properties of the nucleobases inst

259 porters while avoiding any impairment of the molecular recognition properties of the peptides.

260 ect of porogen on particle size and specific molecular recognition properties.

261 Molecular recognition reagents are key tools for underst

262 This remarkable example of specific molecular recognition requires a reduced dimensionality

263 ynthetic polymers for applications including molecular recognition, self-assembly, and catalysis.

264 mics, have drawn attention in the context of molecular recognition, self-assembly, and supramolecular

265 exes that are directly relevant to issues of molecular recognition, self-assembly, and supramolecular

266 all molecules in enantioselective catalysis, molecular recognition, self-assembly, material science,

267 espread in nature and have critical roles in molecular recognition, signalling, and other essential b

268 le oligomers, may allow the formation of new molecular recognition signals that guide aggregate targe

269 in allosteric signaling between promiscuous molecular recognition sites and can inform the rational

270 s unprecedented surface area, pore aperture, molecular recognition, stability, and catalysis, through

271 This novel molecular recognition strategy to trigger morphological

272 Molecular recognition studies with IAPP and Abeta1-42 em

273 The fundamental principles guiding the molecular recognition, such as self-assembly and complem

274 However, complex aspects of molecular recognition-such as protein flexibility or the

275 ic mechanism that may be utilized broadly by molecular recognition systems.

276 detection of cancer cells through important molecular recognition target such as sialic acid is sign

277 protein-ligand complexes provide details of molecular recognition that can be used to infer binding

278 Knowledge of the forces associated with the molecular recognition that governs Trx-protein interacti

279 ting the SH2 domain is a challenging task in molecular recognition, the progress reported here demons

280 Molecular recognition--the ability of a molecular machin

281 hydrophobic pocket exclusively via specific molecular recognition; the contact interface is dominate

282 substitution-inert complexes is achieved by molecular recognition through minor groove spanning and

283 d provide important functional advantages in molecular recognition through transient protein-protein

284 cribe the extension of radical-pairing-based molecular recognition to a larger, square-shaped diradic

285 d biomimetic transformations, and the use of molecular recognition to control reaction selectivity.

286 These events range from protein folding and molecular recognition to the formation of hierarchical s

287 synthetic chemistry, in conjunction with the molecular recognition toolkit pioneered by the field of

288 Past efforts to design repeat protein-based molecular recognition tools have focused on the creation

289 oth a calix[4]arene moiety which serves as a molecular recognition unit and an activity regulator com

290 se layer of polymer chains that terminate in molecular recognition units capable of programmed supram

291 ar polymerization by non-covalent host-guest molecular recognition was confirmed by (1)H NMR spectros

292 The ability for molecular recognition was evaluated with the well-known

293 s with the conformational selection model of molecular recognition, which assumes such pre-existing c

294 fic sandwich-type detection due to specific, molecular recognition, while unbound beads move along pa

295 However, molecular recognition with hexaphyrins has been underexp

296 results provide unprecedented insights into molecular recognition with hexaphyrins, paving the way t

297 how that rhodium(II) metallopeptides combine molecular recognition with promiscuous catalytic activit

298 The SCNPs utilise molecular recognition with surface-immobilised proteins

299 nt secondary structure are often involved in molecular recognition, with the structure being stabiliz

300 inear motifs) within these contacts underpin molecular recognition, yet have poor pharmacological pro