ライフサイエンスコーパス: molecular replacement

1 e been phased using external information via molecular replacement.

2 phate), is determined to 2.3 A resolution by molecular replacement.

3 ructure of H256A to a resolution of 2.4 A by molecular replacement.

4 hine has been solved at 1.85-A resolution by molecular replacement.

5 An x-ray structure was determined by molecular replacement.

6 roup P41212, and the structure was solved by molecular replacement.

7 he corresponding X-ray crystal structures by molecular replacement.

8 e has been determined to 2.5 A resolution by molecular replacement.

9 tfC crystal structure was solved at 2.7 A by molecular replacement.

10 ylated human IFN-beta at 2.2-A resolution by molecular replacement.

11 resolution, and the structure was solved by molecular replacement.

12 the RCs in the unit cell were determined by molecular replacement.

13 Triton X-100 and the structure was solved by molecular replacement.

14 structure was solved to 1.5-A resolution by molecular replacement.

15 enzyme in phenazine biosynthesis, solved by molecular replacement.

16 ) was also determined at 2.6 A resolution by molecular replacement.

17 lized at pH 6.25 and its structure solved by molecular replacement.

18 iously, it was possible to use the method of molecular replacement.

19 been determined to a resolution of 3.0 A by molecular replacement.

20 on-inhibited W197I variant was determined by molecular replacement (2.2 A); it revealed a stabilized

21 The structure was determined by molecular replacement, a recently determined structure o

22 The structure was solved using molecular replacement, aided by an isomorphous derivativ

23 xMDFF, either fails to produce a solution by molecular replacement alone or produces an inaccurate st

24 Serial crystallographic data for molecular replacement already converges in 1,000-10,000

25 pection of the X-ray diffraction pattern and molecular replacement analysis revealed the orientation

26 ex was solved at a resolution of 3.0 A using molecular replacement and constitutes the first reported

27 ex was solved at a resolution of 2.5 A using molecular replacement and constitutes the first reported

28 d to 2.1 A resolution using a combination of molecular replacement and isomorphous replacement and re

29 structure of TeNT-LC, determined by combined molecular replacement and MAD phasing.

30 ylate has been solved using a combination of molecular replacement and noncrystallographic symmetry a

31 A using X-ray diffraction analysis based on molecular replacement and phase extension methods.

32 A resolution and the structure determined by molecular replacement and phase extension.

33 The OIH-1 structure was solved by molecular replacement and refined at 1.25 A resolution.

34 The structure has been solved by molecular replacement and refined at 1.8 A resolution.

35 The structure was solved by molecular replacement and refined at 2.0 A resolution.

36 from Arabidopsis thaliana has been solved by molecular replacement and refined at the resolution of 1

37 noclonal antibody (Mab231) was determined by molecular replacement and refined in a triclinic cell to

38 The structures were solved by molecular replacement and refined to 2.1 (K+) and 2.35 A

39 =59.15 A, c=94.44 A) have been determined by molecular replacement and refined versus data to 2.0 A a

40 .9 A resolution; the structure was solved by molecular replacement and refined with an R-factor of 0.

41 Man-alpha 1,3-Man-OMe complex, determined by molecular replacement and refined with X-PLOR using NCS

42 Structure analysis by molecular replacement and refinement at 2.2A resolution

43 n fluorescent protein has been determined by molecular replacement and the model refined.

44 Molecular replacement and weak phasing information from

45 placed in the crystallographic unit cell by molecular replacement, and how initial phases computed f

46 The structures were determined by molecular replacement, and refined to 3.1 A (native) and

47 The SM3-MUC1 peptide structure was solved by molecular replacement, and the current model is refined

48 6 (lambda(em)max = 486 nm) was determined by molecular replacement, and the model was refined at 1.65

49 These crystalline properties permitted a molecular replacement approach based upon a beta-hairpin

50 We have now used a molecular replacement approach on an AMPAR-null backgrou

51 In this review, we discuss a single-cell molecular replacement approach which should arguably adv

52 ure of the variant protein was determined by molecular replacement as a T(3)R(3) zinc hexamer.

53 tadecyl-CoA, and its structure was solved by molecular replacement at 1.4 A resolution.

54 esidues Asp 2-Asn 762 has been determined by molecular replacement at 1.9 A resolution and refined to

55 europneumoniae, a major porcine pathogen, by molecular replacement at 1.9 A resolution.

56 d the crystal structures of AgaA and AgaB by molecular replacement at 3.2- and 1.8 A-resolution, resp

57 s cerevisiae chorismate mutase was solved by molecular replacement at a resolution of 2.8 angstroms u

58 ture determined to 4.4-A resolution by using molecular replacement based on the structure of the beef

59 beta motifs with an accuracy high enough for molecular replacement based phasing.

60 Knowledge-based databases holding molecular replacements can be supportive in the optimiza

61 inal Src kinase (CSK) has been determined by molecular replacement, co-complexed with the protein kin

62 Through the method of Wide Search Molecular Replacement, developed here, they can be compl

63 ended in steps to 3.0 angstrom resolution by molecular replacement electron density modification and

64 Molecular replacement experiments revealed that the LRRT

65 Molecular replacement experiments show that both Spindly

66 Finally, we employed molecular replacement experiments using a knockdown resc

67 Using in vivo molecular replacement experiments, we find that these un

68 m for structure determination of lysozyme by molecular replacement followed by crystallographic refin

69 itor, were determined at 2.0 A resolution by molecular replacement from a second crystal form and wer

70 native crystals in the space group P3(1), by molecular replacement from the 2.8 A model (1F88) solved

71 and in the absence of templates suitable for molecular replacement from the Protein Data Bank.

72 of the complex with Mg(2+)*OSB was solved by molecular replacement in space group P2(1)2(1)2.

73 tate at 2.03 A resolution that was solved by molecular replacement in the space group P6(5) with two

74 Molecular replacement in X-ray crystallography is the pr

75 tructures are determined using the method of molecular replacement, in which known related structures

76 l in phasing crystallographic data for which molecular replacement is hindered by the absence of suff

77 nderstanding of the signal-to-noise ratio in molecular replacement leads to the finding that, with da

78 The structure was solved by the molecular replacement method and refined at 1.7 A resolu

79 crystal structure of hCBG was solved by the molecular replacement method and refined at 2.7 A resolu

80 The structure was solved by the molecular replacement method and refined to a final R-fa

81 The structure was solved by the molecular replacement method and refined to an Rwork/Rfr

82 The structure was solved by the molecular replacement method and subsequently refined us

83 of IVD was solved at 2.6 A resolution by the molecular replacement method and was refined to an R-fac

84 The structure was solved by the molecular replacement method at 1.9 A resolution and ref

85 on method for the first crystal form and the molecular replacement method for the second crystal form

86 Both structures were solved by the molecular replacement method using different starting mo

87 initial solution was determined by using the molecular replacement method using the structure of the

88 otein or peptide can be determined using the molecular replacement method with the help of the GST st

89 The crystal structure was solved by the molecular replacement method, and the model has been ref

90 The structure was solved by the molecular replacement method, and the model has been ref

91 The molecular replacement method, starting with d(pGpC) of t

92 The molecular replacement method, with the NAP-2 tetramer as

93 The structures were solved by the molecular replacement method.

94 The structure was solved using the molecular replacement method.

95 id) complex were determined with the help of molecular replacement methods to 2.0A and 2.3A resolutio

96 bound to domain VI of calpain, determined by molecular replacement methods to 2.5A and 2.2A resolutio

97 tic domain joined by a linker, was solved by molecular replacement methods using independent search m

98 human plasminogen (K5HPg) has been solved by molecular replacement methods using K1HPg as a model and

99 ccus surface protein, has been determined by molecular replacement methods using K4Pg as a model, and

100 Molecular replacement methods were used to solve the str

101 as been determined to 1.9 A resolution using molecular replacement methods.

102 on of the "closed form" GlnBP-Gln complex by molecular replacement methods.

103 to 1.6 A spacing by anomalous scattering and molecular replacement methods.

104 n from electron cryomicroscopy was used as a molecular replacement model for initial phase determinat

105 h respect to the human Fc used as an initial molecular replacement model.

106 Molecular replacement (MR) is one of the most common tec

107 re we show that, contrary to current belief, molecular replacement need not be restricted to the use

108 we establish a comparable method, called NMR molecular replacement (NMR(2)).

109 Neither molecular replacement nor derivative methods had a suffi

110 pid carrier proteins, may also contribute to molecular replacement of disc membrane DHA-phospholipids

111 Moreover, molecular replacement of endogenous PSD-95 with the S561

112 Despite extensive work, molecular replacement or the subsequent rebuilding usual

113 D has been solved to 2.3-A resolution using molecular replacement phases derived from human oxyhemog

114 CD has been solved to 3.0 A resolution using molecular replacement phases derived from the structure

115 was determined to1.9 A resolution using the molecular replacement phasing method.

116 Molecular replacement procedures, which search for place

117 he signal-to-noise ratio in likelihood-based molecular replacement searches has been developed to acc

118 A tungstate derivative confirmed the initial molecular replacement solution and identified an anion b

119 tant has been solved at 1.62 A resolution by molecular replacement starting from the structure of the

120 The structures have been solved using molecular replacement strategies, and the DHPR-NADH-2,6-

121 sential for synaptic potentiation by using a molecular replacement strategy designed to dissociate Ra

122 Using a viral-mediated molecular replacement strategy in rat hippocampal slices

123 pal pyramidal neurons, we used a single-cell molecular replacement strategy to replace all endogenous

124 Using a molecular replacement strategy with RNAi-mediated knockd

125 ral role in X-ray structure determination by molecular replacement, such information is rarely used i

126 The crystal structure has been solved using molecular replacement techniques and refined by simulate

127 To accomplish this, molecular replacement techniques are being used, where n

128 NAT2, aaNAT5b and paaNAT7 was detected using molecular replacement techniques.

129 The resulting model was used to solve by molecular replacement the X-ray structure of l-sfAFP to

130 crystal structure of LbPFK was solved using molecular replacement to 1.86 A resolution.

131 ycogenin and UDP-glucose/Mn2+ were solved by molecular replacement to 1.9 A using the orthorhombic cr

132 himurium bound to GMP has been determined by molecular replacement to 2.2 A resolution.

133 human low molecular weight PTPase solved by molecular replacement to 2.2 A.

134 encoded by the cobA gene, has been solved by molecular replacement to 2.7A resolution.

135 ontaining tripeptide have been determined by molecular replacement to 3.5 A and 2.4 A resolutions, re

136 as determined by X-ray crystallography using molecular replacement to a resolution of 2.9 A.

137 We have used molecular replacement to solve the crystal structure of

138 the X-ray crystallographic phase problem in molecular replacement trials.

139 berculosis antigen 85B (ag85B), initially by molecular replacement using antigen 85C as a probe.

140 activity, was solved at 1.5 A resolution by molecular replacement using as the search model the solu

141 OPS) from Escherichia coli was determined by molecular replacement using coordinates given to us by R

142 A. aeolicus enzyme, which was determined by molecular replacement using E. coli KDO8PS as a model.

143 The structures were solved by molecular replacement using Escherichia coli dUTPase as

144 ine was determined to 2.18 A resolution with molecular replacement using rat PITPalpha (77% sequence

145 The structure was solved by molecular replacement using rat serum mannose-binding pr

146 The structural solution was obtained by molecular replacement using superimposed polyalanine coo

147 structure determined to 2.0 A resolution by molecular replacement using the coordinates of a truncat

148 The structure was solved by molecular replacement using the coordinates of the isomo

149 The structure was solved by molecular replacement using the crystal structure of a m

150 The structure was solved by molecular replacement using the crystal structure of the

151 re obtained, and the structure was solved by molecular replacement using the CsdB coordinates combine

152 at 1.85 A (cubic), respectively, resolved by molecular replacement using the homologous avian infecti

153 m) was determined to a resolution of 2.7A by molecular replacement using the human apo-N-lobe and the

154 murium have been determined by the method of molecular replacement using the known structure of the h

155 the presence of 0.1 M Mg(2+), was solved by molecular replacement using the model of cowpea chloroti

156 se from Bacillus subtilis, was determined by molecular replacement using the muconate lactonizing enz

157 eductase superfamily, has been determined by molecular replacement using the NADPH-bound form of the

158 f the PLP-bound holoenzyme was determined by molecular replacement using the Pseudomonas fluorescens

159 l structure of human sfALR was determined by molecular replacement using the rat sfALR structure.

160 The native structure was solved by molecular replacement using the structure of the homolog

161 C was also determined to 2.9 A resolution by molecular replacement using the TbODC DFMO-bound structu

162 The crystal structure was solved by molecular replacement using the unliganded structure and

163 alpha was determined at 2.3 A resolution by molecular replacement using the wild-type V alpha struct

164 r has been determined to 2.1 A resolution by molecular replacement using truncated mouse ODC (Delta42

165 2-phosphoglycolate (PGL), was determined by molecular replacement using X-ray diffraction data to 2.

166 bitor (K(d) = 0.4 microM) were determined by molecular replacement using X-ray diffraction data to 2.

167 The structure was solved by molecular replacement, using a composite of the parent s

168 Phases were obtained by molecular replacement, using our previously determined r

169 ly, ResQ B-factor profile was used to assist molecular replacement, which resulted in successful solu

170 9-9.0 A) was analyzed using a combination of molecular replacement with an energy-minimized model and

171 AD+(gamma) was solved to 2.7 A resolution by molecular replacement with human class I beta1 beta1 ADH

172 , in fact, a bound Na ion as demonstrated by molecular replacement with Rb+.

173 Molecular replacement with the E.coli DnaK(SBD) model wa

174 merization site, and its structure solved by molecular replacement with the model of fragment D.

175 The initial phasing was done by molecular replacement with the mouse ODC structure.

176 The structure was solved by molecular replacement with the Pseudomonas aeruginosa ca

177 Using data to 2.8 A resolution and molecular replacement with the refined model of the carb

178 that has been solved to 3.1 A resolution by molecular replacement with the structure of a dual funct

179 Molecular replacement with the Thermotoga maritima NifS

180 vative of the native protein, and then using molecular replacement with the unrefined structure as a

181 ns that reach the high accuracy required for molecular replacement without any experimental phase inf