ライフサイエンスコーパス: molten

1 y stable with multiple native conformations (molten).

2 junction and contiguous A-chain residues are molten.

3 upled from a core that is at least partially molten.

4 llization it is completely encapsulated by a molten 1- to 2-nanometer shell of titania that, in liqui

5 y-dispersive x-ray spectroscopy on partially molten Al-Si-Cu-Mg alloy particles during in situ heatin

6 igate reactions of SO(2) at the surface of a molten alkali carbonate eutectic at 683 K.

7 ty up to 95% on catalysts comprising a mixed molten alkali chloride supported on a mildly redox-activ

8 Hence, when a single crystal is molten, all remnants have a unique orientation and thus

9 In the molten alloy system, the insoluble carbon floats to the

10 culations show that the active metals in the molten alloys are atomically dispersed and negatively ch

11 Crystallization of microdroplets of molten alloys could, in principle, present a number of p

12 een made that volcanic reservoirs are rarely molten and only capable of eruption for durations as bri

13 esulting cosmic spherules was oxidized while molten, and quench-crystallized to form spheres of inter

14 l hotspots have been attributed to partially molten asthenosphere, fertile blobs, small-scale convect

15 Here we report the structure of molten basalt up to 60 GPa by means of in situ X-ray dif

16 The reactions of LnCl(3) with molten boric acid result in the formation of Ln[B(4)O(6)

17 reactions of AnCl(3) (An = Pu, Am, Cm) with molten boric acid under the same conditions yield Pu[B(4

18 The key development is the use of a molten borohydride (MEt3BH, M = Na, K) as both the reduc

19 nd fluid outer core, overlain by a partially molten boundary layer.

20 ous carbons through cathodic polarization in molten CaCl2 at temperatures of about 1100 K, which gene

21 aining nitrides were grown from reactions in molten calcium and lithium.

22 ailable silica/carbon (SiO2/C) precursors in molten calcium chloride.

23 m and kinetics of proton transfer in lithium molten carbonate (MC) were investigated.

24 Redox media of molten carbonate or molten metal facilitating the transp

25 y STEP, from iron ore, occurs via Fe(III) in molten carbonate.

26 s, along with the electrical conductivity of molten carbonated peridotite and that of the oceanic upp

27 Molten carbonates are highly inviscid liquids characteri

28 efficiency of SO(2) --> CO(2) conversion by molten carbonates, which appear to be much more reactive

29 h young plates consists of a thin, partially molten, channel of low viscosity that acts to decouple t

30 The compositions of the oxide core and the molten chloride shell control the catalytic activity via

31 Traces of water may be present in the molten chloride under reaction conditions, but the speci

32 is, and chlorine, sodium, and magnesium from molten chlorides.

33 ng longitudinal phonon cooling effect on the molten COD wave front, and the formation of patterns due

34 lass limit, which can be associated with the molten copper sublattice leading to a softening of phono

35 ct synthesis of 2D Mo2 C-on-graphene film by molten copper-catalyzed chemical vapor deposition (CVD)

36 well-ordered core, some proteins exhibit a 'molten core' likely supporting functionally important dy

37 n in the severe FDNPP accident: Melted fuel (molten core)-concrete interactions (MCCIs), incorporatin

38 They formed as molten droplets and, judging from their abundances in ch

39 ume or fireball, it cools and condenses into molten droplets called spherules.

40 tween two molten electrodes and formation of molten droplets.

41 nstable due to frequent sticking between two molten electrodes and formation of molten droplets.

42 The molten events are constrained to individual particles, m

43 Direct visualization at 1873 K of 0% to 8% molten FeAl droplets suspended in a SiO2 enriched oxide

44 ('/' = physisorbed, '-' = chemisorbed), from molten Field's metal (Bi-In-Sn) and Bi-Sn alloys.

45 Synthetic reactions in molten fluxes have proven to be an excellent route to ne

46 0-0.26, y = 0-4.0) has been isolated from a molten gallium flux reaction.

47 bove 650 degrees C, Ag(+) dissolves into the molten glass frit - key for enabling deposition of metal

48 ated frits are used), which are converted to molten glass in a continuous electrical glass-melting fu

49 cap, a layer of reacting feed on top of the molten glass.

50 factants suspended in oil spontaneously form molten glasses with nanometre-size domains of sugar and

51 Dry molten globular (DMG) intermediates, an expanded form of

52 he first variant was only weakly active, had molten globular characteristics, and was monomeric at 25

53 at contains an off-pathway intermediate with molten globular characteristics.

54 to function as a monomer, and the ability of molten globular proteins to carry out complex reactions.

55 a model peptide that exists in the bulk as a molten globular state consisting of many interconverting

56 n of an early crust, and the protein in this molten globular state creates a cohesive network encapsu

57 dynamics around a protein in its native and molten globular states, using a tryptophan scan by site-

58 rarr2;MG) leading to a transiently populated molten globule (MG) state.

59 f the folding transitions from native (N) to molten globule (MG) to kinetic intermediates (U) pathway

60 rmediates, of which an important type is the molten globule (MG).

61 The molten globule +8 shows a very specific transition.

62 ggest a possible link between an equilibrium molten globule and a functional intermediate that may be

63 context of previous studies of the alpha-LA molten globule and can be used to reconcile apparent dis

64 ce, the slowest step is unfolding of the wet molten globule and involves a solvated transition state.

65 ng to misfolding, the barrier separating the molten globule and native states increases, although the

66 guiding a large structural transition from a molten globule apo-state to a compact holoconformation.

67 e the structural preferences of the alpha-LA molten globule at pH 7 at the level of individual residu

68 The molten globule at pH 7 is generally less stable than tha

69 ational ensemble that describes the alpha-LA molten globule at these two pH values.

70 We propose that "local" molten globule behavior optimizes detoxication enzymes.

71 The molten globule characteristics of NCBD are thus restrict

72 The molten globule characteristics of the C-terminal domain

73 that the almost fully folded protein retains molten globule characteristics with severe NMR line broa

74 ha-helix-rich monomeric precursor state with molten globule characteristics, converting in vitro into

75 onclude that at pH 4-5, 3betaHSD2 takes on a molten globule conformation that promotes the dual funct

76 illebrand disease mutations induce misfolded molten globule conformations of the A1 domain.

77 of the A1 domain to misfold to pathological molten globule conformations that differentially alter t

78 ues that may influence the properties of the molten globule differently at low and neutral pH.

79 assumption that many other proteins populate molten globule folding intermediates.

80 1)-AT involves a cooperative transition to a molten globule form, followed by a non-cooperative trans

81 f apoleghemoglobin at least, the equilibrium molten globule formed under destabilizing conditions at

82 ically structured energy landscape to form a molten globule in a few seconds.

83 d Escherichia coli enzyme, which exists as a molten globule in the absence of ligands, and a well fol

84 sion to VWF in hemostasis, unfolds through a molten globule intermediate in an apparent three-state m

85 se results suggest that the structure of the molten globule intermediate of apoleghemoglobin is more

86 L/ES and protease Lon compete for binding to molten globule intermediate of DHFR, resulting in a pecu

87 ter than that observed for the highly pliant molten globule intermediate states.

88 s the unfolding mechanism by eliminating the molten globule intermediate that is seen in wild type un

89 rs exhibits many of the characteristics of a molten globule intermediate with some helical character

90 state); this large compliance means that the molten globule is more deformable and the unfolding rate

91 lpha-lactalbumin (alpha-LA), the equilibrium molten globule is most often studied at pH 2, the so-cal

92 te may not be the best model for the kinetic molten globule observed during refolding of alpha-LA.

93 fferences from the well-characterized pH 4.1 molten globule of apoMb.

94 s, we show that the dense phase has either a molten globule or a crystalline structure, depending on

95 accomplished primarily by destabilizing the molten globule rather than stabilizing the metastable na

96 oinhibition where the activation box and the molten globule region act synergistically to impair the

97 The molten globule region and the activation box become less

98 onal autoinhibitory element in the form of a molten globule region within the linker between RGSL and

99 ion of the structure, generating a monomeric molten globule species that retains its native helical c

100 sed NMR studies reveal that OBP4 exists in a molten globule state and binding of indole induces a dra

101 l flexibility and exists in a highly dynamic molten globule state at physiological temperature.

102 folding and stability, although a link to a molten globule state has not previously been shown.

103 s in the pressure range of 0-3 kbar, where a molten globule state is formed.

104 modynamically unstable and several acquire a molten globule state near human physiological temperatur

105 zation by direct binding to concavity in the molten globule state of a protein.

106 onsistent with an experimental report of the molten globule state of ApoE4, simulations identify mult

107 Unlike natively folded proteins, the molten globule state of apomyoglobin is compliant (large

108 ble of subcompact conformers, similar to the molten globule state of human alpha-lactalbumin, demonst

109 The molten globule state of human serum retinol-binding prot

110 characteristics similar to those of the pH 2 molten globule state of the protein.

111 denatured state at pH 2.6 through the stable molten globule state pH approximately 4.1 to the folded

112 transitions observed in PimA might reflect a molten globule state that confers to PimA, a higher affi

113 into the membrane, which is favoured by the molten globule state under investigated acidic condition

114 rd pH 2, at which alpha-lactalbumin adopts a molten globule state, a small but increasing proportion

115 At pH 3, the ovotransferrin adopted a molten globule state, associated with a significant incr

116 a class of intermediates referred to as the molten globule state.

117 ts associated with the transition across the molten globule state.

118 A close similarity between equilibrium molten globule states and kinetic species observed durin

119 Model proteins can exist in native and molten globule states and participate in functional and

120 rtant question in protein folding is whether molten globule states formed under equilibrium condition

121 eased exchange protection in the equilibrium molten globule states near pH 4.

122 ated the response to force of the native and molten globule states of apomyoglobin along different pu

123 ontrast to the dynamic but otherwise similar molten globule states of proteins.

124 ompared to earlier experimental estimates in molten globule states, and is consistent with more recen

125 Finally, from native to molten globule states, the hydration water networks loos

126 ical unfolding pathways at low force akin to molten globule states.

127 l protein of apomyoglobin in both native and molten globule states.

128 for the establishment of new topologies and molten globule states; their effects, however, can be in

129 This transition from the helical molten globule to beta-conformation has striking similar

130 al changes that have been characterized as a molten globule transition.

131 ther proteins that were observed to sample a molten globule under similar conditions.

132 ative-favoring conditions proceeds through a molten globule unfolded monomer state, with a nucleation

133 esidual secondary structures, free NCBD is a molten globule with a helical content similar to that in

134 st in a wide range of conformations or in a "molten globule" state.

135 on of bis-ANS to quantify the population of "molten globule" states.

136 ics ascribed to the recently postulated "dry molten globule".

137 The molten globule, a conformational ensemble with significa

138 Under native conditions, free pVHL is a molten globule, but it is stabilized in the E3 complex.

139 re becomes solvated only later in a late wet molten globule, IL, which precedes the unfolded form.

140 e of apoMb at pH 6 has been referred to as a molten globule, the data presented here reveal significa

141 hione transferase A1-1 (GSTA1-1), exploits a molten globule-like active site to achieve remarkable ca

142 lowed by progressive unfolding of a compact, molten globule-like denatured state ensemble as the temp

143 weakly structured regions, such as loops and molten globule-like domains that are inaccessible in con

144 -to-the-barrel ILV cluster (cluster 3) imply molten globule-like packing.

145 domain, despite its reported aggregation and molten globule-like properties.

146 Induction of a low-pH-induced, molten globule-like state inhibited glycolipid intermemb

147 the photoactivated form of OCP represents a molten globule-like state that is characterized by incre

148 autoinhibited homodimeric chaperones adopt a molten globule-like state that transiently exposes the s

149 ures up to 200MPa resulted in a structurally molten globule-like state where PepX maintained its seco

150 0, generating a conformationally fluctuating molten globule-like state.

151 baseline region in the absence of populated molten globule-like states.

152 NMR studies suggest a molten globule-like structure also in the dimeric state.

153 -4 and C(H)2 domains, which unfold to form a molten globule-like structure that is aggregation-prone.

154 Thus, NaClO(4) denatures by inducing a molten globule-like structure that seems completely off-

155 rmation of arrestin-1, possibly to a dynamic molten globule-like structure.

156 large tetrameric enzyme DAHP synthase to a 'molten globule-like' region surrounding the active site.

157 is shown to possess a novel combination of a molten globule-type C-terminal domain and an N-terminal

158 Thus, it has some features of a molten globule.

159 o folding that has long been thought to be a molten globule.

160 tive conformation reminiscent of the protein molten globule.

161 of the alpha-domain to the stability of the molten globule.

162 low-pH urea unfolded state, but it is not a molten globule.

163 he properties of an intrinsically disordered molten globule.

164 n contrast, apoFixLH presented features of a molten globule.

165 pecies result in an inactive apoprotein with molten-globule characteristics.

166 Apart from the native state, native-like and molten-globule states have been identified; these states

167 ediate was attributed to the appearance of a molten-globule-like (MG) state.

168 In order to understand the origins of this molten-globule-like compaction, we have characterized a

169 after a rapid jump to native conditions) and molten globules (arising due to mutations or cosolvents)

170 adopted by these intermediates, also called molten globules (MG), to understand protein folding.

171 suggest that these are general properties of molten globules and could have important implications fo

172 unt for the dramatic compaction observed for molten globules and the "physiological" unfolded state.

173 results suggest that the rapid formation of molten globules and the variable behavior of those globu

174 kin to ANS, which fluoresces upon binding to molten globules and thermal denaturation intermediates.

175 -bundle protein that forms collapsed, stable molten globules but lacks a uniquely folded structure-tr

176 sulfide mutants are less stable and exist as molten globules in the monomeric state.

177 ce in comparisons of equilibrium and kinetic molten globules of other proteins.

178 Structural investigations of molten globules provide an important contribution toward

179 distributions for pressure- and pH-populated molten globules shows them to be remarkably similar desp

180 myloid fibril formation, and not with stable molten globules states or amorphously aggregating specie

181 artially folded intermediate states, such as molten globules, are compliant and can deform elasticall

182 e disulfide bridges and the establishment of molten globules.

183 ed to produce partially unfolded equilibrium molten globules.

184 ty of the core, suggesting that they are dry molten globules.

185 ocess results in the formation of aggregated molten globules.

186 ers maintaining properties of intermolecular molten globules.

187 or guest entrapment in these hexamers, using molten guest molecules as solvent and allowing the capsu

188 Water is efficiently split to hydrogen by molten hydroxide electrolysis, and chlorine, sodium, and

189 oduced by electrolysis of air and steam in a molten hydroxide suspension of nano-Fe2O3.

190 The molten ink undergoes directional solidification upon pri

191 e, salt melt synthesis (SMS) which employs a molten inorganic salt as the medium emerges as an import

192 c materials) form stable colloids in various molten inorganic salts.

193 It is proposed that a "molten interface" structure, flexible enough to accommod

194 thought to arise from thermal convection of molten iron alloy in the outer core, but recent density

195 ure-evolution of nickel partitioning between molten iron and molten silicates, indicating that melt c

196 to obtain the pair distribution function of molten K(2)S(5) and model the length of S(n)(2-) chains

197 we interpret the conductor to be a partially molten layer capped by an impermeable frozen lid that is

198 s well experimental data on the width of the molten layer versus temperature for the Al plane surface

199 We discovered that molten Li metal can infuse into the straight channels of

200 nsforms CO2-gas dissolved in a 750 degrees C molten Li2CO3, by electrolysis, into O2-gas at a nickel

201 n in solid matrix and rising red emission in molten liquid phase.

202 there are no known examples of solvent-less (molten) liquids of functional metalloproteins.

203 e employed is stable against highly reactive molten lithium and, via a conformal layer of zinc oxide

204 coating to render the surface lithiophilic, molten lithium can be drawn into the matrix, affording a

205 ng metallic lithium anode design by infusing molten lithium into a polymeric matrix.

206 trong coupling between n in K(2)S(n) and the molten local structure, implying that the S(n)(2-) chain

207 The semi-molten M7C3 carbide contains unmelted shell and several

208 s semimetallic at the conditions of the deep molten mantle of early Earth and super-Earths, raising t

209 boundary conditions to guide the flow of the molten material into the desired geometry before solidif

210 th different pore structures as preforms for molten metal (Al alloy) infiltration.

211 ture metals (In, Ga, Sn, Pb), produce stable molten metal alloy catalysts for pyrolysis of methane in

212 xtent of iron isotopic fractionation between molten metal and silicate under high pressure-temperatur

213 Redox media of molten carbonate or molten metal facilitating the transportation of ions off

214 were thermally decomposed in the presence of molten metal nanoparticles and coordinating ligands.

215 Both SLS and VLS methods make use of molten metal nanoparticles to catalyse the nucleation an

216 nanoparticle self-stabilization mechanism in molten metal.

217 tly after the birth of the Solar System, the molten metallic cores of many small planetary bodies con

218 Molten mixtures of lithium chloride and metallic lithium

219 es on reproducible Raman spectra recorded on molten mixtures whose compositions are identical to thos

220 e-mantle equilibration in a largely to fully molten Moon.

221 gy, the crystallographic structure, the semi-molten morphology and the stacking faults of the primary

222 lumina content from the Raman spectra of the molten NaF-AlF3-CaF2-Al2O3 electrolytes.

223 ature Li/O2 battery using a lithium anode, a molten nitrate-based electrolyte (e.g., LiNO3-KNO3 eutec

224 airs block prion nucleation by disassembling molten oligomers and binding mature oligomers.

225 n of disordered, non-beta-sheet-like soluble molten oligomers as early intermediates--a proposal that

226 revents conformational rearrangements within molten oligomers that enable de novo prionogenesis and c

227 We introduce the use of pure molten ortho-phosphoric acid (o-H3PO4) as an electrolyte

228 Molten oxide electrolysis (MOE) is an electrometallurgic

229 nge due to material exchange in liquid metal-molten oxide systems is presented.

230 Cooling rates of molten PbTe-CdTe compositions play a determinant role in

231 ound that the metal coating dissolved in the molten piece of Li and diffused into the bulk Li metal,

232 t is possible to dissolve these compounds in molten poly(hydroxybutyrate) (PHB), having a hydroxyvale

233 eta-alumina as the electrolyte to separate a molten potassium metal anode and a sulfur cathode is pre

234 The porosity of the partially molten region beneath ocean ridges is therefore controll

235 ash-form tektites, glassy stones formed from molten rock ejected from asteroid impacts.

236 panied by the production of large volumes of molten rock.

237 lava-the remnant of a once-swollen river of molten rock.

238 med olivine aggregates and sheared partially molten rocks.

239 oes erupt volatiles such as water instead of molten rocks.

240 tanding of transport properties in partially molten rocks.

241 ng-ranged charge-density oscillations in the molten salt around solute particles, preventing their ag

242 l nuclear fuel reprocessing, metal refining, molten salt batteries and electric power cells.

243 ery comprising a negative electrode of Mg, a molten salt electrolyte (MgCl(2)-KCl-NaCl), and a positi

244 on anode immersed in an immiscible secondary molten salt electrolyte disposed above molten stibnite,

245 ctromagnetic field, and the highly corrosive molten salt electrolyte to deal with.

246 rises a liquid lithium negative electrode, a molten salt electrolyte, and a liquid antimony-lead allo

247 ide, is stable and moderately soluble in the molten salt electrolyte.

248 earch in the field with alkali metal nitrate molten salt electrolytes and operate the battery above t

249 ical behavior of europium(III) chloride in a molten salt eutectic, 3LiCl-2KCl, over a temperature ran

250 The non-molten salt ion exchange method used to prepare Li2Mg2P3

251 ofluid type colloidal suspension of Li8 in a molten salt matrix.

252 al sensor for lanthanides and actinides into molten salt media.

253 This study provides direct evidence of the molten salt state of Na2 WO4 , which can form OH radical

254 This reaction may proceed on molten salt state surfaces owing to the lower melting po

255 e-crystalline hexagonal plates by coupling a molten salt synthesis with ultrasonic spray pyrolysis (U

256 presented with emphasis on hydrothermal and molten salt synthesis.

257 t lower temperatures can be applied to other molten salt systems and is also promising for waste glas

258 Using carefully monitored molten salt techniques, it was possible to eradicate the

259 l deposition of silicon p-n junctions all in molten salt.

260 of high-quality Si films from a CaCl2 -based molten salt.

261 Here, we show that a molten-salt flux scheme can be used to synthesize large

262 of control, robustness, and scalability, the molten-salt flux scheme can provide high-quality TiO2 na

263 Molten salts (MSs) are an attractive medium for chemical

264 degrees C by using low-melting-point ternary molten salts CaCl2 -MgCl2 -NaCl, which still retains hig

265 ate-temperature (200 to 350 degrees Celsius) molten salts containing caesium or potassium cations ena

266 ids since the literature on room temperature molten salts experienced the rapid increase in number of

267 Proposals relying on fluoride-based molten salts have suffered from low product quality due

268 nic liquids are a family of non-conventional molten salts that can act as templates and precursors to

269 eristic of ionic liquids (or low-temperature molten salts) is that they exert no measurable vapour pr

270 bundant and inexpensive Si source soluble in molten salts, at a low temperature of 650 degrees C by u

271 on mobilities as high as those in liquids or molten salts, have been employed as solid-state electrol

272 in investigating the structure of corrosive molten salts, such as the cryolite-based melts widely us

273 degrees C) via electrochemical reduction in molten salts.

274 eactivity and unfavorably high solubility in molten salts.

275 Initial oxidation produces a molten silica shell that acts as an autocatalytic 'nanor

276 nickel partitioning between molten iron and molten silicates, indicating that melt compressibility c

277 to the core, forming a large phase-separated molten silicon domain that is drawn into the crystalline

278 idge that we interpret as originating from a molten sill at present accreting the lower oceanic crust

279 However, seismic images of molten sills within the lower crust have been elusive.

280 We report the results of a study of molten sodium carbonate (Na2CO3) which combines high ene

281 the current work, the physical chemistry of molten solutions of lithium chloride and metallic lithiu

282 Dyes that are soluble in molten sorbitol become oriented as the crystallization f

283 ndrules are the millimetre-scale, previously molten, spherules found in most meteorites.

284 strong forces induce a phase transition to a molten state consisting of unhybridized single strands.

285 , a major step towards obtaining data on the molten state.

286 [2+2] addition have focused on solid-state, molten-state, or host-guest systems under ultraviolet-li

287 While glasses formed by quenching the molten states of inorganic non-metallic, organic, and me

288 rocess that directly converts semiconducting molten stibnite (Sb2S3) into pure (99.9%) liquid antimon

289 ndary molten salt electrolyte disposed above molten stibnite, thereby blocking electronic shorting ac

290 ntimony pools beneath cathodically polarized molten stibnite.

291 another and indicate that the dimers adopt a molten structure.

292 polypeptides are nucleated by a native-like molten subdomain containing Cys(A20) and Cys(B19).

293 nformation, in contrast to the hypothesis of molten tertiary packing.

294 the melting temperature unless all solid is molten, thus nanoparticles have sharp melting peaks duri

295 in 4-ethylpyridine, tri-n-butylphosphine, or molten tri-n-octylphosphine oxide solution results in na

296 thesized via crystallization from melt: as a molten (undoped) CeO2 nanoparticle is cooled, nucleating

297 es (>3140 kelvin) and chemical reactivity of molten UO2 have prevented structural studies.

298 ution function measurements of hot solid and molten UO2.

299 equation that accounts for the spreading of molten wax in paper.

300 nd CdTe compound semiconductors dissolved in molten ZnCl(2) and equimolar CdCl(2)-KCl, respectively,